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  1. Book: Radiology illustrated: Spine

    Kang, Heung Sik / Lee, Joon Woo / Kwon, Jong Won

    (Radiology illustrated)

    2014  

    Title variant Spine
    Author's details Heung Sik Kang ; Joon Woo Lee ; Jong Won Kwon
    Series title Radiology illustrated
    Keywords Spinal Diseases / radiography ; Spine / radiography
    Language English
    Size XVI, 544 S. : überw. Ill., 29 cm
    Publisher Springer
    Publishing place Berlin u.a.
    Publishing country Germany
    Document type Book
    Note Includes bibliographical references and index
    HBZ-ID HT018519797
    ISBN 978-3-642-35628-5 ; 9783642356292 ; 3-642-35628-1 ; 364235629X
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2015 A 338 available for loan (reading room) Lesesaal EG

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  2. Article ; Online: Correction to "Electrical and Thermal Properties of Surface-Modified Copper Nanowire/Polystyrene Nanocomposites through Latex Blending".

    Eom, Hyeon Sik / Kim, Dong Won / Jang, Keon-Soo / Lee, Seong Jae

    ACS omega

    2024  Volume 9, Issue 4, Page(s) 5080–5081

    Abstract: This corrects the article DOI: 10.1021/acsomega.3c06775.]. ...

    Abstract [This corrects the article DOI: 10.1021/acsomega.3c06775.].
    Language English
    Publishing date 2024-01-19
    Publishing country United States
    Document type Published Erratum
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.3c09978
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: ctDNA predicts clinical T1a to pathological T3a upstaging after partial nephrectomy.

    Park, Jee Soo / Kim, Hongkyung / Jang, Won Sik / Kim, Jongchan / Ham, Won Sik / Lee, Seung-Tae

    Cancer science

    2024  

    Abstract: Most patients diagnosed with clear cell renal cell carcinoma (ccRCC) are also detected with small and organ-confined tumors, and the majority of these are classified as clinical tumor stage 1a (cT1a). A considerable proportion of patients with cT1 RCC ... ...

    Abstract Most patients diagnosed with clear cell renal cell carcinoma (ccRCC) are also detected with small and organ-confined tumors, and the majority of these are classified as clinical tumor stage 1a (cT1a). A considerable proportion of patients with cT1 RCC shows tumor upstaging to pathological stage 3a (pT3a), and these patients have worse oncological outcomes. The role of circulating tumor DNA (ctDNA) in RCC has been limited to monitoring treatment response and resistance. Therefore, the present study aimed to evaluate the potential of ctDNA in predicting pT3a upstaging in cT1a ccRCC. We sequenced plasma samples preoperatively collected from 48 patients who had undergone partial nephrectomy for cT1a ccRCC using data from a prospective cohort RCC. The ctDNA were profiled and compared with clinicopathological ccRCC features to predict pT3a upstaging. Associations between ctDNA, tumor complexity, and pT3a upstaging were evaluated. Tumor complexity was assessed using the anatomical classification system. Univariate analysis used chi-squared and Student's t-tests; multivariate analysis considered significant factors from univariate analyses. Of the 48 patients with cT1a ccRCC, 12 (25%) were upstaged to pT3a, with ctDNA detected in 10 (20.8%), predominantly in patients with renal sinus fat invasion (SFI; n = 8). Among the pT3a group, ctDNA was detected in 75%, contrasting with only 2.8% in patients with pT1a (1/36). Detection of ctDNA was the only significant preoperative predictor of pT3a upstaging, especially in SFI. This study is the first to suggest ctDNA as a preoperative predictor of pT3a RCC upstaging from cT1a based on preoperative radiological images.
    Language English
    Publishing date 2024-03-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2115647-5
    ISSN 1349-7006 ; 1349-7006
    ISSN (online) 1349-7006
    ISSN 1349-7006
    DOI 10.1111/cas.16146
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Three new phthalide derivatives from culture broth of Dentipellis fragilis and their cytotoxic activities.

    Ki, Dae-Won / Choi, Dae-Cheol / Won, Yeong-Seon / Lee, Seung-Jae / Kim, Young-Hee / Lee, In-Kyoung / Yun, Bong-Sik

    The Journal of antibiotics

    2024  

    Abstract: Three new phthalide derivatives (1‒3) together with two known compounds, erinaceolactone B (4) and hericerin III (5), were isolated from the culture broth of Dentipellis fragilis. The chemical structures of 1‒5 were determined by analyses of their 1D-, ... ...

