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Article ; Online: A redescending M-estimator approach for outlier-resilient modeling.

Raza, Aamir / Noor-Ul-Amin, Muhammad / Ayari-Akkari, Amel / Nabi, Muhammad / Usman Aslam, Muhammad

2024 Volume 14, Issue 1, Page(s) 7131

Abstract: ... M-estimators (MEs) come into play to obtain reliable estimates. We introduce a redescending M ...

Abstract	The OLS model is built on the assumption of normality in the distribution of error terms. However, this assumption can be easily violated, especially when there are outliers in the data. A single outlier can disrupt the normality assumption of error terms, making the OLS model less effective. In such situations, M-estimators (MEs) come into play to obtain reliable estimates. We introduce a redescending M-estimators (RME) for robust regression to handle datasets with outliers. The proposed RME produces more robust estimates by effectively managing the influence of outliers, even at lower values of the tuning constant. We compared the performance of this estimator with existing RMEs using real-life data examples and an extensive simulation study. The results show that our suggested RME is more efficient than the compared ME in various situations.
Language	English
Publishing date	2024-03-26
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-57906-1
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: M. tuberculosis

Stephanie, Filia / Tambunan, Usman Sumo Friend / Siahaan, Teruna J

Life (Basel, Switzerland)

2022 Volume 12, Issue 11

Abstract: Mycobacterium ... ...

Abstract	Mycobacterium tuberculosis
Language	English
Publishing date	2022-11-03
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2662250-6
ISSN	2075-1729
ISSN	2075-1729
DOI	10.3390/life12111774
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Article ; Online: M. tuberculosis Transcription Machinery

Filia Stephanie / Usman Sumo Friend Tambunan / Teruna J. Siahaan

Life, Vol 12, Iss 1774, p

A Review on the Mycobacterial RNA Polymerase and Drug Discovery Efforts

2022 Volume 1774

Abstract: Mycobacterium tuberculosis (MTB) is the main source of tuberculosis (TB), one of the oldest known diseases in the human population. Despite the drug discovery efforts of past decades, TB is still one of the leading causes of mortality and claimed more ... ...

Abstract	Mycobacterium tuberculosis (MTB) is the main source of tuberculosis (TB), one of the oldest known diseases in the human population. Despite the drug discovery efforts of past decades, TB is still one of the leading causes of mortality and claimed more than 1.5 million lives worldwide in 2020. Due to the emergence of drug-resistant strains and patient non-compliance during treatments, there is a pressing need to find alternative therapeutic agents for TB. One of the important areas for developing new treatments is in the inhibition of the transcription step of gene expression; it is the first step to synthesize a copy of the genetic material in the form of mRNA. This further translates to functional protein synthesis, which is crucial for the bacteria living processes. MTB contains a bacterial DNA-dependent RNA polymerase (RNAP), which is the key enzyme for the transcription process. MTB RNAP has been targeted for designing and developing antitubercular agents because gene transcription is essential for the mycobacteria survival. Initiation, elongation, and termination are the three important sequential steps in the transcription process. Each step is complex and highly regulated, involving multiple transcription factors. This review is focused on the MTB transcription machinery, especially in the nature of MTB RNAP as the main enzyme that is regulated by transcription factors. The mechanism and conformational dynamics that occur during transcription are discussed and summarized. Finally, the current progress on MTB transcription inhibition and possible drug target in mycobacterial RNAP are also described to provide insight for future antitubercular drug design and development.
Keywords	M. tuberculosis ; DNA-dependent RNA polymerase ; transcription inhibition ; Science ; Q
Subject code	572
Language	English
Publishing date	2022-11-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
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Article ; Online: Comparative Study of Molecular Descriptors of Pent-Heptagonal Nanostructures Using Neighborhood M-Polynomial Approach.

Xavier, D Antony / Ghani, Muhammad Usman / Imran, Muhammad / Nair A, Theertha / Varghese, Eddith Sarah / Baby, Annmaria

Molecules (Basel, Switzerland)

2023 Volume 28, Issue 6

Abstract: ... mathematical chemistry has a lot to offer. One such approach is the M-polynomial, a fundamental polynomial ... that can generate a significant number of degree-based topological indices. Among them, the neighborhood M ... in carrying out physical, chemical, and biological experiments. This paper formulates the unique M-polynomial ...

