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Article: Corona-Krise: (Wirtschafts-)politische Perspektiven: Die Reflexe aus der Finanzkrise sind nicht genug!

Fritsche, Jan Philipp / Harms, Patrick Christian

Wirtschaftsdienst (Hamburg, Germany : 1949)

2020 Volume 100, Issue 4, Page(s) 266–271

Abstract: The explosion of Covid-19 cases is looming in Germany. The German Society for Epidemiology has warned that the number of cases could soon overshoot the capacity of the healthcare system. This may be true even if Germany follows the 'flatten-the-curve'- ... ...

Title translation	Fix the Supply Side! Demand Stimulus Will Not Cure What Ails.
Abstract	The explosion of Covid-19 cases is looming in Germany. The German Society for Epidemiology has warned that the number of cases could soon overshoot the capacity of the healthcare system. This may be true even if Germany follows the 'flatten-the-curve'- approach to reduce infection rates. A suppression of the virus remains the best solution for the crisis. Supply will suffer as long the virus persists. Until then, demand side measures will not cure the epidemic. Coordinated measures for business that ensure compliance and European debt instruments may be part of a strategy to solve the crisis.
Keywords	covid19
Language	German
Publishing date	2020-04-22
Publishing country	Germany
Document type	English Abstract ; Journal Article
ZDB-ID	202814-1
ISSN	1613-978X ; 0043-6275
ISSN (online)	1613-978X
ISSN	0043-6275
DOI	10.1007/s10273-020-2630-6
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Book ; Online ; Thesis: Macroeconomic Policy under Uncertainty and Inequality

Fritsche, Jan Philipp [Verfasser] / Menkhoff, Lukas [Gutachter] / Fratzscher, Marcel [Gutachter]

2022

Author's details	Jan Philipp Fritsche ; Gutachter: Lukas Menkhoff, Marcel Fratzscher
Keywords	Wirtschaft ; Economics
Subject code	sg330
Language	English
Publisher	Humboldt-Universität zu Berlin
Publishing place	Berlin
Document type	Book ; Online ; Thesis
Database	Digital theses on the web

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Article: Fix the Supply Side! Demand Stimulus Will Not Cure What Ails/ Corona-Krise: (Wirtschafts-)politische Perspektiven: Die Reflexe aus der Finanzkrise sind nicht genug!

Fritsche, Jan Philipp / Harms, Patrick Christian

Wirtschaftsdienst

Abstract	The explosion of Covid-19 cases is looming in Germany. The German Society for Epidemiology has warned that the number of cases could soon overshoot the capacity of the healthcare system. This may be true even if Germany follows the ‘flatten-the-curve’- approach to reduce infection rates. A suppression of the virus remains the best solution for the crisis. Supply will suffer as long the virus persists. Until then, demand side measures will not cure the epidemic. Coordinated measures for business that ensure compliance and European debt instruments may be part of a strategy to solve the crisis.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #135774
Database	COVID19

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Article ; Online: Corona-Krise

Fritsche, Jan Philipp / Harms, Patrick Christian

(Wirtschafts-)politische Perspektiven. Die Reflexe aus der Finanzkrise sind nicht genug!

2020

Abstract: Die Deutsche Gesellschaft für Epidemiologie warnte, dass die Zahl der COVID-19-Fälle schon bald die Kapazität des Gesundheitssystems übersteigen könnte. In Deutschland und weltweit droht eine schwere Rezession aufgrund eines externen Schocks. Mögliche ... ...

