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  1. Article ; Online: Reply from Stephen J. Bailey, Paulo G. Gandra, Andrew M. Jones, Michael C. Hogan and Leonardo Nogueira.

    Bailey, Stephen J / Gandra, Paulo G / Jones, Andrew M / Hogan, Michael C / Nogueira, Leonardo

    The Journal of physiology

    2020  Volume 598, Issue 8, Page(s) 1643–1644

    MeSH term(s) Animals ; Fatigue ; Mice ; Sodium Nitrite
    Chemical Substances Sodium Nitrite (M0KG633D4F)
    Language English
    Publishing date 2020-03-05
    Publishing country England
    Document type Letter ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 3115-x
    ISSN 1469-7793 ; 0022-3751
    ISSN (online) 1469-7793
    ISSN 0022-3751
    DOI 10.1113/JP279621
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.65: Show issues Location:
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  2. Article ; Online: Benchmarked approaches for reconstruction of in vitro cell lineages and in silico models of C. elegans and M. musculus developmental trees.

    Gong, Wuming / Granados, Alejandro A / Hu, Jingyuan / Jones, Matthew G / Raz, Ofir / Salvador-Martínez, Irepan / Zhang, Hanrui / Chow, Ke-Huan K / Kwak, Il-Youp / Retkute, Renata / Prusokiene, Alisa / Prusokas, Augustinas / Khodaverdian, Alex / Zhang, Richard / Rao, Suhas / Wang, Robert / Rennert, Phil / Saipradeep, Vangala G / Sivadasan, Naveen /
    Rao, Aditya / Joseph, Thomas / Srinivasan, Rajgopal / Peng, Jiajie / Han, Lu / Shang, Xuequn / Garry, Daniel J / Yu, Thomas / Chung, Verena / Mason, Michael / Liu, Zhandong / Guan, Yuanfang / Yosef, Nir / Shendure, Jay / Telford, Maximilian J / Shapiro, Ehud / Elowitz, Michael B / Meyer, Pablo

    Cell systems

    2021  Volume 12, Issue 8, Page(s) 810–826.e4

    Abstract: ... challenge using in vitro experimental intMEMOIR recordings and in silico data for a C. elegans lineage tree ...

    Abstract The recent advent of CRISPR and other molecular tools enabled the reconstruction of cell lineages based on induced DNA mutations and promises to solve the ones of more complex organisms. To date, no lineage reconstruction algorithms have been rigorously examined for their performance and robustness across dataset types and number of cells. To benchmark such methods, we decided to organize a DREAM challenge using in vitro experimental intMEMOIR recordings and in silico data for a C. elegans lineage tree of about 1,000 cells and a Mus musculus tree of 10,000 cells. Some of the 22 approaches submitted had excellent performance, but structural features of the trees prevented optimal reconstructions. Using smaller sub-trees as training sets proved to be a good approach for tuning algorithms to reconstruct larger trees. The simulation and reconstruction methods here generated delineate a potential way forward for solving larger cell lineage trees such as in mouse.
    MeSH term(s) Algorithms ; Animals ; Benchmarking ; Caenorhabditis elegans/genetics ; Cell Lineage/genetics ; Computer Simulation ; Mice
    Language English
    Publishing date 2021-06-18
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2854138-8
    ISSN 2405-4720 ; 2405-4712
    ISSN (online) 2405-4720
    ISSN 2405-4712
    DOI 10.1016/j.cels.2021.05.008
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  3. Article ; Online: Unpicking the determinants of amide NHO[double bond, length as m-dash]C hydrogen bond strength with diphenylacetylene molecular balances.

    Luccarelli, James / Jones, Ian M / Thompson, Sam / Hamilton, Andrew D

    Organic & biomolecular chemistry

    2017  Volume 15, Issue 43, Page(s) 9156–9163

    Abstract: Hydrogen bonding plays an essential part in dictating the properties of natural and synthetic materials. Secondary amides are well suited to cross-strand interactions through the display of both hydrogen bond donors and acceptors and are prevalent in ... ...