Abstract	In this article, a novel technique to evaluate and compare the neighborhood degree molecular descriptors of two variations of the carbon nanosheet C5C7(a,b) is presented. The conjugated molecules follow the graph spectral theory, in terms of bonding, non-bonding and antibonding Ruckel molecular orbitals. They are demonstrated to be immediately determinable from their topological characteristics. The effort of chemical and pharmaceutical researchers is significantly increased by the need to conduct numerous chemical experiments to ascertain the chemical characteristics of such a wide variety of novel chemicals. In order to generate novel cellular imaging techniques and to accomplish the regulation of certain cellular mechanisms, scientists have utilized the attributes of nanosheets such as their flexibility and simplicity of modification, out of which carbon nanosheets stand out for their remarkable strength, chemical stability, and electrical conductivity. With efficient tools like polynomials and functions that can forecast compound features, mathematical chemistry has a lot to offer. One such approach is the M-polynomial, a fundamental polynomial that can generate a significant number of degree-based topological indices. Among them, the neighborhood M-polynomial is useful in retrieving neighborhood degree sum-based topological indices that can help in carrying out physical, chemical, and biological experiments. This paper formulates the unique M-polynomial approach which is used to derive and compare a variety of neighborhood degree-based molecular descriptors and the corresponding entropy measures of two variations of pent-heptagonal carbon nanosheets. Furthermore, a regression analysis on these descriptors has also been carried out which can further help in the prediction of various properties of the molecule.
Language	English
Publishing date	2023-03-09
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	1413402-0
ISSN	1420-3049 ; 1431-5165 ; 1420-3049
ISSN (online)	1420-3049
ISSN	1431-5165 ; 1420-3049
DOI	10.3390/molecules28062518
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Article ; Online: A novel perspective for M-polynomials to compute molecular descriptors of borophene nanosheet.

Ismail, Rashad / Baby, Annmaria / Xavier, D Antony / Varghese, Eddith Sarah / Ghani, Muhammad Usman / Nair, A Theertha / Karamti, Hanen

Scientific reports

2023 Volume 13, Issue 1, Page(s) 12016

Abstract: ... was a major advance in the fields of mathematics and chemistry, with a wide range of applications. M ... are established in this study utilising the M-polynomial technique. A program code that enables ... to generate the M-polynomial of any chemical structure was developed in Java platform and the same is ...

Abstract	Nanomaterials feature exceptional, one-of-a-kind qualities that might be used in electronics, medicine, and other industries. Two-dimensional nanomaterials called borophene have a variety of intriguing characteristics, which helped them to leave an indelible impression in the fields of chemistry, material science, nanotechnology, and condensed matter physics. The concept of modelling the structure of a molecule or chemical network to a chemical graph and then quantitatively analysing them with the aid of topological descriptors was a major advance in the fields of mathematics and chemistry, with a wide range of applications. M-polynomial approach is a very versatile and quick method for computing the degree-based descriptors of chemical graphs or networks. The degree-based descriptors of the [Formula: see text]-Borophene nanosheet are established in this study utilising the M-polynomial technique. A program code that enables to generate the M-polynomial of any chemical structure was developed in Java platform and the same is displayed. At the conclusion, the numerical and graphical comparison based on the identified analytic expressions is also provided. Additionally, the QSPR analysis was also carried out and the outcoms are presented therein.
Language	English
Publishing date	2023-07-25
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-37637-5
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Article ; Online: GW190521: A Binary Black Hole Merger with a Total Mass of 150 M_{⊙}.

Abbott, R / Abbott, T D / Abraham, S / Acernese, F / Ackley, K / Adams, C / Adhikari, R X / Adya, V B / Affeldt, C / Agathos, M / Agatsuma, K / Aggarwal, N / Aguiar, O D / Aich, A / Aiello, L / Ain, A / Ajith, P / Akcay, S / Allen, G /

