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  1. Article ; Online: Confounding in the hyponatremia, bone mineral density and falls relationship.

    Otelea, Marina Ruxandra

    Romanian journal of internal medicine = Revue roumaine de medecine interne

    2019  Volume 57, Issue 3, Page(s) 207–208

    MeSH term(s) Accidental Falls ; Aged ; Bone Density ; Humans ; Hyponatremia
    Language English
    Publishing date 2019-03-19
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 2015966-3
    ISSN 2501-062X ; 0035-3973 ; 1582-3296
    ISSN (online) 2501-062X
    ISSN 0035-3973 ; 1582-3296
    DOI 10.2478/rjim-2019-0008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 738: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  2. Article ; Online: Confounding in the hyponatremia, bone mineral density and falls relationship

    Otelea Marina Ruxandra

    Romanian Journal of Internal Medicine, Vol 57, Iss 3, Pp 207-

    2019  Volume 208

    Keywords Internal medicine ; RC31-1245
    Language English
    Publishing date 2019-09-01T00:00:00Z
    Publisher Sciendo
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Impaired Melatonin Secretion, Oxidative Stress and Metabolic Syndrome in Night Shift Work.

    Hohor, Sorina / Mandanach, Cristina / Maftei, Andreea / Zugravu, Corina Aurelia / Oțelea, Marina Ruxandra

    Antioxidants (Basel, Switzerland)

    2023  Volume 12, Issue 4

    Abstract: Metabolic syndrome has been associated in many studies with working in shifts. Even if the mechanistic details are not fully understood, forced sleep deprivation and exposure to light, as happens during night shifts, or irregular schedules with late or ... ...

    Abstract Metabolic syndrome has been associated in many studies with working in shifts. Even if the mechanistic details are not fully understood, forced sleep deprivation and exposure to light, as happens during night shifts, or irregular schedules with late or very early onset of the working program, lead to a sleep-wake rhythm misalignment, metabolic dysregulation and oxidative stress. The cyclic melatonin secretion is regulated by the hypothalamic suprachiasmatic nuclei and light exposure. At a central level, melatonin promotes sleep and inhibits wake-signals. Beside this role, melatonin acts as an antioxidant and influences the functionality of the cardiovascular system and of different metabolic processes. This review presents data about the influence of night shifts on melatonin secretion and oxidative stress. Assembling data from epidemiological, experimental and clinical studies contributes to a better understanding of the pathological links between chronodisruption and the metabolic syndrome related to working in shifts.
    Language English
    Publishing date 2023-04-19
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2704216-9
    ISSN 2076-3921
    ISSN 2076-3921
    DOI 10.3390/antiox12040959
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Is Spontaneous Preterm Prelabor of Membrane Rupture Irreversible? A Review of Potentially Curative Approaches.

    Danciu, Bianca Mihaela / Oţelea, Marina Ruxandra / Marincaş, Marian Augustin / Niţescu, Maria / Simionescu, Anca Angela

    Biomedicines

    2023  Volume 11, Issue 7

    Abstract: There is still no curative treatment for the spontaneous preterm prelabor rupture of membranes (sPPROM), the main cause of premature birth. Here, we summarize the most recent methods and materials used for sealing membranes after sPPROM. A literature ... ...

    Abstract There is still no curative treatment for the spontaneous preterm prelabor rupture of membranes (sPPROM), the main cause of premature birth. Here, we summarize the most recent methods and materials used for sealing membranes after sPPROM. A literature search was conducted between 2013 and 2023 on reported newborns after membranes were sealed or on animal or tissue culture models. Fourteen studies describing the outcomes after using an amniopatch, an immunologic sealant, or a mechanical cervical adapter were included. According to these studies, an increase in the volume of amniotic fluid and the lack of chorioamnionitis demonstrate a favorable neonatal outcome, with a lower incidence of respiratory distress syndrome and early neonatal sepsis, even if sealing is not complete and stable. In vivo and in vitro models demonstrated that amniotic stem cells, in combination with amniocytes, can spontaneously repair small defects; because of the heterogenicity of the data, it is too early to draw a thoughtful conclusion. Future therapies should focus on materials and methods for sealing fetal membranes that are biocompatible, absorbable, available, easy to apply, and easily adherent to the fetal membrane.
    Language English
    Publishing date 2023-07-04
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines11071900
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Coronasomnia in Employees without a Direct Contact with COVID-19 Infected Patients in Their Workplace.

