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Article ; Online: A prospective cohort study of newborns born to mothers with serum Toxoplasma gondii immunoglobulin M positivity during pregnancy.

Hijikata, Midori / Morioka, Ichiro / Okahashi, Aya / Nagano, Nobuhiko / Kawakami, Kaori / Komatsu, Atsushi / Kawana, Kei / Ohyama, Shohei / Fujioka, Kazumichi / Tanimura, Kenji / Deguchi, Masashi / Sasai, Miwa / Yamamoto, Masahiro / Yamada, Hideto

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy

2021 Volume 28, Issue 4, Page(s) 486–491

Abstract: ... gondii) immunoglobulin (Ig) M-positive mothers and to clarify the incidences of serum T. gondii IgM or ...

Abstract	Introduction: The aims were to investigate the clinical characteristics of Toxoplasma gondii (T. gondii) immunoglobulin (Ig) M-positive mothers and to clarify the incidences of serum T. gondii IgM or blood T. gondii DNA positivity in newborns born to the mothers and the actual congenital T. gondii infection. Methods: Mothers with T. gondii IgM positivity and newborns born to the mothers from 2013 to 2020 were prospectively investigated. Serum T. gondii IgG and IgM were measured by enzyme-linked immunosorbent assay. Blood T. gondii DNA was detected by semi-nested polymerase chain reaction. Congenital T. gondii infection was diagnosed based on clinical characteristic manifestations with serum T. gondii IgG positivity at any age or T. gondii IgG positivity after 12 months of age. Results: Among 71 T. gondii IgM-positive mothers, including one with triplets, 41% had low T. gondii IgG avidity index and 73% received maternal therapy. Among 73 newborns who were examined for serum T. gondii IgG and IgM at birth, none had clinical manifestations, and one (1.4%) had T. gondii IgM positivity. Among 32 newborns who were examined for blood T. gondii DNA at birth, two (6.3%) were positive. All patients with serum T. gondii IgM or blood T. gondii DNA positivity showed T. gondii IgG negativity within 12 months of age. Conclusions: A few newborns born to T. gondii IgM-positive mothers were suspected of having congenital T. gondii infection based on serum T. gondii IgM or blood T. gondii DNA testing at birth. However, none developed congenital T. gondii infection.
MeSH term(s)	Antibodies, Protozoan ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Immunoglobulin M ; Infant, Newborn ; Mothers ; Pregnancy ; Prospective Studies ; Toxoplasma/genetics
Chemical Substances	Antibodies, Protozoan ; Immunoglobulin M
Language	English
Publishing date	2021-12-17
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1355399-9
ISSN	1437-7780 ; 1341-321X
ISSN (online)	1437-7780
ISSN	1341-321X
DOI	10.1016/j.jiac.2021.12.005
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Zs.A 5236: Show issues

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Article: Taxonomic recovery of the ant cricket Myrmecophilus albicinctus from M. americanus (Orthoptera, Myrmecophilidae).

Komatsu, Takashi / Maruyama, Munetoshi

ZooKeys

2016 , Issue 589, Page(s) 97–106

Abstract: Myrmecophilus americanus and Myrmecophilus albicinctus are typical myrmecophilous insects living inside ant nests. These species are ecologically important due to the obligate association with tramp ant species, including harmful invasive ant species. ... ...

Abstract	Myrmecophilus americanus and Myrmecophilus albicinctus are typical myrmecophilous insects living inside ant nests. These species are ecologically important due to the obligate association with tramp ant species, including harmful invasive ant species. However, the taxonomy of these "white-banded ant crickets" is quite confused owing to a scarcity of useful external morphological characteristics. Recently, Myrmecophilus albicinctus was synonymized with Myrmecophilus americanus regardless of the apparent host use difference. To clarify taxonomical relationship between Myrmecophilus albicinctus and Myrmecophilus albicinctus, we reexamined morphological characteristics of both species mainly in the viewpoint of anatomy. Observation of genitalia parts, together with a few external body parts, revealed that Myrmecophilus albicinctus showed different tendency from them of Myrmecophilus americanus. Therefore, we recover Myrmecophilus albicinctus as a distinct species on the basis of the morphology.
Language	English
Publishing date	2016-05-16
Publishing country	Bulgaria
Document type	Journal Article
ZDB-ID	2445640-8
ISSN	1313-2970 ; 1313-2989
ISSN (online)	1313-2970
ISSN	1313-2989
DOI	10.3897/zookeys.589.7739
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Article: Taxonomic recovery of the ant cricket Myrmecophilus albicinctus from M. americanus (Orthoptera, Myrmecophilidae)

