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  1. Article: Red blood cell distribution width and renal cell carcinoma: A comparative analysis of peer-reviewed studies.

    Frater, John L / Hurley, M Yadira

    Translational oncology

    2022  Volume 26, Page(s) 101558

    Language English
    Publishing date 2022-10-10
    Publishing country United States
    Document type Letter
    ZDB-ID 2443840-6
    ISSN 1936-5233
    ISSN 1936-5233
    DOI 10.1016/j.tranon.2022.101558
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Red blood cell distribution width in elderly populations and its implications for clinical studies.

    Frater, John L / Hurley, M Yadira

    Archives of gerontology and geriatrics

    2022  Volume 101, Page(s) 104675

    MeSH term(s) Aged ; Erythrocyte Indices ; Erythrocytes ; Humans ; Retrospective Studies
    Language English
    Publishing date 2022-03-08
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 603162-6
    ISSN 1872-6976 ; 0167-4943
    ISSN (online) 1872-6976
    ISSN 0167-4943
    DOI 10.1016/j.archger.2022.104675
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    In stock of ZB MED Cologne/Königswinter

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  3. Article ; Online: Red blood cell distribution width as a biomarker: the importance of age-dependent changes and other variables.

    Frater, John L / Hurley, M Yadira

    Aging clinical and experimental research

    2022  Volume 35, Issue 4, Page(s) 897

    MeSH term(s) Humans ; Erythrocyte Indices ; Biomarkers ; Erythrocytes
    Chemical Substances Biomarkers
    Language English
    Publishing date 2022-12-06
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 2104785-6
    ISSN 1720-8319 ; 1594-0667
    ISSN (online) 1720-8319
    ISSN 1594-0667
    DOI 10.1007/s40520-022-02315-5
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  4. Article: Complete Blood Cell Count-Derived Biomarkers and Clinical Studies: Is It Time for New Reporting Criteria? Comment on Anand et al. Utility of Red Cell Distribution Width (RDW) as a Noninvasive Biomarker for the Diagnosis of Acute Appendicitis: A Systematic Review and Meta-Analysis of 5222 Cases.

    Frater, John L / Hurley, M Yadira

    Diagnostics (Basel, Switzerland)

    2022  Volume 12, Issue 10

    Abstract: We read with great interest the article entitled "Utility of Red Cell Distribution Width (RDW) as a Noninvasive Biomarker for the Diagnosis of Acute Appendicitis: A Systematic Review and Meta-Analysis of 5222 Cases" by S. Anand et al. which has been ... ...

    Abstract We read with great interest the article entitled "Utility of Red Cell Distribution Width (RDW) as a Noninvasive Biomarker for the Diagnosis of Acute Appendicitis: A Systematic Review and Meta-Analysis of 5222 Cases" by S. Anand et al. which has been recently published in
    Language English
    Publishing date 2022-09-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics12102329
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  5. Article ; Online: Excitation Energy-Dependent, Excited-State Intramolecular Proton Transfer-Based Dual Emission in Poor Hydrogen-Bonding Solvents.

    Hurley, Joseph J M / Zhu, Lei

    The journal of physical chemistry. A

    2022  Volume 126, Issue 34, Page(s) 5711–5720

    Abstract: 2-(2'-Hydroxyphenyl)benzoxazole (HBO) substituted at the 5'-position with bipyridylvinylene phenylenevinylene ( ... ...

    Abstract 2-(2'-Hydroxyphenyl)benzoxazole (HBO) substituted at the 5'-position with bipyridylvinylene phenylenevinylene (compound
    Language English
    Publishing date 2022-08-18
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5215
    ISSN (online) 1520-5215
    DOI 10.1021/acs.jpca.2c03668
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  6. Article: Dupilumab-induced pityriasis rosea in a 28-year-old male with atopic dermatitis.

