LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 55

Search options

  1. Article: Silent choker: Unveiling tracheal stenosis as an atypical manifestation of mucormycosis.

    Kaliya, Mehul G / Rathod, Mittal C / Deokar, Kunal K / Singhal, Sanjay

    Lung India : official organ of Indian Chest Society

    2024  Volume 41, Issue 1, Page(s) 63–66

    Abstract: Airway mucormycosis is a fatal opportunistic infection typically seen in immunocompromised individuals. In this case report, we present an unusual instance of tracheal stenosis in a patient with diabetes mellitus who had recently recovered from ... ...

    Abstract Airway mucormycosis is a fatal opportunistic infection typically seen in immunocompromised individuals. In this case report, we present an unusual instance of tracheal stenosis in a patient with diabetes mellitus who had recently recovered from coronavirus 2019 (COVID-19). Our patient was a 69-year-old male with poorly controlled type-II diabetes mellitus, on oral hypoglycemic agents, who had successfully completed treatment for COVID-19. Approximately one month later, he developed a cough, fever and breathlessness. Several factors, including advanced age, history of smoking and tobacco chewing, the nodular appearance of the trachea on bronchoscopy, hypermetabolic wall of the trachea on positron emission tomography scan and dysplasia on biopsy, initially raised suspicion of malignancy. However, repeated biopsies from multiple sites confirmed the diagnosis of tracheal mucormycosis. The patient was treated with amphotericin-B and posaconazole. We extensively reviewed the literature and found only 14 reported cases to discuss compared to ours.
    Language English
    Publishing date 2024-01-01
    Publishing country India
    Document type Journal Article
    ZDB-ID 2410801-7
    ISSN 0974-598X ; 0970-2113
    ISSN (online) 0974-598X
    ISSN 0970-2113
    DOI 10.4103/lungindia.lungindia_250_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Nephrotic syndrome leading to recurrent pulmonary embolism: A report of two cases.

    Agarwal, Mehul / Sharma, Krishna Kumar / Bharti, Neha / Deokar, Kunal

    Acta bio-medica : Atenei Parmensis

    2022  Volume 93, Issue 1, Page(s) e2022024

    Abstract: ...

    Abstract .
    MeSH term(s) Female ; Humans ; Male ; Nephrotic Syndrome/complications ; Pulmonary Embolism/complications ; Pulmonary Embolism/diagnostic imaging
    Language English
    Publishing date 2022-03-14
    Publishing country Italy
    Document type Case Reports ; Journal Article
    ZDB-ID 2114240-3
    ISSN 2531-6745 ; 0392-4203
    ISSN (online) 2531-6745
    ISSN 0392-4203
    DOI 10.23750/abm.v93i1.10762
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article: Is Rivaroxaban Superior to Enoxaparin for Thromboprophylaxis in Hospitalized Patients of COVID-19?`.

    Deokar, Kunal / Kaliya, Mehul / Vachhani, Karan / Singhal, Sanjay / Parekh, Aneri

    The Journal of the Association of Physicians of India

    2022  Volume 70, Issue 9, Page(s) 11–12

    MeSH term(s) Anticoagulants/therapeutic use ; COVID-19 ; Enoxaparin/therapeutic use ; Humans ; Rivaroxaban/therapeutic use ; Venous Thromboembolism/drug therapy ; Venous Thromboembolism/prevention & control
    Chemical Substances Anticoagulants ; Enoxaparin ; Rivaroxaban (9NDF7JZ4M3)
    Language English
    Publishing date 2022-09-07
    Publishing country India
    Document type Letter ; Comment
    ZDB-ID 800766-4
    ISSN 0004-5772
    ISSN 0004-5772
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article: Post partum

    Deokar, Kunal / Niwas, Ram / Chawla, Gopal / Chauhan, Nishant

    publication RETRACTED

    Breathe (Sheffield, England)

    2020  Volume 16, Issue 2, Page(s) 190366

    Abstract: Management of pulmonary embolism ... ...

    Abstract Management of pulmonary embolism in
    Language English
    Publishing date 2020-12-10
    Publishing country England
    Document type Journal Article ; Retracted Publication
    ZDB-ID 2562899-9
    ISSN 2073-4735 ; 1810-6838
    ISSN (online) 2073-4735
    ISSN 1810-6838
    DOI 10.1183/20734735.0366-2019
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article: Ocular manifestations of common pulmonary diseases: a narrative review.

