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  1. Article ; Online: Colorectal disease video channel: free access hub for surgeons, patients and educators.

    Celentano, V / Di Saverio, S

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2020  Volume 22, Issue 3, Page(s) 241–242

    MeSH term(s) Colonic Diseases ; Colorectal Neoplasms/surgery ; Colorectal Surgery ; Humans ; Surgeons
    Language English
    Publishing date 2020-03-18
    Publishing country England
    Document type Editorial
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.15001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Corrigendum to: Inequalities in screening policies and perioperative protection for patients with acute appendicitis during the pandemic: a sub-analysis of the ACIE Appy Study.

    Pellino, G / Podda, M / Pata, F / Di Saverio, S / Ielpo, B

    The British journal of surgery

    2022  Volume 109, Issue 5, Page(s) 464

    Language English
    Publishing date 2022-01-11
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2985-3
    ISSN 1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
    ISSN (online) 1365-2168
    ISSN 0263-1202 ; 0007-1323 ; 1355-7688
    DOI 10.1093/bjs/znab449
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Adhesive Small Bowel Obstruction and the six w's: Who, How, Why, When, What, and Where to diagnose and operate?

    Podda, M / Khan, M / Di Saverio, S

    Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society

    2021  Volume 110, Issue 2, Page(s) 159–169

    Abstract: Background and aims: Approximately 75% of patients admitted with small bowel obstruction have intra-abdominal adhesions as their cause (adhesive small bowel obstruction). Up to 70% of adhesive small bowel obstruction cases, in the absence of ... ...

    Abstract Background and aims: Approximately 75% of patients admitted with small bowel obstruction have intra-abdominal adhesions as their cause (adhesive small bowel obstruction). Up to 70% of adhesive small bowel obstruction cases, in the absence of strangulation and bowel ischemia, can be successfully treated with conservative management. However, emerging evidence shows that surgery performed early during the first episode of adhesive small bowel obstruction is highly effective. The objective of this narrative review is to summarize the current evidence on adhesive small bowel obstruction management strategies.
    Materials and methods: A review of the literature published over the last 20 years was performed to assess Who, hoW, Why, When, What, and Where diagnose and operate on patients with adhesive small bowel obstruction.
    Results: Adequate patient selection through physical examination and computed tomography is the key factor of the entire management strategy, as failure to detect patients with strangulated adhesive small bowel obstruction and bowel ischemia is associated with significant morbidity and mortality. The indication for surgical exploration is usually defined as a failure to pass contrast into the ascending colon within 8-24 h. However, operative management with early adhesiolysis, defined as operative intervention on either the calendar day of admission or the calendar day after admission, has recently shown to be associated with an overall long-term survival benefit compared to conservative management. Regarding the surgical technique, laparoscopy should be used only in selected patients with an anticipated single obstructing band, and there should be a low threshold for conversion to an open procedure in cases of high risk of bowel injuries.
    Conclusion: Although most adhesive small bowel obstruction patients without suspicion of bowel strangulation or gangrene are currently managed nonoperatively, the long-term outcomes following this approach need to be analyzed in a more exhaustive way, as surgery performed early during the first episode of adhesive small bowel obstruction has shown to be highly effective, with a lower rate of recurrence.
    MeSH term(s) Adhesives ; Humans ; Intestinal Obstruction/etiology ; Intestinal Obstruction/surgery ; Intestine, Small/diagnostic imaging ; Intestine, Small/surgery ; Laparoscopy ; Tissue Adhesions/complications ; Tissue Adhesions/diagnosis ; Tissue Adhesions/surgery ; Treatment Outcome
    Chemical Substances Adhesives
    Language English
    Publishing date 2021-01-29
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2077691-3
    ISSN 1799-7267 ; 1457-4969
    ISSN (online) 1799-7267
    ISSN 1457-4969
    DOI 10.1177/1457496920982763
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Inequalities in screening policies and perioperative protection for patients with acute appendicitis during the pandemic: Subanalysis of the ACIE Appy study.

