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  1. Article ; Online: Response to the Comments by Dr. Endrikat et al. on the article "Tissue gadolinium deposition in hepatorenally impaired rats exposed to Gd-EOB-DTPA: evaluation with inductively coupled plasma mass spectrometry (ICP-MS)" by Tomohiro Sato, Tsutomu Tamada, Shigeru Watanabe et al. DOI 10.1007/s11547-014-0492-y.

    Sato, Tomohiro

    La Radiologia medica

    2016  Volume 121, Issue 3, Page(s) 240–241

    MeSH term(s) Animals ; Contrast Media/metabolism ; Gadolinium/analysis ; Gadolinium DTPA/metabolism ; Kidney Diseases/metabolism ; Liver Diseases/metabolism ; Male
    Chemical Substances Contrast Media ; Gadolinium (AU0V1LM3JT) ; Gadolinium DTPA (K2I13DR72L)
    Language English
    Publishing date 2016-03
    Publishing country Italy
    Document type Comment ; Journal Article
    ZDB-ID 205751-7
    ISSN 1826-6983 ; 0033-8362
    ISSN (online) 1826-6983
    ISSN 0033-8362
    DOI 10.1007/s11547-015-0592-3
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  2. Article ; Online: Contribution of the retrosplenial cortex to route selection in a complex maze.

    Hayashi, Tomohiro / Sato, Nobuya

    Neuroscience research

    2023  Volume 202, Page(s) 52–59

    Abstract: The retrosplenial cortex (RSC) is a region involved in navigation. In this study, we investigated the role of the RSC in navigation in a large-scale environment where the destination is not visible from the current location. We used a large maze where ... ...

    Abstract The retrosplenial cortex (RSC) is a region involved in navigation. In this study, we investigated the role of the RSC in navigation in a large-scale environment where the destination is not visible from the current location. We used a large maze where the routes could be freely designed by inserting and removing plates. In Experiment 1, rats learned a specific route in the maze and then were tested with a shortcut route in addition to the learned route. The rats with RSC lesions utilized the shortcut faster than those in the control group. In Experiment 2, rats were initially trained to follow a specific route, and subsequently, we tested the effects of a small change in the environment on their route-following behavior. In the test, the rats with RSC lesions demonstrated more errors than those in the control group. This suggests that lesions in the RSC make navigation to a goal unstable. These findings suggest that the RSC may be involved in the ability to perform appropriate behavior at a segment on a learned route in a large-scale environment, which drives habitually following the learned route.
    MeSH term(s) Animals ; Maze Learning/physiology ; Male ; Rats ; Spatial Navigation/physiology ; Cerebral Cortex/physiology ; Gyrus Cinguli/physiology
    Language English
    Publishing date 2023-12-01
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 605842-5
    ISSN 1872-8111 ; 0168-0102 ; 0921-8696
    ISSN (online) 1872-8111
    ISSN 0168-0102 ; 0921-8696
    DOI 10.1016/j.neures.2023.11.011
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  3. Article ; Online: Sec16 and Sed4 interdependently function as interaction and localization partners at ER exit sites.

    Yorimitsu, Tomohiro / Sato, Ken

    Journal of cell science

    2023  Volume 136, Issue 9

    Abstract: COPII proteins assemble at ER exit sites (ERES) to form transport carriers. The initiation of COPII assembly in the yeast Saccharomyces cerevisiae is triggered by the ER membrane protein Sec12. Sec16, which plays a critical role in COPII organization, ... ...