    Abstract Three new phthalide derivatives (1‒3) together with two known compounds, erinaceolactone B (4) and hericerin III (5), were isolated from the culture broth of Dentipellis fragilis. The chemical structures of 1‒5 were determined by analyses of their 1D-, 2D-NMR, and MS. The absolute configuration of 1 was determined by CD analysis. The isolated compounds were assessed for their cytotoxic activities against A549, DU145, HCT116, and HT1080 cancer cell lines. Compounds 1‒5 showed strong cytotoxic activities against DU145, with IC
    Language English
    Publishing date 2024-03-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 390800-8
    ISSN 1881-1469 ; 0021-8820 ; 0368-3532
    ISSN (online) 1881-1469
    ISSN 0021-8820 ; 0368-3532
    DOI 10.1038/s41429-024-00720-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 207: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Engineered ball-milled colloidal activated carbon material for advanced oxidation process of ibuprofen: Influencing factors and insights into the mechanism.

    Lee, Sang Hoon / Annamalai, Sivasankar / Shin, Won Sik

    Environmental pollution (Barking, Essex : 1987)

    2023  Volume 322, Page(s) 121023

    Abstract: This study explores a simple and efficient, physically modified ball-milled activated carbon ( ... ...

    Abstract This study explores a simple and efficient, physically modified ball-milled activated carbon (AC
    MeSH term(s) Charcoal ; Ibuprofen ; Peroxides/chemistry ; Oxidation-Reduction
    Chemical Substances Charcoal (16291-96-6) ; Ibuprofen (WK2XYI10QM) ; peroxymonosulfate (22047-43-4) ; Peroxides
    Language English
    Publishing date 2023-01-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 280652-6
    ISSN 1873-6424 ; 0013-9327 ; 0269-7491
    ISSN (online) 1873-6424
    ISSN 0013-9327 ; 0269-7491
    DOI 10.1016/j.envpol.2023.121023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2599: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: Loranthus tanakae

    Lee, Se-Jin / Pak, So-Won / Lee, A Yeong / Kim, Woong-Il / Chae, Sung-Wook / Cho, Young-Kwon / Ko, Je-Won / Kim, Tae-Won / Kim, Jong-Choon / Moon, Byeong Cheol / Seo, Yun-Soo / Shin, In-Sik

    Antioxidants (Basel, Switzerland)

    2024  Volume 13, Issue 4

    Abstract: Asian sand dust (ASD), generally produced in East Asia, including China, Japan, and Korea, directly leads to the development of pulmonary disease and exacerbates underlying pulmonary diseases. ...

    Abstract Asian sand dust (ASD), generally produced in East Asia, including China, Japan, and Korea, directly leads to the development of pulmonary disease and exacerbates underlying pulmonary diseases.
    Language English
    Publishing date 2024-03-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704216-9
    ISSN 2076-3921
    ISSN 2076-3921
    DOI 10.3390/antiox13040419
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: PD-1 inhibitor plus oncolytic vaccinia virus is a safe and effective treatment option for metastatic renal cell carcinoma.

    Park, Jee Soo / Lee, Myung Eun / Kim, Jongchan / Oh, Keunhee / Lee, Namhee / Jung, Minsun / Jang, Won Sik / Ham, Won Sik

    Cancer cell international

    2024  Volume 24, Issue 1, Page(s) 50

    Abstract: Background: Although a combination of immune checkpoint inhibitors (ICIs) is recommended as the first line treatment option for metastatic renal cell carcinoma (mRCC), several immune-related adverse events (irAEs) occur, especially hepatitis. We ... ...

    Abstract Background: Although a combination of immune checkpoint inhibitors (ICIs) is recommended as the first line treatment option for metastatic renal cell carcinoma (mRCC), several immune-related adverse events (irAEs) occur, especially hepatitis. We explored the therapeutic benefits and safety profile of combining oncolytic vaccinia virus, JX-594, with a programmed cell death protein-1 (PD-1) inhibitor.
    Methods: We used early-stage and advanced-stage orthotopic murine mRCC models developed by our group. PD-1 inhibitor monotherapy or a PD-1 inhibitor combined with either JX-594 or a cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) inhibitor were systemically injected through the peritoneum. An immunofluorescence analysis was performed to analyze the tumor immune microenvironment (TIME). irAEs were assessed in terms of hepatitis.
    Results: In the early-stage mRCC model mice, the combination of JX-594 and a PD-1 inhibitor significantly decreased the primary tumor size and number of lung nodules, compared with the ICI combination, but the JX-594 and PD-1 inhibitor combination and ICI combination did not differ significantly in the advanced-stage mRCC model mice. The JX-594 and PD-1 inhibitor combination induced tumor-suppressing TIME changes in both the early- and advanced-stage mRCC models. Furthermore, mice treated with the ICI combination had significantly greater hepatic injuries than those treated with the JX-594 and PD-1 inhibitor combination which was evaluated in early-stage mRCC model.
    Conclusions: The JX-594 and PD-1 inhibitor combination effectively reduced primary tumors and the metastatic burden, similar to ICI combination therapy, through dynamic remodeling of the TIME. Furthermore, hepatitis was significantly decreased in the JX-594 and PD-1 inhibitor combination group, suggesting the potential benefit of that combination for reducing ICI-induced toxicity.
    Language English
    Publishing date 2024-01-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 2091573-1
    ISSN 1475-2867
    ISSN 1475-2867
    DOI 10.1186/s12935-024-03238-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Socioeconomic and Other Risk Factors for Retear after Arthroscopic Surgery for Nontraumatic Rotator Cuff Tear.

