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Article: Protozoan Parasites of Rodents and Their Zoonotic Significance in Boyer-Ahmad District, Southwestern Iran.

Seifollahi, Zeinab / Sarkari, Bahador / Motazedian, Mohammad Hossein / Asgari, Qasem / Ranjbar, Mohammad Javad / Abdolahi Khabisi, Samaneh

Veterinary medicine international

2016 Volume 2016, Page(s) 3263868

Abstract: ... Ahmad district, southwestern Iran. Materials and Methods. A total of 52 rodents were collected ... from different parts of Boyer-Ahmad district, in Kohgiluyeh and Boyer-Ahmad province, using Sherman live traps ... in Kohgiluyeh and Boyer-Ahmad province, southwestern Iran, are infected with several blood and intestinal ...

Abstract	Backgrounds. Wild rodents are reservoirs of various zoonotic diseases, such as toxoplasmosis, babesiosis, and leishmaniasis. The current study aimed to assess the protozoan infection of rodents in Boyer-Ahmad district, southwestern Iran. Materials and Methods. A total of 52 rodents were collected from different parts of Boyer-Ahmad district, in Kohgiluyeh and Boyer-Ahmad province, using Sherman live traps. Each rodent was anesthetized with ether, according to the ethics of working with animals, and was dissected. Samples were taken from various tissues and stool samples were collected from the contents of the colon and small intestines. Moreover, 2 to 5 mL of blood was taken from each of the rodents and the sera were examined for anti-Leishmania antibodies, by ELISA, or anti-T. gondii antibodies, by modified agglutination test (MAT). DNA was extracted from brain tissue samples of each rodent and PCR was used to identify the DNA of T. gondii. Results. Of the 52 stool samples of rodents studied by parasitological methods, intestinal protozoa infection was seen in 28 cases (53.8%). From 52 rodents, 19 (36.5%) were infected with Trichomonas, 10 (19.2%) with Giardia muris, and 11 (21.2%) with Entamoeba spp. Also, 10 cases (19.2%) were infected with Blastocystis, 3 (5.8%) were infected with Chilomastix, 7 (13.5%) were infected with Endolimax, 1 (1.9%) was infected with Retortamonas, 3 (5.77%) were infected with T. gondii, and 6 (11.54%) were infected with Trypanosoma lewisi. Antibodies to T. gondii were detected in the sera of 5 (9.61%) cases. Results of the molecular study showed T. gondii infection in 3 (5.77%) of the rodents. Findings of this study showed that rodents in Kohgiluyeh and Boyer-Ahmad province, southwestern Iran, are infected with several blood and intestinal parasites; some of them might be potential risks to residents and domestic animals in the region.
Language	English
Publishing date	2016-02-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	2536385-2
ISSN	2042-0048 ; 2090-8113
ISSN (online)	2042-0048
ISSN	2090-8113
DOI	10.1155/2016/3263868
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Protozoan Parasites of Rodents and Their Zoonotic Significance in Boyer-Ahmad District, Southwestern Iran

Zeinab Seifollahi / Bahador Sarkari / Mohammad Hossein Motazedian / Qasem Asgari / Mohammad Javad Ranjbar / Samaneh Abdolahi Khabisi