    Singh, Mamta / Deokar, Kunal / Sinha, Bibhuti Prassan / Keena, Monika / Desai, Govind

    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace

    2023  Volume 94, Issue 1

    Abstract: Several pulmonary disorders can cause ocular involvement. Understanding these manifestations is critical for early diagnosis and treatment. Hence, we set out to examine the most common ocular manifestations of asthma, chronic obstructive pulmonary ... ...

    Abstract Several pulmonary disorders can cause ocular involvement. Understanding these manifestations is critical for early diagnosis and treatment. Hence, we set out to examine the most common ocular manifestations of asthma, chronic obstructive pulmonary disease (COPD), sarcoidosis, obstructive sleep apnea (OSA), and lung cancer. Allergic keratoconjunctivitis and dry eye are two ocular manifestations of bronchial asthma. The inhaled corticosteroids used to treat asthma can cause cataract formation. COPD is associated with ocular microvascular changes as a result of chronic hypoxia and systemic inflammation spillover into the eyes. Its clinical significance, however, is unknown. Ocular involvement is common in sarcoidosis, occurring in 20% of cases of pulmonary sarcoidosis. It can affect nearly any anatomical structure of the eye. Obstructive sleep apnea has been linked to floppy eye syndrome, glaucoma, non-arteritic anterior ischemic optic neuropathy, keratoconus, retinal vein occlusion, and central serous retinopathy, according to research. However, while an association has been established, causality has yet to be established. The effect of positive airway pressure (PAP) therapy used to treat OSA on the aforementioned ocular conditions is unknown. PAP therapy can cause eye irritation and dryness. Lung cancer can affect the eyes through direct nerve invasion, ocular metastasis, or as part of a paraneoplastic syndrome. The goal of this narrative review is to raise awareness about the link between ocular and pulmonary disorders in order to aid in the early detection and treatment of these conditions.
    MeSH term(s) Humans ; Sleep Apnea, Obstructive/complications ; Sleep Apnea, Obstructive/therapy ; Sleep Apnea, Obstructive/diagnosis ; Lung Diseases/complications ; Pulmonary Disease, Chronic Obstructive/complications ; Lung Neoplasms/complications ; Asthma/complications ; Sarcoidosis/complications
    Language English
    Publishing date 2023-03-03
    Publishing country Italy
    Document type Review ; Journal Article
    ZDB-ID 1160940-0
    ISSN 1122-0643 ; 1120-0391
    ISSN 1122-0643 ; 1120-0391
    DOI 10.4081/monaldi.2023.2535
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Role of corneal collagen cross-linking in bullous keratopathy: A systematic review.

    Singh, Mamta / Sinha, Bibhuti Prassan / Mishra, Deepak / Deokar, Kunal / Bhatia, Gayatri / Upreti, Garima

    Indian journal of ophthalmology

    2023  Volume 71, Issue 5, Page(s) 1706–1717

    Abstract: Corneal cross-linking (CXL), a corneal strengthening procedure, is known to alter anterior stroma swelling behavior and is one of the treatment modalities of bullous keratopathy (BK). There are multiple studies published on the role of CXL in the ... ...

