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  1. Article ; Online: Corona and clergy - The missing link for effective social distancing in Pakistan: Time for some unpopular decisions.

    Mubarak, Naeem

    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

    2020  Volume 95, Page(s) 431–432

    Keywords covid19
    Language English
    Publishing date 2020-04-30
    Publishing country Canada
    Document type Letter
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2020.04.067
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4516: Show issues Location:
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  2. Article ; Online: Corona and clergy – The missing link for effective social distancing in Pakistan

    Naeem Mubarak

    International Journal of Infectious Diseases, Vol 95, Iss , Pp 431-

    Time for some unpopular decisions

    2020  Volume 432

    Keywords COVID-19 ; Social distancing ; Religious congregations ; Public perception ; Clergy ; Health policy ; Infectious and parasitic diseases ; RC109-216 ; covid19
    Language English
    Publishing date 2020-06-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Accuracy of MRI in Detecting 1p/19q Co-deletion Status of Gliomas: A Single-Center Retrospective Study.

    Naeem, Adnan / Aziz, Namrah / Nasir, Manal / Rangwala, Hussain Sohail / Fatima, Hareer / Mubarak, Fatima

    Cureus

    2024  Volume 16, Issue 1, Page(s) e51863

    Abstract: Background Oligodendrogliomas, rare brain tumors in the frontal lobe's white matter, are reshaped by molecular markers like isocitrate dehydrogenase mutations and 1p/19q co-deletion, influencing treatment outcomes. Despite the initial indolence, these ... ...

    Abstract Background Oligodendrogliomas, rare brain tumors in the frontal lobe's white matter, are reshaped by molecular markers like isocitrate dehydrogenase mutations and 1p/19q co-deletion, influencing treatment outcomes. Despite the initial indolence, these tumors pose a significant risk, with a median survival of 10-12 years. Non-invasive alternatives, such as magnetic resonance imaging (MRI) for assessing T2-fluid-attenuated inversion recovery (FLAIR) mismatch and calcifications, provide insights into molecular subtypes and aid prognosis. Our study explored these features to predict the oligodendroglioma status and refine patient management to improve outcomes. Methods In this retrospective study, patient data identified patients with suspected central nervous system tumors undergoing MRI, revealing low-grade gliomas. Surgical biopsy and 1p/19q fluorescence in situ hybridization confirmed the co-deletion status. MRI was used to assess various morphological features. Statistical analyses included x2 tests, Fisher's exact tests, Kruskal-Wallis tests, and binary logistic regression models, with significance set at p < 0.05. Results Seventy-three patients (median age, 37 years) were stratified according to 1p/19q co-deletion. Most (61.6%) were 18-40 years old and mostly male (67.1%). Co-deletion cases, primarily frontal lobe lesions (67.6%), were unilateral (88.2%), with 55.9% non-circumscribed margins and 58.8% ill-defined contours. Smooth contrast enhancement and no necrosis were observed in 48.1% of 1p/19q co-deletion cases. Logistic regression analysis showed a significant association between ill-defined/irregular contours and 1p/19q co-deletion. Fisher's exact test confirmed this but raised concerns about the small sample size influencing the conclusions. Conclusions This study established a significant link between glioma tumor contour characteristics, particularly irregular and ill-defined contours, and the likelihood of 1p/19q co-deletion. Our findings underscore the clinical relevance of using tumor contours in treatment decisions and prognosis assessments.
    Language English
    Publishing date 2024-01-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.51863
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Stress and depression among students: Are we doing enough?

    Tariq, Sundus / Tariq, Saba / Mubarak, Naeem

    Pakistan journal of medical sciences

    2022  Volume 38, Issue 8, Page(s) 2056–2057

    Language English
    Publishing date 2022-11-18
    Publishing country Pakistan
    Document type Editorial
    ZDB-ID 2032827-8
    ISSN 1681-715X ; 1682-024X ; 1017-4699
    ISSN (online) 1681-715X
    ISSN 1682-024X ; 1017-4699
    DOI 10.12669/pjms.38.8.7076
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3948: Show issues Location:
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  7. Article ; Online: Advanced Polymers and Recent Advancements on Gastroretentive Drug Delivery System; A Comprehensive Review.