Veterinary Medicine International, Vol

2016 Volume 2016

Abstract	Backgrounds. Wild rodents are reservoirs of various zoonotic diseases, such as toxoplasmosis, babesiosis, and leishmaniasis. The current study aimed to assess the protozoan infection of rodents in Boyer-Ahmad district, southwestern Iran. Materials and Methods. A total of 52 rodents were collected from different parts of Boyer-Ahmad district, in Kohgiluyeh and Boyer-Ahmad province, using Sherman live traps. Each rodent was anesthetized with ether, according to the ethics of working with animals, and was dissected. Samples were taken from various tissues and stool samples were collected from the contents of the colon and small intestines. Moreover, 2 to 5 mL of blood was taken from each of the rodents and the sera were examined for anti-Leishmania antibodies, by ELISA, or anti-T. gondii antibodies, by modified agglutination test (MAT). DNA was extracted from brain tissue samples of each rodent and PCR was used to identify the DNA of T. gondii. Results. Of the 52 stool samples of rodents studied by parasitological methods, intestinal protozoa infection was seen in 28 cases (53.8%). From 52 rodents, 19 (36.5%) were infected with Trichomonas, 10 (19.2%) with Giardia muris, and 11 (21.2%) with Entamoeba spp. Also, 10 cases (19.2%) were infected with Blastocystis, 3 (5.8%) were infected with Chilomastix, 7 (13.5%) were infected with Endolimax, 1 (1.9%) was infected with Retortamonas, 3 (5.77%) were infected with T. gondii, and 6 (11.54%) were infected with Trypanosoma lewisi. Antibodies to T. gondii were detected in the sera of 5 (9.61%) cases. Results of the molecular study showed T. gondii infection in 3 (5.77%) of the rodents. Findings of this study showed that rodents in Kohgiluyeh and Boyer-Ahmad province, southwestern Iran, are infected with several blood and intestinal parasites; some of them might be potential risks to residents and domestic animals in the region.
Keywords	Veterinary medicine ; SF600-1100
Subject code	630
Language	English
Publishing date	2016-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Book ; Thesis: Untersuchung zur Übertragbarkeit ex-vivo bestimmter Grenzen der Präzision computerrassisterter navigierter Detektion in den OP-Saal bei Fremdkörperentfernungen im Bereich der Mund-, Kiefer- und Gesichtschirurgie

Qasem, Ahmad

eine retrospektive Untersuchung der Klinik für Mund-, Kiefer und Gesichtschirurgie über die Jahre 2010-2015

2017

Institution	Universität Duisburg-Essen
Author's details	vorgelegt von Ahmad Qasem
Language	German
Size	86 Blätter, Illustrationen
Publishing place	Duisburg ; Essen
Publishing country	Germany
Document type	Book ; Thesis
Thesis / German Habilitation thesis	Dissertation, Universität Duisburg-Essen, 2018
HBZ-ID	HT019714292
Database	Catalogue ZB MED Medicine, Health

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2018 E 946	order for loan	Magazin

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Article: AMS-U-Net: automatic mass segmentation in digital breast tomosynthesis via U-Net.

Qasem, Ahmad / Qin, Genggeng / Zhou, Zhiguo

Journal of medical imaging (Bellingham, Wash.)

2024 Volume 11, Issue 2, Page(s) 24005

Abstract: Purpose: The objective of this study was to develop a fully automatic mass segmentation method called AMS-U-Net for digital breast tomosynthesis (DBT), a popular breast cancer screening imaging modality. The aim was to address the challenges posed by ... ...

Abstract	Purpose: The objective of this study was to develop a fully automatic mass segmentation method called AMS-U-Net for digital breast tomosynthesis (DBT), a popular breast cancer screening imaging modality. The aim was to address the challenges posed by the increasing number of slices in DBT, which leads to higher mass contouring workload and decreased treatment efficiency. Approach: The study used 50 slices from different DBT volumes for evaluation. The AMS-U-Net approach consisted of four stages: image pre-processing, AMS-U-Net training, image segmentation, and post-processing. The model performance was evaluated by calculating the true positive ratio (TPR), false positive ratio (FPR), F-score, intersection over union (IoU), and 95% Hausdorff distance (pixels) as they are appropriate for datasets with class imbalance. Results: The model achieved 0.911, 0.003, 0.911, 0.900, 5.82 for TPR, FPR, F-score, IoU, and 95% Hausdorff distance, respectively. Conclusions: The AMS-U-Net model demonstrated impressive visual and quantitative results, achieving high accuracy in mass segmentation without the need for human interaction. This capability has the potential to significantly increase clinical efficiency and workflow in DBT for breast cancer screening.
Language	English
Publishing date	2024-03-23
Publishing country	United States
Document type	Journal Article
ISSN	2329-4302
ISSN	2329-4302
DOI	10.1117/1.JMI.11.2.024005
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Article ; Online: Folate and Vitamin B

Vaccaro, Joseph A / Qasem, Ahmad / Naser, Saleh A

Nutrients

2023 Volume 15, Issue 2

Abstract: Folate and vitamin ... ...