    Abstract Corneal cross-linking (CXL), a corneal strengthening procedure, is known to alter anterior stroma swelling behavior and is one of the treatment modalities of bullous keratopathy (BK). There are multiple studies published on the role of CXL in the treatment of BK. These articles had heterogeneous study population, different protocols used, and variable conclusions. This systematic review aimed to determine the role of CXL in the treatment of BK. The primary outcomes considered were changes in central corneal thickness (CCT) after 1, 3, and 6 months of CXL. The secondary outcome measures were changes in visual acuity, corneal clarity, subjective symptoms, and complications after CXL. We included randomized control trials (RCTs), observational and interventional studies, and case series with reports of more than 10 cases in this review. In RCTs, the mean pre-CXL CCT (794.0 ± 178.5 μm) in the intervention group (n = 37), decreased at 1 month (750.9 ± 154.3 μm) followed by a subsequent increase, but this difference was not significant during the 6-month follow-up (P- value 0.28, 0.82, and 0.82 at 1, 3, and 6 months, respectively). In noncomparative clinical studies (n = 188), the mean pre-CXL CCT (794.0 ± 178.5 μm) decreased at 1 month (710.9 ± 127.2 μm, P < 0.0001). Seven of the 11 articles included in the review reported no significant improvement in vision with CXL. The initial improvement in corneal clarity and clinical symptoms was not sustained. Current evidence suggests that CXL has short-term efficacy in the treatment of BK. More RCTs with high-quality evidence are needed.
    MeSH term(s) Humans ; Corneal Cross-Linking ; Photosensitizing Agents/therapeutic use ; Riboflavin/therapeutic use ; Ultraviolet Rays ; Collagen/therapeutic use ; Cross-Linking Reagents/therapeutic use ; Corneal Stroma ; Keratoconus/drug therapy ; Corneal Topography
    Chemical Substances Photosensitizing Agents ; Riboflavin (TLM2976OFR) ; Collagen (9007-34-5) ; Cross-Linking Reagents
    Language English
    Publishing date 2023-05-18
    Publishing country India
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 187392-1
    ISSN 1998-3689 ; 0301-4738
    ISSN (online) 1998-3689
    ISSN 0301-4738
    DOI 10.4103/ijo.IJO_1942_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article: Comparison of efficacy of bedaquiline and moxifloxacin in drug resistant pulmonary tuberculosis. A prospective observational study.

    Desai, Govind / Purohit, Gopal / Borana, Hemant / Deokar, Kunal / Yogi, Suresh

    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace

    2022  

    Abstract: Drug-resistant tuberculosis remains a major public health concern in many countries. We compared the efficacy and safety of bedaquiline plus optimized background regimen (Bdq+OBR) with high dose moxifloxacin and optimized background regimen (Mfx(h)+OBR) ... ...

    Abstract Drug-resistant tuberculosis remains a major public health concern in many countries. We compared the efficacy and safety of bedaquiline plus optimized background regimen (Bdq+OBR) with high dose moxifloxacin and optimized background regimen (Mfx(h)+OBR) for the treatment of patients with multidrug-resistant tuberculosis with additional resistance to fluoroquinolones. In this prospective observational study, newly diagnosed cases of multidrug-resistant tuberculosis with additional resistance to fluoroquinolone were enrolled. They received either Bdq+OBR or Mfx(h)+OBR and were followed up for six months. The sputum culture conversion rate at the end of six months and the time to culture conversion in each group were studied. The safety profile of both regimens was also studied. The sputum culture conversion was achieved in 41 patients (100%) in the Bdq+OBR group and 36 patients (87.8%) in the Mfx(h)+OBR group at the end of 6 months. The mean time to culture conversion was found to be 3.10±0.8 months in the Bdq+OBR group and 3.32±0.9 months in the Mfx(h)+OBR group. Mortality was 6.8% in the Bdq+OBR group and 10.8 % in the Mfx(h)+OBR group at 6 months. Raised serum lipase and dark discolouration of skin were significantly more common in the Bdq+OBR group while vomiting and ototoxicity were more common in the Mfx(h)+OBR group. Bdq+OBR was associated with higher success of sputum culture conversion at 6 months and faster sputum culture conversion rate as compared to the Mfx(h)+OBR.
    Language English
    Publishing date 2022-05-04
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 1160940-0
    ISSN 1122-0643 ; 1120-0391
    ISSN 1122-0643 ; 1120-0391
    DOI 10.4081/monaldi.2022.2231
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Gynecomastia in multi-drug resistant tuberculosis - ethionamide the villain.

    Deokar, Kunal / Shaikh, Abdul Latif / Chawla, Gopal

    Advances in respiratory medicine

    2020  Volume 88, Issue 2, Page(s) 162–163

    MeSH term(s) Antitubercular Agents/adverse effects ; Ethionamide/adverse effects ; Gynecomastia/chemically induced ; Gynecomastia/diagnosis ; Humans ; Male ; Middle Aged ; Tuberculosis, Multidrug-Resistant/drug therapy
    Chemical Substances Antitubercular Agents ; Ethionamide (OAY8ORS3CQ)
    Language English
    Publishing date 2020-06-05
    Publishing country Poland
    Document type Case Reports ; Journal Article
    ZDB-ID 2893877-X
    ISSN 2543-6031 ; 2451-4934
    ISSN (online) 2543-6031
    ISSN 2451-4934
    DOI 10.5603/ARM.2020.0093
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: Ocular manifestations of common pulmonary diseases - A narrative review

    Mamta Singh / Kunal Deokar / Bibhuti Prassn Sinha / Monika Keena / Govind Desai

    Monaldi Archives for Chest Disease (2023)

    2023  

    Abstract: Ocular involvement can be a comorbidity of several pulmonary disorders. A knowledge of these manifestations is essential for early diagnosis and treatment. Hence, we aimed to review the common ocular manifestations of Asthma, COPD, sarcoidosis, ... ...