    Waqar, Muhammad Ahsan / Khan, Asad Majeed / Mubarak, Naeem / Khan, Rabeel / Shaheen, Farwa / Shabbir, Afshan

    Journal of drug targeting

    2024  , Page(s) 1–33

    Abstract: Oral route of drug administration is typically the initial option for drug administration because it is both practical and affordable. However, major drawback of this route includes the release of drug at a specified place thus reduces the ... ...

    Abstract Oral route of drug administration is typically the initial option for drug administration because it is both practical and affordable. However, major drawback of this route includes the release of drug at a specified place thus reduces the bioavailability. This could be overcome by utilizing the gastroretentive drug delivery system (GRRDS). Prolonged stomach retention improves bioavailability and increases solubility for medicines that are unable to dissolve in high pH environments. Many recent advancements in the floating, bio adhesive, magnetic, expandable, raft forming and ion exchange systems have been made that had led towards advanced form of drug delivery. From the past few years, floating drug delivery system has been most commonly utilized for the delivery of drug in a delayed manner. Various polymers have been utilized for manufacturing of these systems, including alginates, chitosan, pectin, carrageenan's, xanthan gum, hydroxypropyl cellulose, carbomer, polyethylene oxide and sodium carboxy methyl cellulose. Chitosan, pectin and xanthan gum have been found to be most commonly used polymers in the manufacturing of drug inclusion complex for gastroretentive drug delivery. This study aimed to define various types and advanced polymers as well as also highlights recent advances and future perspectives of gastroretentive drug delivery system.
    Language English
    Publishing date 2024-04-23
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1187110-6
    ISSN 1029-2330 ; 1061-186X
    ISSN (online) 1029-2330
    ISSN 1061-186X
    DOI 10.1080/1061186X.2024.2347366
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4481: Show issues Location:
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  8. Article ; Online: Religious tourism and mass religious gatherings - The potential link in the spread of COVID-19. Current perspective and future implications.

    Mubarak, Naeem / Zin, Che Suraya

    Travel medicine and infectious disease

    2020  Volume 36, Page(s) 101786

    Keywords covid19
    Language English
    Publishing date 2020-06-09
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 2170891-5
    ISSN 1873-0442 ; 1477-8939
    ISSN (online) 1873-0442
    ISSN 1477-8939
    DOI 10.1016/j.tmaid.2020.101786
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    Zs.A 6236: Show issues Location:
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  9. Article ; Online: The influence of pharmacist-led collaborative care on clinical outcomes in type 2 diabetes mellitus: a multicenter randomized control trial.

    Iqbal, Muhammad Zahid / Alqahtani, Saad Saeed / Mubarak, Naeem / Shahid, Sara / Mohammed, Rafiuddin / Mustafa, Abid / Khan, Amer Hayat / Iqbal, Muhammad Shahid

    Frontiers in public health

    2024  Volume 12, Page(s) 1323102

    Abstract: Background: Health care providers are mandated to deliver specialized care for the treatment and control of type 2 diabetes mellitus. In Malaysia, Diabetes Medication Therapy Adherence Clinics (DMTAC) in tertiary hospitals have designated pharmacists to ...