Abstract	Folate and vitamin B
MeSH term(s)	Humans ; Caco-2 Cells ; Crohn Disease/complications ; Crohn Disease/microbiology ; Cytokines ; Folic Acid ; Inflammation ; Mycobacterium avium subsp. paratuberculosis ; Paratuberculosis/complications ; Tumor Necrosis Factor-alpha ; Vitamin B 12 ; Vitamins ; Vitamin B 12 Deficiency/complications ; Folic Acid Deficiency/complications
Chemical Substances	Cytokines ; Folic Acid (935E97BOY8) ; Tumor Necrosis Factor-alpha ; Vitamin B 12 (P6YC3EG204) ; Vitamins
Language	English
Publishing date	2023-01-04
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu15020261
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Article ; Online: Cardiac arrhythmias classification using photoplethysmography database.

Qananwah, Qasem / Ababneh, Marwa / Dagamseh, Ahmad

Scientific reports

2024 Volume 14, Issue 1, Page(s) 3355

Abstract: Worldwide, Cardiovascular Diseases (CVDs) are the leading cause of death. Patients at high cardiovascular risk require long-term follow-up for early CVDs detection. Generally, cardiac arrhythmia detection through the electrocardiogram (ECG) signal has ... ...

Abstract	Worldwide, Cardiovascular Diseases (CVDs) are the leading cause of death. Patients at high cardiovascular risk require long-term follow-up for early CVDs detection. Generally, cardiac arrhythmia detection through the electrocardiogram (ECG) signal has been the basis of many studies. This technique does not provide sufficient information in addition to a high false alarm potential. In addition, the electrodes used to record the ECG signal are not suitable for long-term monitoring. Recently, the photoplethysmogram (PPG) signal has attracted great interest among scientists as it provides a non-invasive, inexpensive, and convenient source of information related to cardiac activity. In this paper, the PPG signal (online database Physio Net Challenge 2015) is used to classify different cardiac arrhythmias, namely, tachycardia, bradycardia, ventricular tachycardia, and ventricular flutter/fibrillation. The PPG signals are pre-processed and analyzed utilizing various signal-processing techniques to eliminate noise and artifacts, which forms a stage of signal preparation prior to the feature extraction process. A set of 41 PPG features is used for cardiac arrhythmias' classification through the application of four machine-learning techniques, namely, Decision Trees (DT), Support Vector Machines (SVM), K-Nearest Neighbors (KNNs), and Ensembles. Principal Component Analysis (PCA) technique is used for dimensionality reduction and feature extraction while preserving the most important information in the data. The results show a high-throughput evaluation with an accuracy of 98.4% for the KNN technique with a sensitivity of 98.3%, 95%, 96.8%, and 99.7% for bradycardia, tachycardia, ventricular flutter/fibrillation, and ventricular tachycardia, respectively. The outcomes of this work provide a tool to correlate the properties of the PPG signal with cardiac arrhythmias and thus the early diagnosis and treatment of CVDs.
MeSH term(s)	Humans ; Photoplethysmography ; Bradycardia ; Arrhythmias, Cardiac/diagnosis ; Signal Processing, Computer-Assisted ; Electrocardiography ; Tachycardia, Ventricular/diagnosis ; Algorithms
Language	English
Publishing date	2024-02-09
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-53142-9
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Article ; Online: Investigating the impact of smoking habits through photoplethysmography analysis.

