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  1. Article ; Online: Co-infection of COVID-19 and recurrent malaria.

    Pusparani, Angelita / Henrina, Joshua / Cahyadi, Alius

    Journal of infection in developing countries

    2021  Volume 15, Issue 5, Page(s) 625–629

    Abstract: In tropical countries, endemic diseases such as malaria can be challenging to distinguish from COVID-19 because of the similarities in presenting symptoms. Here we reported a case of a young soldier with fever and myalgia six days before admission, with ... ...

    Abstract In tropical countries, endemic diseases such as malaria can be challenging to distinguish from COVID-19 because of the similarities in presenting symptoms. Here we reported a case of a young soldier with fever and myalgia six days before admission, with non-productive cough, chills, nausea and vomiting, dizziness, and headache for two days. Previously, he had experienced four times of malaria infection. He had a history of positive non-falciparum malaria rapid diagnostic test (RDT) two days before admission. Significant findings were epigastric tenderness, splenomegaly, and severe thrombocytopenia of 36×103 cells / µL. A naso-oropharyngeal swab examination revealed a positive SARS-CoV-2 infection. Consequently, he was hospitalized for 12 days, successfully treated, and discharged without sequelae. Thus, in light of a pandemic, physicians need to raise the suspicion of concurrent COVID-19 infection with other tropical diseases, especially at-risk patients, because malaria and COVID-19 may share similar manifestations. Moreover, further ancillary testing, such as RDT, may be warranted.
    MeSH term(s) Anti-Bacterial Agents ; Antiviral Agents ; Azithromycin ; COVID-19/complications ; COVID-19/diagnosis ; COVID-19/drug therapy ; Coinfection ; Humans ; Indonesia ; Malaria/complications ; Malaria/diagnosis ; Malaria/drug therapy ; Male ; Oseltamivir ; Recurrence ; SARS-CoV-2 ; Young Adult
    Chemical Substances Anti-Bacterial Agents ; Antiviral Agents ; Oseltamivir (20O93L6F9H) ; Azithromycin (83905-01-5)
    Language English
    Publishing date 2021-05-31
    Publishing country Italy
    Document type Case Reports ; Journal Article
    ZDB-ID 2394024-4
    ISSN 1972-2680 ; 2036-6590
    ISSN (online) 1972-2680
    ISSN 2036-6590
    DOI 10.3855/jidc.13793
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: CrossFit-Induced Rhabdomyolysis in a Young Healthy Indonesian Male.

    Lawrensia, Sherly / Henrina, Joshua / Cahyadi, Alius

    Cureus

    2021  Volume 13, Issue 4, Page(s) e14723

    Abstract: CrossFit, a high-intensity interval training, keeps growing in trend and is one of the most favorable types of fitness, after wearable technology. However, an excessive workout is detrimental to the human body, particularly the muscle tissue. CrossFit is ...

    Abstract CrossFit, a high-intensity interval training, keeps growing in trend and is one of the most favorable types of fitness, after wearable technology. However, an excessive workout is detrimental to the human body, particularly the muscle tissue. CrossFit is known to cause exercise-induced rhabdomyolysis, a concerning disease with potentially devastating consequences. Nevertheless, only a few case reports have described this disease, and this is the first case report of such disease in Indonesia to the best of our knowledge. A 27-year-old, previously healthy and active Indonesian male presented with dark urine and myalgia in lower extremities after 720 repetitions of squats three days before admission. His urinalysis showed +1 blood, 2-7 red blood cells/high power field (HPF), but negative protein. Laboratory results showed an increase in creatine phosphokinase (CPK) (54,250 U/L) and LDH (1,670 U/L) levels, consistent with exercise-induced rhabdomyolysis, and serum calcium of 1.87 mmol/L, with normal serum creatinine and BUN level. He was hospitalized for two days and was treated with intravenous hydration therapy. CrossFit-induced rhabdomyolysis is a potentially devastating disease. Apart from prompt diagnosis and treatment, further research regarding the safe number of repetitions for CrossFit training, particularly for lower extremities are needed. Predictors of CrossFit-induced rhabdomyolysis must be sought throughout, and participants' awareness should be increased.
    Language English
    Publishing date 2021-04-27
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.14723
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: COVID-19 and misinformation: how an infodemic fuelled the prominence of vitamin D.

    Henrina, Joshua / Lim, Michael Anthonius / Pranata, Raymond

    The British journal of nutrition

    2020  Volume 125, Issue 3, Page(s) 359–360

    MeSH term(s) COVID-19 ; Communication ; Ethnic Groups ; Humans ; Incidence ; SARS-CoV-2 ; Vitamin D
    Chemical Substances Vitamin D (1406-16-2)
    Keywords covid19
    Language English
    Publishing date 2020-07-27
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 280396-3
    ISSN 1475-2662 ; 0007-1145
    ISSN (online) 1475-2662
    ISSN 0007-1145
    DOI 10.1017/S0007114520002950
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Severe Malaria in an Adult Patient from Low-Endemic Area in Flores Island, East Nusa Tenggara.