    Abstract Background: Health care providers are mandated to deliver specialized care for the treatment and control of type 2 diabetes mellitus. In Malaysia, Diabetes Medication Therapy Adherence Clinics (DMTAC) in tertiary hospitals have designated pharmacists to administer these services.
    Objective: To assess the effects of pharmacist-led interventions within DMTAC on the outcomes of patients with type 2 diabetes mellitus in two distinct hospitals in Kedah, Malaysia.
    Methods: Patients with type 2 diabetes were randomly selected from the two hospitals included in this study. The study population was divided into two equal groups. The control group consisted of 200 patients receiving routine care from the hospitals. On the other hand, the intervention group included those patients with type 2 diabetes (200), who received separate counseling sessions from pharmacists in the DMTAC departments along with the usual treatment. The study lasted 1 year, during which both study groups participated in two distinct visits.
    Results: Parametric data were analyzed by a paired
    Conclusion: Based on the findings of the current study it has been proven that the involvement of pharmacists leads to improved control of diabetes mellitus. Therefore, it is recommended that the government initiate DMTAC services in both private and government hospitals and clinics throughout Malaysia. Furthermore, future studies should assess the impact of pharmacist interventions on other chronic conditions, including but not limited to asthma, arthritis, cancer, Alzheimer's disease, and dementia.
    MeSH term(s) Humans ; Diabetes Mellitus, Type 2/drug therapy ; Pharmacists ; Hypoglycemic Agents/therapeutic use ; Glycated Hemoglobin ; Medication Adherence
    Chemical Substances Hypoglycemic Agents ; Glycated Hemoglobin
    Language English
    Publishing date 2024-02-27
    Publishing country Switzerland
    Document type Randomized Controlled Trial ; Multicenter Study ; Journal Article
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2024.1323102
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Parents' refusal to vitamin-K supplementation among neonates and its association with vaccine refusal: A systematic review and meta-analysis.

    Khan, Tahir Mehmood / Mubarak, Naeem / Suleimen, Amal / Jaber, Ammar Ali Saleh / Baig, Mirza Rafi

    JPMA. The Journal of the Pakistan Medical Association

    2023  Volume 72, Issue 11, Page(s) 2251–2258

    Abstract: Objective: This systematic review and meta-analysis aims to estimate the prevalence of neonatal vitamin K prophylaxis refusal among parents and its possible association with subsequent vaccine hesitancy or refusal.: Methods: The databases searched ... ...

    Abstract Objective: This systematic review and meta-analysis aims to estimate the prevalence of neonatal vitamin K prophylaxis refusal among parents and its possible association with subsequent vaccine hesitancy or refusal.
    Methods: The databases searched included PubMed, Cochrane Library, Embase via Ovid, CINAHL Plus and Medline via EBSCOhost, ProQuest and PsycINFO from inception to 31 August 2017. Keywords, such as "vitamin K", "refusal", "decline", "hesitancy", and "vaccination" were used to identify potential studies. Analysis of proportions was conducted, while odd ratios and relative risks were estimated using the random effect model.
    Results: Of the 2216 studies identified, 8(0.36%) were subjected to qualitative analysis; 4(50%) retrospective cohort studies and 4(50%) cross-sectional studies. Overall, 6(75%) studies were of good quality, while 2(25%) were ranked as of fair quality. Of the 273,714 parents, 3,136(1.14%) refused to opt for the vitamin K prophylaxis. Meta-analysis concluded that refusal to vitamin K prophylaxis was significant among the included studies ((p<0.184).
    Conclusions: The overall risk of refusal to essential vaccination among vitamin K prophylaxis refusal group was 6.45 times compared to the group that accepted vitamin K prophylaxis.
    MeSH term(s) Infant, Newborn ; Humans ; Vitamin K ; Retrospective Studies ; Cross-Sectional Studies ; Treatment Refusal ; Vaccination Refusal ; Parents ; Vitamins ; Dietary Supplements
    Chemical Substances Vitamin K (12001-79-5) ; Vitamins
    Language English
    Publishing date 2023-01-12
    Publishing country Pakistan
    Document type Meta-Analysis ; Systematic Review
    ZDB-ID 603873-6
    ISSN 0030-9982
    ISSN 0030-9982
    DOI 10.47391/JPMA.3914
    Database MEDical Literature Analysis and Retrieval System OnLINE

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