    Abstract COPII proteins assemble at ER exit sites (ERES) to form transport carriers. The initiation of COPII assembly in the yeast Saccharomyces cerevisiae is triggered by the ER membrane protein Sec12. Sec16, which plays a critical role in COPII organization, localizes to ERES independently of Sec12. However, the mechanism underlying Sec16 localization is poorly understood. Here, we show that a Sec12 homolog, Sed4, is concentrated at ERES and mediates ERES localization of Sec16. We found that the interaction between Sec16 and Sed4 ensures their correct localization to ERES. Loss of the interaction with Sec16 leads to redistribution of Sed4 from the ERES specifically to high-curvature ER areas, such as the tubules and edges of the sheets. The luminal domain of Sed4 mediates this distribution, which is required for Sed4, but not for Sec16, to be concentrated at ERES. We further show that the luminal domain and its O-mannosylation are involved in the self-interaction of Sed4. Our findings provide insight into how Sec16 and Sed4 function interdependently at ERES.
    MeSH term(s) Endoplasmic Reticulum ; Glycosylation ; Membrane Proteins ; Saccharomyces cerevisiae ; Saccharomyces cerevisiae Proteins/genetics
    Chemical Substances Membrane Proteins ; SEC16 protein, S cerevisiae ; Saccharomyces cerevisiae Proteins
    Language English
    Publishing date 2023-05-09
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2993-2
    ISSN 1477-9137 ; 0021-9533
    ISSN (online) 1477-9137
    ISSN 0021-9533
    DOI 10.1242/jcs.261094
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  4. Article ; Online: A novel 2.4-kb PHKA2 deletion in a boy with glycogen storage disease type IXa.

    Sato, Takeshi / Ichihashi, Yosuke / Sugie, Hideo / Ishii, Tomohiro / Hasegawa, Tomonobu

    Congenital anomalies

    2024  Volume 64, Issue 2, Page(s) 63–65

    MeSH term(s) Humans ; Male ; Glycogen Storage Disease/diagnosis ; Glycogen Storage Disease/genetics ; Liver ; Mutation ; Phosphorylase Kinase/genetics
    Chemical Substances PHKA2 protein, human (EC 2.7.1.19) ; Phosphorylase Kinase (EC 2.7.1.19)
    Language English
    Publishing date 2024-02-15
    Publishing country Australia
    Document type Case Reports ; Journal Article
    ZDB-ID 228664-6
    ISSN 1741-4520 ; 0037-2285 ; 0914-3505
    ISSN (online) 1741-4520
    ISSN 0037-2285 ; 0914-3505
    DOI 10.1111/cga.12555
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  5. Article ; Online: Comparison design and evaluation power in cohort and self-controlled case series designs for post-authorization vaccine safety studies.

    Sato, Shuntaro / Kawazoe, Yurika / Katsuta, Tomohiro / Fukuda, Haruhisa

    PeerJ

    2024  Volume 12, Page(s) e16780

    Abstract: Background: Post-authorization safety studies (PASSs) of vaccines are important. PASSs enable the evaluation of association between vaccination and adverse events following immunization through common study designs. Clinical trials during vaccine ... ...

    Abstract Background: Post-authorization safety studies (PASSs) of vaccines are important. PASSs enable the evaluation of association between vaccination and adverse events following immunization through common study designs. Clinical trials during vaccine development typically include a few thousand to 10,000 participants while a PASS might aim to detect a few adverse events per 100,000 vaccine recipients. While all available data may be utilized, prior consideration of power analyses are nonetheless crucial for interpretation in cases where statistically significant differences are not found.
    Methods: This research primarily examined cohort study design and self-controlled case series (SCCS) design, estimating the power of a PASS under plausible conditions.
    Results: Both the cohort study and SCCS designs necessitated large sample sizes or high event counts to guarantee adequate power. The SCCS design is particularly suited to evaluating rare adverse events. However, extremely rare events may not yield sufficient occurrences, thereby resulting in low power. Although the SCCS design can more efficiently control for time-invariant confounding in principle, it solely estimates relative measures. A cohort study design might be preferred if confounding can be adequately managed as it also estimates absolute measures. It may be an easy decision to use all the data at hand for either design. We found it necessary to estimate the sample size and number of events to be used in the study based on
    MeSH term(s) Humans ; Cohort Studies ; Immunization/adverse effects ; Research Design ; Vaccination/adverse effects
    Language English
    Publishing date 2024-01-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2703241-3
    ISSN 2167-8359 ; 2167-8359
    ISSN (online) 2167-8359
    ISSN 2167-8359
    DOI 10.7717/peerj.16780
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  6. Article ; Online: Retraction notice to "Risk factors for hip fracture among elderly patients with Alzheimer's disease" [Journal of the Neurological Sciences 223 (2004), 107-112].

