Article ; Online: Vaccination of Pregnant Women Against COVID-19.
NeoReviews
2021 Volume 22, Issue 9, Page(s) e570–e573
Abstract: Pregnant women are at increased risk for severe morbidity and mortality following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), leading some countries to recommend vaccination of pregnant women against coronavirus disease ... ...
| Abstract | Pregnant women are at increased risk for severe morbidity and mortality following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), leading some countries to recommend vaccination of pregnant women against coronavirus disease 2019 (COVID-19). These recommendations are based on studies conducted early in the pandemic, and thus, the pregnant women in these studies most likely did not have pre-existing immunity to SARS-CoV-2 at the time of infection. The susceptibility of pregnant women and their infants to SARS-CoV-2 and the severity of infection may be attenuated as the pandemic progresses and an increasing number of women will have pre-existing immunity (following natural infection or vaccination prior to pregnancy) during pregnancy. The reactogenicity, immunogenicity and efficacy of COVID-19 vaccines administered in pregnancy may also be affected by the pre-existing immunity of pregnant women. Maternal vaccine trials should be evaluated in the context of their timing in the pandemic and interpreted based on the pre-existing immunity of pregnant women. |
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| MeSH term(s) | COVID-19/immunology ; COVID-19/mortality ; COVID-19/prevention & control ; COVID-19/virology ; COVID-19 Vaccines/administration & dosage ; COVID-19 Vaccines/adverse effects ; COVID-19 Vaccines/immunology ; Female ; Humans ; Pregnancy ; Pregnancy Complications, Infectious/immunology ; Pregnancy Complications, Infectious/mortality ; Pregnancy Complications, Infectious/prevention & control ; Pregnancy Complications, Infectious/virology ; Pregnant Women ; SARS-CoV-2/immunology ; Vaccination |
| Chemical Substances | COVID-19 Vaccines |
| Language | English |
| Publishing date | 2021-09-08 |
| Publishing country | United States |
| Document type | Journal Article |
| ISSN | 1526-9906 |
| ISSN (online) | 1526-9906 |
| DOI | 10.1542/neo.22-9-e570 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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