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Article ; Online: Rapid Transcoronary Pacing to Facilitate Ostial Stent Placement.

Mallek, Khaled / Dalton, Richard T / Pareek, Nilesh / Dworakowski, Rafal

2021 Volume 14, Issue 10, Page(s) e111–e112

MeSH term(s)	Angioplasty, Balloon, Coronary ; Coronary Angiography ; Humans ; Percutaneous Coronary Intervention/adverse effects ; Stents ; Treatment Outcome
Language	English
Publishing date	2021-04-28
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2452157-7
ISSN	1876-7605 ; 1936-8798
ISSN (online)	1876-7605
ISSN	1936-8798
DOI	10.1016/j.jcin.2021.02.010
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Zs.A 6669: Show issues

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Article ; Online: Adjunctive Rotational Atherectomy and Intravascular Lithotripsy for Heavily Calcified Left Main Disease Via Radial Access.

Macaya, Fernando / Yeoh, Julian / Hill, Jonathan / Dworakowski, Rafal

The Journal of invasive cardiology

2020 Volume 32, Issue 4, Page(s) E99

Abstract: Coronary angiography demonstrated severe distal left main disease in a patient with heavy concentric calcification extending into the left anterior descending and left circumflex arteries. Rotational atherectomy and lithotripsy were used to debulk plaque ...

Abstract	Coronary angiography demonstrated severe distal left main disease in a patient with heavy concentric calcification extending into the left anterior descending and left circumflex arteries. Rotational atherectomy and lithotripsy were used to debulk plaque so that stenting could be performed.
MeSH term(s)	Atherectomy, Coronary/adverse effects ; Coronary Angiography ; Coronary Artery Disease/diagnosis ; Coronary Artery Disease/surgery ; Humans ; Lithotripsy ; Treatment Outcome ; Vascular Calcification/diagnostic imaging ; Vascular Calcification/surgery
Language	English
Publishing date	2020-03-06
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	1154372-3
ISSN	1557-2501 ; 1042-3931
ISSN (online)	1557-2501
ISSN	1042-3931
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Zs.A 3701: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Insights into microorganisms, associated factors, and the oral microbiome in infective endocarditis patients.

Ismail, Ayden / Yogarajah, Amieth / Falconer, Joseph Luke / Dworakowski, Rafal / Watson, Samuel / Breeze, Jonathan / Gunning, Margaret / Khan, Habib / Hussain, Azhar / Howard, James P / Cheong, Phoebe / Shah, Mira / Nibali, Luigi / Sousa, Vanessa

Frontiers in oral health

2024 Volume 5, Page(s) 1270492

Abstract: Introduction: Infective Endocarditis (IE) is a rare, life-threatening infection of the endocardium with multisystem effects. Culprit microorganisms derived from different niches circulate through the bloodstream and attach to the endocardium, ... ...

Abstract	Introduction: Infective Endocarditis (IE) is a rare, life-threatening infection of the endocardium with multisystem effects. Culprit microorganisms derived from different niches circulate through the bloodstream and attach to the endocardium, particularly the heart valves. This study aimed to investigate culprit microorganisms among a cross-sectional cohort of IE patients, their associated factors, and to explore the potential relationship to the oral microbiome. Methods: In this observational study, we undertook a cross-sectional analysis of 392 medical records from patients diagnosed with IE. The primary outcome of this study was to analyse the association between the IE culprit microorganisms and the underlying anatomical types of IE (native valve (NVE), prosthetic valve (PVE), or cardiac device-related (CDE)). Secondary outcomes encompassed a comparative analysis of additional factors, including: the treatment approaches for IE, and the categorisation of blood cultures, extending to both genus and species levels. Additionally, we cross-referenced and compared the species-level identification of IE bacteraemia outcome measures with data from the expanded Human Oral Microbiome Database (eHOMD). Results: A culprit microorganism was identified in 299 (76.28%) case participants. Staphylococcal infections were the most common ( Conclusions: This study demonstrated that IE patients with a history of stroke, smoking, intravenous drug use, or dialysis were more likely to be infected with
Language	English
Publishing date	2024-04-11
Publishing country	Switzerland
Document type	Journal Article
ISSN	2673-4842
ISSN (online)	2673-4842
DOI	10.3389/froh.2024.1270492
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Article ; Online: TRANSCATHETER AORTIC VALVE REPLACEMENT WITH THE NAVITOR SYSTEM: REAL-WORLD UNITED KINGDOM EXPERIENCE.

