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Book ; Thesis: Einfluss der Immunsuppression auf die chirurgische Therapie bei Morbus Crohn

Gund, Madline Priska

2013

Author's details	Madline Priska Gund
Language	German
Size	48 Bl.
Publishing country	Germany
Document type	Book ; Thesis
Thesis / German Habilitation thesis	Freiburg (Breisgau), Univ., Diss., 2014
HBZ-ID	HT018684128
Database	Catalogue ZB MED Medicine, Health

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Article: L. reuteri

Thierbach, René / Eigenmann, Andreas / Naim, Jusef / Hannig, Matthias / Rupf, Stefan / Gund, Madline P

Microorganisms

2024 Volume 12, Issue 4

Abstract: Aim: The purpose of this study was to investigate whether a clinical effect of : Materials and methods: 28 patients with stage III and IV periodontitis undergoing periodontal follow-up were randomly divided into two groups receiving a lozenge ... ...

Abstract	Aim: The purpose of this study was to investigate whether a clinical effect of Materials and methods: 28 patients with stage III and IV periodontitis undergoing periodontal follow-up were randomly divided into two groups receiving a lozenge containing Results: The results sed a different effect of Conclusions: The oral administration of one lozenge per day for 3 months with
Language	English
Publishing date	2024-03-25
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2720891-6
ISSN	2076-2607
ISSN	2076-2607
DOI	10.3390/microorganisms12040648
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Article ; Online: Einführung des Fachs „Berufsfelderkundung“ für Studierende der Zahnmedizin an der Universität des Saarlandes.

Rupf, Stefan / Gund, Madline / Strähle, Ulf / Naim, Jusef / Hannig, Matthias

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz

2023 Volume 66, Issue 12, Page(s) 1328–1335

Abstract: The new dental licensing regulations (ZApprO) have been in effect since the 2021/2022 winter semester and stipulate that a "professional field exploration course" be offered in the dentistry degree program. At Saarland University, the course consists of ... ...

Title translation	Introduction of "professional field exploration" for Saarland University dentistry students.
Abstract	The new dental licensing regulations (ZApprO) have been in effect since the 2021/2022 winter semester and stipulate that a "professional field exploration course" be offered in the dentistry degree program. At Saarland University, the course consists of five parts: (I) introduction, (II) practicum, (III) reflection report, (IV) symposium, and (V) evaluation. The practicum is designed to provide students with earlier exposure to clinical reality, give them more confidence in dealing with patients, motivate them, and teach them about the professional role in the healthcare profession. In addition, the reflection report and symposium will initiate the development of scientific competencies. The evaluation, together with the evaluation of the reflection reports, serves to verify the success of the introduction of the course. The purpose of this paper is to describe the new course and to present the results of the result of the evaluation of the two courses in 2021 and 2022.
MeSH term(s)	Humans ; Universities ; Curriculum ; Germany ; Students ; Dentistry
Language	German
Publishing date	2023-11-07
Publishing country	Germany
Document type	English Abstract ; Journal Article
ZDB-ID	1461973-8
ISSN	1437-1588 ; 1436-9990
ISSN (online)	1437-1588
ISSN	1436-9990
DOI	10.1007/s00103-023-03790-5
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Article ; Online: Detection of viable oral bacteria of the patient on the surgical mask of dentists.

Gund, Madline Priska / Naim, Jusef / Lang, Janina / Hannig, Matthias / Gärtner, Barbara / Halfmann, Alexander / Boros, Gabor / Rupf, Stefan

BDJ open

2024 Volume 10, Issue 1, Page(s) 4

Abstract: Introduction and aim: Bioaerosols contaminate the personal protective equipment (PPE), especially masks. The PPE harbors microorganisms from various sources. However, no previous studies have investigated the specific sources of bacteria found on used ... ...

Abstract	Introduction and aim: Bioaerosols contaminate the personal protective equipment (PPE), especially masks. The PPE harbors microorganisms from various sources. However, no previous studies have investigated the specific sources of bacteria found on used masks and their correlation with those from the treated patient. Setting, design, material and methods: Intraoral samples from the patient were collected prior to dental aerosol-producing treatments using a nylon flock fiber swab. After treatment, the practitioner's mask was imprinted onto agar plates. Main outcome methods: Following cultivation, colony forming units were counted and identified using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). After the samples were analyzed, the intraoral samples as well as the mask samples were assessed for the presence of identical species, which were subsequently quantified. Results: 126 treatments were included. One species match occurred most frequently (26.2%), followed by two (11.9%%) and three or more (3.97%). In the intraoral samples, Neisseria subflava occurred most often, within mask samples Staphylococcus epidermidis were detected most. Staphylococcus aureus could be cultivated three times more often in intraoral samples than on the mask. Discussion and conclusion: Oral microorganisms originating from the patient's oral cavity can be found on the outside of masks. When using PPE during treatments, it should therefore always be in mind that potentially pathogenic microorganisms may land on the mask becoming a source of for itself.
Language	English
Publishing date	2024-01-16
Publishing country	England
Document type	Journal Article
ISSN	2056-807X
ISSN (online)	2056-807X
DOI	10.1038/s41405-023-00182-4
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Article ; Online: Dental aerosol-producing treatments: Comparison of contamination patterns of face shields and surgical masks.