    Oțelea, Marina Ruxandra / Zugravu, Corina / Rașcu, Agripina / Arghir, Oana Cristina / Manolescu, Loredana Sabina Cornelia / Mates, Dana

    Healthcare (Basel, Switzerland)

    2022  Volume 10, Issue 7

    Abstract: Background: The aim of this analysis was to explore coronasomnia in second line workers.: Methods: Data were collected via in an online questionnaire. Patients with new onset or aggravation of insomnia were defined as cases and those without insomnia ...

    Abstract Background: The aim of this analysis was to explore coronasomnia in second line workers.
    Methods: Data were collected via in an online questionnaire. Patients with new onset or aggravation of insomnia were defined as cases and those without insomnia as controls. Differences among groups were studied by nonparametric tests; the correlation among variables was assessed using regression, followed by Bonferroni adjustment.
    Results: There were 377 responders, grouped into 129 cases and 248 controls. Younger age (Odds Ratio = 0.97,
    Conclusion: Preventive measures to reduce the occurrence of insomnia in times of social stress in nonessential occupations should focus on health vulnerable groups, persons with previous history of insomnia and who develop anxiety from media.
    Language English
    Publishing date 2022-06-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare10071194
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  6. Article ; Online: Impaired Melatonin Secretion, Oxidative Stress and Metabolic Syndrome in Night Shift Work

    Hohor, Sorina / Mandanach, Cristina / Maftei, Andreea / Zugravu, Corina Aurelia / Oțelea, Marina Ruxandra

    Antioxidants. 2023 Apr. 19, v. 12, no. 4

    2023  

    Abstract: Metabolic syndrome has been associated in many studies with working in shifts. Even if the mechanistic details are not fully understood, forced sleep deprivation and exposure to light, as happens during night shifts, or irregular schedules with late or ... ...

    Abstract Metabolic syndrome has been associated in many studies with working in shifts. Even if the mechanistic details are not fully understood, forced sleep deprivation and exposure to light, as happens during night shifts, or irregular schedules with late or very early onset of the working program, lead to a sleep–wake rhythm misalignment, metabolic dysregulation and oxidative stress. The cyclic melatonin secretion is regulated by the hypothalamic suprachiasmatic nuclei and light exposure. At a central level, melatonin promotes sleep and inhibits wake-signals. Beside this role, melatonin acts as an antioxidant and influences the functionality of the cardiovascular system and of different metabolic processes. This review presents data about the influence of night shifts on melatonin secretion and oxidative stress. Assembling data from epidemiological, experimental and clinical studies contributes to a better understanding of the pathological links between chronodisruption and the metabolic syndrome related to working in shifts.
    Keywords antioxidants ; cardiovascular system ; melatonin ; metabolic syndrome ; oxidative stress ; secretion ; sleep deprivation ; work schedules
    Language English
    Dates of publication 2023-0419
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article ; Online
    ZDB-ID 2704216-9
    ISSN 2076-3921
    ISSN 2076-3921
    DOI 10.3390/antiox12040959
    Database NAL-Catalogue (AGRICOLA)

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  7. Article: Antioxidants in Hops: Bioavailability, Health Effects and Perspectives for New Products.

    Zugravu, Corina-Aurelia / Bohiltea, Roxana-Elena / Salmen, Teodor / Pogurschi, Elena / Otelea, Marina Ruxandra

    Antioxidants (Basel, Switzerland)

    2022  Volume 11, Issue 2

    Abstract: Hop plant ( ...

    Abstract Hop plant (
    Language English
    Publishing date 2022-01-27
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2704216-9
    ISSN 2076-3921
    ISSN 2076-3921
    DOI 10.3390/antiox11020241
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Club Cells-A Guardian against Occupational Hazards.

    Otelea, Marina Ruxandra / Oancea, Corina / Reisz, Daniela / Vaida, Monica Adriana / Maftei, Andreea / Popescu, Florina Georgeta

    Biomedicines

    2023  Volume 12, Issue 1

    Abstract: Club cells have a distinct role in the epithelial repair and defense mechanisms of the lung. After exposure to environmental pollutants, during chronic exposure, the secretion of club cells secretory protein (CCSP) decreases. Exposure to occupational ... ...