Allocca, A / Altin, P A / Amato, A / Anand, S / Ananyeva, A / Anderson, S B / Anderson, W G / Angelova, S V / Ansoldi, S / Antier, S / Appert, S / Arai, K / Araya, M C / Areeda, J S / Arène, M / Arnaud, N / Aronson, S M / Arun, K G / Asali, Y / Ascenzi, S / Ashton, G / Aston, S M / Astone, P / Aubin, F / Aufmuth, P / AultONeal, K / Austin, C / Avendano, V / Babak, S / Bacon, P / Badaracco, F / Bader, M K M / Bae, S / Baer, A M / Baird, J / Baldaccini, F / Ballardin, G / Ballmer, S W / Bals, A / Balsamo, A / Baltus, G / Banagiri, S / Bankar, D / Bankar, R S / Barayoga, J C / Barbieri, C / Barish, B C / Barker, D / Barkett, K / Barneo, P / Barone, F / Barr, B / Barsotti, L / Barsuglia, M / Barta, D / Bartlett, J / Bartos, I / Bassiri, R / Basti, A / Bawaj, M / Bayley, J C / Bazzan, M / Bécsy, B / Bejger, M / Belahcene, I / Bell, A S / Beniwal, D / Benjamin, M G / Bentley, J D / Bergamin, F / Berger, B K / Bergmann, G / Bernuzzi, S / Berry, C P L / Bersanetti, D / Bertolini, A / Betzwieser, J / Bhandare, R / Bhandari, A V / Bidler, J / Biggs, E / Bilenko, I A / Billingsley, G / Birney, R / Birnholtz, O / Biscans, S / Bischi, M / Biscoveanu, S / Bisht, A / Bissenbayeva, G / Bitossi, M / Bizouard, M A / Blackburn, J K / Blackman, J / Blair, C D / Blair, D G / Blair, R M / Bobba, F / Bode, N / Boer, M / Boetzel, Y / Bogaert, G / Bondu, F / Bonilla, E / Bonnand, R / Booker, P / Boom, B A / Bork, R / Boschi, V / Bose, S / Bossilkov, V / Bosveld, J / Bouffanais, Y / Bozzi, A / Bradaschia, C / Brady, P R / Bramley, A / Branchesi, M / Brau, J E / Breschi, M / Briant, T / Briggs, J H / Brighenti, F / Brillet, A / Brinkmann, M / Brockill, P / Brooks, A F / Brooks, J / Brown, D D / Brunett, S / Bruno, G / Bruntz, R / Buikema, A / Bulik, T / Bulten, H J / Buonanno, A / Buscicchio, R / Buskulic, D / Byer, R L / Cabero, M / Cadonati, L / Cagnoli, G / Cahillane, C / Calderón Bustillo, J / Callaghan, J D / Callister, T A / Calloni, E / Camp, J B / Canepa, M / Cannon, K C / Cao, H / Cao, J / Carapella, G / Carbognani, F / Caride, S / Carney, M F / Carullo, G / Casanueva Diaz, J / Casentini, C / Castañeda, J / Caudill, S / Cavaglià, M / Cavalier, F / Cavalieri, R / Cella, G / Cerdá-Durán, P / Cesarini, E / Chaibi, O / Chakravarti, K / Chan, C / Chan, M / Chandra, K / Chao, S / Charlton, P / Chase, E A / Chassande-Mottin, E / Chatterjee, D / Chaturvedi, M / Chatziioannou, K / Chen, H Y / Chen, X / Chen, Y / Cheng, H-P / Cheong, C K / Chia, H Y / Chiadini, F / Chierici, R / Chincarini, A / Chiummo, A / Cho, G / Cho, H S / Cho, M / Christensen, N / Chu, Q / Chua, S / Chung, K W / Chung, S / Ciani, G / Ciecielag, P / Cieślar, M / Ciobanu, A A / Ciolfi, R / Cipriano, F / Cirone, A / Clara, F / Clark, J A / Clearwater, P / Clesse, S / Cleva, F / Coccia, E / Cohadon, P-F / Cohen, D / Colleoni, M / Collette, C G / Collins, C / Colpi, M / Constancio, M / Conti, L / Cooper, S J / Corban, P / Corbitt, T R / Cordero-Carrión, I / Corezzi, S / Corley, K R / Cornish, N / Corre, D / Corsi, A / Cortese, S / Costa, C A / Cotesta, R / Coughlin, M W / Coughlin, S B / Coulon, J-P / Countryman, S T / Couvares, P / Covas, P B / Coward, D M / Cowart, M J / Coyne, D C / Coyne, R / Creighton, J D E / Creighton, T D / Cripe, J / Croquette, M / Crowder, S G / Cudell, J-R / Cullen, T J / Cumming, A / Cummings, R / Cunningham, L / Cuoco, E / Curylo, M / Canton, T Dal / Dálya, G / Dana, A / Daneshgaran-Bajastani, L