Gund, Madline P / Naim, Jusef / Bayhan, Halil Muhammed / Hannig, Matthias / Gärtner, Barbara / Halfmann, Alexander / Boros, Gabor / Rupf, Stefan

Journal of occupational and environmental hygiene

2024 Volume 21, Issue 2, Page(s) 126–135

Abstract: During the COVID-19 pandemic, dental face shields were recommended to protect the eyes. This study aimed to examine to what extent face shield and mask contamination differ when a pre-procedural mouth rinsing with Chlorhexidine (CHX) is conducted before ... ...

Abstract	During the COVID-19 pandemic, dental face shields were recommended to protect the eyes. This study aimed to examine to what extent face shield and mask contamination differ when a pre-procedural mouth rinsing with Chlorhexidine (CHX) is conducted before treatment. In this prospective, randomized study, three groups of subjects were formed (rinsing with 0.1% CHX, water, or no rinsing (control) before aerosol-producing treatments). After each of the 301 treatments, the practitioner's face shield was swabbed with eSwab and the mask was brought into contact with agar plates. Sampling was done from the exterior surface only. Samples were cultured for 48 h at 35 °C under aerobic and anaerobic conditions. Bacteria were classified by phenotypic characteristics, biochemical test methods, and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). Colony-forming units were counted and mean values were compared (WSR, H-test, U-test,
MeSH term(s)	Humans ; Pandemics ; Respiratory Aerosols and Droplets ; Chlorhexidine/pharmacology ; Protective Devices ; Bacteria ; Water/pharmacology
Chemical Substances	Chlorhexidine (R4KO0DY52L) ; Water (059QF0KO0R)
Language	English
Publishing date	2024-02-23
Publishing country	England
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	2131820-7
ISSN	1545-9632 ; 1545-9624
ISSN (online)	1545-9632
ISSN	1545-9624
DOI	10.1080/15459624.2023.2285363
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Article: Cold Atmospheric Plasma Improves the Colonization of Titanium with Primary Human Osteoblasts: An In Vitro Study.

Gund, Madline P / Naim, Jusef / Lehmann, Antje / Hannig, Matthias / Lange, Markus / Schindler, Axel / Rupf, Stefan

Biomedicines

2024 Volume 12, Issue 3

Abstract: Several studies have shown that cold atmospheric plasma (CAP) treatment can favourably modify titanium surfaces to promote osteoblast colonization. The aim of this study was to investigate the initial attachment of primary human osteoblasts to plasma- ... ...

Abstract	Several studies have shown that cold atmospheric plasma (CAP) treatment can favourably modify titanium surfaces to promote osteoblast colonization. The aim of this study was to investigate the initial attachment of primary human osteoblasts to plasma-treated titanium. Micro-structured titanium discs were treated with cold atmospheric plasma followed by the application of primary human osteoblasts. The microwave plasma source used in this study uses helium as a carrier gas and was developed at the Leibniz Institute for Surface Modification in Leipzig, Germany. Primary human osteoblasts were analyzed by fluorescence and cell biological tests (alkaline phosphatase activity and cell proliferation using WST-1 assay). The tests were performed after 4, 12, and 24 h and showed statistically significant increased levels of cell activity after plasma treatment. The results of this study indicate that plasma treatment improves the initial attachment of primary human osteoblasts to titanium. For the first time, the positive effect of cold atmospheric plasma treatment of micro-structured titanium on the initial colonization with primary human osteoblasts has been demonstrated. Overall, this study demonstrates the excellent biocompatibility of micro-structured titanium. The results of this study support efforts to use cold atmospheric plasmas in implantology, both for preimplantation conditioning and for regeneration of lost attachment due to peri-implantitis.
Language	English
Publishing date	2024-03-18
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2720867-9
ISSN	2227-9059
ISSN	2227-9059
DOI	10.3390/biomedicines12030673
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Article ; Online: Apical periodontitis after intense bruxism.