Qananwah, Qasem / Khader, Ateka / Al-Hashem, Munder / Mumani, Ahmad / Dagamseh, Ahmad

Physiological measurement

2024 Volume 45, Issue 1

Abstract: Smoking is widely recognized as a significant risk factor in the progression of arterial stiffness and cardiovascular diseases. Valuable information related to cardiac arrhythmias and heart function can be obtained by analyzing biosignals such as the ... ...

Abstract	Smoking is widely recognized as a significant risk factor in the progression of arterial stiffness and cardiovascular diseases. Valuable information related to cardiac arrhythmias and heart function can be obtained by analyzing biosignals such as the electrocardiogram (ECG) and the photoplethysmogram (PPG). The PPG signal is a non-invasive optical technique that can be used to evaluate the changes in blood volume, and thus it can be linked to the health of the vascular system.
MeSH term(s)	Humans ; Photoplethysmography/methods ; Electronic Nicotine Delivery Systems ; Cardiovascular Diseases ; Smoking/adverse effects ; Heart Rate ; Signal Processing, Computer-Assisted
Language	English
Publishing date	2024-01-22
Publishing country	England
Document type	Journal Article
ZDB-ID	1149545-5
ISSN	1361-6579 ; 0967-3334
ISSN (online)	1361-6579
ISSN	0967-3334
DOI	10.1088/1361-6579/ad1b10
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Article ; Online: Comparison of effects of peripheral vasculature on tonometric radial pulse and cuff-based brachial pulse waveform as used in estimation of central aortic pressures.

Butlin, Mark / Tan, Isabella / Qasem, Ahmad / Avolio, Alberto P

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

2023 Volume 2023, Page(s) 1–4

Abstract: Objective: Aortic pressure estimation requires reliable peripheral pulse waveform acquisition. The peripheral waveform can change with local vascular effects that can be independent of aortic pressure. This study quantifies the effects of peripheral ... ...

Abstract	Objective: Aortic pressure estimation requires reliable peripheral pulse waveform acquisition. The peripheral waveform can change with local vascular effects that can be independent of aortic pressure. This study quantifies the effects of peripheral vasculature changes on radial and brachial waveforms. Design and method: In 20 subjects (37± 15 years, 7 female), brachial volumetric displacement (cuff-based) and radial tonometry waveforms were simultaneously measured whilst a cuff around the hand on the same arm was inflated to induce transmural pressures of -60, -30, -15, 0, 15 and 30 mmHg, altering local peripheral resistance and compliance by graded arterial wall unloading. Aortic blood pressure (BP), augmentation index (AIx) and ejection duration were calculated from the measurements using a generalized transfer function. The parameters under unloaded conditions were compared to baseline measurements. Results: Brachial systolic and diastolic BP did not change throughout the experiment. Altering peripheral resistance and compliance did not significantly change calculated aortic BP values, although changes were nominally greater for radial (maximum +8±1 mmHg) compared to brachial (maximum +2±1 mmHg) waveforms. AIx at 0 mmHg transmural pressure (maximum arterial wall unloading) was higher when derived from radial waveforms (+24±3%, p<0.001) but not when derived from brachial waveforms. Conclusions: Localized changes in peripheral resistance and compliance affect tonometer acquired radial waveforms but not volumetric displacement acquired brachial pressure waveforms, as judged by computed central aortic augmentation pressure parameters. This suggests aortic pressure estimation from the brachial cuff waveform is less sensitive to peripheral vasculature disturbances that alter the peripheral arterial pulse morphology.
MeSH term(s)	Humans ; Female ; Arterial Pressure ; Blood Pressure Determination ; Brachial Artery/physiology ; Blood Pressure/physiology ; Manometry
Language	English
Publishing date	2023-12-11
Publishing country	United States
Document type	Journal Article
ISSN	2694-0604
ISSN (online)	2694-0604
DOI	10.1109/EMBC40787.2023.10340973
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Article ; Online: Cathelicidin Mediates an Anti-Inflammatory Role of Active Vitamin D (Calcitriol) During

Vaccaro, Joseph A / Qasem, Ahmad / Naser, Saleh A

Frontiers in cellular and infection microbiology

2022 Volume 12, Page(s) 875772

Abstract: Vitamin D is a key regulator in calcium and phosphorus metabolism which are essential for maintaining bone health. Recent reports also showed a role for vitamin D in immune regulation which may be linked to vitamin D deficiency in autoimmune disorders ... ...