    Yousefian, Faraz / Hurley, Margaret / Ali, Liaqat / Goodman, Marcus / Rupley, Katherine

    JAAD case reports

    2024  Volume 45, Page(s) 77–78

    Language English
    Publishing date 2024-01-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2834220-3
    ISSN 2352-5126
    ISSN 2352-5126
    DOI 10.1016/j.jdcr.2023.12.019
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  7. Article: Presentation and Management of a Traumatic Right Sided Diaphragmatic Hernia: A Case Report.

    Benson, Austin / Hurley, Luke / Bauer, Michael

    South Dakota medicine : the journal of the South Dakota State Medical Association

    2023  Volume 75, Issue 12, Page(s) 546–548

    Abstract: Traumatic diaphragmatic injury (TDI) is a rare and dangerous sequela of trauma. Right sided TDI is even more uncommon due to the usual protection of the diaphragm by the liver. TDI can present in a delayed fashion, making diagnosis difficult to obtain. ... ...

    Abstract Traumatic diaphragmatic injury (TDI) is a rare and dangerous sequela of trauma. Right sided TDI is even more uncommon due to the usual protection of the diaphragm by the liver. TDI can present in a delayed fashion, making diagnosis difficult to obtain. In any case TDI needs to be taken very seriously as it can lead to bowel strangulation and require emergency surgery. Multiple approaches have been described in order to definitively repair diaphragmatic defects. This report describes a patient who developed a delayed onset right sided diaphragmatic hernia after experiencing blunt trauma.
    MeSH term(s) Humans ; Diaphragm/injuries ; Abdominal Injuries ; Liver ; Thoracic Injuries/diagnosis ; Hernia, Diaphragmatic
    Language English
    Publishing date 2023-03-09
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2278073-7
    ISSN 0038-3317
    ISSN 0038-3317
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 205: Show issues Location:
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  8. Article ; Online: Fibroblast Growth Factor 23 Neutralizing Antibody Ameliorates Abnormal Renal Phosphate Handling in Sickle Cell Disease Mice.

    Xiao, Liping / Clarke, Kai / Hurley, Marja M

    Endocrinology

    2023  Volume 164, Issue 12

    Abstract: We assessed the involvement of fibroblast growth factor 23 (FGF23) in phosphaturia in sickle cell disease (SCD) mice. Control and SCD mice were treated with FGF23 neutralizing antibody (FGF23Ab) for 24 hours. Serum ferritin was significantly increased in ...

    Abstract We assessed the involvement of fibroblast growth factor 23 (FGF23) in phosphaturia in sickle cell disease (SCD) mice. Control and SCD mice were treated with FGF23 neutralizing antibody (FGF23Ab) for 24 hours. Serum ferritin was significantly increased in SCD mice and was significantly reduced in female but not male SCD mice by FGF23Ab. FGF23Ab significantly reduced increased erythropoietin in SCD kidneys. Serum intact FGF23 was significantly increased in SCD female mice and was markedly increased in SCD male mice; however, FGF23Ab significantly reduced serum intact FGF23 in both genotypes and sexes. Serum carboxy-terminal-fragment FGF23 (cFGF23) was significantly reduced in SCD IgG male mice and was markedly but not significantly reduced in SCD IgG female mice. FGF23Ab significantly increased cFGF23 in both sexes and genotypes. Serum 1,25-dihydroxyvitamin D3 was significantly increased in SCD IgG and was further significantly increased by FGF23Ab in both sexes and genotypes. Significantly increased blood urea nitrogen in SCD was not reduced by FGF23Ab. The urine phosphate (Pi)/creatinine ratio was significantly increased in SCD in both sexes and was significantly reduced by FGF23Ab. Increased SCD kidney damage marker kidney injury molecule 1 was rescued, but sclerotic glomeruli, increased macrophages, and lymphocytes were not rescued by short-term FGF23Ab. FGF23Ab significantly reduced increased phospho-fibroblast growth factor receptor 1, αKlotho, phosphorylated extracellular signal-regulated kinase, phosphorylated serum/glucocorticoid-regulated kinase 1, phosphorylated sodium-hydrogen exchanger regulatory factor-1, phosphorylated janus kinase 3, and phosphorylated transducer and activator of transcription-3 in SCD kidneys. The type II sodium Pi cotransporter (NPT2a) and sodium-dependent Pi transporter PiT-2 proteins were significantly reduced in SCD kidneys and were increased by FGF23Ab. We conclude that increased FGF23/FGF receptor 1/αKlotho signaling promotes Pi wasting in SCD by downregulating NPT2a and PIT2 via modulation of multiple signaling pathways that could be rescued by FGF23Ab.
    MeSH term(s) Female ; Male ; Animals ; Mice ; Phosphates ; Fibroblast Growth Factor-23 ; Kidney ; Anemia, Sickle Cell/drug therapy ; Antibodies, Neutralizing ; Sodium ; Immunoglobulin G
    Chemical Substances Phosphates ; Fibroblast Growth Factor-23 (7Q7P4S7RRE) ; Antibodies, Neutralizing ; Sodium (9NEZ333N27) ; Immunoglobulin G
    Language English
    Publishing date 2023-11-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 427856-2
    ISSN 1945-7170 ; 0013-7227
    ISSN (online) 1945-7170
    ISSN 0013-7227
    DOI 10.1210/endocr/bqad173
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  9. Article ; Online: Effect of Patient Characteristics on the Minimal Clinically Important Difference and Patient Acceptable Symptom State Thresholds After Arthroscopic Bankart Repair.