Komatsu, Takashi / Maruyama, Munetoshi

ZooKeys. 2016 May 16, v. 589

2016

Abstract	Myrmecophilus americanus and Myrmecophilus albicinctus are typical myrmecophilous insects living inside ant nests. These species are ecologically important due to the obligate association with tramp ant species, including harmful invasive ant species. However, the taxonomy of these “white-banded ant crickets” is quite confused owing to a scarcity of useful external morphological characteristics. Recently, Myrmecophilus albicinctus was synonymized with Myrmecophilus americanus regardless of the apparent host use difference. To clarify taxonomical relationship between Myrmecophilus albicinctus and Myrmecophilus albicinctus, we reexamined morphological characteristics of both species mainly in the viewpoint of anatomy. Observation of genitalia parts, together with a few external body parts, revealed that Myrmecophilus albicinctus showed different tendency from them of Myrmecophilus americanus. Therefore, we recover Myrmecophilus albicinctus as a distinct species on the basis of the morphology.
Keywords	Orthoptera ; genitalia ; taxonomy
Language	English
Dates of publication	2016-0516
Size	p. 97-106.
Publishing place	Pensoft Publishers
Document type	Article
Note	NAL-light
ZDB-ID	2445640-8
ISSN	1313-2970 ; 1313-2989
ISSN (online)	1313-2970
ISSN	1313-2989
DOI	10.3897/zookeys.589.7739
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Article ; Online: Molecular characteristics of extended-spectrum β-lactamase-producing Escherichia coli in Japan: emergence of CTX-M-15-producing E. coli ST131.

Kuroda, Hitoshi / Yano, Hisakazu / Hirakata, Yoichi / Arai, Kazuaki / Endo, Shiro / Kanamori, Hajime / Yamamoto, Hiromi / Ichimura, Sadahiro / Ogawa, Miho / Shimojima, Masahiro / Komatsu, Mayumi / Jonai, Teruko / Itagaki, Sachiko / Nonomiya, Yuriko / Suwabe, Akira / Kaku, Mitsuo

Diagnostic microbiology and infectious disease

2012 Volume 74, Issue 2, Page(s) 201–203

Abstract: ... were studied. Among the 101 strains, 97 were positive for CTX-M, while 47 and two were positive for TEM ... and SHV, respectively. Sequencing revealed that CTX-M-14 was most common (49/101), followed by CTX-M ... 27 (22/101) and CTX-M-15 (8/101). Based on MLST data, seven of eight CTX-M-15 producers belonged ...

Abstract	We investigated the molecular characteristics of ESBL-producing Escherichia coli in Japan. A total of 101 clinical isolates of ESBL-positive E. coli collected in Japan between June 2008 and November 2009 were studied. Among the 101 strains, 97 were positive for CTX-M, while 47 and two were positive for TEM and SHV, respectively. Sequencing revealed that CTX-M-14 was most common (49/101), followed by CTX-M-27 (22/101) and CTX-M-15 (8/101). Based on MLST data, seven of eight CTX-M-15 producers belonged to ST131. This is the first report about clinical isolates of E. coli ST131 possessing CTX-M-15 in Japan.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Child, Preschool ; Cluster Analysis ; DNA, Bacterial/chemistry ; DNA, Bacterial/genetics ; Escherichia coli/classification ; Escherichia coli/enzymology ; Escherichia coli/genetics ; Escherichia coli/isolation & purification ; Escherichia coli Infections/epidemiology ; Escherichia coli Infections/microbiology ; Female ; Genotype ; Humans ; Infant ; Japan/epidemiology ; Male ; Middle Aged ; Molecular Epidemiology ; Multilocus Sequence Typing ; Sequence Analysis, DNA ; Young Adult ; beta-Lactamases/genetics ; beta-Lactamases/secretion
Chemical Substances	DNA, Bacterial ; beta-Lactamases (EC 3.5.2.6)
Language	English
Publishing date	2012-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	604920-5
ISSN	1879-0070 ; 0732-8893
ISSN (online)	1879-0070
ISSN	0732-8893
DOI	10.1016/j.diagmicrobio.2012.06.011
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Zs.A 1845: Show issues

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Article: Concentration of macrophage colony-stimulating factor (M-CSF) in bovine peripheral blood during pregnancy.

