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  1. Book: Practical Transfusion Medicine

    Roberts, David J. / Yazer, Mark H. / Murphy, Michael F. / Dunbar, Nancy M.

    2022  

    Author's details About the Editors Michael F. Murphy, MD, FRCP, FRCPath, FFPath, is Professor of Blood Transfusion Medicine at the University of Oxford, and Consultant Haematologist for NHS Blood and Transplant and the Department of Haematology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK. David J. Roberts, MB, ChB, DPhil, FRCPath, is Professor of Haematology at the University of Oxford, Medical Director for Pathology for NHS Blood and Transplant and also works as a Consultant Haematologist in the Department of Haematology, John Radcliffe Hospital, Oxford, UK. Mark H. Yazer, MD is Professor of Pathology at the University of Pittsburgh, an Adjunct Professor of Clinical Immunology at the University of Southern Denmark, Odense, Denmark, and a Visiting Professor of Pathology at Tel Aviv University. His research interest is in blood use in massive bleeding. Nancy M. Dunbar, MD is Associate Professor of Pathology and Laboratory Medicine at the Geisel School of Medicine at Dartmouth and se
    Size 672 p.
    Publisher John Wiley & Sons Ltd
    Document type Book
    Note PDA Manuell_15
    Format 179 x 258 x 31
    ISBN 9781119665816 ; 1119665817
    Database PDA

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  2. Book ; Online: Magnetostratigraphic calibration of Southern Ocean diatom datums from the Eocene-Oligocene of Kerguelen Plateau (Ocean Drilling Program sites 744 and 748), supplementary data to: Roberts, Andrew P; Bicknell, Simon J; Byatt, Joanne; Bohaty, Steven M; Florindo, Fabio; Harwood, David M (2003): Magnetostratigraphic calibration of Southern Ocean diatom datums from the Eocene-Oligocene of Kerguelen Plateau (Ocean Drilling Program sites 744 and 748). Palaeogeography, Palaeoclimatology, Palaeoecology, 198(1-2), 145-168

    Roberts, Andrew P / Bicknell, Simon J / Bohaty, Steven M / Byatt, Joanne / Florindo, Fabio / Harwood, David M

    2003  

    Abstract: Ocean Drilling Program holes 744A and 748B represent key sections for calibration of Southern Ocean Eocene-Oligocene biostratigraphic zonations. Sites 744 and 748 were above the carbonate compensation depth throughout this time interval and contain good ... ...

    Abstract Ocean Drilling Program holes 744A and 748B represent key sections for calibration of Southern Ocean Eocene-Oligocene biostratigraphic zonations. Sites 744 and 748 were above the carbonate compensation depth throughout this time interval and contain good planktonic foraminiferal, calcareous nannofossil, and diatom biostratigraphic records. In particular, the Southern Ocean diatom biostratigraphic zonation for the Oligocene critically hinges on calibration of these two holes. Previous low-resolution magnetostratigraphic studies at these sites were hampered by limited sampling and technical difficulties, which prompted our high-resolution reinvestigation of the magnetostratigraphy. Magnetic polarity zonations for holes 744A and 748B were constructed after inspection of vector component plots at 1-cm stratigraphic intervals from continuous u-channel measurements. The magnetizations are generally stable and a robust polarity stratigraphy has been obtained for both holes. The increased resolution of our study and identification of persistent secondary overprints, which were not recognised in previous studies, suggests that the previously published interpretations need to be revised. Our magnetostratigraphic interpretations for both holes are constrained by foraminiferal and calcareous nannofossil datums, as well as by Sr isotope ages. We have calibrated four diatom datums, which are synchronous at the two studied sites, to the geomagnetic polarity timescale, including the first occurrence (FO) of Lisitzinia ornata (27.8 Ma), the FO of Rocella vigilans var. B (27.8 Ma), the FO of Cavitatus jouseanus (30.9 Ma) and the FO of Rhizosolenia oligocaenica (33.8 Ma). The synchroneity of these datums suggests that diatom biostratigraphy has considerable potential for Palaeogene biostratigraphic correlation in the Southern Ocean. Although the ages of some datums are obscured by an unconformity in Hole 744A, our age model from Hole 748B suggests age estimates for the last common occurrence of Rocella vigilans var. A (~29.0 Ma), the FO of Rocella vigilans var. A (30.0 Ma) and the FO of Rhizosolenia antarctica (33.2 Ma). It should also be noted that the last occurrence of the calcareous nannofossil Chiasmolithus altus occurs in Chron C8r rather than C8n in our revised magnetostratigraphic interpretation, which indicates that this datum is not diachronous between low and mid latitudes as had previously been suggested. Significant unconformities are documented in both holes, in the middle Oligocene and in the middle late Oligocene, respectively, which probably resulted from periods of enhanced circumpolar deep-water circulation.
    Language English
    Dates of publication 2003-9999
    Size Online-Ressource
    Publisher PANGAEA - Data Publisher for Earth & Environmental Science
    Publishing place Bremen/Bremerhaven
    Document type Book ; Online
    Note This dataset is supplement to doi:10.1016/S0031-0182(03)00397-3
    DOI 10.1594/PANGAEA.695407
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  3. Book ; Online: Rare-earth element concentration of anhydrite vein separated from ODP Site 1188 (Table 2), supplementary data to: Bach, Wolfgang; Roberts, Stephen; Vanko, David A; Binns, Raymond A; Yeats, Chris J; Craddock, Paul R; Humphris, Susan E (2003): Controls of fluid chemistry and complexation on rare earth element contents of anhydrite from the PACMANUS subseafloor hydrothermal system, Manus Basin, Papua New Guinea. Mineralium Deposita, 38(8), 916-935