Abstract	Die Deutsche Gesellschaft für Epidemiologie warnte, dass die Zahl der COVID-19-Fälle schon bald die Kapazität des Gesundheitssystems übersteigen könnte. In Deutschland und weltweit droht eine schwere Rezession aufgrund eines externen Schocks. Mögliche Szenarien zur Bekämpfung der Krise zeigen, dass drastische Maßnahmen zur Eindämmung des Virus die beste Lösung für die Krise bleiben. Die Entwicklungen unterscheiden sich fundamental von denen der globalen Finanzkrise 2008. Während der Euroraum in Bezug auf Liquiditäts- und Finanzhilfen für Unternehmen und Staaten bereits besser gewappnet ist als noch 2009, fehlt die Praxis in der Zusammenarbeit von Gesundheitsforschung und Wirtschaftspolitik. Maßnahmen auf der Nachfrageseite werden die Epidemie kurzfristig nicht heilen. Eine koordinierte Finanzpolitik und gemeinsame europäische Anleihen können vor allem gefährdete Staaten schützen. The explosion of Covid-19 cases is looming in Germany. The German Society for Epidemiology has warned that the number of cases could soon overshoot the capacity of the healthcare system. This may be true even if Germany follows the 'flatten-the-curve'- approach to reduce infection rates. A suppression of the virus remains the best solution for the crisis. Supply will suffer as long the virus persists. Until then, demand side measures will not cure the epidemic. Coordinated measures for business that ensure compliance and European debt instruments may be part of a strategy to solve the crisis.
Keywords	ddc:330 ; E50 ; E60 ; I10 ; covid19
Subject code	801
Language	German
Publisher	Heidelberg: Springer
Publishing country	de
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Passenger Gene Coamplifications Create Collateral Therapeutic Vulnerabilities in Cancer.

Bei, Yi / Bramé, Luca / Kirchner, Marieluise / Fritsche-Guenther, Raphaela / Kunz, Severine / Bhattacharya, Animesh / Rusu, Mara-Camelia / Gürgen, Dennis / Dubios, Frank P B / Köppke, Julia K C / Proba, Jutta / Wittstruck, Nadine / Sidorova, Olga Alexandra / Chamorro González, Rocío / Dorado Garcia, Heathcliff / Brückner, Lotte / Xu, Robin / Giurgiu, Mădălina / Rodriguez-Fos, Elias /

Yu, Qinghao / Spanjaard, Bastiaan / Koche, Richard P / Schmitt, Clemens A / Schulte, Johannes H / Eggert, Angelika / Haase, Kerstin / Kirwan, Jennifer / Hagemann, Anja I H / Mertins, Philipp / Dörr, Jan R / Henssen, Anton G

Cancer discovery

2024 Volume 14, Issue 3, Page(s) 492–507

Abstract: DNA amplifications in cancer do not only harbor oncogenes. We sought to determine whether passenger coamplifications could create collateral therapeutic vulnerabilities. Through an analysis of >3,000 cancer genomes followed by the interrogation of CRISPR- ...

Abstract	DNA amplifications in cancer do not only harbor oncogenes. We sought to determine whether passenger coamplifications could create collateral therapeutic vulnerabilities. Through an analysis of >3,000 cancer genomes followed by the interrogation of CRISPR-Cas9 loss-of-function screens across >700 cancer cell lines, we determined that passenger coamplifications are accompanied by distinct dependency profiles. In a proof-of-principle study, we demonstrate that the coamplification of the bona fide passenger gene DEAD-Box Helicase 1 (DDX1) creates an increased dependency on the mTOR pathway. Interaction proteomics identified tricarboxylic acid (TCA) cycle components as previously unrecognized DDX1 interaction partners. Live-cell metabolomics highlighted that this interaction could impair TCA activity, which in turn resulted in enhanced mTORC1 activity. Consequently, genetic and pharmacologic disruption of mTORC1 resulted in pronounced cell death in vitro and in vivo. Thus, structurally linked coamplification of a passenger gene and an oncogene can result in collateral vulnerabilities. Significance: We demonstrate that coamplification of passenger genes, which were largely neglected in cancer biology in the past, can create distinct cancer dependencies. Because passenger coamplifications are frequent in cancer, this principle has the potential to expand target discovery in oncology. This article is featured in Selected Articles from This Issue, p. 384.
MeSH term(s)	Humans ; Oncogenes ; Neoplasms/genetics ; Medical Oncology ; Cell Death ; Mechanistic Target of Rapamycin Complex 1/genetics
Chemical Substances	Mechanistic Target of Rapamycin Complex 1 (EC 2.7.11.1)
Language	English
Publishing date	2024-01-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	2625242-9
ISSN	2159-8290 ; 2159-8274
ISSN (online)	2159-8290
ISSN	2159-8274
DOI	10.1158/2159-8290.CD-23-1189
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Article ; Online: EORTC progression score identifies patients at high risk of cancer-specific mortality after radical cystectomy for secondary muscle-invasive bladder cancer.

