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  1. Article ; Online: Timing of Revascularization in Patients With Acute Coronary Syndrome: Why Is Earlier Better?

    Schneider, David J

    The American journal of cardiology

    2024  

    Language English
    Publishing date 2024-04-23
    Publishing country United States
    Document type Editorial
    ZDB-ID 80014-4
    ISSN 1879-1913 ; 0002-9149
    ISSN (online) 1879-1913
    ISSN 0002-9149
    DOI 10.1016/j.amjcard.2024.04.031
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  2. Article ; Online: Plasma Soluble Glycoprotein VI: A Biomarker of Bleeding.

    Schneider, David J

    Thrombosis and haemostasis

    2023  Volume 124, Issue 4, Page(s) 307–309

    MeSH term(s) Humans ; Platelet Membrane Glycoproteins ; Hemorrhage ; Biomarkers
    Chemical Substances Platelet Membrane Glycoproteins ; Biomarkers
    Language English
    Publishing date 2023-08-24
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 518294-3
    ISSN 2567-689X ; 0340-6245
    ISSN (online) 2567-689X
    ISSN 0340-6245
    DOI 10.1055/a-2160-0368
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 433: Show issues

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  3. Article ; Online: Effective and Safe Transition Between Intravenous and Oral P2Y

    Schneider, David J

    JACC. Cardiovascular interventions

    2023  Volume 16, Issue 20, Page(s) 2540–2541

    MeSH term(s) Humans ; Treatment Outcome ; Platelet Aggregation Inhibitors ; Ticagrelor ; Purinergic P2Y Receptor Antagonists/adverse effects ; Receptors, Purinergic P2Y12
    Chemical Substances Platelet Aggregation Inhibitors ; Ticagrelor (GLH0314RVC) ; Purinergic P2Y Receptor Antagonists ; Receptors, Purinergic P2Y12
    Language English
    Publishing date 2023-09-14
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2452157-7
    ISSN 1876-7605 ; 1936-8798
    ISSN (online) 1876-7605
    ISSN 1936-8798
    DOI 10.1016/j.jcin.2023.08.045
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  4. Book ; Thesis: Bestimmung pharmakokinetischer Eigenschaften von 4-Fluoramphetamin in menschlichem Blutserum, Speichel und Urin

    Schneider, David

    2020  

    Institution Goethe-Universität Frankfurt am Main
    Author's details vorgelegt von David Schneider aus Troisdorf
    Language German
    Size V, 60 Seiten, Diagramme, 21 cm
    Publishing place Frankfurt am Main
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Johann Wolfgang Goethe-Universität Frankfurt am Main, 2020
    Note Zusammenfassung auf Deutsch und Englisch ; Literaturverzeichnis: Seite 53-56
    HBZ-ID HT020931416
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2021 D 281 order for loan Magazin

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  5. Article: Plasma Soluble Glycoprotein VI: A Biomarker of Bleeding

    Schneider, David J.

    Thrombosis and Haemostasis

    2023  Volume 124, Issue 04, Page(s) 307–309

    Language English
    Publishing date 2023-08-24
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 518294-3
    ISSN 2567-689X ; 0340-6245
    ISSN (online) 2567-689X
    ISSN 0340-6245
    DOI 10.1055/a-2160-0368
    Database Thieme publisher's database

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  6. Article: Stimulus-specific prediction error neurons in mouse auditory cortex.

    Audette, Nicholas J / Schneider, David M

    bioRxiv : the preprint server for biology

    2023  

    Abstract: Comparing expectation with experience is an important neural computation performed throughout the brain and is a hallmark of predictive processing. Experiments that alter the sensory outcome of an animal's behavior reveal enhanced neural responses to ... ...

    Abstract Comparing expectation with experience is an important neural computation performed throughout the brain and is a hallmark of predictive processing. Experiments that alter the sensory outcome of an animal's behavior reveal enhanced neural responses to unexpected self-generated stimuli, indicating that populations of neurons in sensory cortex may reflect prediction errors - mismatches between expectation and experience. However, enhanced neural responses to self-generated stimuli could also arise through non-predictive mechanisms, such as the movement-based facilitation of a neuron's inherent sound responses. If sensory prediction error neurons exist in sensory cortex, it is unknown whether they manifest as general error responses, or respond with specificity to errors in distinct stimulus dimensions. To answer these questions, we trained mice to expect the outcome of a simple sound-generating behavior and recorded auditory cortex activity as mice heard either the expected sound or sounds that deviated from expectation in one of multiple distinct dimensions. Our data reveal that the auditory cortex learns to suppress responses to self-generated sounds along multiple acoustic dimensions simultaneously. We identify a distinct population of auditory cortex neurons that are not responsive to passive sounds or to the expected sound but that explicitly encode prediction errors. These prediction error neurons are abundant only in animals with a learned motor-sensory expectation, and encode one or two specific violations rather than a generic error signal.
    Language English
    Publishing date 2023-05-01
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.01.06.523032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Stimulus-Specific Prediction Error Neurons in Mouse Auditory Cortex.

