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  1. Article ; Online: Switchable divergent synthesis of chiral indole derivatives

    Liu, Tingting / Wang, Jianbin / Xiao, Rou / Zhao, Junling

    RSC advances

    2024  Volume 14, Issue 22, Page(s) 15591–15596

    Abstract: A strategy allowing the switchable divergent synthesis of chiral indole derivatives was ... ...

    Abstract A strategy allowing the switchable divergent synthesis of chiral indole derivatives was established
    Language English
    Publishing date 2024-05-14
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d4ra03231d
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Genomics of the Parasitic Nematode

    Wang, Jianbin

    Genes

    2021  Volume 12, Issue 4

    Abstract: Nematodes of the ... ...

    Abstract Nematodes of the genus
    MeSH term(s) Animals ; Ascariasis/parasitology ; Ascariasis/veterinary ; Ascaris/classification ; Ascaris/genetics ; Ascaris/physiology ; Databases, Genetic ; Gene Expression Regulation, Developmental ; Genome, Protozoan ; Humans ; Swine ; Transcriptome
    Language English
    Publishing date 2021-03-28
    Publishing country Switzerland
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2527218-4
    ISSN 2073-4425 ; 2073-4425
    ISSN (online) 2073-4425
    ISSN 2073-4425
    DOI 10.3390/genes12040493
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Intelligent

    Wang, Qi / Li, Yutao / Xiao, Jianbin / Xia, Lin

    Polymers

    2023  Volume 15, Issue 5

    Abstract: ... ...

    Abstract Intelligent
    Language English
    Publishing date 2023-02-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym15051182
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Genome Analysis of Programmed DNA Elimination in Parasitic Nematodes.

    Wang, Jianbin

    Methods in molecular biology (Clifton, N.J.)

    2021  Volume 2369, Page(s) 251–261

    Abstract: Two distinct groups of parasitic nematodes use programmed DNA elimination to silence germline-expressed genes in the somatic cells (ascarids) or for sex determination (Strongyloides spp.). In the ascarids, DNA is lost only in pre-somatic cells during ... ...

    Abstract Two distinct groups of parasitic nematodes use programmed DNA elimination to silence germline-expressed genes in the somatic cells (ascarids) or for sex determination (Strongyloides spp.). In the ascarids, DNA is lost only in pre-somatic cells during early embryogenesis, leading to a reduced somatic genome compared to the intact germ cell genome. Comparative genome analysis has provided information on the retained vs. eliminated sequences, DNA breaks, a full chromosome view on DNA elimination, and the evolutionary conservation of DNA elimination among ascarids. These studies have revealed novel insights into the functions and mechanisms of DNA elimination and provided a reference for in-depth molecular analysis of DNA elimination. Here, I describe the genomics methods we used to study programmed DNA elimination, focusing on the parasitic nematode Ascaris.
    MeSH term(s) Animals ; Chromosomes ; DNA ; Genome ; Germ Cells ; Nematoda/genetics
    Chemical Substances DNA (9007-49-2)
    Language English
    Publishing date 2021-07-27
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-1681-9_14
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: An ancient defense mechanism: Conservation of gasdermin-mediated pyroptosis.

    Wang, Chengliang / Ruan, Jianbin

    PLoS biology

    2023  Volume 21, Issue 5, Page(s) e3002103

    Abstract: The gasdermins are a family of pore-forming proteins involved in various cellular processes such as cell death and inflammation. A new study in PLOS Biology explores the evolutionary history of gasdermins across metazoans, highlighting the conservation ... ...

    Abstract The gasdermins are a family of pore-forming proteins involved in various cellular processes such as cell death and inflammation. A new study in PLOS Biology explores the evolutionary history of gasdermins across metazoans, highlighting the conservation and divergence of gasdermin E.
    MeSH term(s) Animals ; Pyroptosis/physiology ; Lancelets/metabolism ; Gasdermins ; Neoplasm Proteins/metabolism ; Defense Mechanisms
    Chemical Substances Gasdermins ; Neoplasm Proteins
    Language English
    Publishing date 2023-05-04
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2126776-5
    ISSN 1545-7885 ; 1544-9173
    ISSN (online) 1545-7885
    ISSN 1544-9173
    DOI 10.1371/journal.pbio.3002103
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6193: Show issues Location:
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  6. Article ; Online: Programmed DNA elimination in the parasitic nematode Ascaris.

    Brandon Estrem / Jianbin Wang

    PLoS Pathogens, Vol 19, Iss 2, p e

    2023  Volume 1011087

    Abstract: In most organisms, the whole genome is maintained throughout the life span. However, exceptions occur in some species where the genome is reduced during development through a process known as programmed DNA elimination (PDE). In the human and pig ... ...