May, Matthias / Burger, Maximilian / Brookman-May, Sabine / Stief, Christian G / Fritsche, Hans-Martin / Roigas, Jan / Zacharias, Mario / Bader, Markus / Mandel, Philipp / Gilfrich, Christian / Seitz, Michael / Tilki, Derya

Clinical genitourinary cancer

2014 Volume 12, Issue 4, Page(s) 278–286

Abstract: Background: The aim of this study was to develop a risk stratification of patients with muscle-invasive bladder cancer (MIBC) after radical cystectomy (RC). For this purpose, we compared the cancer-specific mortality (CSM) of patients with primary MIBC ... ...

Abstract	Background: The aim of this study was to develop a risk stratification of patients with muscle-invasive bladder cancer (MIBC) after radical cystectomy (RC). For this purpose, we compared the cancer-specific mortality (CSM) of patients with primary MIBC and patients with secondary MIBC in different risk groups according to the European Organisation for Research and Treatment of Cancer (EORTC) progression score. Patients and methods: The records of 521 consecutive patients treated with RC for clinical MIBC according to transurethral resection of bladder cancer (TURBT) diagnosis were reviewed. Of the 521 patients, 399 (76.6%) had primary MIBC (study group 1 [SG1]) and 122 (23.4%) had secondary MIBC (study group 2 [SG2]). Patients in SG2 were stratified into risk groups according to the results of the first and last TURBT in non-MIBC using the EORTC progression score. Results: CSM for patients with primary and secondary MIBC did not differ significantly. Patients in SG2 with the highest risk for tumor stage progression at time of the first and last TURBT in non-MIBC showed a significantly higher CSM after RC compared with patients with low-to-intermediate risk and compared with patients in SG1. In multivariable analyses, stage pT 3/4 (hazard ratio [HR], 2.12; P < .001), lymphovascular invasion (LVI) (HR, 3.47; P < .001), female sex (HR, 1.35; P = .048), and time from diagnosis of MIBC to RC > 90 days (HR, 2.07; P < .001) were significantly associated with higher CSM. Conclusion: Risk stratification by the EORTC progression score can help to identify those patients with the highest risk of CSM after progression to MIBC and thus enable us to offer these patients a multimodal treatment. Our results need to be verified in large prospective studies.
MeSH term(s)	Aged ; Cystectomy/mortality ; Disease Progression ; Female ; Follow-Up Studies ; Humans ; Male ; Muscle Neoplasms/mortality ; Muscle Neoplasms/pathology ; Muscle Neoplasms/surgery ; Neoplasm Grading ; Neoplasm Invasiveness ; Neoplasm Staging ; Prognosis ; Risk Assessment ; Survival Rate ; Urinary Bladder Neoplasms/mortality ; Urinary Bladder Neoplasms/pathology ; Urinary Bladder Neoplasms/surgery
Language	English
Publishing date	2014-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	2225121-2
ISSN	1938-0682 ; 1558-7673
ISSN (online)	1938-0682
ISSN	1558-7673
DOI	10.1016/j.clgc.2013.11.014
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Article ; Online: Comparative analysis of the effect of prostatic invasion patterns on cancer-specific mortality after radical cystectomy in pT4a urothelial carcinoma of the bladder.

Vallo, Stefan / Gilfrich, Christian / Burger, Maximilian / Volkmer, Björn / Boehm, Katharina / Rink, Michael / Chun, Felix K / Roghmann, Florian / Novotny, Vladimir / Mani, Jens / Brisuda, Antonin / Mayr, Roman / Stredele, Regina / Noldus, Joachim / Schnabel, Marco / May, Matthias / Fritsche, Hans-Martin / Pycha, Armin / Martini, Thomas /

Wirth, Manfred / Roigas, Jan / Bastian, Patrick J / Nuhn, Philipp / Dahlem, Roland / Haferkamp, Axel / Fisch, Margit / Aziz, Atiqullah

Urologic oncology

2016 Volume 34, Issue 10, Page(s) 432.e1–8

Abstract: Purpose: To evaluate the prognostic relevance of different prostatic invasion patterns in pT4a urothelial carcinoma of the bladder (UCB) after radical cystectomy.: Materials and methods: Our study comprised a total of 358 men with pT4a UCB. Patients ... ...