    Abstract Hydrogen bonding plays an essential part in dictating the properties of natural and synthetic materials. Secondary amides are well suited to cross-strand interactions through the display of both hydrogen bond donors and acceptors and are prevalent in polymers such as proteins, nylon, and Kevlar™. In attempting to measure hydrogen bond strength and to delineate the stereoelectronic components of the interaction, context frequently becomes vitally important. This makes molecular balances - systems in which direct comparison of two groups is possible - an appealing bottom up approach that allows the complexity of larger systems to be stripped away. We have previously reported a family of single molecule conformational switches that are responsive to diverse stimuli including Brønsted and Lewis acids, anions, and redox gradients. In this work we assess the ability of the scaffold, based on a 2,6-disubstituted diphenylacetylene, to measure accurately the difference in hydrogen bond strength between variously functionalised amides. In all of the examples investigated hydrogen bond strength closely correlate to measures of Brønstead acidity suggesting that the scaffold is well-suited as a platform for the accurate determination of bond strength in variously substituted systems.
    Language English
    Publishing date 2017-11-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2097583-1
    ISSN 1477-0539 ; 1477-0520
    ISSN (online) 1477-0539
    ISSN 1477-0520
    DOI 10.1039/c7ob02026k
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  4. Article ; Online: Obituary: Dr. Alexander M.C. Macgregor, "a giant in the field.".

    Jones, Kenneth B

    Obesity surgery

    2012  Volume 22, Issue 1, Page(s) 3

    MeSH term(s) Bariatric Surgery/history ; History, 20th Century ; History, 21st Century ; Humans ; Male ; Obesity/surgery ; Societies, Medical ; United States
    Language English
    Publishing date 2012-01
    Publishing country United States
    Document type Biography ; Editorial ; Historical Article
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-011-0550-7
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3381: Show issues Location:
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  5. Article ; Online: Commentary on McGillis Hall, L., Lalonde, M., Kashin, J., Yoo, C., & Moran, J. (2017) Changing nurse licensing examinations: media analysis and implication of the Canadian experience.

    Johansen, C / Knowles, B / Jones, D / Dickison, P

    International nursing review

    2018  Volume 65, Issue 2, Page(s) 159–160

    MeSH term(s) Canada
    Language English
    Publishing date 2018-03-11
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 80342-x
    ISSN 1466-7657 ; 0020-8132
    ISSN (online) 1466-7657
    ISSN 0020-8132
    DOI 10.1111/inr.12445
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  6. Article ; Online: Contrasting reactivity of anionic boron- and gallium-containing NHC analogues: E-C vs. E-M bond formation (E = B, Ga).

    Protchenko, Andrey V / Saleh, Liban M A / Vidovic, Dragoslav / Dange, Deepak / Jones, Cameron / Mountford, Philip / Aldridge, Simon

    Chemical communications (Cambridge, England)

    2010  Volume 46, Issue 45, Page(s) 8546–8548

    Abstract: The anionic Group 13 NHC analogues [(CHNDipp)(2)E](-) (E = B or Ga) display contrasting reactivity towards the half-sandwich titanium imido complex Cp*TiCl(NtBu)py; while the gallium system undergoes salt metathesis yielding the first example of a ... ...

    Abstract The anionic Group 13 NHC analogues [(CHNDipp)(2)E](-) (E = B or Ga) display contrasting reactivity towards the half-sandwich titanium imido complex Cp*TiCl(NtBu)py; while the gallium system undergoes salt metathesis yielding the first example of a titanium gallyl compound, the more nucleophilic boryl anion generates a dearomatized pyridyl fragment via attack at the ligand 2-position.
    Language English
    Publishing date 2010-12-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472881-3
    ISSN 1364-548X ; 1359-7345 ; 0009-241X
    ISSN (online) 1364-548X
    ISSN 1359-7345 ; 0009-241X
    DOI 10.1039/c0cc02572k
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  7. Article ; Online: Rhodium-carbon bond energies in Tp'Rh(CNneopentyl)(CH2X)H: quantifying stabilization effects in M-C bonds.

