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  1. Article ; Online: Co-distribution of Light At Night (LAN) and COVID-19 incidence in the United States.

    Meng, Yidan / Zhu, Vincent / Zhu, Yong

    BMC public health

    2021  Volume 21, Issue 1, Page(s) 1509

    Abstract: Background: Light at night (LAN) as a circadian disruption factor may affect the human ... analysis aimed to test whether there is an association between LAN and COVID-19 cases in 4 selected ... of COVID-19 cases in ArcMap and performed a multiple linear regression model using data of LAN and COVID-19 ...

    Abstract Background: Light at night (LAN) as a circadian disruption factor may affect the human immune system and consequently increase an individual's susceptibility to the severity of infectious diseases, such as COVID-19. COVID-19 infections spread differently in each state in the United States (US). The current analysis aimed to test whether there is an association between LAN and COVID-19 cases in 4 selected US states: Connecticut, New York, California, and Texas.
    Methods: We analyzed clustering patterns of COVID-19 cases in ArcMap and performed a multiple linear regression model using data of LAN and COVID-19 incidence with adjustment for confounding variables including population density, percent below poverty, and racial factors.
    Results: Hotspots of LAN and COVID-19 cases are located in large cities or metro-centers for all 4 states. LAN intensity is associated with cases/1 k for overall and lockdown durations in New York and Connecticut (P < 0.001), but not in Texas and California. The overall case rates are significantly associated with LAN in New York (P < 0.001) and Connecticut (P < 0.001).
    Conclusions: We observed a significant positive correlation between LAN intensity and COVID-19 cases-rate/1 k, suggesting that circadian disruption of ambient light may increase the COVID-19 infection rate possibly by affecting an individual's immune functions. Furthermore, differences in the demographic structure and lockdown policies in different states play an important role in COVID-19 infections.
    MeSH term(s) COVID-19 ; Circadian Rhythm ; Communicable Disease Control ; Connecticut/epidemiology ; Humans ; Incidence ; SARS-CoV-2 ; United States/epidemiology
    Language English
    Publishing date 2021-08-04
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1471-2458
    ISSN (online) 1471-2458
    DOI 10.1186/s12889-021-11500-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Anti-microtubule activity of the traditional Chinese medicine herb Northern Ban Lan (Isatis tinctoria) leads to glucobrassicin.

    Guan, Pingyin / Zhou, Jianning / Girel, Sergey / Zhu, Xin / Schwab, Marian / Zhang, Kunxi / Wang-Müller, Qiyan / Bigler, Laurent / Nick, Peter

    Journal of integrative plant biology

    2021  Volume 63, Issue 12, Page(s) 2058–2074

    Abstract: ... based healing. The herb Northern Ban Lan (Isatis tinctoria) is famous for its antiviral and ...

    Abstract Traditional Chinese medicine (TCM) belongs to the most elaborate and extensive systems of plant-based healing. The herb Northern Ban Lan (Isatis tinctoria) is famous for its antiviral and anti-inflammatory activity. Although numerous components isolated from I. tinctoria have been characterized so far, their modes of action have remained unclear. Here, we show that extracts from I. tinctoria exert anti-microtubular activity. Using time-lapse microscopy in living tobacco BY-2 (Nicotiana tabacum L. cv Bright Yellow 2) cells expressing green fluorescent protein-tubulin, we use activity-guided fractionation to screen out the biologically active compounds of I. tinctoria. Among 54 fractions obtained from either leaves or roots of I. tinctoria by methanol (MeOH/H
    MeSH term(s) Glucosinolates ; HeLa Cells ; Humans ; Indoles ; Isatis/chemistry ; Medicine, Chinese Traditional ; Microtubules
    Chemical Substances Glucosinolates ; Indoles ; glucobrassicin (EA6EH0IU89)
    Language English
    Publishing date 2021-11-10
    Publishing country China (Republic : 1949- )
    Document type Journal Article
    ZDB-ID 2130095-1
    ISSN 1744-7909 ; 1672-9072
    ISSN (online) 1744-7909
    ISSN 1672-9072
    DOI 10.1111/jipb.13177
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Functional mapping of tillering QTLs using the Wang-Lan-Ding model and a SSSL population.