Gund, Madline P / Wrbas, Karl-Thomas / Hannig, Matthias / Rupf, Stefan

BMC oral health

2022 Volume 22, Issue 1, Page(s) 91

Abstract: Background: Bruxism is known to cause masticatory muscle pain, temporomandibular joint pain, headaches, mechanical tooth wear, prosthodontic complications and cracked teeth. Less known to the practitioner, and described only experimentally in literature, ...

Abstract	Background: Bruxism is known to cause masticatory muscle pain, temporomandibular joint pain, headaches, mechanical tooth wear, prosthodontic complications and cracked teeth. Less known to the practitioner, and described only experimentally in literature, is that bruxism can also damage the pulp. To our knowledge, this is the first known clinical case of a patient developing apical periodontitis due to bruxism. Case presentation: This article presents the case and successful treatment of a 28-year-old healthy male patient with apical periodontitis on teeth 36 and 46 requiring root canal treatment after an intense phase of bruxism. Due to an unclear diagnosis, treatment had been delayed. Conclusions: Incomprehensible tooth pain can be the result of bruxism. Practitioners need to be informed that intense bruxism can possibly lead to apical periodontitis. It is important, therefore, that a thorough anamnesis is collected and taken into account during diagnostics.
MeSH term(s)	Adult ; Bruxism/complications ; Bruxism/therapy ; Humans ; Male ; Masticatory Muscles ; Pain/complications ; Periapical Periodontitis/complications ; Periapical Periodontitis/therapy ; Root Canal Therapy/adverse effects
Language	English
Publishing date	2022-03-24
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	2091511-1
ISSN	1472-6831 ; 1472-6831
ISSN (online)	1472-6831
ISSN	1472-6831
DOI	10.1186/s12903-022-02123-3
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Article ; Online: The impact of general medical health status, demographical, and patient-specific variables on need for dental treatment of children and adolescents under general anesthesia.

Kries, Tilman / Rupf, Stefan / Hannig, Matthias / Naim, Jusef / Gund, Madline P

Clinical oral investigations

2023 Volume 27, Issue 8, Page(s) 4245–4257

Abstract: Objectives: Aim of this retrospective study was to examine the influence of general medical, demographical, and other patient-specific factors on the need for dental treatment under general anesthesia in children and adolescents at Saarland University ... ...

Abstract	Objectives: Aim of this retrospective study was to examine the influence of general medical, demographical, and other patient-specific factors on the need for dental treatment under general anesthesia in children and adolescents at Saarland University Hospital. For assessment of the clinical treatment need, a mixed dt/DT (decayed teeth) was introduced. Materials and methods: A total of 340 patients under 18 years of age who received restorative-surgical dental treatment between 2011 and 2022 were anonymously enrolled. Demographic and other patient-specific data, general medical health, oral health, and treatment related data were recorded. In addition to descriptive analysis, Spearman-Rho-test, Mann-Whitney-U-test, Kruskall-Wallis-test and Chi-square-test were used. Results: More than half of the patients (52,6%) were in general health, but non-cooperative. The majority of the patients (66.8%) was between 1 and 5 years of age (p < 0,001). Mean dmft was 10.95 ± 4.118, mean DMFT was 10.09 ± 7.885, and mean dt/DT was 10.79 ± 4.273. Analysis showed that communication difficulties significantly influenced dmft (p = 0.004), DMFT (p = 0.019), and dt/DT (p < 0.001). Type of insurance significantly affected dmft (p = 0.004) and dt/DT (p = 0.001). There was no significant effect of ASA on caries experience, however on prevalence of severe gingivitis (p < 0.001), number of extractions (p = 0.002), and need for repeated treatment (p < 0.001). Conclusions: Need for dental treatment in the present collective was high, independent of the considered variables. Non-Cooperativeness along with ECC was the main indication for dental general anesthesia. The mixed dt/DT was the most precise survey to evaluate clinical treatment needs. Clinical relevance: Given the enormous demand for these rehabilitations with strict selection, it is imperative to create more treatment capacities for patients mandatorily requiring general anesthesia by avoiding it in healthy patients.
MeSH term(s)	Humans ; Child ; Adolescent ; Dental Caries/therapy ; Dental Caries/epidemiology ; Retrospective Studies ; Dental Care ; Health Status ; Anesthesia, General ; Prevalence ; DMF Index
Language	English
Publishing date	2023-05-23
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1364490-7
ISSN	1436-3771 ; 1432-6981
ISSN (online)	1436-3771
ISSN	1432-6981
DOI	10.1007/s00784-023-05041-y
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Zs.A 4788: Show issues

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Article ; Online: Bacterial contamination potential of personal protective equipment itself in dental aerosol-producing treatments.