    Pasqualini, Ignacio / Tanoira, Ignacio / Hurley, Eoghan T / Ranalletta, Maximiliano / Andrés Rossi, Luciano

    The American journal of sports medicine

    2024  Volume 52, Issue 1, Page(s) 174–180

    Abstract: Background: There is scarce literature on clinically significant values after arthroscopic Bankart repair (ABR).: Purpose: To determine the minimal clinically important difference (MCID) and the patient acceptable symptom state (PASS) thresholds at 1 ...

    Abstract Background: There is scarce literature on clinically significant values after arthroscopic Bankart repair (ABR).
    Purpose: To determine the minimal clinically important difference (MCID) and the patient acceptable symptom state (PASS) thresholds at 1 year for the Rowe and Athletic Shoulder Outcome Scoring System (ASOSS) scores after ABR and to determine the effect of patient characteristics on these metrics after ABR.
    Study design: Case series; Level of evidence, 4.
    Methods: A retrospective review of patients undergoing ABR from a single institution between January 2017 and January 2020 was performed. Patients with at least 1 episode of instability and a minimum follow-up of 12 months were included. The exclusion criteria were as follows: bony defects of >20% on the anteroinferior portion of the glenoid based on a preoperative computed tomography scan; engaging Hill-Sachs lesions at 90° of abduction and 90° of external rotation based on an arthroscopic examination; previous surgery on the same shoulder; multidirectional instability or concomitant repair of full-thickness rotator cuff tears; superior labral anterior to posterior lesions; posterior labral tears; or humeral avulsion of the glenohumeral ligament lesions. Patient-reported outcome measures were collected both preoperatively and 1-year postoperatively. Delta was defined as the change between preoperative and 1-year postoperative scores. Distribution-based (one-half the standard deviation of the difference between pre- and postoperative outcome scores) and anchored-based approaches (response to a satisfaction question at 1 year) were used to estimate the MCID and the PASS, respectively. The optimal cutoff point, where sensitivity and specificity were maximized, and the percentage of patients achieving those thresholds were also calculated.
    Results: Overall, 190 patients were included. The distribution-based MCID for the Rowe and ASOSS scores were calculated to be 8.2 and 8.7, respectively. The rate of patients who achieved MCID thresholds was 96% for the Rowe and 96% for ASOSS scores. The PASS threshold for the Rowe and ASOSS scores were ≥80 and ≥90, respectively. The rate of patients who achieved PASS scores after ABR were 86% and 83%, respectively. The MCID and PASS values showed great variability based on sex (men: 8.5 and ≥85 for Rowe / 8.9 and ≥90 for ASOSS, respectively, vs women: 6.7 and ≥73 for Rowe / 8.1 and ≥75 for ASOSS), age (≥21: 8.4 and ≥80 / 9.2 and ≥90 vs <21: 7.8 and ≥75 / 7.7 and ≥85), sports participation (sports: 8.8 and ≥85 / 9.5 and ≥90 vs no sports: 8.1 and ≥75 / 8.6 and ≥80), and type of athlete (competitive: 8.4 and ≥85 / 8.9 and ≥87 vs recreational: 7.5 and ≥73 / 8.1 and ≥68).
    Conclusion: This study identified the MCID and PASS thresholds for the Rowe and ASOSS scores at 1 year after ABR. However, these values showed great variability when accounting for different patient characteristics such as sex, age, sports participation, and type of athlete, highlighting the importance of considering individual patient-specific characteristics for optimal treatment decision-making and ensuring treatment success tailored to each patient's unique needs and expectations.
    MeSH term(s) Male ; Humans ; Female ; Minimal Clinically Important Difference ; Arthroscopy/methods ; Shoulder Joint/diagnostic imaging ; Shoulder Joint/surgery ; Arthroplasty ; Retrospective Studies ; Treatment Outcome ; Joint Instability/diagnostic imaging ; Joint Instability/surgery ; Joint Instability/complications ; Shoulder Dislocation/surgery
    Language English
    Publishing date 2024-02-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 197482-8
    ISSN 1552-3365 ; 0363-5465
    ISSN (online) 1552-3365
    ISSN 0363-5465
    DOI 10.1177/03635465231212652
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  10. Article ; Online: Gait disturbances and muscle dysfunction in fibroblast growth factor 2 knockout mice.