    Luan, Xin / Xiong, Liang / Xu, Haiming / Zhu, Haitao / Bu, Suhong / Meng, Lijun / Liu, Guifu / Wang, Shaokui

    Molecular genetics and genomics : MGG

    2021  Volume 296, Issue 6, Page(s) 1279–1286

    Abstract: ... agronomic traits in plants. Based on the Wang-Lan-Ding model, we ever applied a DH population to carry out ... mapping was again conducted on tiller number using the Wang-Lan-Ding model and a single segment ...

    Abstract Understanding dynamic changes in the genetic architecture of quantitative traits is crucial in developmental genetics. Functional mapping is an appropriate method that passes a mathematical equation to describe a biological developmental process with the genetic mapping framework. Appropriate genetic model and applicable mapping population are indispensable condition for functional mapping of important agronomic traits in plants. Based on the Wang-Lan-Ding model, we ever applied a DH population to carry out functional mapping QTLs underlying growth trajectory on tiller number. However, inconsistent genetic background among the DH lines might disturb the mapping results. With the advent of innovative research materials, single segment substitution lines, allows us to do more precise genetic analyses. Thus functional mapping was again conducted on tiller number using the Wang-Lan-Ding model and a single segment substitution line population with the genetic background of Huajingxian 74 so as to explore QTL dynamic mechanism to regulate developmental traits. We detected that all five single segment substitution lines harbored tillering QTLs with additives and/or dominances to influence the four functional parameters, the optimum tillering time (t
    MeSH term(s) Chromosome Mapping/methods ; Chromosomes, Plant/genetics ; Epistasis, Genetic/genetics ; Models, Theoretical ; Oryza/classification ; Oryza/genetics ; Phenotype ; Plant Breeding/methods ; Quantitative Trait Loci/genetics
    Language English
    Publishing date 2021-09-18
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2044817-X
    ISSN 1617-4623 ; 1617-4615
    ISSN (online) 1617-4623
    ISSN 1617-4615
    DOI 10.1007/s00438-021-01819-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1198: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Reply to Amit Bansal and Anant Kumar's Letter to the Editor re: Lan Zhu, Nianqiao Gong, Bin Liu, et al. Coronavirus Disease 2019 Pneumonia in Immunosuppressed Renal Transplant Recipients: A Summary of 10 Confirmed Cases in Wuhan, China. Eur Urol 2020;77:748-54.

    Zhu, Lan / Chen, Gang

    European urology

    2020  Volume 78, Issue 4, Page(s) e159–e160

    MeSH term(s) Betacoronavirus ; COVID-19 ; China ; Coronavirus ; Coronavirus Infections ; Humans ; Kidney Transplantation ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-07-04
    Publishing country Switzerland
    Document type Letter ; Comment
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2020.06.062
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1247: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 294: Show issues

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  5. Article ; Online: Co-distribution of Light At Night (LAN) and COVID-19 incidence in the United States

    Yidan Meng / Vincent Zhu / Yong Zhu

    BMC Public Health, Vol 21, Iss 1, Pp 1-

    2021  Volume 8

    Abstract: Abstract Background Light at night (LAN) as a circadian disruption factor may affect the human ... analysis aimed to test whether there is an association between LAN and COVID-19 cases in 4 selected ... cases in ArcMap and performed a multiple linear regression model using data of LAN and COVID-19 ...