M / D'Angelo, B / Danilishin, S L / D'Antonio, S / Danzmann, K / Darsow-Fromm, C / Dasgupta, A / Datrier, L E H / Dattilo, V / Dave, I / Davier, M / Davies, G S / Davis, D / Daw, E J / DeBra, D / Deenadayalan, M / Degallaix, J / De Laurentis, M / Deléglise, S / Delfavero, M / De Lillo, N / Del Pozzo, W / DeMarchi, L M / D'Emilio, V / Demos, N / Dent, T / De Pietri, R / De Rosa, R / De Rossi, C / DeSalvo, R / de Varona, O / Dhurandhar, S / Díaz, M C / Diaz-Ortiz, M / Dietrich, T / Di Fiore, L / Di Fronzo, C / Di Giorgio, C / Di Giovanni, F / Di Giovanni, M / Di Girolamo, T / Di Lieto, A / Ding, B / Di Pace, S / Di Palma, I / Di Renzo, F / Divakarla, A K / Dmitriev, A / Doctor, Z / Donovan, F / Dooley, K L / Doravari, S / Dorrington, I / Downes, T P / Drago, M / Driggers, J C / Du, Z / Ducoin, J-G / Dupej, P / Durante, O / D'Urso, D / Dwyer, S E / Easter, P J / Eddolls, G / Edelman, B / Edo, T B / Edy, O / Effler, A / Ehrens, P / Eichholz, J / Eikenberry, S S / Eisenmann, M / Eisenstein, R A / Ejlli, A / Errico, L / Essick, R C / Estelles, H / Estevez, D / Etienne, Z B / Etzel, T / Evans, M / Evans, T M / Ewing, B E / Fafone, V / Fairhurst, S / Fan, X / Farinon, S / Farr, B / Farr, W M / Fauchon-Jones, E J / Favata, M / Fays, M / Fazio, M / Feicht, J / Fejer, M M / Feng, F / Fenyvesi, E / Ferguson, D L / Fernandez-Galiana, A / Ferrante, I / Ferreira, E C / Ferreira, T A / Fidecaro, F / Fiori, I / Fiorucci, D / Fishbach, M / Fisher, R P / Fittipaldi, R / Fitz-Axen, M / Fiumara, V / Flaminio, R / Floden, E / Flynn, E / Fong, H / Font, J A / 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A L / Jani, K / Janthalur, N N / Jaranowski, P / Jariwala, D / Jaume, R / Jenkins, A C / Jiang, J / Johns, G R / Johnson-McDaniel, N K / Jones, A W / Jones, D I / Jones, J D / Jones, P / Jones, R / Jonker, R J G / Ju, L / Junker, J / Kalaghatgi, C V / Kalogera, V / Kamai, B / Kandhasamy, S / Kang, G / Kanner, J B / Kapadia, S J / Karki, S / Kashyap, R / Kasprzack, M / Kastaun, W / Katsanevas, S / Katsavounidis, E / Katzman, W / Kaufer, S / Kawabe, K / Kéfélian, F / Keitel, D / Keivani, A / Kennedy, R / Key, J S / Khadka, S / Khalili, F Y / Khan, I / Khan, S / Khan, Z A / Khazanov, E A / Khetan, N / Khursheed, M / Kijbunchoo, N / Kim, Chunglee / Kim, G J / Kim, J C / Kim, K / Kim, W / Kim, W S / Kim, Y-M / Kimball, C / King, P J / Kinley-Hanlon, M / Kirchhoff, R / Kissel, J S / Kleybolte, L / Klimenko, S / Knowles, T D / Knyazev, E / Koch, P / Koehlenbeck, S M / Koekoek, G / Koley, S / Kondrashov, V / Kontos, A / Koper, N / Korobko, M / Korth, W Z / Kovalam, M / Kozak, D B / Kringel, V / Krishnendu, N V / Królak, A / Krupinski, N / Kuehn, G / Kumar, A / Kumar, P / Kumar, Rahul / Kumar, Rakesh / Kumar, S / Kuo, L / Kutynia, A / Lackey, B D / Laghi, D / Lalande, E / Lam, T L / Lamberts, A / Landry, M / Lane, B B / Lang, R N / Lange, J / Lantz, B / Lanza, R K / La Rosa, I / Lartaux-Vollard, A / Lasky, P D / Laxen, M / Lazzarini, A / Lazzaro, C / Leaci, P / Leavey, S / Lecoeuche, Y K / Lee, C H / Lee, H M / Lee, H W / Lee, J / Lee, K / Lehmann, J / Leroy, N / Letendre, N / Levin, Y / Li, A K Y / Li, J / Li, K / Li, T G F / Li, X / Linde, F / Linker, S D / Linley, J N / Littenberg, T B / Liu, J / Liu, X / Llorens-Monteagudo, M / Lo, R K L / Lockwood, A / London, L T / Longo, A / Lorenzini, M / Loriette, V / Lormand, M / Losurdo, G / Lough, J D / Lousto, C O / Lovelace, G / Lück, H / Lumaca, D / Lundgren, A P / Ma, Y / Macas, R / Macfoy, S / MacInnis, M / Macleod, D M / MacMillan, I A O / Macquet, A / Magaña Hernandez, I / Magaña-Sandoval, F / Magee, R M / Majorana, E / Maksimovic, I / Malik, A / Man, N / Mandic, V / Mangano, V / Mansell, G L / Manske, M / Mantovani, M / Mapelli, M / Marchesoni, F / Marion, F / Márka, S / Márka, Z / Markakis, C / Markosyan, A S / Markowitz, A / Maros, E / Marquina, A / Marsat, S / Martelli, F / Martin, I W / Martin, R M / Martinez, V / Martynov, D V / Masalehdan, H / Mason, K / Massera, E / Masserot, A / Massinger, T J / Masso-Reid, M / Mastrogiovanni, S / Matas, A / Matichard, F / Mavalvala, N / Maynard, E / McCann, J J / McCarthy, R / McClelland, D E / McCormick, S / McCuller, L / McGuire, S C / McIsaac, C / McIver, J / McManus, D J / McRae, T / McWilliams, S T / Meacher, D / Meadors, G D / Mehmet, M / Mehta, A K / Mejuto Villa, E / Melatos, A / Mendell, G / Mercer, R A / Mereni, L / Merfeld, K / Merilh, E L / Merritt, J D / Merzougui, M / Meshkov, S / Messenger, C / Messick, C / Metzdorff, R / Meyers, P M / Meylahn, F / Mhaske, A / Miani, A / Miao, H / Michaloliakos, I / Michel, C / Middleton, H / Milano, L / Miller, A L / Millhouse, M / Mills, J C / Milotti, E / Milovich-Goff, M C / Minazzoli, O / Minenkov, Y / Mishkin, A / Mishra, C / Mistry, T / Mitra, S / Mitrofanov, V P / Mitselmakher, G / Mittleman, R / Mo, G / Mogushi, K / Mohapatra, S R P / Mohite, S R / Molina-Ruiz, M / Mondin, M / Montani, M / Moore, C J / Moraru, D / Morawski, F / Moreno, G / Morisaki, S / Mours, B / Mow-Lowry, C M / Mozzon, S / Muciaccia, F / Mukherjee, Arunava / Mukherjee, D / Mukherjee, S / Mukherjee, Subroto / Mukund, N / Mullavey, A / Munch, J / Muñiz, E A / Murray, P G / Nagar, A / Nardecchia, I / Naticchioni, L / Nayak, R K / Neil, B F / Neilson, J / Nelemans, G / Nelson, T J N / Nery, M / Neunzert, A / Ng, K Y / Ng, S / Nguyen, C / Nguyen, P / Nichols, D / Nichols, S A / Nissanke, S / Nitz, A / Nocera, F / Noh, M / North, C / Nothard, D / Nuttall, L K / Oberling, J / O'Brien, B D / Oganesyan, G / Ogin, G H / Oh, J J / Oh, S H / Ohme, F / Ohta, H / Okada, M A / Oliver, M / Olivetto, C / Oppermann, P / Oram, Richard J / O'Reilly, B / Ormiston, R G / Ortega, L F / O'Shaughnessy, R / Ossokine, S / Osthelder, C / Ottaway, D J / Overmier, H / Owen, B J / Pace, A E / Pagano, G / Page, M A / Pagliaroli, G / Pai, A / Pai, S A / Palamos, J R / Palashov, O / Palomba, C / Pan, H / Panda, P K / Pang, P T H / Pankow, C / Pannarale, F / Pant, B C / Paoletti, F / Paoli, A / Parida, A / Parker, W / Pascucci, D / Pasqualetti, A / Passaquieti, R / Passuello, D / Patricelli, B / Payne, E / Pearlstone, B L / Pechsiri, T C / Pedersen, A J / Pedraza, M / Pele, A / Penn, S / Perego, A / Perez, C J / Périgois, C / Perreca, A / Perriès, S / Petermann, J / Pfeiffer, H P / Phelps, M / Phukon, K S / Piccinni, O J / Pichot, M / Piendibene, M / Piergiovanni, F / Pierro, V / Pillant, G / Pinard, L / Pinto, I M / Piotrzkowski, K / Pirello, M / Pitkin, M / Plastino, W / Poggiani, R / Pong, D Y T / Ponrathnam, S / Popolizio, P / Porter, E K / Powell, J / Prajapati, A K / Prasai, K / Prasanna, R / Pratten, G / Prestegard, T / Principe, M / Prodi, G A / Prokhorov, L / Punturo, M / Puppo, P / Pürrer, M / Qi, H / Quetschke, V / Quinonez, P J / Raab, F J / Raaijmakers, G / Radkins, H / Radulesco, N / Raffai, P / Rafferty, H / Raja, S / Rajan, C / Rajbhandari, B / Rakhmanov, M / Ramirez, K E / Ramos-Buades, A / Rana, Javed / Rao, K / Rapagnani, P / Raymond, V / Razzano, M / Read, J / Regimbau, T / Rei, L / Reid, S / Reitze, D H / Rettegno, P / Ricci, F / Richardson, C J / Richardson, J W / Ricker, P M / Riemenschneider, G / Riles, K / Rizzo, M / Robertson, N A / Robinet, F / Rocchi, A / Rodriguez-Soto, R D / Rolland, L / Rollins, J G / Roma, V J / Romanelli, M / Romano, R / Romel, C L / Romero-Shaw, I M / Romie, J H / Rose, C A / Rose, D / Rose, K / Rosińska, D / Rosofsky, S G / Ross, M P / Rowan, S / Rowlinson, S J / Roy, P K / Roy, Santosh / Roy, Soumen / Ruggi, P / Rutins, G / Ryan, K / Sachdev, S / Sadecki, T / Sakellariadou, M / Salafia, O S / Salconi, L / Saleem, M / Salemi, F / Samajdar, A / Sanchez, E J / Sanchez, L E / Sanchis-Gual, N / Sanders, J R / Santiago, K A / Santos, E / Sarin, N / Sassolas, B / Sathyaprakash, B S / Sauter, O / Savage, R L / Savant, V / Sawant, D / Sayah, S / Schaetzl, D / Schale, P / Scheel, M / Scheuer, J / Schmidt, P / Schnabel, R / Schofield, R M S / Schönbeck, A / Schreiber, E / Schulte, B W / Schutz, B F / Schwarm, O / Schwartz, E / Scott, J / Scott, S M / Seidel, E / Sellers, D / Sengupta, A S / Sennett, N / Sentenac, D / Sequino, V / Sergeev, A / Setyawati, Y / Shaddock, D A / Shaffer, T / Sharifi, S / Shahriar, M S / Sharma, A / Sharma, P / Shawhan, P / Shen, H / Shikauchi, M / Shink, R / Shoemaker, D H / Shoemaker, D M / Shukla, K / ShyamSundar, S / Siellez, K / Sieniawska, M / Sigg, D / Singer, L P / Singh, D / Singh, N / Singha, A / Singhal, A / Sintes, A M / Sipala, V / Skliris, V / Slagmolen, B J J / Slaven-Blair, T J / Smetana, J / Smith, J R / Smith, R J E / Somala, S / Son, E J / Soni, S / Sorazu, B / Sordini, V / Sorrentino, F / Souradeep, T / Sowell, E / Spencer, A P / Spera, M / Srivastava, A K / Srivastava, V / Staats, K / Stachie, C / Standke, M / Steer, D A / Steinke, M / Steinlechner, J / Steinlechner, S / Steinmeyer, D / Stevenson, S / Stocks, D / Stops, D J / Stover, M / Strain, K A / Stratta, G / Strunk, A / Sturani, R / Stuver, A L / Sudhagar, S / Sudhir, V / Summerscales, T Z / Sun, L / Sunil, S / Sur, A / Suresh, J / Sutton, P J / Swinkels, B L / Szczepańczyk, M J / Tacca, M / Tait, S C / Talbot, C / Tanasijczuk, A J / Tanner, D B / Tao, D / Tápai, M / Tapia, A / Tapia San Martin, E N / Tasson, J D / Taylor, R / Tenorio, R / Terkowski, L / Thirugnanasambandam, M P / Thomas, M / Thomas, P / Thompson, J E / Thondapu, S R / Thorne, K A / Thrane, E / Tinsman, C L / Saravanan, T R / Tiwari, Shubhanshu / Tiwari, S / Tiwari, V / Toland, K / Tonelli, M / Tornasi, Z / Torres-Forné, A / Torrie, C I / Tosta E Melo, I / Töyrä, D / Travasso, F / Traylor, G / Tringali, M C / Tripathee, A / Trovato, A / 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Wellmann, F / Wen, L / Weßels, P / Westhouse, J W / Wette, K / Whelan, J T / Whiting, B F / Whittle, C / Wilken, D M / Williams, D / Willis, J L / Willke, B / Winkler, W / Wipf, C C / Wittel, H / Woan, G / Woehler, J / Wofford, J K / Wong, I C F / Wright, J L / Wu, D S / Wysocki, D M / Xiao, L / Yamamoto, H / Yang, L / Yang, Y / Yang, Z / Yap, M J / Yazback, M / Yeeles, D W / Yu, Hang / Yu, Haocun / Yuen, S H R / Zadrożny, A K / Zadrożny, A / Zanolin, M / Zelenova, T / Zendri, J-P / Zevin, M / Zhang, J / Zhang, L / Zhang, T / Zhao, C / Zhao, G / Zhou, M / Zhou, Z / Zhu, X J / Zimmerman, A B / Zucker, M E / Zweizig, J