    Audette, Nicholas J / Schneider, David M

    The Journal of neuroscience : the official journal of the Society for Neuroscience

    2023  Volume 43, Issue 43, Page(s) 7119–7129

    Abstract: Comparing expectation with experience is an important neural computation performed throughout the brain and is a hallmark of predictive processing. Experiments that alter the sensory outcome of an animal's behavior reveal enhanced neural responses to ... ...

    Abstract Comparing expectation with experience is an important neural computation performed throughout the brain and is a hallmark of predictive processing. Experiments that alter the sensory outcome of an animal's behavior reveal enhanced neural responses to unexpected self-generated stimuli, indicating that populations of neurons in sensory cortex may reflect prediction errors (PEs), mismatches between expectation and experience. However, enhanced neural responses to self-generated stimuli could also arise through nonpredictive mechanisms, such as the movement-based facilitation of a neuron's inherent sound responses. If sensory prediction error neurons exist in sensory cortex, it is unknown whether they manifest as general error responses, or respond with specificity to errors in distinct stimulus dimensions. To answer these questions, we trained mice of either sex to expect the outcome of a simple sound-generating behavior and recorded auditory cortex activity as mice heard either the expected sound or sounds that deviated from expectation in one of multiple distinct dimensions. Our data reveal that the auditory cortex learns to suppress responses to self-generated sounds along multiple acoustic dimensions simultaneously. We identify a distinct population of auditory cortex neurons that are not responsive to passive sounds or to the expected sound but that encode prediction errors. These prediction error neurons are abundant only in animals with a learned motor-sensory expectation, and encode one or two specific violations rather than a generic error signal. Together, these findings reveal that cortical predictions about self-generated sounds have specificity in multiple simultaneous dimensions and that cortical prediction error neurons encode specific violations from expectation.
    MeSH term(s) Animals ; Mice ; Auditory Cortex/physiology ; Auditory Perception/physiology ; Acoustic Stimulation/methods ; Sensory Receptor Cells ; Sound
    Language English
    Publishing date 2023-09-12
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 604637-x
    ISSN 1529-2401 ; 0270-6474
    ISSN (online) 1529-2401
    ISSN 0270-6474
    DOI 10.1523/JNEUROSCI.0512-23.2023
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  8. Article ; Online: Platelet Function Testing and Clinical Outcomes: Connecting the Dots.

    Schneider, David J

    JACC. Basic to translational science

    2019  Volume 4, Issue 7, Page(s) 776–777

    Language English
    Publishing date 2019-11-25
    Publishing country United States
    Document type Editorial
    ISSN 2452-302X
    ISSN (online) 2452-302X
    DOI 10.1016/j.jacbts.2019.09.007
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  9. Article ; Online: Platelet FcγRIIa expression in patients with stable coronary artery disease.

    Adamian, Robert / McCleary, Paul / Sharma, Toishi / Schneider, David J

    The Journal of invasive cardiology

    2024  Volume 36, Issue 2

    Abstract: Objectives: FcɣRIIa amplifies platelet activation and greater expression increases platelet reactivity. In patients with myocardial infarction (MI), high platelet FcɣRIIa identifies patients with an approximately 4-fold greater risk of MI, stroke, and ... ...