    Bach, Wolfgang / Binns, Raymond A / Craddock, Paul R / Humphris, Susan E / Roberts, Stephen / Vanko, David A / Yeats, Chris J

    2003  

    Abstract: Ocean Drilling Program (ODP) leg 193 successfully drilled four deep holes (126 to 386 m) into basement underlying the active dacite-hosted Pacmanus hydrothermal field in the eastern Manus Basin. Anhydrite is abundant in the drill core material, filling ... ...

    Abstract Ocean Drilling Program (ODP) leg 193 successfully drilled four deep holes (126 to 386 m) into basement underlying the active dacite-hosted Pacmanus hydrothermal field in the eastern Manus Basin. Anhydrite is abundant in the drill core material, filling veins and vesicles, cementing breccias, and occasionally replacing igneous material. We report rare-earth element (REE) contents of anhydrite from a site of diffuse venting (Site 1188) which show extreme variability, in terms of both absolute concentrations (e.g., 0.08-28.3 ppm Nd) and pattern shape (LaN/SmN=0.08-3.78, SmN/YbN=0.48-23.1, Eu/Eu*=0.59-6.1). The range of REE patterns in anhydrite includes enrichments in the middle and heavy REEs and variable Eu anomalies. The patterns differ markedly from those of anhydrite recovered during ODP Leg 158 from the TAG hydrothermal system at the Mid-Atlantic Ridge which display uniform LREE-enriched patterns with positive Eu anomalies, very similar to TAG vent fluid patterns. As the system is active, the host-rock composition is uniform, and the anhydrite veins appear to relate to the same hydrothermal stage, we can rule out predominant host-rock and transport control. Instead, we propose that the variation in REE content reflects waxing and waning input of magmatic volatiles (HF, SO2) and variable complexation of REEs in the fluids. REE speciation calculations suggest that increased fluoride and possibly sulfate concentrations at Pacmanus may affect REE complexation in fluids, whereas at TAG only chloride and hydroxide complexes play a significant role. The majority of the anhydrites do not show positive Eu anomalies, suggesting that the fluids were more oxidizing than in typical mid-ocean ridge hydrothermal systems. We use other hydrothermal fluids from the Manus Basin (Vienna Woods and Desmos), which bracket the Pacmanus fluids in terms of acidity and ligand concentrations, to examine the dependence of REE complexation on fluid composition. Geochemical modeling reveals that under the prevailing conditions at Pacmanus (pH=3.5, T=250-300 ?C), Eu oxidation state and the relative importance of fluoride versus chloride complexing are very sensitive to small variations in oxygen fugacity, temperature, and pH. Patterns with extreme mid-REE enrichment may reflect speciation effects (free-ion abundance) coupled with crystal chemical control. We conclude that the great variability in REE concentrations and pattern shape is likely due to variable fluid composition and REE complexation in the fluids.
    Language English
    Dates of publication 2003-9999
    Size Online-Ressource
    Publisher PANGAEA - Data Publisher for Earth & Environmental Science
    Publishing place Bremen/Bremerhaven
    Document type Book ; Online
    Note This dataset is supplement to doi:10.1007/s00126-002-0325-0
    DOI 10.1594/PANGAEA.666862
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  4. Book ; Online: Chronostratigraphy of sediment core CRP-2/2A (Table 1), supplementary data to: Wilson, Gary S; Bohaty, Steven M; Fielding, Christopher R; Florindo, Fabio; Hannah, Mike J; Harwood, David M; McIntosh, WC; Naish, Tim R; Roberts, Andrew P; Sagnotti, Leo; Scherer, Reed P; Strong, C Percy; Versub, KL; Villa, Giuliana; Watkins, David K; Webb, Peter-Noel; Woolfe, Ken (2000): Chronostratigraphy of CRP-2/2A, Victoria Land Basin, Antarctica. Terra Antartica, 7(4), 647-654