Physical review letters

2021 Volume 125, Issue 10, Page(s) 101102

Abstract: ... with masses of 85_{-14}^{+21} M_{⊙} and 66_{-18}^{+17} M_{⊙} (90% credible intervals). We infer ... with only a 0.32% probability of being below 65 M_{⊙}. We calculate the mass of the remnant to be 142_{-16 ... 28} M_{⊙}, which can be considered an intermediate mass black hole (IMBH). The luminosity distance ...

Abstract	On May 21, 2019 at 03:02:29 UTC Advanced LIGO and Advanced Virgo observed a short duration gravitational-wave signal, GW190521, with a three-detector network signal-to-noise ratio of 14.7, and an estimated false-alarm rate of 1 in 4900 yr using a search sensitive to generic transients. If GW190521 is from a quasicircular binary inspiral, then the detected signal is consistent with the merger of two black holes with masses of 85_{-14}^{+21} M_{⊙} and 66_{-18}^{+17} M_{⊙} (90% credible intervals). We infer that the primary black hole mass lies within the gap produced by (pulsational) pair-instability supernova processes, with only a 0.32% probability of being below 65 M_{⊙}. We calculate the mass of the remnant to be 142_{-16}^{+28} M_{⊙}, which can be considered an intermediate mass black hole (IMBH). The luminosity distance of the source is 5.3_{-2.6}^{+2.4} Gpc, corresponding to a redshift of 0.82_{-0.34}^{+0.28}. The inferred rate of mergers similar to GW190521 is 0.13_{-0.11}^{+0.30} Gpc^{-3} yr^{-1}.
Language	English
Publishing date	2021-02-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.125.101102
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Article ; Online: Unlocking the potential of novel RTS, S/AS01, and R21/Matrix-M™ malaria vaccines in African nations.

Oduoye, Malik Olatunde / Haider, Muhammad Usman / Marsool, Mohammed Dheyaa Marsool / Kareem, Mayowa Odunayo / Adedayo, Adenike Ebunoluwa / Abdulkarim, Abdulkarim Surajo / Adegoke, Abdullahi Adeyemi / Kaushik, Ikshwaki / Irfan, Hamza / Yusuf, Hassan Abdullahi / Shah, Hussain Haider / Karim, Karim Arif

Health science reports

2024 Volume 7, Issue 1, Page(s) e1797

Abstract: ... Strategies," and "Public Health.": Results: The recently approved RTS, S/AS01, and R21/Matrix-M™ ...

Abstract	Introduction: Mass malaria vaccination, rather than vaccinating only children below age 5, has been proven to have the potential to reduce morbidity and mortality among those vaccinated, both young and old. Addressing vaccine scepticism and misinformation is crucial in African nations to build public trust in malaria prevention. Therefore, including a wider range of demographics in vaccine trials is necessary for equitable representation and achieving herd immunity against malaria. Aim: This present article aims to identify some of the obstacles that impede malaria vaccination usage and acceptability in African Nations in combating malaria in the region as it continues to pose a significant global public health problem. Methodology: A literature search was done on the Malaria vaccine between 2000 and 2023. Past and present articles/studies on this topic were consulted on PubMed, Google Scholar, Scopus and Web of Science using the following keywords; "Malaria," "Vaccines," "African Nations," "Obstacles, Strategies," and "Public Health." Results: The recently approved RTS, S/AS01, and R21/Matrix-M™ Malaria vaccines have the potential to prevent numerous deaths and cases of Malaria in Africa. These vaccines Malaria vaccines are cost-effective in African areas with moderate to high plasmodium falciparum and can be delivered through routine immunization. Conclusion: To combat malaria effectively in African Nations, African leaders need to set up a comprehensive approach that involves; prevention, healthcare access, implementation research strategies towards adoption and acceptance of malaria vaccines in Africa as well as community engagement with the religious leaders, the market women, community heads, schools, as well as students' union towards the willingness and acceptability of the malaria vaccines among the African populations.
Language	English
Publishing date	2024-01-04
Publishing country	United States
Document type	Journal Article
ISSN	2398-8835
ISSN (online)	2398-8835
DOI	10.1002/hsr2.1797
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Article ; Online: Nickel -supported PdM (M = Au and Ag) nanodendrites as formate oxidation (electro)catalytic anodes for direct fuel cells and hydrogen generation at room temperature.