    Abstract Abstract Background Light at night (LAN) as a circadian disruption factor may affect the human immune system and consequently increase an individual’s susceptibility to the severity of infectious diseases, such as COVID-19. COVID-19 infections spread differently in each state in the United States (US). The current analysis aimed to test whether there is an association between LAN and COVID-19 cases in 4 selected US states: Connecticut, New York, California, and Texas. Methods We analyzed clustering patterns of COVID-19 cases in ArcMap and performed a multiple linear regression model using data of LAN and COVID-19 incidence with adjustment for confounding variables including population density, percent below poverty, and racial factors. Results Hotspots of LAN and COVID-19 cases are located in large cities or metro-centers for all 4 states. LAN intensity is associated with cases/1 k for overall and lockdown durations in New York and Connecticut (P < 0.001), but not in Texas and California. The overall case rates are significantly associated with LAN in New York (P < 0.001) and Connecticut (P < 0.001). Conclusions We observed a significant positive correlation between LAN intensity and COVID-19 cases-rate/1 k, suggesting that circadian disruption of ambient light may increase the COVID-19 infection rate possibly by affecting an individual’s immune functions. Furthermore, differences in the demographic structure and lockdown policies in different states play an important role in COVID-19 infections.
    Keywords Light at night (LAN) ; COVID-19 ; Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2021-08-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  6. Article: Functional mapping of tillering QTLs using the Wang–Lan–Ding model and a SSSL population

    Luan, Xin / Xiong, Liang / Xu, Haiming / Zhu, Haitao / Bu, Suhong / Meng, Lijun / Liu, Guifu / Wang, Shaokui

    Molecular genetics and genomics. 2021 Nov., v. 296, no. 6

    2021  

    Abstract: ... agronomic traits in plants. Based on the Wang–Lan–Ding model, we ever applied a DH population to carry out ... mapping was again conducted on tiller number using the Wang–Lan–Ding model and a single segment ... the tillering decreased rate (c), which were estimated from the Wang–Lan–Ding model and with some biological ...

    Abstract Understanding dynamic changes in the genetic architecture of quantitative traits is crucial in developmental genetics. Functional mapping is an appropriate method that passes a mathematical equation to describe a biological developmental process with the genetic mapping framework. Appropriate genetic model and applicable mapping population are indispensable condition for functional mapping of important agronomic traits in plants. Based on the Wang–Lan–Ding model, we ever applied a DH population to carry out functional mapping QTLs underlying growth trajectory on tiller number. However, inconsistent genetic background among the DH lines might disturb the mapping results. With the advent of innovative research materials, single segment substitution lines, allows us to do more precise genetic analyses. Thus functional mapping was again conducted on tiller number using the Wang–Lan–Ding model and a single segment substitution line population with the genetic background of Huajingxian 74 so as to explore QTL dynamic mechanism to regulate developmental traits. We detected that all five single segment substitution lines harbored tillering QTLs with additives and/or dominances to influence the four functional parameters, the optimum tillering time (t₀), the maximum tiller number (K), the tillering increased rate (r) and the tillering decreased rate (c), which were estimated from the Wang–Lan–Ding model and with some biological meaning. They mainly brought the inflexion point (t₀) delay, the peak increase (K) and the degradation (c) acceleration, while the growth (r) slow down. Moreover, epistatic interactions among these QTLs were confirmed to be prevalent. A total of 39 significant epistatic effects were detected to associate with the four parameters, occupying 34.8% of 112 pairs of epistatic interactions investigated. Contrary to the QTL effects, these epistatic effects largely decreased t₀, K and c, while increased r. Our results indicated that the five QTL effects and their epistatic effects significantly changed the shape and trajectory of tiller number via influence of the four functional parameters. Rational use of these QTLs is expected to improve tillering number of rice by molecular design breeding.
    Keywords epistasis ; equations ; genetic background ; genetic models ; genomics ; rice ; substitution lines ; tillering
    Language English
    Dates of publication 2021-11
    Size p. 1279-1286.
    Publishing place Springer Berlin Heidelberg
    Document type Article
    ISSN 1617-4615
    DOI 10.1007/s00438-021-01819-5
    Database NAL-Catalogue (AGRICOLA)

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  7. Article: Anti‐microtubule activity of the traditional Chinese medicine herb Northern Ban Lan (Isatis tinctoria) leads to glucobrassicin

    Guan, Pingyin / Zhou, Jianning / Girel, Sergey / Zhu, Xin / Schwab, Marian / Zhang, Kunxi / Wang‐Müller, Qiyan / Bigler, Laurent / Nick, Peter

    Journal of integrative plant biology. 2021 Dec., v. 63, no. 12

    2021  

    Abstract: ... based healing. The herb Northern Ban Lan (Isatis tinctoria) is famous for its antiviral and anti ... the antiviral activity of Northern Ban Lan is discussed in the context of microtubules being hijacked ...