Oshima, Kazunaga / Yoshihara, Kazuhiro / Kojima, Takatoshi / Komatsu, Masanori / Yamamoto, Naoyuki

The Journal of veterinary medical science

2008 Volume 70, Issue 8, Page(s) 799–805

Abstract: Macrophage colony-stimulating factor (M-CSF) is a hemopoietic cytokine with a primary role ... in placental physiology. Gene expression of M-CSF in the bovine endometrium shows a temporal upward trend ... during early and mid pregnancy. This study determined the plasma M-CSF levels during pregnancy using ...

Abstract	Macrophage colony-stimulating factor (M-CSF) is a hemopoietic cytokine with a primary role in placental physiology. Gene expression of M-CSF in the bovine endometrium shows a temporal upward trend during early and mid pregnancy. This study determined the plasma M-CSF levels during pregnancy using ELISA. In experiment 1, to investigate the relationship between the concentration of M-CSF in peripheral blood and pregnancy, the plasma M-CSF levels were determined in 125 pregnant and 21 non-pregnant Japanese Black cows. The pregnant animals were divided into nine groups based on the month of pregnancy. An ELISA for bovine M-CSF established previously was used according to the authors' instructions. In experiment 2, the plasma M-CSF level was determined to investigate the temporal changes in its concentration in the peripheral blood during pregnancy. In experiment 1, the plasma M-CSF level varied from month to month during pregnancy; the mean level in the first-month of pregnancy was significantly higher than those in the third and last months of pregnancy and non-pregnancy (P<0.05). In experiment 2, the plasma M-CSF level varied with the day of pregnancy (P<0.05). The mean level of plasma M-CSF decreased gradually until 6 weeks of pregnancy; it appeared to increase during weeks 7-9, then varied with several small peaks until 27 weeks of pregnancy and finally decreased gradually until parturition. These results suggest that the plasma M-CSF level may be related to changes in the uterus and placenta as pregnancy progresses.
MeSH term(s)	Animals ; Cattle ; Estrus/physiology ; Female ; Macrophage Colony-Stimulating Factor/blood ; Macrophage Colony-Stimulating Factor/metabolism ; Placenta/physiology ; Pregnancy ; Pregnancy, Animal/physiology ; Reference Values ; Uterus/physiology
Chemical Substances	Macrophage Colony-Stimulating Factor (81627-83-0)
Language	English
Publishing date	2008-09-01
Publishing country	Japan
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1071753-5
ISSN	1347-7439 ; 0916-7250
ISSN (online)	1347-7439
ISSN	0916-7250
DOI	10.1292/jvms.70.799
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Zs.B 579: Show issues

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Article ; Online: Occurrence and potential activity of denitrifiers and methanogens in groundwater at 140 m depth in Pliocene diatomaceous mudstone of northern Japan.

Katsuyama, Chie / Nashimoto, Hiroaki / Nagaosa, Kazuyo / Ishibashi, Tomotaka / Furuta, Kazuki / Kinoshita, Takeshi / Yoshikawa, Hideki / Aoki, Kazuhiro / Asano, Takahiro / Sasaki, Yoshito / Sohrin, Rumi / Komatsu, Daisuke D / Tsunogai, Urumu / Kimura, Hiroyuki / Suwa, Yuichi / Kato, Kenji

FEMS microbiology ecology

2013 Volume 86, Issue 3, Page(s) 532–543

Abstract: ... the denitrification and methanogenesis in anoxic groundwater at a depth of 140 m in two boreholes drilled ... evident during the incubations. The groundwater at 140 m depth did not contain oxygen, had an Eh ranging ...