    Sato, Yoshihiro / Kanoko, Tomohiro / Satoh, Kei / Iwamoto, Jun

    Journal of the neurological sciences

    2023  Volume 456, Page(s) 122823

    Language English
    Publishing date 2023-12-02
    Publishing country Netherlands
    Document type Journal Article ; Retraction of Publication
    ZDB-ID 80160-4
    ISSN 1878-5883 ; 0022-510X ; 0374-8642
    ISSN (online) 1878-5883
    ISSN 0022-510X ; 0374-8642
    DOI 10.1016/j.jns.2023.122823
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  7. Article: Adrenal crisis during a trip in a young child with septo-optic dysplasia.

    Takahashi, Miho / Sato, Takeshi / Nakano, Satsuki / Hamada, Junpei / Ishii, Tomohiro / Hasegawa, Tomonobu

    Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology

    2024  Volume 33, Issue 2, Page(s) 101–103

    Language English
    Publishing date 2024-01-28
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2079760-6
    ISSN 0918-5739
    ISSN 0918-5739
    DOI 10.1297/cpe.2023-0067
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  8. Article ; Online: Novel automated atrial pacemapping technique based on intracardiac pattern matching to identify the location of ectopic atrial activity.

    Nishiuchi, Suguru / Sato, Tomohiro / Yamagami, Shintaro / Kondo, Hirokazu / Tamura, Toshihiro

    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing

    2024  

    Abstract: Atrial ectopy from the pulmonary veins and non-pulmonary vein foci can trigger atrial fibrillation. In addition, the elimination of atrial ectopy is important to prevent recurrence. The intracardiac pattern matching technique has been reported as a ... ...

    Abstract Atrial ectopy from the pulmonary veins and non-pulmonary vein foci can trigger atrial fibrillation. In addition, the elimination of atrial ectopy is important to prevent recurrence. The intracardiac pattern matching technique has been reported as a useful method to manually visualize the location of triggers regardless of their frequency. We combined the original intracardiac pattern matching method with the automapping setting of CARTO CONFIDENCE and discovered the automated atrial pacemapping technique. We report two cases in which this technique was used to eliminate the atrial triggers. This technique achieved a time reduction and high-resolution mapping.
    Language English
    Publishing date 2024-04-23
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1329179-8
    ISSN 1572-8595 ; 1383-875X
    ISSN (online) 1572-8595
    ISSN 1383-875X
    DOI 10.1007/s10840-024-01812-z
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  9. Article ; Online: Intermediate conductance Ca

    Numata, Tomohiro / Sato-Numata, Kaori / Yoshino, Masami

    Frontiers in insect science

    2023  Volume 2, Page(s) 1100671

    Abstract: Cooperative gating of localized ion channels ranges from fine-tuning excitation-contraction coupling in muscle cells to controlling pace-making activity in the heart. Membrane deformation resulting from muscle contraction activates stretch-activated (SA) ...

    Abstract Cooperative gating of localized ion channels ranges from fine-tuning excitation-contraction coupling in muscle cells to controlling pace-making activity in the heart. Membrane deformation resulting from muscle contraction activates stretch-activated (SA) cation channels. The subsequent Ca
    Language English
    Publishing date 2023-01-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 3123819-1
    ISSN 2673-8600 ; 2673-8600
    ISSN (online) 2673-8600
    ISSN 2673-8600
    DOI 10.3389/finsc.2022.1100671
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  10. Article ; Online: Letter to the Editor regarding "Serum steroid metabolite profiling by LC-MS/MS in two phenotypic male patients with HSD17B3 deficiency: Implications for hormonal diagnosis".

    Sato, Takeshi / Nakano, Satsuki / Honda, Misa / Narumi, Satoshi / Ishii, Tomohiro / Hasegawa, Tomonobu

    The Journal of steroid biochemistry and molecular biology

    2024  Volume 239, Page(s) 106484

    MeSH term(s) Humans ; Male ; Liquid Chromatography-Mass Spectrometry ; Chromatography, Liquid ; Tandem Mass Spectrometry ; Steroids ; Dehydroepiandrosterone
    Chemical Substances Steroids ; Dehydroepiandrosterone (459AG36T1B)
    Language English
    Publishing date 2024-02-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 1049188-0
    ISSN 1879-1220 ; 0960-0760
    ISSN (online) 1879-1220
    ISSN 0960-0760
    DOI 10.1016/j.jsbmb.2024.106484
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