    Abstract Traditional Chinese medicine (TCM) belongs to the most elaborate and extensive systems of plant‐based healing. The herb Northern Ban Lan (Isatis tinctoria) is famous for its antiviral and anti‐inflammatory activity. Although numerous components isolated from I. tinctoria have been characterized so far, their modes of action have remained unclear. Here, we show that extracts from I. tinctoria exert anti‐microtubular activity. Using time‐lapse microscopy in living tobacco BY‐2 (Nicotiana tabacum L. cv Bright Yellow 2) cells expressing green fluorescent protein‐tubulin, we use activity‐guided fractionation to screen out the biologically active compounds of I. tinctoria. Among 54 fractions obtained from either leaves or roots of I. tinctoria by methanol (MeOH/H₂O 8:2), or ethyl acetate extraction, one specific methanolic root fraction was selected, because it efficiently and rapidly eliminated microtubules. By combination of further purification with ultra‐high‐performance liquid chromatography and high‐resolution tandem mass spectrometry most of the bioactivity could be assigned to the glucosinolate compound glucobrassicin. Glucobrassicin can also affect microtubules and induce apoptosis in HeLa cells. In the light of these findings, the antiviral activity of Northern Ban Lan is discussed in the context of microtubules being hijacked by many viral pathogens for cell‐to‐cell spread.
    Keywords Isatis tinctoria ; Nicotiana tabacum ; Oriental traditional medicine ; anti-inflammatory activity ; antiviral properties ; apoptosis ; ethyl acetate ; fluorescence ; fractionation ; glucobrassicin ; medicinal plants ; methanol ; microscopy ; microtubules ; tandem mass spectrometry ; tobacco ; ultra-performance liquid chromatography
    Language English
    Dates of publication 2021-12
    Size p. 2058-2074.
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note JOURNAL ARTICLE
    ZDB-ID 2130095-1
    ISSN 1744-7909 ; 1672-9072
    ISSN (online) 1744-7909
    ISSN 1672-9072
    DOI 10.1111/jipb.13177
    Database NAL-Catalogue (AGRICOLA)

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  8. Book: Ban lan huasheng

    Zhu, Wenshun

    1974  

    Author's details [Regie: Zhu Wenshun]
    Language Chinese
    Size 1 VCD, 42 Min
    Publishing place China
    Document type Book
    Note Audiosprache: Chinesisch
    Database Former special subject collection: coastal and deep sea fishing

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  9. Article ; Online: Effects of magnesium hydroxide morphology on Pb(ii) removal from aqueous solutions.

    Zhu, Donghai / Zhu, Jiachen / Li, Ping / Lan, Shengjie

    RSC advances

    2024  Volume 14, Issue 11, Page(s) 7329–7337

    Abstract: In this study, magnesium hydroxide (MH) particles with distinct morphologies were obtained through direct precipitation and subsequent hydrothermal treatment with various magnesium salts. The synthesized products were systematically characterized and ... ...

    Abstract In this study, magnesium hydroxide (MH) particles with distinct morphologies were obtained through direct precipitation and subsequent hydrothermal treatment with various magnesium salts. The synthesized products were systematically characterized and utilized for the removal of Pb(ii) ions from aqueous solutions. The adsorption process of Pb(ii) by two different MH structures, namely flower globular magnesium hydroxide (FGMH) and hexagonal plate magnesium hydroxide (HPMH), adhered to the Langmuir isotherm and pseudo-second-order model. FGMH exhibited higher Pb(ii) removal capacity (2612 mg g
    Language English
    Publishing date 2024-03-01
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d3ra08040d
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Morphology and Molecular Phylogeny of the Genus

    Liu, Benwen / Lan, Qiumei / Dai, Qingyu / Zhu, Huan / Liu, Guoxiang

    Plants (Basel, Switzerland)

    2024  Volume 13, Issue 5

    Abstract: ... ...

    Abstract Stigeoclonium
    Language English
    Publishing date 2024-03-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants13050748
    Database MEDical Literature Analysis and Retrieval System OnLINE

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