    Abstract Club cells have a distinct role in the epithelial repair and defense mechanisms of the lung. After exposure to environmental pollutants, during chronic exposure, the secretion of club cells secretory protein (CCSP) decreases. Exposure to occupational hazards certainly has a role in a large number of interstitial lung diseases. According to the American Thoracic Society and the European Respiratory Society, around 40% of the all interstitial lung disease is attributed to occupational hazards. Some of them are very well characterized (pneumoconiosis, hypersensitivity pneumonitis), whereas others are consequences of acute exposure (e.g., paraquat) or persistent exposure (e.g., isocyanate). The category of vapors, gases, dusts, and fumes (VGDF) has been proven to produce subclinical modifications. The inflammation and altered repair process resulting from the exposure to occupational respiratory hazards create vicious loops of cooperation between epithelial cells, mesenchymal cells, innate defense mechanisms, and immune cells. The secretions of club cells modulate the communication between macrophages, epithelial cells, and fibroblasts mitigating the inflammation and/or reducing the fibrotic process. In this review, we describe the mechanisms by which club cells contribute to the development of interstitial lung diseases and the potential role for club cells as biomarkers for occupational-related fibrosis.
    Language English
    Publishing date 2023-12-28
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines12010078
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Dark Chocolate: To Eat or Not to Eat? A Review.

    Zugravu, Corina / Otelea, Marina Ruxandra

    Journal of AOAC International

    2019  Volume 102, Issue 5, Page(s) 1388–1396

    Abstract: Dark chocolate is not the most popular chocolate; the higher concentration in antioxidants pays tribute to the increment in bitterness. The caloric density of dark chocolate is potentially lower but has a large variability according to recipes and ... ...

    Abstract Dark chocolate is not the most popular chocolate; the higher concentration in antioxidants pays tribute to the increment in bitterness. The caloric density of dark chocolate is potentially lower but has a large variability according to recipes and ingredients. Nevertheless, in the last decade, the interest in dark chocolate as a potential functional food has constantly increased. In this review, we present the nutritional composition, factors influencing the bioavailability, and health outcomes of dark chocolate intake. We have extracted pro- and counter-arguments to illustrate these effects from both experimental and clinical studies in an attempt to solve the dilemma. The antioxidative and anti-inflammatory abilities, the cardiovascular and metabolic effects, and influences on central neural functions were selected to substantiate the main positive consequences. Beside the caloric density, we have included reports placing responsibility on chocolate as a migraine trigger or as an inducer of the gastroesophagial reflux in the negative effects section. Despite an extensive literature review, there are not large enough studies specifically dedicated to dark chocolate that took into consideration possible confounders on the health-related effects. Therefore, a definite answer on our initial question is, currently, not available.
    MeSH term(s) Animals ; Cacao/chemistry ; Chocolate/adverse effects ; Functional Food/adverse effects ; Humans ; Polyphenols/pharmacology
    Chemical Substances Polyphenols
    Language English
    Publishing date 2019-06-14
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1103149-9
    ISSN 1944-7922 ; 1060-3271
    ISSN (online) 1944-7922
    ISSN 1060-3271
    DOI 10.5740/jaoacint.19-0132
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1229: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  10. Article ; Online: The Pathological Links between Adiposity and the Carpal Tunnel Syndrome.

    Otelea, Marina Ruxandra / Nartea, Roxana / Popescu, Florina Georgeta / Covaleov, Anatoli / Mitoiu, Brindusa Ilinca / Nica, Adriana Sarah

    Current issues in molecular biology

    2022  Volume 44, Issue 6, Page(s) 2646–2663

    Abstract: An association between obesity and carpal tunnel syndrome is found in many epidemiological studies. Therefore, there is a need to evaluate the physiopathological links that could explain the association between these two entities. Ectopic adipose tissue ... ...

    Abstract An association between obesity and carpal tunnel syndrome is found in many epidemiological studies. Therefore, there is a need to evaluate the physiopathological links that could explain the association between these two entities. Ectopic adipose tissue is responsible for metabolic syndrome and inflammation, and is a major risk factor for diabetes and cardiovascular diseases. Taking these elements into consideration, we conducted an extensive literature revision of the subject, considering as ectopic fat-related mechanisms the following: (a) the direct compression and the association with the metabolic syndrome of the fat deposition around the wrist, (b) the insulin resistance, dyslipidemia, inflammatory, and oxidative mechanisms related to the central deposition of the fat, (c) the impaired muscle contraction and metabolism related to myosteatosis. Each section presents the cellular pathways which are modified by the ectopic deposition of the adipose tissue and the impact in the pathogeny of the carpal tunnel syndrome. In conclusion, the experimental and clinical data support the epidemiological findings. Efforts to reduce the obesity epidemics will improve not only cardio-metabolic health but will reduce the burden of the disability-free life expectancy due to the carpal tunnel syndrome.
    Language English
    Publishing date 2022-06-08
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2000024-8
    ISSN 1467-3045 ; 1467-3037
    ISSN (online) 1467-3045
    ISSN 1467-3037
    DOI 10.3390/cimb44060181
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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