Abstract	Anaerobic microbial activity has a major influence on the subsurface environment. We investigated the denitrification and methanogenesis in anoxic groundwater at a depth of 140 m in two boreholes drilled in a sedimentary geological setting, where the redox potential fluctuated. The average maximum potential denitrification rates, measured under anaerobic conditions in the two boreholes using an (15) N tracer, were 0.060 and 0.085 nmol (30) N2 mL(-1) h(-1) . The deduced NirS amino acid sequences obtained from in situ samples were similar to those of isolates belonging to the α-, β-, and γ-Proteobacteria, and the Firmicutes (72-100% similarity). Based on the nirS gene, the same operational taxonomic unit dominated incubated samples from each borehole. Methanogenesis candidates were detected by 16S rRNA gene analysis, but no sequence was detected using primers for the functional methanogenesis gene mcrA. Although the stable isotope signatures suggested that some of the dissolved methane was of biogenic origin, no potential for methane production was evident during the incubations. The groundwater at 140 m depth did not contain oxygen, had an Eh ranging from -144 to 6.8 mV, and was found to be a potential field for denitrification.
MeSH term(s)	Archaea/classification ; Archaea/genetics ; Archaea/isolation & purification ; Archaea/metabolism ; Denitrification ; Genes, rRNA ; Geologic Sediments/microbiology ; Groundwater/microbiology ; Japan ; Methane/metabolism ; Molecular Sequence Data ; Phylogeny ; Proteobacteria/classification ; Proteobacteria/genetics ; Proteobacteria/isolation & purification ; Proteobacteria/metabolism ; RNA, Ribosomal, 16S/genetics
Chemical Substances	RNA, Ribosomal, 16S ; Methane (OP0UW79H66)
Language	English
Publishing date	2013-12
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	283722-5
ISSN	1574-6941 ; 0168-6496
ISSN (online)	1574-6941
ISSN	0168-6496
DOI	10.1111/1574-6941.12179
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Zs.A 2967: Show issues

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Article: Structures of stemona-amine B and stemona-lactams M–R

Hitotsuyanagi, Yukio / Fukaya, Haruhiko / Takeda, Erika / Matsuda, Shoko / Saishu, Yuka / Zhu, Shu / Komatsu, Katsuko / Takeya, Koichi

Tetrahedron. 2013 July 29, v. 69, no. 30

2013

Abstract: Seven new alkaloids, stemona-amine B and stemona-lactams M–R, were isolated from the roots ...

Abstract	Seven new alkaloids, stemona-amine B and stemona-lactams M–R, were isolated from the roots of Stemona tuberosa. Their structures were determined by interpretation of spectroscopic data, chemical behavior, and X-ray crystallographic data.
Keywords	Stemona tuberosa ; X-ray diffraction ; alkaloids ; chemical reactions ; chemical structure ; roots ; spectroscopy
Language	English
Dates of publication	2013-0729
Size	p. 6297-6304.
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	204285-x
ISSN	1464-5416 ; 0040-4020 ; 0563-2064
ISSN (online)	1464-5416
ISSN	0040-4020 ; 0563-2064
DOI	10.1016/j.tet.2013.04.136
Database	NAL-Catalogue (AGRICOLA)

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Article: [Outcome of treatment with surgical resection of the remaining tumor after modified M-VAC treatment for advanced urothelial carcinoma].

Narita, Shintaro / Nakano, Masahiro / Matsuzaki, Masato / Watanabe, Jyunichi / Morikawa, Hiroshi / Murata, Hirokatsu / Oda, Hiroyuki / Komatsu, Hideki

Hinyokika kiyo. Acta urologica Japonica

2005 Volume 51, Issue 3, Page(s) 155–158

Abstract: ... modified M-VAC (methotrexate, vinblastine, doxorubicin and cisplatin) (m-M-VAC) treatment for locally ... advanced or metastatic urothelial carcinoma. In m-M-VAC therapy, methotrexate and vinblastine on 15 and 22 ... days were omitted from the classical M-VAC to avoid the discontinuation and the dose reduction, and ...