Abstract	Purpose: To evaluate the prognostic relevance of different prostatic invasion patterns in pT4a urothelial carcinoma of the bladder (UCB) after radical cystectomy. Materials and methods: Our study comprised a total of 358 men with pT4a UCB. Patients were divided in 2 groups-group A with stromal infiltration of the prostate via the prostatic urethra with additional muscle-invasive UCB (n = 121, 33.8%) and group B with continuous infiltration of the prostate through the entire bladder wall (n = 237, 66.2%). The effect of age, tumor grade, carcinoma in situ, lymphovascular invasion, soft tissue surgical margin, lymph node metastases, administration of adjuvant chemotherapy, and prostatic invasion patterns on cancer-specific mortality (CSM) was evaluated using competing-risk regression analysis. Decision curve analysis was used to evaluate the net benefit of including the variable invasion pattern within our model. Results: The estimated 5-year CSM-rates for group A and B were 50.1% and 66.0%, respectively. In multivariable competing-risk analysis, lymph node metastases (hazard ratio [HR] = 1.73, P<0.001), lymphovascular invasion (HR = 1.62, P = 0.0023), soft tissue surgical margin (HR = 1.49, P = 0.026), absence of adjuvant chemotherapy (HR = 2.11, P<0.001), and tumor infiltration of the prostate by continuous infiltration of the entire bladder wall (HR = 1.37, P = 0.044) were significantly associated with a higher risk for CSM. Decision curve analysis showed a net benefit of our model including the variable invasion pattern. Conclusions: Continuous infiltration of the prostate through the entire bladder wall showed an adverse effect on CSM. Besides including these patients into clinical trials for an adjuvant therapy, we recommend including prostatic invasion patterns in predictive models in pT4a UCB in men.
Language	English
Publishing date	2016-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	1336505-8
ISSN	1873-2496 ; 1078-1439
ISSN (online)	1873-2496
ISSN	1078-1439
DOI	10.1016/j.urolonc.2016.05.008
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Article ; Online: Gender-specific differences in cancer-specific survival after radical cystectomy for patients with urothelial carcinoma of the urinary bladder in pathologic tumor stage T4a.

May, Matthias / Bastian, Patrick J / Brookman-May, Sabine / Fritsche, Hans-Martin / Tilki, Derya / Otto, Wolfgang / Bolenz, Christian / Gilfrich, Christian / Trojan, Lutz / Herrmann, Edwin / Moritz, Rudolf / Tiemann, Arne / Müller, Stefan C / Ellinger, Jörg / Buchner, Alexander / Stief, Christian G / Wieland, Wolf F / Höfner, Thomas / Hohenfellner, Markus /

Haferkamp, Axel / Roigas, Jan / Zacharias, Mario / Nuhn, Philipp / Burger, Maximilian

Urologic oncology

2013 Volume 31, Issue 7, Page(s) 1141–1147

Abstract: Background: Bladder cancer (UCB) staged pT4a show heterogeneous outcome after radical cystectomy (RC). No risk model has been established to date. Despite gender-specific differences, no comparative studies exist for this tumor stage.: Materials and ... ...

Abstract	Background: Bladder cancer (UCB) staged pT4a show heterogeneous outcome after radical cystectomy (RC). No risk model has been established to date. Despite gender-specific differences, no comparative studies exist for this tumor stage. Materials and methods: Cancer-specific survival (CSS) of 245 UCB patients without neoadjuvant chemotherapy staged pT4a, pN0-2, M0 after RC were analyzed in a retrospective multi-center study. Seventeen patients were excluded from further analysis due to carcinoma in situ (CIS) of the prostatic urethra and/or positive surgical margins. Average follow-up period was 30 months (IQR: 14-45). The influence of different clinical and histopathologic variables on CSS was determined through uni- and multivariate Cox regression analyses. Two risk groups were generated using factors with independent effect in multivariate models. Internal validity of the prediction model was evaluated by bootstrapping. Results: Eighty-four percent of the patients (n = 192) were male; 72% (n = 165) showed lymphovascular invasion (LVI). The 5-year CSS rate was 31%, and significantly different between male and female (35% vs. 15%, P = 0.003). Multivariate Cox regression modeling, female gender (HR = 1.83, P = 0.008), LVI (HR = 1.92, P = 0.005), and absence of adjuvant chemotherapy (HR = 0.61, P = 0.020) significantly worsened CSS. Two risk groups were generated using these 3 criteria, which differed significantly between each other in CSS (5-year-CSS: 46% vs. 12%, P < 0.001). The c-index value of the risk model was 0.61 (95% CI: 0.53-0.68, P < 0.001). Conclusions: Prognosis in UCB staged pT4a is heterogeneous. Female gender and LVI are adverse factors. Adjuvant chemotherapy seems to improve outcome. The present analysis establishes the first risk model for this demanding tumor stage.
MeSH term(s)	Aged ; Carcinoma, Transitional Cell/mortality ; Carcinoma, Transitional Cell/pathology ; Carcinoma, Transitional Cell/surgery ; Chemotherapy, Adjuvant ; Cystectomy/methods ; Female ; Humans ; Male ; Middle Aged ; Multivariate Analysis ; Neoplasm Staging ; Outcome Assessment (Health Care)/statistics & numerical data ; Prognosis ; Proportional Hazards Models ; Regression Analysis ; Retrospective Studies ; Sex Factors ; Survival Rate ; Urinary Bladder/drug effects ; Urinary Bladder/pathology ; Urinary Bladder/surgery ; Urinary Bladder Neoplasms/mortality ; Urinary Bladder Neoplasms/pathology ; Urinary Bladder Neoplasms/surgery
Language	English
Publishing date	2013-10
Publishing country	United States
Document type	Journal Article ; Multicenter Study
ZDB-ID	1336505-8
ISSN	1873-2496 ; 1078-1439
ISSN (online)	1873-2496
ISSN	1078-1439
DOI	10.1016/j.urolonc.2011.09.011
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Article ; Online: External validation of a risk model to predict recurrence-free survival after radical cystectomy in patients with pathological tumor stage T3N0 urothelial carcinoma of the bladder.