    Abstract In most organisms, the whole genome is maintained throughout the life span. However, exceptions occur in some species where the genome is reduced during development through a process known as programmed DNA elimination (PDE). In the human and pig parasite Ascaris, PDE occurs during the 4 to 16 cell stages of embryogenesis, when germline chromosomes are fragmented and specific DNA sequences are reproducibly lost in all somatic cells. PDE was identified in Ascaris over 120 years ago, but little was known about its molecular details until recently. Genome sequencing revealed that approximately 1,000 germline-expressed genes are eliminated in Ascaris, suggesting PDE is a gene silencing mechanism. All germline chromosome ends are removed and remodeled during PDE. In addition, PDE increases the number of chromosomes in the somatic genome by splitting many germline chromosomes. Comparative genomics indicates that these germline chromosomes arose from fusion events. PDE separates these chromosomes at the fusion sites. These observations indicate that PDE plays a role in chromosome karyotype and evolution. Furthermore, comparative analysis of PDE in other parasitic and free-living nematodes illustrates conserved features of PDE, suggesting it has important biological significance. We summarize what is known about PDE in Ascaris and its relatives. We also discuss other potential functions, mechanisms, and the evolution of PDE in these parasites of humans and animals of veterinary importance.
    Keywords Immunologic diseases. Allergy ; RC581-607 ; Biology (General) ; QH301-705.5
    Subject code 572
    Language English
    Publishing date 2023-02-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: The impact of Russia–Ukraine war on crude oil prices

    Qi Zhang / Yi Hu / Jianbin Jiao / Shouyang Wang

    Humanities & Social Sciences Communications, Vol 11, Iss 1, Pp 1-

    an EMC framework

    2024  Volume 12

    Abstract: Abstract As the second-largest oil producer and natural gas exporter, Russia’s war with Ukraine has severely impacted the energy market. To what extent has the war influenced crude oil prices, and has it altered the long-term dynamics of oil prices? An ... ...

    Abstract Abstract As the second-largest oil producer and natural gas exporter, Russia’s war with Ukraine has severely impacted the energy market. To what extent has the war influenced crude oil prices, and has it altered the long-term dynamics of oil prices? An objective analysis of the effects of the Russia–Ukraine war on the crude oil market can assist relevant entities in developing both short-term emergency strategies and long-term response plans. This study establishes an analytical framework of the event analysis method based on multiresolution causality testing (EMC). The results of the multiresolution causality testing reveal a significant one-way causality between the Russia–Ukraine war and crude oil prices. Afterward, using the event analysis based on variational mode decomposition (VMD), from October 1, 2021, to August 25, 2022, as the event window, we found that the war and its chain events caused the West Texas Intermediate (WTI) crude oil prices to increase by $37.14, a 52.33% surge, and the Brent crude oil price to rise by $41.49, a 56.33% increase. During the event window, the Russia–Ukraine war can account for 70.72% and 73.62% of the fluctuation in WTI and Brent crude oil prices, respectively. Furthermore, the war amplified oil price volatility and fundamentally altered the trend of crude oil prices. Consequently, this study proposes four recommendations: the establishment of an emergency management mechanism for the oil market, the diversification of oil and gas imports by energy-importing countries, the steady advancement of energy transformation, and the judicious use of financial instruments by enterprises to hedge risks.
    Keywords History of scholarship and learning. The humanities ; AZ20-999 ; Social Sciences ; H
    Subject code 339
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Springer Nature
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: End resection and telomere healing of DNA double-strand breaks during nematode programmed DNA elimination.

    Estrem, Brandon / Davis, Richard E / Wang, Jianbin

    bioRxiv : the preprint server for biology

    2024  

    Abstract: Most DNA double-strand breaks (DSBs) are harmful to genome integrity. However, some forms of DSBs are essential to biological processes, such as meiotic recombination and V(D)J recombination. DSBs are also required for programmed DNA elimination (PDE) in ...

    Abstract Most DNA double-strand breaks (DSBs) are harmful to genome integrity. However, some forms of DSBs are essential to biological processes, such as meiotic recombination and V(D)J recombination. DSBs are also required for programmed DNA elimination (PDE) in ciliates and nematodes. In nematodes, the DSBs are healed with telomere addition. While telomere addition sites have been well-characterized, little is known regarding the DSBs that fragment nematode chromosomes. Here, we used embryos from the nematode
    Language English
    Publishing date 2024-03-16
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2024.03.15.585292
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  9. Article ; Online: Ent

    Wang, Jianbin / Liu, Rongxin / Chen, Hao / Chen, Anqi / Chen, Li

    Natural product research

    2023  , Page(s) 1–6

    Abstract: ... ...

    Abstract Ent
    Language English
    Publishing date 2023-11-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2023.2287177
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  10. Article ; Online: The novel HLA-C*03:94:02 allele identified by next-generation sequencing in a Chinese individual.

    Sun, Yamin / Wang, Ziqing / Kang, Yiqing / Li, Jianbin / Liu, Zheng

    HLA

    2024  Volume 103, Issue 4, Page(s) e15453

    Abstract: HLA-C*03:94:02 differs from HLA-C*03:94:01 by a single nucleotide substitution in exon 2 (codon 17 GGA->GGG). ...

    Abstract HLA-C*03:94:02 differs from HLA-C*03:94:01 by a single nucleotide substitution in exon 2 (codon 17 GGA->GGG).
    MeSH term(s) Humans ; HLA-C Antigens/genetics ; Alleles ; Genes, MHC Class I ; High-Throughput Nucleotide Sequencing ; China
    Chemical Substances HLA-C Antigens
    Language English
    Publishing date 2024-04-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2845111-9
    ISSN 2059-2310 ; 2059-2302
    ISSN (online) 2059-2310
    ISSN 2059-2302
    DOI 10.1111/tan.15453
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 661: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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