    Wilson, Gary S / Bohaty, Steven M / Fielding, Christopher R / Florindo, Fabio / Hannah, Mike J / Harwood, David M / McIntosh, WC / Naish, Tim R / Roberts, Andrew P / al., et

    2000  

    Abstract: The 624.15 m glaciomarine sedimentary succession recovered in the CRP-2/2A drillcore comprises lower Oligocene (

    Abstract The 624.15 m glaciomarine sedimentary succession recovered in the CRP-2/2A drillcore comprises lower Oligocene (<c. 31 Ma) to lower Miocene (18.5 Ma) strata that are overlain by a thin succession of Pliocene and Pleistocene strata. The age model for the CRP-2/2A drillhole, as presented in this paper, is based on combined microfossil biostratigraphy. 40Ar/39Ar age on volcanic material, 87Sr/86Sr analyses on mollusc shells, and correlation of a magnetic polarity zonation to the magnetic polarity time scale (MPTS). Between 25.92 and 109.05 metres below sea floor (mbsf), several alternative correlations to the MPTS are possible, all of which suggest that sediment accumulation rates averaged ~180 m/m.y. between unconformities, although actual sedimentation rates may have been higher. Between 109.05 and 306.65 mbsf, the age model is straightforward and average sedimentation rates were much higher (>1000 m/m.y.). Between 306.65 mbsf and the bottom of the drillcore (624.15 mbsf), fewer datums are available to constrain the age model and unique correlation with the MPTS is not possible, although high average sediment accumulation rates are likely. A significant unconformity is identified at 306.65 mbsf, which may represent as much as 5 m.y. of missing time. Additional unconformities at 25.92 and 130.27 mbsf account for c. 16 and 2.5 m.y. of missing time, respectively. The Oligocene-lower Miocene interval documented in the CRP-2/2A drillcore spans about 13 million years, however, it is possible that more time is missing in sequence-bounding unconformities than is represented in the stratigraphic record recovered in the CRP-2/2A drillcore.
    Language English
    Dates of publication 2000-9999
    Size Online-Ressource
    Publisher PANGAEA - Data Publisher for Earth & Environmental Science
    Publishing place Bremen/Bremerhaven
    Document type Book ; Online
    Note This dataset is supplement to hdl:10013/epic.28244.d001
    DOI 10.1594/PANGAEA.189249
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  5. Book: Global hematology

    Roberts, David J.

    (Hematology/oncology clinics of North America ; volume 30, number 2 (April 2016))

    2016  

    Author's details editors David J. Roberts, Sir David J. Weatherall
    Series title Hematology/oncology clinics of North America ; volume 30, number 2 (April 2016)
    Hematology, oncology clinics of North America
    Collection Hematology, oncology clinics of North America
    Language English
    Size xiv Seiten, Seite 234-527, Illustrationen
    Publisher Elsevier
    Publishing place Philadelphia, Pennsylvania
    Publishing country United States
    Document type Book
    HBZ-ID HT019011957
    ISBN 978-0-323-41756-3 ; 0-323-41756-6
    Database Catalogue ZB MED Medicine, Health

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  6. Article ; Online: Blood services, COVID-19 and lessons being learnt: the past pandemic is not over, it's not even past.