The Journal of urology

2012 Volume 187, Issue 4, Page(s) 1210–1214

Abstract: Purpose: Patients with stage pT3N0 urothelial bladder cancer vary in outcome after radical cystectomy. To improve prognosis estimation a model was recently developed that defines 3 risk groups for recurrence-free survival based on pT substaging, ... ...

Abstract	Purpose: Patients with stage pT3N0 urothelial bladder cancer vary in outcome after radical cystectomy. To improve prognosis estimation a model was recently developed that defines 3 risk groups for recurrence-free survival based on pT substaging, lymphovascular invasion and positive surgical margin. We present what is to our knowledge the first external validation of this risk model. Materials and methods: Analogous to the risk model derivation cohort our study group comprised 472 patients with stage pT3, pN0, cM0 disease without perioperative chemotherapy and with a median followup of 42 months (IQR 20-75). The primary end point was recurrence-free survival. The effect of variables was determined by univariate and multivariate Cox regression analysis, and predictive accuracy was determined by ROC analysis. Results: Stage pT3aN0 and pT3bN0 cases showed significantly different recurrence-free survival after 5 years (51% vs 29%, p<0.001). In the multivariate Cox model pT3 substage (HR 1.86, p<0.001), lymphovascular invasion (HR 1.48, p=0.002), positive surgical margins (HR 1.90, p=0.030) and patient age with a dichotomy at 70 years (HR 1.51, p=0.001) had an independent effect on recurrence-free survival. In the low (221 patients or 47%), intermediate (184 or 39%) and high (67 or 14%) risk groups the 5-year recurrence-free survival rate was 55%, 45% and 13%, respectively (p<0.001). The concordance index of the risk model to predict recurrence-free survival was 0.64 (95% CI 0.59-0.69). Conclusions: This user friendly risk model can be recommended to estimate prognosis in patients with stage pT3N0 after radical cystectomy. Patients at high risk showed clearly compromised recurrence-free survival and should be included in adjuvant therapy studies.
MeSH term(s)	Aged ; Carcinoma, Transitional Cell/pathology ; Carcinoma, Transitional Cell/surgery ; Cystectomy ; Disease-Free Survival ; Forecasting ; Humans ; Models, Statistical ; Neoplasm Staging ; Retrospective Studies ; Risk Assessment ; Urinary Bladder Neoplasms/pathology ; Urinary Bladder Neoplasms/surgery
Language	English
Publishing date	2012-04
Publishing country	United States
Document type	Journal Article ; Multicenter Study ; Validation Studies
ZDB-ID	3176-8
ISSN	1527-3792 ; 0022-5347
ISSN (online)	1527-3792
ISSN	0022-5347
DOI	10.1016/j.juro.2011.11.104
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Article ; Online: Analysis of sex differences in cancer-specific survival and perioperative mortality following radical cystectomy: results of a large German multicenter study of nearly 2500 patients with urothelial carcinoma of the bladder.