    Pellino, G / Podda, M / Pata, F / Di Saverio, S / Ielpo, B

    The British journal of surgery

    2022  Volume 108, Issue 10, Page(s) e332–e335

    MeSH term(s) Appendicitis/surgery ; COVID-19/diagnosis ; COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19 Testing/statistics & numerical data ; Healthcare Disparities/statistics & numerical data ; Humans ; Mass Screening ; Perioperative Care/statistics & numerical data
    Language English
    Publishing date 2022-01-12
    Publishing country England
    Document type Letter
    ZDB-ID 2985-3
    ISSN 1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
    ISSN (online) 1365-2168
    ISSN 0263-1202 ; 0007-1323 ; 1355-7688
    DOI 10.1093/bjs/znab247
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Interval appendicectomy for complicated appendicitis: do not let your guard down!

    Peltrini, R / Podda, M / Di Saverio, S / Bracale, U / Corcione, F

    The British journal of surgery

    2021  Volume 108, Issue 9, Page(s) e288–e289

    MeSH term(s) Appendectomy/methods ; Appendicitis/surgery ; Humans ; Laparoscopy/methods
    Language English
    Publishing date 2021-05-10
    Publishing country England
    Document type Editorial
    ZDB-ID 2985-3
    ISSN 1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
    ISSN (online) 1365-2168
    ISSN 0263-1202 ; 0007-1323 ; 1355-7688
    DOI 10.1093/bjs/znab158
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Laparoscopic splenic flexure resection for early colorectal cancer, transanal specimen extraction and intracorporeal handsewn anastomosis: a video vignette.

    Crafa, F / Vanella, S / Baiamonte, M / Ruotolo, F / Catalano, O / Di Saverio, S

    Techniques in coloproctology

    2021  Volume 26, Issue 3, Page(s) 227–228

    MeSH term(s) Anastomosis, Surgical ; Colectomy ; Colon, Transverse/surgery ; Colorectal Neoplasms/surgery ; Humans ; Laparoscopy
    Language English
    Publishing date 2021-09-21
    Publishing country Italy
    Document type Journal Article ; Video-Audio Media
    ZDB-ID 2083309-X
    ISSN 1128-045X ; 1123-6337
    ISSN (online) 1128-045X
    ISSN 1123-6337
    DOI 10.1007/s10151-021-02526-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Technique for pancreas-sparing total duodenectomy and reconstruction of a neoduodenum using a free interposed jejunal limb with ampullojejunostomy and Roux-en-Y anastomosis.

    Di Saverio, S / Franchi, C / Kremel, D / Lark, M E / Todero, S / Damaskos, D

    The British journal of surgery

    2021  Volume 108, Issue 2, Page(s) e71–e73

    MeSH term(s) Anastomosis, Roux-en-Y/methods ; Duodenal Ulcer/surgery ; Duodenum/surgery ; Humans ; Jejunum/transplantation ; Male ; Middle Aged ; Pancreas/surgery ; Reconstructive Surgical Procedures/methods
    Language English
    Publishing date 2021-03-11
    Publishing country England
    Document type Case Reports ; Letter ; Video-Audio Media
    ZDB-ID 2985-3
    ISSN 1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
    ISSN (online) 1365-2168
    ISSN 0263-1202 ; 0007-1323 ; 1355-7688
    DOI 10.1093/bjs/znaa097
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Author response: Global attitudes in the management of acute appendicitis during COVID-19 pandemic: ACIE Appy Study.

    Ielpo, B / Podda, M / Pellino, G / Pata, F / Di Saverio, S

    The British journal of surgery

    2021  Volume 108, Issue 9, Page(s) e313

    MeSH term(s) Appendectomy ; Appendicitis/epidemiology ; Appendicitis/surgery ; Attitude ; COVID-19 ; Humans ; Pandemics ; SARS-CoV-2
    Language English
    Publishing date 2021-05-17
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2985-3
    ISSN 1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
    ISSN (online) 1365-2168
    ISSN 0263-1202 ; 0007-1323 ; 1355-7688
    DOI 10.1093/bjs/znab182
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Absence of blood donors' anti-SARS-CoV-2 antibodies in pre-storage leukoreduced red blood cell units indicates no role of passive immunity for blood recipients.