    Roberts, David J

    Transfusion medicine (Oxford, England)

    2023  Volume 33, Issue 1, Page(s) 3–5

    MeSH term(s) Humans ; COVID-19 ; Pandemics ; SARS-CoV-2
    Language English
    Publishing date 2023-02-23
    Publishing country England
    Document type Editorial
    ZDB-ID 1067989-3
    ISSN 1365-3148 ; 0958-7578
    ISSN (online) 1365-3148
    ISSN 0958-7578
    DOI 10.1111/tme.12959
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: 2021: That was the year that was.

    Roberts, David J

    Transfusion medicine (Oxford, England)

    2021  Volume 31, Issue 6, Page(s) 393–394

    Language English
    Publishing date 2021-12-28
    Publishing country England
    Document type Editorial
    ZDB-ID 1067989-3
    ISSN 1365-3148 ; 0958-7578
    ISSN (online) 1365-3148
    ISSN 0958-7578
    DOI 10.1111/tme.12847
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: 2020: A year we will remember.

    Roberts, David J

    Transfusion medicine (Oxford, England)

    2021  Volume 30, Issue 6, Page(s) 416–417

    Language English
    Publishing date 2021-01-05
    Publishing country England
    Document type Editorial
    ZDB-ID 1067989-3
    ISSN 1365-3148 ; 0958-7578
    ISSN (online) 1365-3148
    ISSN 0958-7578
    DOI 10.1111/tme.12751
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Idiopathic infantile hypercalcaemia (IIH) resulting from a loss-of-function mutation in the CYP24A1 gene in a young high-performance athlete: A case report with a literature review of adult presentations.

    Rodríguez, Alexander J / Roberts, David J

    Clinical endocrinology

    2023  Volume 99, Issue 4, Page(s) 355–360

    MeSH term(s) Adult ; Humans ; Hypercalcemia/genetics ; Vitamin D ; Vitamin D3 24-Hydroxylase/genetics ; Loss of Function Mutation
    Chemical Substances CYP24A1 protein, human (EC 1.14.15.16) ; Vitamin D (1406-16-2) ; Vitamin D3 24-Hydroxylase (EC 1.14.15.16)
    Language English
    Publishing date 2023-07-27
    Publishing country England
    Document type Review ; Case Reports
    ZDB-ID 121745-8
    ISSN 1365-2265 ; 0300-0664
    ISSN (online) 1365-2265
    ISSN 0300-0664
    DOI 10.1111/cen.14954
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: A patient with neuropathy and ataxia: what do I have to consider?

    Roberts, Leslie J / Szmulewicz, David J

    Current opinion in neurology

    2023  Volume 36, Issue 5, Page(s) 382–387

    Abstract: Purpose of review: An increasing number of peripheral neuro(no)pathies are identified as involving other components of the neurological system, particularly those that further impair balance. Here we aim to outline an evidence-based approach to the ... ...

    Abstract Purpose of review: An increasing number of peripheral neuro(no)pathies are identified as involving other components of the neurological system, particularly those that further impair balance. Here we aim to outline an evidence-based approach to the diagnosis of patients who present with a somatosensory disorder which also involves at least one other area of neurological impairment such as the vestibular, auditory, or cerebellar systems.
    Recent findings: Detailed objective investigation of patients who present with sensory impairment, particularly where the degree of imbalance is greater than would be expected, aids the accurate diagnosis of genetic, autoimmune, metabolic, and toxic neurological disease.
    Summary: Diagnosis and management of complex somatosensory disorders benefit from investigation which extends beyond the presenting sensory impairment.
    MeSH term(s) Humans ; Ataxia/diagnosis ; Ataxia/therapy ; Peripheral Nervous System Diseases/diagnosis ; Peripheral Nervous System Diseases/therapy ; Cerebellum ; Neurology ; Vestibule, Labyrinth
    Language English
    Publishing date 2023-08-17
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 1182686-1
    ISSN 1473-6551 ; 1350-7540
    ISSN (online) 1473-6551
    ISSN 1350-7540
    DOI 10.1097/WCO.0000000000001200
    Database MEDical Literature Analysis and Retrieval System OnLINE

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