    Lee, Jung Sub / Suh, Kuen Tak / Shin, Won Chul / Bae, Jung Yun / Goh, Tae Sik / Jung, Sung Won / Choi, Min-Hyeok / Kang, Suk-Woong

    Medicina (Kaunas, Lithuania)

    2024  Volume 60, Issue 4

    Abstract: Background and Objectives: ...

    Abstract Background and Objectives:
    MeSH term(s) Humans ; Male ; Rotator Cuff Injuries/surgery ; Middle Aged ; Female ; Arthroscopy/methods ; Arthroscopy/statistics & numerical data ; Retrospective Studies ; Risk Factors ; Aged ; Socioeconomic Factors ; Magnetic Resonance Imaging
    Language English
    Publishing date 2024-04-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina60040640
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6270: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Clinical Validation of the Proenkephalin (

    Han, Hyunho / Oh, Tae Jeong / Heo, Ji Eun / Lee, Jongsoo / Jang, Won Sik / Lee, Seung Hwan / Ham, Won Sik / Hwang, Jaehee / An, Sungwhan / Choi, Young-Deuk

    European urology open science

    2024  Volume 62, Page(s) 99–106

    Abstract: Background and objective: To assess the effectiveness of a urine-based proenkephalin (: Methods: We first conducted a retrospective case-control study involving 54 patients with primary BC and 29 healthy individuals. We then prospectively enrolled ... ...

    Abstract Background and objective: To assess the effectiveness of a urine-based proenkephalin (
    Methods: We first conducted a retrospective case-control study involving 54 patients with primary BC and 29 healthy individuals. We then prospectively enrolled 186 patients (January to December 2022) undergoing cystoscopy surveillance after transurethral resection of bladder tumor, of whom 59 had recurrent tumors. We analyzed voided urine samples for
    Key findings and limitations: In the case-control study, the
    Conclusions and clinical implications: The me
    Patient summary: We found that a test used to analyze urine samples showed good performance in detecting recurrence of NMIBC. This noninvasive me
    Language English
    Publishing date 2024-03-07
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 3040546-4
    ISSN 2666-1683 ; 2058-4881
    ISSN (online) 2666-1683
    ISSN 2058-4881
    DOI 10.1016/j.euros.2024.02.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Tip-based Lithography with a Sacrificial Layer.

    Jo, Jeong-Sik / Lee, Jinho / Choi, Chiwon / Jang, Jae-Won

    Small (Weinheim an der Bergstrasse, Germany)

    2024  , Page(s) e2309484

    Abstract: The fabrication of a highly controlled gold (Au) nanohole (NH) array via tip-based lithography is improved by incorporating a sacrificial layer-a tip-crash buffer layer. This inclusion mitigates scratches during the nano-indentation process by employing ... ...

    Abstract The fabrication of a highly controlled gold (Au) nanohole (NH) array via tip-based lithography is improved by incorporating a sacrificial layer-a tip-crash buffer layer. This inclusion mitigates scratches during the nano-indentation process by employing a 300 nm thick poly(methyl methacrylate) layer as a sacrificial layer on top of the Au film. Such a precaution ensures minimal scratches on the Au film, facilitating the creation of sub-50 nm Au NHs with a 15 nm gap between the Au NHs. The precision of this method exceeds that of fabricating Au NHs without a sacrificial layer. Demonstrating its versatility, this Au NH array is utilized in two distinct applications: as a dry etching mask to form a molybdenum disulfide hole array and as a catalyst in metal-assisted chemical etching, resulting in conical-shaped silicon nanostructures. Additionally, a significant electric field is generated when Au nanoparticles (NPs) are placed within the Au NHs. This effect arises from coupling electromagnetic waves, concentrated by the Au NHs and amplified by the Au NPs. A notable result of this configuration is the enhancement factor of surface-enhanced Raman scattering, which is an order of magnitude greater than that observed with just Au NHs and Au NPs alone.
    Language English
    Publishing date 2024-01-29
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2168935-0
    ISSN 1613-6829 ; 1613-6810
    ISSN (online) 1613-6829
    ISSN 1613-6810
    DOI 10.1002/smll.202309484
    Database MEDical Literature Analysis and Retrieval System OnLINE

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