Gund, Madline Priska / Naim, Jusef / Rupf, Stefan / Gärtner, Barbara / Hannig, Matthias

Odontology

2023 Volume 112, Issue 2, Page(s) 309–316

Abstract: Personal protective equipment (PPE) has long been a high priority in dental aerosol-producing treatments. Since COVID-19 pandemic, its importance has increased yet again. While importance of PPE in preventing transmission and thus possible infection of ... ...

Abstract	Personal protective equipment (PPE) has long been a high priority in dental aerosol-producing treatments. Since COVID-19 pandemic, its importance has increased yet again. While importance of PPE in preventing transmission and thus possible infection of pathogens is well known, contamination potential of PPE after treatment itself is less investigated. This review aims to give an overview of the current literature and contamination potential (viral, blood, bacterial) of components of protective equipment itself. The literature search was performed using the Medline database; furthermore, a hand search was conducted. Last search took place on 23 November 2022. Two categories of hygiene-related keywords were formed (category A: mask, face shield, goggles, eyewear, personal protective equipment; category B: contamination, aerosol). Each keyword from one category was combined with all keywords from the other one. In addition, the keyword "dental" was always added. First, a title and abstract screening was performed. Afterward, a full-text analysis was followed for the included studies. A total of 648 search hits were found in the Medline database. 47 were included after title and abstract screening. 22 studies were excluded after full-text analysis, 25 studies were included. The hand search resulted in 4 studies that were included. Bacterial contamination of PPE after treatment has been adequately studied, contamination with blood less. Microorganisms mainly originate from the oral and cutaneous flora; however, a transmission of potential pathogens like Staphylococcus aureus or Escherichia coli was also described. Studies showing transmission pathways starting from PPE and its various components are lacking. No measures have yet been described that fully protect the protective equipment from contamination. There is growing awareness that PPE itself can be a source of pathogen transmission, and thus possible infection. Therefore, not only wearing of protective clothing, but also conscious handling of it is crucial for transmission and possible infection prevention. However, studies showing transmission pathways starting from PPE and its various components are lacking. Several studies have investigated what measures can be taken to protect the protective equipment itself. So far, none of the methods evaluated can prevent contamination of PPE.
MeSH term(s)	Humans ; Pandemics/prevention & control ; Infectious Disease Transmission, Patient-to-Professional/prevention & control ; Respiratory Aerosols and Droplets ; Personal Protective Equipment ; COVID-19/prevention & control
Language	English
Publishing date	2023-09-13
Publishing country	Japan
Document type	Journal Article ; Review
ZDB-ID	2092085-4
ISSN	1618-1255 ; 1618-1247
ISSN (online)	1618-1255
ISSN	1618-1247
DOI	10.1007/s10266-023-00848-3
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Article ; Online: Nutritional and Oral Hygiene Knowledge versus Reported Behavior of Children and Adolescents-A Cross-Sectional Interview-Based Study.

Gund, Madline P / Unshelm, Carola / Hannig, Matthias / Rupf, Stefan

International journal of environmental research and public health

2022 Volume 19, Issue 16

Abstract: Despite the fact that healthy, sugar-reduced nutrition has been propagated by the media and in schools for years, dental caries in children remains a major health problem worldwide, caused primarily by an unhealthy diet. The objective of this study is to ...

Abstract	Despite the fact that healthy, sugar-reduced nutrition has been propagated by the media and in schools for years, dental caries in children remains a major health problem worldwide, caused primarily by an unhealthy diet. The objective of this study is to compare statements on nutrition and hygienic knowledge with those on children's actual dietary and hygienic behavior. A random sample of 554 children and adolescents aged 3-19 years was enrolled. Designed as a cross-sectional interview-based community survey, this study was conducted consecutively during three one-day public science-promoting events at the Saarland University's Medical Faculty. Participants' oral hygiene and nutritional knowledge was profound; however, the reported translation into practice showed deficiencies. Boys and younger children (3-10 years) often showed better oral hygiene knowledge than girls and older children (over 11 years) but had problems implementing it into their daily life practice. In contrast, girls and older children often showed less oral hygiene knowledge but reported more favorable behavior. Finally, children up to the mixed dentition phase preferred drinking sweets more often than older children, posing a risk to the developing permanent dentition. Intensifying well-known controlled motivation training approaches to encourage children and adolescents is recommended to put their knowledge into practice.
MeSH term(s)	Adolescent ; Child ; Cross-Sectional Studies ; Dental Caries ; Diet ; Feeding Behavior ; Female ; Humans ; Male ; Oral Health ; Oral Hygiene
Language	English
Publishing date	2022-08-15
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph191610055
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