Abstract	Vitamin D is a key regulator in calcium and phosphorus metabolism which are essential for maintaining bone health. Recent reports also showed a role for vitamin D in immune regulation which may be linked to vitamin D deficiency in autoimmune disorders including inflammatory diseases and Crohn's disease (CD). This study examines the role of vitamin D deficiency in the regulation of Cathelicidin Antimicrobial Peptide (
MeSH term(s)	Animals ; Anti-Inflammatory Agents/pharmacology ; Antimicrobial Cationic Peptides ; Caco-2 Cells ; Calcifediol ; Calcitriol/pharmacology ; Humans ; Mycobacterium avium subsp. paratuberculosis ; Paratuberculosis/microbiology ; Tumor Necrosis Factor-alpha ; Vitamin D/pharmacology ; Vitamin D Deficiency/complications
Chemical Substances	Anti-Inflammatory Agents ; Antimicrobial Cationic Peptides ; Tumor Necrosis Factor-alpha ; Vitamin D (1406-16-2) ; ropocamptide (3DD771JO2H) ; Calcitriol (FXC9231JVH) ; Calcifediol (P6YZ13C99Q)
Language	English
Publishing date	2022-04-04
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2619676-1
ISSN	2235-2988 ; 2235-2988
ISSN (online)	2235-2988
ISSN	2235-2988
DOI	10.3389/fcimb.2022.875772
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Article ; Online: Attenuation of Excess TNF-α Release in Crohn's Disease by Silencing of iRHOMs 1/2 and the Restoration of TGF-β Mediated Immunosuppression Through Modulation of TACE Trafficking.

Louis, Taylor J / Qasem, Ahmad / Naser, Saleh A

Frontiers in immunology

2022 Volume 13, Page(s) 887830

Abstract: TNFα converting enzyme (TACE) is a transmembrane metalloprotease that sheds an assortment of signaling receptors, cytokines, growth factors, and pro-inflammatory mediators. In Crohn's disease (CD), TACE activity is upregulated, resulting in a marked ... ...

Abstract	TNFα converting enzyme (TACE) is a transmembrane metalloprotease that sheds an assortment of signaling receptors, cytokines, growth factors, and pro-inflammatory mediators. In Crohn's disease (CD), TACE activity is upregulated, resulting in a marked increase of TNFα secretion and inflammation. Although treatment of CD with TNFα monoclonal antibodies is beneficial, many patients are at risk for acquiring opportunistic infections, and the treatment efficacy of TNFα monoclonal antibodies typically decreases over time. This study investigated an alternative approach for mitigating TNFα release by knocking down TACE membrane translocation in macrophages
MeSH term(s)	Animals ; Antibodies, Monoclonal ; Crohn Disease/metabolism ; Cytokines ; Gene Silencing ; Humans ; Immunosuppression Therapy ; Intracellular Signaling Peptides and Proteins/genetics ; Ligands ; Membrane Proteins/genetics ; Mycobacterium avium subsp. paratuberculosis ; RNA, Small Interfering ; Transforming Growth Factor beta/immunology ; Tumor Necrosis Factor-alpha/metabolism
Chemical Substances	Antibodies, Monoclonal ; Cytokines ; Intracellular Signaling Peptides and Proteins ; Ligands ; Membrane Proteins ; RHBDF2 protein, human ; RNA, Small Interfering ; Transforming Growth Factor beta ; Tumor Necrosis Factor-alpha
Language	English
Publishing date	2022-05-02
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2606827-8
ISSN	1664-3224 ; 1664-3224
ISSN (online)	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2022.887830
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