Abstract	We retrospectively evaluated the effect of the surgical resection of the remaining tumor after modified M-VAC (methotrexate, vinblastine, doxorubicin and cisplatin) (m-M-VAC) treatment for locally advanced or metastatic urothelial carcinoma. In m-M-VAC therapy, methotrexate and vinblastine on 15 and 22 days were omitted from the classical M-VAC to avoid the discontinuation and the dose reduction, and duration of 1 course was shortened to 21 days from 28 days of the classical M-VAC. Seven patients with locally invasive or metastatic carcinoma of the renal pelvis, ureter, and bladder, 6 males and 1 female, with a median age 64.1 years, ranging from 49 to 77 years received m-M-VAC chemotherapy without severe side effects. In all patients, the residual viable carcinoma was completely resected and they achieved complete remission. The median survival time was 20 months (range, 7 to 61). Five of these 7 patients were still alive. Two patients had no recurrence and achieved long-term survival (survival duration; 61 and 39 months). Although further studies and long-term follow up are required, these results suggest that patients who present with locally advanced or metastatic urothelial carcinoma may benefit from surgical resection after m-M-VAC.
MeSH term(s)	Aged ; Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Carcinoma, Transitional Cell/drug therapy ; Carcinoma, Transitional Cell/surgery ; Cisplatin/administration & dosage ; Combined Modality Therapy ; Doxorubicin/administration & dosage ; Drug Administration Schedule ; Female ; Humans ; Lymph Node Excision ; Male ; Methotrexate/administration & dosage ; Middle Aged ; Treatment Outcome ; Urologic Neoplasms/drug therapy ; Urologic Neoplasms/surgery ; Vinblastine/administration & dosage
Chemical Substances	Vinblastine (5V9KLZ54CY) ; Doxorubicin (80168379AG) ; Cisplatin (Q20Q21Q62J) ; Methotrexate (YL5FZ2Y5U1)
Language	Japanese
Publishing date	2005-03
Publishing country	Japan
Document type	English Abstract ; Journal Article ; Review
ZDB-ID	604331-8
ISSN	0018-1994
ISSN	0018-1994
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Zs.A 411: Show issues

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Article: [Clinical study of modified M-VAC therapy with one 21-day cycle for advanced urothelial cancer].

Nakanishi, Shinichi / Matsuzaki, Masato / Morikawa, Hiroshi / Nakano, Masahiro / Komatsu, Hideki

Hinyokika kiyo. Acta urologica Japonica

2004 Volume 50, Issue 10, Page(s) 667–671

Abstract: Although M-VAC therapy is a standard chemotherapy for advanced transitional cell carcinoma ... the toxicity we modified the treatment schedule of M-VAC treatment. The dosages of this simplified M-VAC ... with this simplified M-VAC therapy without dose modification or delay. The median number of cycles was 4. Neutropenia ...

Abstract	Although M-VAC therapy is a standard chemotherapy for advanced transitional cell carcinoma, the treatment schedule has to be delayed or cancelled in many patients because of the toxicity. To reduce the toxicity we modified the treatment schedule of M-VAC treatment. The dosages of this simplified M-VAC therapy were 30 mg/m2 methotrexate (on day 1), 3 mg/m2 vinblastine (on day 2), 30 mg/m2 doxorubicin (on day 2) and 70 mg/m2 cisplatin (on day 2), with courses repeated every 21 days for four cycles as a principle. Seventeen patients with histologically proven advanced transitional cell carcinoma were treated with this simplified M-VAC therapy without dose modification or delay. The median number of cycles was 4. Neutropenia, anemia and thrombopenia (grade 4) was observed in 2, 1 and 2 patients respectively, but no drug-related deaths were observed. Complete response and partial response were achieved in 2 (12%) and 10 (59%) patients respectively. Of 2 complete responders one patient was alive without evidence of disease at 12 months and another patient died of the disease at 42 months. Of 10 partial responders 6 patients underwent the additional surgical resection of residual tumors. Of these 6 patients 3 patients are alive without evidence of disease at 6, 30 and 31 months. The remaining 3 developed recurrence and 2 died of the disease at 13 and 29 months. Five non-responders died of the disease at 5 months after the start of the therapy. Response rate of simplified M-VAC therapy was excellent and treatment duration was short. However, relapses were commonly observed as well as the original M-VAC treatment.
MeSH term(s)	Aged ; Anemia/chemically induced ; Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Carcinoma, Transitional Cell/drug therapy ; Carcinoma, Transitional Cell/secondary ; Cisplatin/administration & dosage ; Cisplatin/adverse effects ; Doxorubicin/administration & dosage ; Doxorubicin/adverse effects ; Drug Administration Schedule ; Female ; Humans ; Lymph Nodes/pathology ; Lymphatic Metastasis ; Male ; Methotrexate/administration & dosage ; Methotrexate/adverse effects ; Middle Aged ; Neutropenia/chemically induced ; Thrombocytopenia/chemically induced ; Urologic Neoplasms/drug therapy ; Urologic Neoplasms/pathology ; Vinblastine/administration & dosage ; Vinblastine/adverse effects
Chemical Substances	Vinblastine (5V9KLZ54CY) ; Doxorubicin (80168379AG) ; Cisplatin (Q20Q21Q62J) ; Methotrexate (YL5FZ2Y5U1)
Language	Japanese
Publishing date	2004-10
Publishing country	Japan
Document type	English Abstract ; Journal Article
ZDB-ID	604331-8
ISSN	0018-1994
ISSN	0018-1994
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Zs.A 411: Show issues