    Abstract Objectives: FcɣRIIa amplifies platelet activation and greater expression increases platelet reactivity. In patients with myocardial infarction (MI), high platelet FcɣRIIa identifies patients with an approximately 4-fold greater risk of MI, stroke, and death. We compared platelet FcɣRIIa in 2 groups: (1) patients who had not had an MI in the previous year and were undergoing cardiac catheterization and percutaneous coronary intervention (PCI) labeled as stable coronary artery disease (CAD), and (2) previously obtained results in patients with MI (n = 197).
    Methods: Patients undergoing cardiac catheterization and PCI were enrolled. FcɣRIIa expression was quantified with the use of flow cytometry. Comparisons were made with Mann-Whitney Rank Sum Test and Chi Squared analysis. Significance was defined as P less than .05.
    Results: Compared to patients with MI, patients with stable CAD (n = 49) were older (70 ± 9 years vs 63 ± 12 years) and were more likely to have had prior MI (43% vs 23%), prior revascularization (62% vs 33%), diabetes (35% vs 24%), and hypertension (98% vs 66%). In patients with stable CAD, platelet FcɣRIIa was, on average, lower than that seen in patients with acute MI (9746 ± 4316 vs 11 479 ± 2405 molecules/platelet, P less than .001). Patients with stable CAD exhibited a range of platelet FcɣRIIa (~4500 to ~27 000 molecules/platelet) similar to that seen in acute MI patients (~6500 to ~30 000 molecules/platelet).
    Conclusions: Compared to patients with MI, patients with stable CAD had, on average, lower platelet FcɣRIIa. However, the range of platelet FcɣRIIa was similar to that seen in patients with MI. These results support future studies designed to assess the prognostic implications of platelet FcɣRIIa in patients with stable CAD.
    MeSH term(s) Humans ; Coronary Artery Disease/diagnosis ; Coronary Artery Disease/surgery ; Percutaneous Coronary Intervention ; Treatment Outcome ; Myocardial Infarction/diagnosis ; Receptors, IgG
    Chemical Substances Fc gamma receptor IIA ; Receptors, IgG
    Language English
    Publishing date 2024-02-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1154372-3
    ISSN 1557-2501 ; 1042-3931
    ISSN (online) 1557-2501
    ISSN 1042-3931
    DOI 10.25270/jic/23.00247
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  10. Book ; Conference proceedings ; Online: Paleomagnetism of ODP Leg 115 sediments, supplementary data to: Schneider, David A; Kent, Dennis V (1990): Paleomagnetism of Leg 115 sediments: implications for Neogene magnetostratigraphy and paleolatitude of the R?union Hotspot. In: Duncan, RA; Backmann, J; Peterson, LC; et al. (eds.), Proceedings of the Ocean Drilling Program, Scientific Results, College Station, TX (Ocean Drilling Program), 115, 717-736

    Schneider, David A / Kent, Dennis V

    1990  

    Abstract: Ocean Drilling Program Leg 115 was designed to study Neogene sedimentation history in the western Indian Ocean Basin as well as the Cenozoic evolution of the Reunion hotspot. We describe the paleomagnetic analysis of the sediments recovered on this leg, ... ...

    Abstract Ocean Drilling Program Leg 115 was designed to study Neogene sedimentation history in the western Indian Ocean Basin as well as the Cenozoic evolution of the Reunion hotspot. We describe the paleomagnetic analysis of the sediments recovered on this leg, focusing on the sites that provided the most readily interpretable data: Sites 706, 709, 710, and 711. Sediments from Site 706 show no reversals but appear to give a reliable reversed polarity primary direction, judged on the basis of the demagnetization behavior of individual samples as well as from the results of a fold test formulated by comparing the two holes drilled at this site. Magnetic polarity stratigraphy in sediments from Site 709 can be deduced in two limited sections of Pliocene-Pleistocene and Oligocene-Miocene age. Sediments recovered at Site 710 (and, to a lesser extent, Site 711) render a relatively continuous magnetic polarity stratigraphy that spans most of the Neogene and adds significantly to the body of data available to address problems in Miocene geochronology.
    In addition to these magnetostratigraphic results, the paleomagnetism of these sediments can be used to determine paleolatitude. Using the most reliable inclination measurements from Sites 706, 710, and 711, we compared paleomagnetic estimates of paleolatitude with estimates derived from a hotspot-based absolute plate motion model. Our data, which covers the interval since 33 Ma, shows that paleolatitudes calculated with the geocentric axial dipole assumption are in general accord with the hotspot predictions. However, a correction for the long-term nondipole field brings the paleomagnetic results into even better agreement with plate motions that are based on the fixity of African hotspots.
    Language English
    Dates of publication 1990-9999
    Size Online-Ressource
    Publisher PANGAEA - Data Publisher for Earth & Environmental Science
    Publishing place Bremen/Bremerhaven
    Document type Book ; Conference proceedings ; Online
    Note This dataset is supplement to doi:10.2973/odp.proc.sr.115.197.1990
    DOI 10.1594/PANGAEA.758320
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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