Bharucha, Apurva H / Kanyal, Ritesh / Mullen, Michael / Patel, Kush / Smith, David / Shome, Joy / Blackman, Daniel J / Aktaa, Suleman / Williams, Paul D / Khogali, Saib / Dworakowski, Rafal / Eskandari, Mehdi / Byrne, Jonathan / MacCarthy, Philip

The American journal of cardiology

2024

Abstract: Background: The Navitor (THV) is the latest iteration of the Portico self-expanding valve system. Early prospective studies have shown promising outcomes, however there is a lack of complementary 'real-world' data.: Aims: To assess early safety and ... ...

Abstract	Background: The Navitor (THV) is the latest iteration of the Portico self-expanding valve system. Early prospective studies have shown promising outcomes, however there is a lack of complementary 'real-world' data. Aims: To assess early safety and efficacy outcomes of the Navitor Transcatheter Heart Valve (THV) using registry data from six high-volume UK TAVR centers. Methods: Demographic, procedural and in-hospital outcome data were retrieved from six UK centers. The primary safety end-point was 30-day mortality. Primary efficacy end-points were procedural success, mean aortic gradient, and ≥moderate paravalvular leak (PVL). Secondary endpoints included rates of new pacemaker implantation (PPM), stroke and vascular injury. Results: 574 patients (Mean age 83.4 years; 54.5% female) underwent Navitor TAVR between January 2020 and May 2023. The 30-day mortality in this patient cohort was 1.6%. Procedural success was 98.1%, mean echo-derived gradient post-TAVR was 7.7±4.8mmHg (95% CI [7.2, 8.3], p<0.001) and 5.1% of patients had ≥moderate PVL (p̂=0.051, 95% CI [0.035, 0.073, p<0.001). New PPM to discharge was required in 11% (p̂ =0.119, 95% CI [0.088, 0.158], p<0.001), stroke occurred in 1.2% of patients (p̂= 0.017, 95% CI [0.006, 0.036], p<0.001) and significant vascular injury in 1.6% (p̂= 0.014, 95% CI [0.005, 0.032], p<0.001). Conclusion: Early procedural outcomes with Navitor TAVR compare favorably to new generation THVs. Procedural success was high with a low incidence of complications.
Language	English
Publishing date	2024-04-29
Publishing country	United States
Document type	Journal Article
ZDB-ID	80014-4
ISSN	1879-1913 ; 0002-9149
ISSN (online)	1879-1913
ISSN	0002-9149
DOI	10.1016/j.amjcard.2024.04.036
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Article ; Online: Infective endocarditis - Cinderella in cardiology.

Kaura, Amit / Dworakowska, Dorota / Dworakowski, Rafal

Kardiologia polska

2017 Volume 75, Issue 10, Page(s) 965–974

Language	English
Publishing date	2017
Publishing country	Poland
Document type	Journal Article
ZDB-ID	411492-9
ISSN	1897-4279 ; 0022-9032
ISSN (online)	1897-4279
ISSN	0022-9032
DOI	10.5603/KP.a2017.0099
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Zs.B 598: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MO 474: Show issues

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Article ; Online: Spontaneous coronary artery dissection after COVID-19 infection presenting with ST segment elevation.