Pan, Bowei / Shan, Shuang / Wang, Junpeng / Tang, Quan / Guo, Longfei / Jin, Tao / Wang, Qiao / Li, Zhen / Usman, Muhammad / Chen, Fuyi

Nanoscale

2023 Volume 15, Issue 15, Page(s) 7032–7043

Abstract: The study provides a proof of concept for the first time that unique palladium-gold (PdAu) and palladium-silver (PdAg) nanodendrites are bifunctional catalytic active sites for formate oxidation reactions (FORs) and formate dehydrogenation reactions ( ... ...

Abstract	The study provides a proof of concept for the first time that unique palladium-gold (PdAu) and palladium-silver (PdAg) nanodendrites are bifunctional catalytic active sites for formate oxidation reactions (FORs) and formate dehydrogenation reactions (FDRs). The unique nanodendritic structure was developed
Language	English
Publishing date	2023-04-13
Publishing country	England
Document type	Journal Article
ZDB-ID	2515664-0
ISSN	2040-3372 ; 2040-3364
ISSN (online)	2040-3372
ISSN	2040-3364
DOI	10.1039/d2nr06637h
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Article ; Online: Author Correction: A novel perspective for M-polynomials to compute molecular descriptors of borophene nanosheet.

Ismail, Rashad / Baby, Annmaria / Xavier, D Antony / Varghese, Eddith Sarah / Ghani, Muhammad Usman / Nair, A Theertha / Karamti, Hanen

Scientific reports

2023 Volume 13, Issue 1, Page(s) 13035

Language	English
Publishing date	2023-08-10
Publishing country	England
Document type	Published Erratum
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-40229-y
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Article ; Online: The International Association for the Study of Lung Cancer Thymic Epithelial Tumors Staging Project: Proposals for the N and the M Components for the Forthcoming (Ninth) Edition of the TNM Classification of Malignant Tumors.

Fang, Wentao / Girard, Nicolas / Cilento, Vanessa / Goren, Emily / Dibaba, Daniel / Ruffini, Enrico / Ahmad, Usman / Appel, Sarit / Bille, Andrea / Boubia, Souheil / Brambilla, Cecilia / Cangir, Ayten Kayi / Detterbeck, Frank / Falkson, Conrad / Filosso, Pier Luigi / Giaccone, Giuseppe / Guerrera, Francesco / Huang, James / Infante, Maurizio /

Kim, Dong Kwan / Lucchi, Marco / Marino, Mirella / Marom, Edith M / Nicholson, Andrew G / Okumura, Meinoshin / Rami-Porta, Ramon / Rimner, Andreas / Simone, Charles B / Asamura, Hisao

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

2023 Volume 19, Issue 1, Page(s) 52–70

Abstract: ... with cancer and rests on a combination of three components-T for tumor extent, N for nodal involvement, and M ... for distant metastases. This article details the revision of the N and the M components of thymic epithelial ... The N and M components of the eighth edition staging system were verified by a large international ...

Abstract	Introduction: Stage classification is an important underpinning of management in patients with cancer and rests on a combination of three components-T for tumor extent, N for nodal involvement, and M for distant metastases. This article details the revision of the N and the M components of thymic epithelial tumors for the ninth edition of the TNM classification of malignant tumors proposed by the Thymic Domain of the International Association for the Study of Lung Cancer Staging and Prognostic Factors Committee. Methods: The N and M components of the eighth edition staging system were verified by a large international collaborative data source through a data-driven analysis. A total of 9147 cases were included for analysis, including 7662 thymomas, 1345 thymic carcinomas, and 140 neuroendocrine thymic tumors. Results: Lymph node involvement rates were 1.5% in thymomas and 17.6% and 27.7% in thymic carcinomas and neuroendocrine thymic tumors, respectively. Rates of lymph node metastasis were increasingly higher in tumors with higher T stage and higher-grade histologic type. Survival analysis validated the differences in the N and M categories proposed in the eighth edition staging system. Good discrimination in overall survival was detected among pathologic (p)N and pM categories in patients with thymoma and thymic carcinoma. Conclusions: No changes are proposed from the eighth edition for the N and M components. The proposed stage classification will provide a useful tool for management of the disease among the global thymic community.
MeSH term(s)	Humans ; Neoplasm Staging ; Lung Neoplasms/pathology ; Thymoma/pathology ; Myeloma Proteins ; Thymus Neoplasms/pathology ; Prognosis ; Neoplasms, Glandular and Epithelial/pathology ; Neuroendocrine Tumors/pathology
Chemical Substances	Myeloma Proteins
Language	English
Publishing date	2023-09-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	2432037-7
ISSN	1556-1380 ; 1556-0864
ISSN (online)	1556-1380
ISSN	1556-0864
DOI	10.1016/j.jtho.2023.09.1447
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