    Homer-Bouthiette, C / Xiao, L / Hurley, Marja M

    Scientific reports

    2021  Volume 11, Issue 1, Page(s) 11005

    Abstract: Fibroblast growth factor 2 (FGF2) is important in musculoskeletal homeostasis, therefore the impact of reduction or Fgf2 knockout on skeletal muscle function and phenotype was determined. Gait analysis as well as muscle strength testing in young and old ... ...

    Abstract Fibroblast growth factor 2 (FGF2) is important in musculoskeletal homeostasis, therefore the impact of reduction or Fgf2 knockout on skeletal muscle function and phenotype was determined. Gait analysis as well as muscle strength testing in young and old WT and Fgf2KO demonstrated age-related gait disturbances and reduction in muscle strength that were exacerbated in the KO condition. Fgf2 mRNA and protein were significantly decreased in skeletal muscle of old WT compared with young WT. Muscle fiber cross-sectional area was significantly reduced with increased fibrosis and inflammatory infiltrates in old WT and Fgf2KO vs. young WT. Inflammatory cells were further significantly increased in old Fgf2KO compared with old WT. Lipid-related genes and intramuscular fat was increased in old WT and old Fgf2KO with a further increase in fibro-adipocytes in old Fgf2KO compared with old WT. Impaired FGF signaling including Increased β-Klotho, Fgf21 mRNA, FGF21 protein, phosphorylated FGF receptors 1 and 3, was observed in old WT and old Fgf2KO. MAPK/ ERK1/2 was significantly increased in young and old Fgf2KO. We conclude that Fgf2KO, age-related decreased FGF2 in WT mice, and increased FGF21 in the setting of impaired Fgf2 expression likely contribute to impaired skeletal muscle function and sarcopenia in mice.
    MeSH term(s) Adipocytes/metabolism ; Animals ; Fibroblast Growth Factor 2 ; Gait ; Male ; Mice ; Muscle Fibers, Skeletal/metabolism ; Muscle, Skeletal ; Sarcopenia ; Signal Transduction
    Chemical Substances Fibroblast Growth Factor 2 (103107-01-3)
    Language English
    Publishing date 2021-05-26
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-021-90565-0
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