    Jiao, Yunzhe / Evans, Meagan E / Morris, James / Brennessel, William W / Jones, William D

    Journal of the American Chemical Society

    2013  Volume 135, Issue 18, Page(s) 6994–7004

    Abstract: ... crystallography. Relative Rh-C bond energies are calculated using previously established kinetic techniques, and ... two separate linear correlations are observed versus known C-H bond strengths, one for the parent ... of the strengths of the β-C-H bonds. The DFT calculations of the metal-carbon bond strengths in these Rh-CH2X ...

    Abstract A series of substituted methyl derivatives of the type Tp'Rh(CNneopentyl)(CH2X)H (CH2X = CH2C(═O)CH3, CH2C≡CCH3, CH2O-t-Bu, CH2CF3, CH2F, CHF2) was synthesized either by photolysis of Tp'Rh(CNneopentyl)(PhNCNneopentyl) in neat CH3X or by exchange with the labile hydrocarbon in Tp'Rh(CNneopentyl)(n-pentyl)H or Tp'Rh(CNneopentyl)(CH3)H. Only a single product was observed in each case. Clean reductive elimination was observed for all compounds in C6D6. Structures of these complexes and their corresponding chlorinated derivatives have been characterized by NMR spectroscopy, elemental analysis, and X-ray crystallography. Relative Rh-C bond energies are calculated using previously established kinetic techniques, and two separate linear correlations are observed versus known C-H bond strengths, one for the parent hydrocarbons, and one for the substituted hydrocarbons. Both correlations have slopes of 1.4, and are separated vertically by 7.5 kcal mol(-1) (-CH2X above -CxHy). In addition, it is now clear that preferences for linear vs branched olefin insertion products in substituted derivatives can be predicted on the basis of the strengths of the β-C-H bonds. The DFT calculations of the metal-carbon bond strengths in these Rh-CH2X derivatives with α-substitution show a trend that is in good agreement with the experimental results.
    MeSH term(s) Carbon/chemistry ; Models, Molecular ; Molecular Structure ; Organometallic Compounds/chemical synthesis ; Organometallic Compounds/chemistry ; Rhodium/chemistry
    Chemical Substances Organometallic Compounds ; Carbon (7440-44-0) ; Rhodium (DMK383DSAC)
    Language English
    Publishing date 2013-05-08
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/ja400966y
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    In stock of ZB MED Bonn / Germany

    Z 4' 55/32: Show issues
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  8. Article ; Online: Reversible methanol addition to copper Schiff base complexes: a kinetic, structural and spectroscopic study of reactions at azomethine C[double bond, length as m-dash]N bonds.

    Zhang, Wuyu / Saraei, Nina / Nie, Hanlin / Vaughn, John R / Jones, Alexis S / Mashuta, Mark S / Buchanan, Robert M / Grapperhaus, Craig A

    Dalton transactions (Cambridge, England : 2003)

    2016  Volume 45, Issue 40, Page(s) 15791–15799

    Abstract: The reversible methanolysis of an azomethine C[double bond, length as m-dash]N in a series ...

    Abstract The reversible methanolysis of an azomethine C[double bond, length as m-dash]N in a series of copper(ii) Schiff base complexes has been investigated through combined spectroscopic, structural, and kinetic studies. Pentadentate copper(ii) complexes [L
    Language English
    Publishing date 2016-10-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472887-4
    ISSN 1477-9234 ; 1364-5447 ; 0300-9246 ; 1477-9226
    ISSN (online) 1477-9234 ; 1364-5447
    ISSN 0300-9246 ; 1477-9226
    DOI 10.1039/c6dt01955b
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  9. Article: Dual interaction of JAM-C with JAM-B and alpha(M)beta2 integrin: function in junctional complexes and leukocyte adhesion.