    Abstract Ocular involvement can be a comorbidity of several pulmonary disorders. A knowledge of these manifestations is essential for early diagnosis and treatment. Hence, we aimed to review the common ocular manifestations of Asthma, COPD, sarcoidosis, obstructive sleep apnea and lung cancer. The ocular manifestations of bronchial asthma include allergic keratoconjunctivitis and dry eye. The inhaled corticosteroids used in the management of asthma can lead to cataract formation. COPD is associated with ocular microvascular changes due to chronic hypoxia and spill over of systemic inflammation into the eyes. However, its clinical significance is yet to be known. Ocular involvement is very common in sarcoidosis, seen in 20% of cases of pulmonary sarcoidosis. It can involve almost any anatomical structure of the eye. Studies have shown the association of obstructive sleep apnea (OSA) with floppy eye syndrome, glaucoma, nonarteritic anterior ischemic optic neuropathy, keratoconus, retinal vein occlusion and central serous retinopathy. However, though association has been established, causality remains to be proven. The effect of positive airway pressure (PAP) therapy used in the treatment of OSA on the above ocular conditions is yet to be known. The PAP therapy can itself lead to irritation and dry eyes. Lung cancer can involve the eyes by direct invasion of nerves, ocular metastasis or as a part of paraneoplastic syndrome. The purpose of this narrative review is to raise awareness about the association between ocular and pulmonary disorders to facilitate early detection and treatment of these conditions.
    Keywords ocular sarcoidosis ; floppy eyelid syndrome ; conjunctivitis ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher PAGEPress Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  10. Article ; Online: Comparison of efficacy of bedaquiline and moxifloxacin in drug resistant pulmonary tuberculosis. A prospective observational study

    Govind Desai / Gopal Purohit / Hemant Borana / Kunal Deokar / Suresh Yogi

    Monaldi Archives for Chest Disease (2022)

    2022  

    Abstract: Drug-resistant tuberculosis remains a major public health concern in many countries. We compared the efficacy and safety of bedaquiline plus optimized background regimen (Bdq+OBR) with high dose moxifloxacin and optimized background regimen (Mfx(h)+OBR) ... ...

    Abstract Drug-resistant tuberculosis remains a major public health concern in many countries. We compared the efficacy and safety of bedaquiline plus optimized background regimen (Bdq+OBR) with high dose moxifloxacin and optimized background regimen (Mfx(h)+OBR) for the treatment of patients with multidrug-resistant tuberculosis with additional resistance to fluoroquinolones. In this prospective observational study, newly diagnosed cases of multidrug-resistant tuberculosis with additional resistance to fluoroquinolone were enrolled. They received either Bdq+OBR or Mfx(h)+OBR and were followed up for six months. The sputum culture conversion rate at the end of six months and the time to culture conversion in each group were studied. The safety profile of both regimens was also studied. The sputum culture conversion was achieved in 41 patients (100%) in the Bdq+OBR group and 36 patients (87.8%) in the Mfx(h)+OBR group at the end of 6 months. The mean time to culture conversion was found to be 3.10±0.8 months in the Bdq+OBR group and 3.32±0.9 months in the Mfx(h)+OBR group. Mortality was 6.8% in the Bdq+OBR group and 10.8 % in the Mfx(h)+OBR group at 6 months. Raised serum lipase and dark discolouration of skin were significantly more common in the Bdq+OBR group while vomiting and ototoxicity were more common in the Mfx(h)+OBR group. Bdq+OBR was associated with higher success of sputum culture conversion at 6 months and faster sputum culture conversion rate as compared to the Mfx(h)+OBR.
    Keywords Bedaquiline ; drug-resistant tuberculosis ; sputum culture conversion ; Medicine ; R
    Language English
    Publishing date 2022-05-01T00:00:00Z
    Publisher PAGEPress Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

To top