    Casale, Maddalena / Di Girolamo, Maria Grazia / Di Maio, Nicoletta / Tomeo, Rita / Iengo, Martina / Scianguetta, Saverio / Palma, Teresa / Porcelli, Federica / Misso, Saverio / Perrotta, Silverio

    Annals of hematology

    2023  Volume 103, Issue 2, Page(s) 623–629

    Abstract: ... 2 IgG level in donors' serum samples and in RBC units was 8.80 S/C (range 0.01-23.4) and 0.11 (range ... 0.01-0.37) S/C, respectively (p<0.05). This study shows deplasmation and leukodepletion of RBC units ...

    Abstract Transfer of vaccine antibodies (Ab) from donors to recipients after transfusion of packed red blood cells (RBC) is supposed, thus affecting the recipients' response to vaccinations. In this prospective study, SARS-CoV-2 IgG level in donors' serum and RBC supernatant samples was assessed. Among 346 subjects, 280 were referred for hyperimmune plasma donation and 30 for whole blood donations. All units underwent pre-storage filtration, and residual plasma volume was 18±18 mL. The mean total IgG and IgM levels were 171.43 ± 48.79 and 11.43 ± 10.69 mg/dL respectively, with significant reduction after plasma depletion and filtration (IgG 5.86 ± 5.2 and IgM 1.43 ± 3.78, p < 0.05). Anti-COVID-19 Ab were identified in serum of 28/30 (93.5%) blood donors but were absent in all blood units. The mean value of anti-SARS-CoV-2 IgG level in donors' serum samples and in RBC units was 8.80 S/C (range 0.01-23.4) and 0.11 (range 0.01-0.37) S/C, respectively (p<0.05). This study shows deplasmation and leukodepletion of RBC units ensured removal of IgG content and no red blood cell unit was reactive for anti-COVID-19 antibodies even from donors with high serum titre. These findings demonstrate that deplasmated and leukodepleted RBCs are not to be considered blood products containing substantial amounts of immune globulin, and differently from other blood derived-products containing Ab, transfusions with deplasmated and leukodepleted RBCs do not require delayed vaccinations and a revision of current recommendations is requested.
    MeSH term(s) Humans ; COVID-19 ; Blood Donors ; SARS-CoV-2 ; Prospective Studies ; Erythrocytes ; Immunoglobulin G ; Immunoglobulin M ; Antibodies, Viral
    Chemical Substances Immunoglobulin G ; Immunoglobulin M ; Antibodies, Viral
    Language English
    Publishing date 2023-09-27
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1064950-5
    ISSN 1432-0584 ; 0939-5555 ; 0945-8077
    ISSN (online) 1432-0584
    ISSN 0939-5555 ; 0945-8077
    DOI 10.1007/s00277-023-05473-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Acute appendicitis during the COVID-19 lockdown: never waste a crisis!

    Podda, M / Pata, F / Pellino, G / Ielpo, B / Di Saverio, S

    The British journal of surgery

    2021  Volume 108, Issue 1, Page(s) e31–e32

    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Appendectomy/statistics & numerical data ; Appendicitis/diagnosis ; Appendicitis/epidemiology ; Appendicitis/therapy ; COVID-19/prevention & control ; Emergency Service, Hospital/statistics & numerical data ; Facilities and Services Utilization ; Humans ; Laparoscopy/statistics & numerical data ; Pandemics/prevention & control ; Quarantine ; SARS-CoV-2
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2021-02-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 2985-3
    ISSN 1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
    ISSN (online) 1365-2168
    ISSN 0263-1202 ; 0007-1323 ; 1355-7688
    DOI 10.1093/bjs/znaa073
    Database MEDical Literature Analysis and Retrieval System OnLINE

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