    Lamagna, Chrystelle / Meda, Paolo / Mandicourt, Guillaume / Brown, James / Gilbert, Robert J C / Jones, E Yvonne / Kiefer, Friedemann / Ruga, Pilar / Imhof, Beat A / Aurrand-Lions, Michel

    Molecular biology of the cell

    2005  Volume 16, Issue 10, Page(s) 4992–5003

    Abstract: ... with its leukocyte counter-receptor alpha(M)beta2 integrin. We demonstrate that the modulation of JAM-C localization ... junctional molecules and as integrin ligands. Here we show that JAM-B and JAM-C undergo heterophilic ... interaction in cell-cell contacts and that JAM-C is recruited and stabilized in junctional complexes by JAM-B ...

    Abstract The junctional adhesion molecules (JAMs) have been recently described as interendothelial junctional molecules and as integrin ligands. Here we show that JAM-B and JAM-C undergo heterophilic interaction in cell-cell contacts and that JAM-C is recruited and stabilized in junctional complexes by JAM-B. In addition, soluble JAM-B dissociates soluble JAM-C homodimers to form JAM-B/JAM-C heterodimers. This suggests that the affinity of JAM-C monomers to form dimers is higher for JAM-B than for JAM-C. Using antibodies against JAM-C, the formation of JAM-B/JAM-C heterodimers can be abolished. This liberates JAM-C from its vascular binding partner JAM-B and makes it available on the apical side of vessels for interaction with its leukocyte counter-receptor alpha(M)beta2 integrin. We demonstrate that the modulation of JAM-C localization in junctional complexes is a new regulatory mechanism for alpha(M)beta2-dependent adhesion of leukocytes.
    MeSH term(s) Animals ; Cell Adhesion/physiology ; Cell Adhesion Molecules/genetics ; Cell Adhesion Molecules/metabolism ; Cell Line ; Coculture Techniques ; Cricetinae ; Cricetulus ; Endothelium/physiology ; Endothelium/ultrastructure ; Green Fluorescent Proteins/genetics ; Humans ; Immunoglobulins/genetics ; Immunoglobulins/metabolism ; Intercellular Junctions/physiology ; Intercellular Junctions/ultrastructure ; Leukocytes/physiology ; Leukocytes/ultrastructure ; Macrophage-1 Antigen/metabolism ; Mice ; Mice, Inbred C57BL ; Microscopy, Immunoelectron ; Oligopeptides ; Peptides/genetics ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/metabolism
    Chemical Substances Cell Adhesion Molecules ; Immunoglobulins ; Macrophage-1 Antigen ; Oligopeptides ; Peptides ; Recombinant Fusion Proteins ; enhanced green fluorescent protein ; Green Fluorescent Proteins (147336-22-9) ; FLAG peptide (98849-88-8)
    Language English
    Publishing date 2005-10
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 1098979-1
    ISSN 1939-4586 ; 1059-1524
    ISSN (online) 1939-4586
    ISSN 1059-1524
    DOI 10.1091/mbc.E05-04-0310
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2853: Show issues Location:
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    Zs.MO 410: Show issues

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  10. Article ; Online: Response to Anderson RE, Young V, Stewart M, Robertson C, Dancer SJ, 'Cleanliness audit of clinical surfaces and equipment: who cleans what?'.

    Jones, K / Banfield, K / Weightman, N C / Kerr, K G

    The Journal of hospital infection

    2011  Volume 79, Issue 4, Page(s) 379–380

    MeSH term(s) Decontamination/statistics & numerical data ; Environmental Microbiology ; Equipment and Supplies/microbiology ; Health Services Research ; Humans ; Quality Assurance, Health Care/methods
    Language English
    Publishing date 2011-12
    Publishing country England
    Document type Comment ; Letter
    ZDB-ID 779366-2
    ISSN 1532-2939 ; 0195-6701
    ISSN (online) 1532-2939
    ISSN 0195-6701
    DOI 10.1016/j.jhin.2011.07.001
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