Cannata, Stefano / Birkinshaw, Alexander / Sado, Daniel / Dworakowski, Rafal / Pareek, Nilesh

European heart journal

2020 Volume 41, Issue 48, Page(s) 4602

MeSH term(s)	Antibodies, Viral/blood ; COVID-19/complications ; Coronary Angiography ; Coronary Vessel Anomalies/diagnostic imaging ; Coronary Vessel Anomalies/drug therapy ; Coronary Vessel Anomalies/virology ; Electrocardiography ; Female ; Humans ; Middle Aged ; SARS-CoV-2/immunology ; Troponin T/blood ; Vascular Diseases/congenital ; Vascular Diseases/diagnostic imaging ; Vascular Diseases/drug therapy ; Vascular Diseases/virology ; Ventricular Dysfunction, Left/diagnostic imaging ; Ventricular Dysfunction, Left/drug therapy
Chemical Substances	Antibodies, Viral ; Troponin T
Language	English
Publishing date	2020-12-18
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	603098-1
ISSN	1522-9645 ; 0195-668X
ISSN (online)	1522-9645
ISSN	0195-668X
DOI	10.1093/eurheartj/ehaa813
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Zs.A 1563: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 640: Show issues

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Article ; Online: A contemporary and complete treatment solution for a high-risk patient with critical aortic stenosis, left ventricular thrombus, severe left ventricular dysfunction, and calcified left main stem disease.

Yeoh, Julian / Dworakowski, Rafal / Hill, Jonathan / Byrne, Jonathan

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

2019 Volume 95, Issue 4, Page(s) 851–854

Abstract: The combination of severe coronary disease, significant valvular dysfunction and impaired ventricular function pose patients at a very high procedural risk. In addition, the presence of left ventricular thrombus can complicate ventricular instrumentation ...

Abstract	The combination of severe coronary disease, significant valvular dysfunction and impaired ventricular function pose patients at a very high procedural risk. In addition, the presence of left ventricular thrombus can complicate ventricular instrumentation increasing embolic risk. Contemporary techniques and devices have now become available to overcome these challenges to reduce risk and allow safer, more efficient procedures. We describe the feasibility of using Impella CP™ with cerebral protection to facilitate complete revascularisation and percutaneous valve replacement in a patient with critical aortic stenosis, severe left ventricular (LV) impairment, LV thrombus and a calcified left main stem disease.
MeSH term(s)	Aged ; Angioplasty, Balloon, Coronary/instrumentation ; Aortic Valve Stenosis/diagnostic imaging ; Aortic Valve Stenosis/physiopathology ; Aortic Valve Stenosis/therapy ; Balloon Valvuloplasty ; Coronary Artery Disease/diagnostic imaging ; Coronary Artery Disease/physiopathology ; Coronary Artery Disease/therapy ; Drug-Eluting Stents ; Embolic Protection Devices ; Female ; Heart Valve Prosthesis ; Heart-Assist Devices ; Humans ; Recovery of Function ; Severity of Illness Index ; Thrombosis/diagnostic imaging ; Thrombosis/physiopathology ; Thrombosis/therapy ; Transcatheter Aortic Valve Replacement/instrumentation ; Treatment Outcome ; Vascular Calcification/diagnostic imaging ; Vascular Calcification/physiopathology ; Vascular Calcification/therapy ; Ventricular Dysfunction, Left/diagnostic imaging ; Ventricular Dysfunction, Left/physiopathology ; Ventricular Dysfunction, Left/therapy ; Ventricular Function, Left
Language	English
Publishing date	2019-10-15
Publishing country	United States
Document type	Case Reports ; Video-Audio Media
ZDB-ID	1459995-8
ISSN	1522-726X ; 1522-1946
ISSN (online)	1522-726X
ISSN	1522-1946
DOI	10.1002/ccd.28521
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Zs.A 1226: Show issues

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Article ; Online: Zaburzenia przewodzenia a TAVI.

Dworakowski, Rafał

Kardiologia polska

2012 Volume 70, Issue 2, Page(s) 129–130

Title translation	Conduction disturbances and TAVI.
MeSH term(s)	Aortic Valve Stenosis/therapy ; Arrhythmias, Cardiac/etiology ; Bioprosthesis/adverse effects ; Cardiac Pacing, Artificial/methods ; Female ; Heart Valve Prosthesis/adverse effects ; Heart Valve Prosthesis Implantation/adverse effects ; Humans ; Male
Language	Polish
Publishing date	2012
Publishing country	Poland
Document type	Comment ; Editorial
ZDB-ID	411492-9
ISSN	1897-4279 ; 0022-9032
ISSN (online)	1897-4279
ISSN	0022-9032
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Zs.B 598: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
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Article: Three-dimensional printing in modelling mitral valve interventions.