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Article ; Online: Dissection and identification of regions required to form pseudoparticles by the interaction between the nucleocapsid (N) and membrane (M) proteins of SARS coronavirus.

Hatakeyama, Seisuke / Matsuoka, Yusuke / Ueshiba, Hidehiro / Komatsu, Nobukazu / Itoh, Kyogo / Shichijo, Shigeki / Kanai, Takao / Fukushi, Masaya / Ishida, Isao / Kirikae, Teruo / Sasazuki, Takehiko / Miyoshi-Akiyama, Tohru

Virology

2008 Volume 380, Issue 1, Page(s) 99–108

Abstract: When expressed in mammalian cells, the nucleocapsid (N) and membrane (M) proteins ... mutants and M in HEK293 cells. Using a peptide library derived from N, we found that amino acids 101-115 ... constituted a novel binding site for M. We examined the ability of N mutants to interact with M and form ...

Abstract	When expressed in mammalian cells, the nucleocapsid (N) and membrane (M) proteins of the severe acute respiratory syndrome coronavirus (SARS-CoV) are sufficient to form pseudoparticles. To identify region(s) of the N molecule required for pseudoparticle formation, we performed biochemical analysis of the interaction of N mutants and M in HEK293 cells. Using a peptide library derived from N, we found that amino acids 101-115 constituted a novel binding site for M. We examined the ability of N mutants to interact with M and form pseudoparticles, and our observations indicated that M bound to NDelta(101-115), N1-150, N151-300, and N301-422, but not to N1-150Delta(101-115). However, pseudoparticles were formed when NDelta(101-115) or N301-422, but not N1-150 or N151-300, were expressed with M in HEK293 cells. These results indicated that the minimum portion of N required for the interaction with M and pseudoparticle formation consists of amino acids 301-422.
MeSH term(s)	Cell Line ; Coronavirus M Proteins ; Coronavirus Nucleocapsid Proteins ; Nucleocapsid/genetics ; Nucleocapsid/metabolism ; Nucleocapsid Proteins/chemistry ; Nucleocapsid Proteins/genetics ; Nucleocapsid Proteins/metabolism ; RNA, Viral/chemistry ; RNA, Viral/genetics ; SARS Virus/chemistry ; Viral Matrix Proteins/genetics ; Viral Matrix Proteins/metabolism
Chemical Substances	Coronavirus M Proteins ; Coronavirus Nucleocapsid Proteins ; M protein, SARS-CoV ; Nucleocapsid Proteins ; RNA, Viral ; Viral Matrix Proteins
Keywords	covid19
Language	English
Publishing date	2008-08-13
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	200425-2
ISSN	1096-0341 ; 0042-6822
ISSN (online)	1096-0341
ISSN	0042-6822
DOI	10.1016/j.virol.2008.07.012
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