Otto, Wolfgang / May, Matthias / Fritsche, Hans-Martin / Dragun, Duska / Aziz, Atiqullah / Gierth, Michael / Trojan, Lutz / Herrmann, Edwin / Moritz, Rudolf / Ellinger, Jörg / Tilki, Derya / Buchner, Alexander / Höfner, Thomas / Brookman-May, Sabine / Nuhn, Philipp / Gilfrich, Christian / Roigas, Jan / Zacharias, Mario / Denzinger, Stefan /

Hohenfellner, Markus / Haferkamp, Axel / Müller, Stefan C / Kocot, Arkadius / Riedmiller, Hubertus / Wieland, Wolf F / Stief, Christian G / Bastian, Patrick J / Burger, Maximilian

Gender medicine. official journal of the Partnership for Gender-Specific Medicine at Columbia University

2012 Volume 9, Issue 6, Page(s) 481–489

Abstract: Background: Outcome of patients with urothelial carcinoma of the bladder (UCB) varies between sexes. Although overall incidence is higher in men, cancer-specific survival (CSS) has been suggested to be lower in women. Although the former effect is ... ...

Abstract	Background: Outcome of patients with urothelial carcinoma of the bladder (UCB) varies between sexes. Although overall incidence is higher in men, cancer-specific survival (CSS) has been suggested to be lower in women. Although the former effect is attributed to greater exposure to carcinogens in men, the latter has not been elucidated. Objectives: The aim of the study was to identify sex-specific outcomes based on one of the largest databases of patients with UCB who underwent radical cystectomy (RC). Methods: This retrospective multicenter series comprised 2483 patients in Stage M0 who underwent RC for UCB from 1989 to 2008; 20.4% of patients were women. The impact of sex on CSS in the entire study group and in specific subgroups was analyzed. The median follow-up time was 42 months (interquartile range, 21-79). Results: Histopathologic criteria of pathologic tumor (pT), pathologic nodal (pN), grade, lymphovascular invasion (LVI), and associated carcinoma in situ (CIS) of the study did not differ between sexes. The percentage of female patients increased over time. Five-year CSS in female patients was significantly lower than in male patients (60% vs 66%; P = 0.005). In multivariate analysis adjusted to other covariates, tumor stage ≥pT3 (hazard ratio [HR] = 2.44; P < 0.001), positive pN status (HR = 1.91; P < 0.001), LVI (HR = 1.48; P < 0.001), lower count of lymph nodes removed (HR = 0.98; P = 0.002), older age (HR = 1.01; P < 0.001), and female gender (HR = 1.26; P = 0.011) had an independent impact on CSS. Deterioration of CSS in female patients was pronounced when LVI was present (HR = 1.57; P < 0.001) and when RC was performed in the earlier time period (HR = 2.44; P < 0.001). However, women showed significantly lower perioperative mortality (within 90 days after RC) compared with men. Conclusions: After RC for UCB, cancer-specific mortality was higher in female patients; this disadvantage was more pronounced in earlier time periods. In addition, worse outcome of women with verified LVI was shown to be comparable with men. These findings were suggestive of different tumor biology and potentially unequal access to timely RC in earlier time periods because of reduced awareness of UCB in women. Further studies are required to improve UCB outcome in both sexes, notably in female patients.
MeSH term(s)	Age Factors ; Aged ; Blood Vessels/pathology ; Carcinoma/mortality ; Carcinoma/secondary ; Carcinoma/surgery ; Cystectomy ; Female ; Germany ; Humans ; Kaplan-Meier Estimate ; Lymphatic Metastasis ; Lymphatic Vessels/pathology ; Male ; Middle Aged ; Multivariate Analysis ; Neoplasm Invasiveness ; Neoplasm Staging ; Proportional Hazards Models ; Retrospective Studies ; Sex Factors ; Survival Rate ; Urinary Bladder Neoplasms/mortality ; Urinary Bladder Neoplasms/pathology ; Urinary Bladder Neoplasms/surgery
Language	English
Publishing date	2012-12-06
Publishing country	United States
Document type	Journal Article ; Multicenter Study
ZDB-ID	2171408-3
ISSN	1878-7398 ; 1550-8579
ISSN (online)	1878-7398
ISSN	1550-8579
DOI	10.1016/j.genm.2012.11.001
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