Bharucha, Apurva H / Moore, John / Carnahan, Patrick / MacCarthy, Philip / Monaghan, Mark J / Baghai, Max / Deshpande, Ranjit / Byrne, Jonathan / Dworakowski, Rafal / Eskandari, Mehdi

Echo research and practice

2023 Volume 10, Issue 1, Page(s) 12

Abstract: Mitral interventions remain technically challenging owing to the anatomical complexity and heterogeneity of mitral pathologies. As such, multi-disciplinary pre-procedural planning assisted by advanced cardiac imaging is pivotal to successful outcomes. ... ...

Abstract	Mitral interventions remain technically challenging owing to the anatomical complexity and heterogeneity of mitral pathologies. As such, multi-disciplinary pre-procedural planning assisted by advanced cardiac imaging is pivotal to successful outcomes. Modern imaging techniques offer accurate 3D renderings of cardiac anatomy; however, users are required to derive a spatial understanding of complex mitral pathologies from a 2D projection thus generating an 'imaging gap' which limits procedural planning. Physical mitral modelling using 3D printing has the potential to bridge this gap and is increasingly being employed in conjunction with other transformative technologies to assess feasibility of intervention, direct prosthesis choice and avoid complications. Such platforms have also shown value in training and patient education. Despite important limitations, the pace of innovation and synergistic integration with other technologies is likely to ensure that 3D printing assumes a central role in the journey towards delivering personalised care for patients undergoing mitral valve interventions.
Language	English
Publishing date	2023-08-02
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2777997-X
ISSN	2055-0464
ISSN	2055-0464
DOI	10.1186/s44156-023-00024-x
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Article ; Online: Single arterial access closure of post-infarction ventricular septal defect: A case series.

Doost, Ata / Chilmeran, Ahmed / Gomes, Arionilson / Dworakowski, Rafal / Eskandari, Mehdi / MacCarthy, Philip / Cockburn, James / Byrne, Jonathan / Hildick-Smith, David

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

2022 Volume 101, Issue 1, Page(s) 209–216

Abstract: Background: Post-infarction ventricular septal defect (PIVSD) carries a very poor prognosis. Surgical repair offers reasonable outcomes in patients who survive the initial healing period. Percutaneous device implantation remains a potentially effective ... ...

Abstract	Background: Post-infarction ventricular septal defect (PIVSD) carries a very poor prognosis. Surgical repair offers reasonable outcomes in patients who survive the initial healing period. Percutaneous device implantation remains a potentially effective earlier alternative. Methods and results: From March 2018 to May 2022, 11 trans-arterial PIVSD closures were attempted in 9 patients from two centers (aged 67.2 ± 11.1 years; 77.8% male). Two patients had a second procedure. Myocardial infarction was anterior in four patients (44.5%) and inferior in five cases (55.5%). Devices were successfully implanted in all patients. There were no major immediate procedural complications. Immediate shunt grade postprocedure was significant (11.1%), minimal (77.8%), or none (11.1%). Median length of stay after the procedure was 14.8 days. Five patients (55%) survived to discharge and were followed up for a median of 605 days, during which time no additional patients died. Conclusion: Single arterial access for percutaneous closure of PIVSD is a good option for these extremely high-risk patients, in the era of effective large-bore arterial access closure. Mortality remains high, but patients who survive to discharge do well in the longer term.
MeSH term(s)	Humans ; Male ; Female ; Cardiac Surgical Procedures/adverse effects ; Treatment Outcome ; Cardiac Catheterization/adverse effects ; Cardiac Catheterization/methods ; Heart Septal Defects, Ventricular/surgery ; Myocardial Infarction/complications ; Myocardial Infarction/diagnostic imaging ; Myocardial Infarction/therapy ; Anterior Wall Myocardial Infarction/complications ; Septal Occluder Device/adverse effects
Language	English
Publishing date	2022-12-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	1459995-8
ISSN	1522-726X ; 1522-1946
ISSN (online)	1522-726X
ISSN	1522-1946
DOI	10.1002/ccd.30510
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