    Teressa, Maria / Purnama, Asep / Henrina, Joshua / Wiraatmadja, Agustinus / Boro, Angela M B / L Sam, Candida I / Dedang, Tersila A D / Cahyadi, Alius

    Case reports in medicine

    2023  Volume 2023, Page(s) 1239318

    Abstract: Malaria is an infection caused by protozoa of the ... ...

    Abstract Malaria is an infection caused by protozoa of the genus
    Language English
    Publishing date 2023-02-21
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2502642-2
    ISSN 1687-9635 ; 1687-9627
    ISSN (online) 1687-9635
    ISSN 1687-9627
    DOI 10.1155/2023/1239318
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Diabetes and Mortality among Patients with Chronic Kidney Disease and COVID-19: A Systematic Review, Meta-analysis, and Meta-regression.

    Iryaningrum, Maria R / Supriyadi, Rudi / Lawrensia, Sherly / Henrina, Joshua / Soetedjo, Nanny Natalia M

    Indian journal of nephrology

    2022  Volume 32, Issue 4, Page(s) 327–333

    Abstract: Introduction: Patients with kidney disease and COVID-19, whether on hemodialysis (HD) or not, have a higher risk of contracting COVID-19 accompanied by a higher mortality rate due to suppressed immune functions. Diabetes, one of the ubiquitous etiology ... ...

    Abstract Introduction: Patients with kidney disease and COVID-19, whether on hemodialysis (HD) or not, have a higher risk of contracting COVID-19 accompanied by a higher mortality rate due to suppressed immune functions. Diabetes, one of the ubiquitous etiology of kidney disease, is also associated with a composite of poor outcomes.
    Methods: Meta-analysis and meta-regression of 13 articles on COVID-19 patients with chronic kidney disease, with information on diabetes and mortality were performed using Review Manager 5.4 and OpenMetaAnalyst.
    Results: The meta-analysis of a pooled subject of 18,822 patients showed that the presence of diabetes in CKD patients with COVID-19 was associated with an increased risk of mortality (RR 1.41 (1.15, 1.72);
    Conclusions: Diabetes was associated with higher mortality risk among CKD patients, primarily those who did not need RRT.
    Language English
    Publishing date 2022-05-20
    Publishing country India
    Document type Journal Article
    ZDB-ID 2134388-3
    ISSN 1998-3662 ; 0971-4065
    ISSN (online) 1998-3662
    ISSN 0971-4065
    DOI 10.4103/ijn.ijn_293_21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Chronic Heart Failure: Clinical Implications of Iron Homeostasis Disturbances Revisited.

    Suciadi, Leonardo P / Henrina, Joshua / Putra, Iwan Cahyo Santosa / Cahyadi, Irvan / Gunawan, Hoo Felicia Hadi

    Cureus

    2022  Volume 14, Issue 1, Page(s) e21224

    Abstract: Iron deficiency is prevalent in chronic heart failure (CHF) patients. Nonetheless, the diagnosis is often overlooked and, often, the treatment is commenced just when overt anemia has ensued. Therefore, a better appreciation of this disease is needed, and ...

    Abstract Iron deficiency is prevalent in chronic heart failure (CHF) patients. Nonetheless, the diagnosis is often overlooked and, often, the treatment is commenced just when overt anemia has ensued. Therefore, a better appreciation of this disease is needed, and all seasoned cardiologists should know how to approach CHF patients with iron deficiency correctly, as mandated by clinical practice guidelines. In this comprehensive review, we describe iron homeostasis, the pathophysiologic changes of iron homeostasis, and the clinical implications of iron deficiency on CHF patients. In addition, we delineate the evolution of clinical trials, ranging from the inception to the ongoing clinical trials of iron deficiency treatment in CHF patients. Iron deficiency contributes to the worse clinical outcome of the patients. Numerous studies have reported the clinical benefit of iron supplementation, particularly in intravenous preparation, in heart failure patients regarding symptoms, functional capacity, and quality of life (QoL) improvement. Therefore, the current guidelines recommend routine screening of iron status in all newly diagnosed heart failure patients. Eventually, intravenous iron replacement is recommended for symptomatic heart failure patients with iron deficiency, irrespective of anemia.
    Language English
    Publishing date 2022-01-13
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.21224
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Machine learning-based COVID-19 acute respiratory distress syndrome phenotyping and clinical outcomes: A systematic review.

    Tenda, Eric Daniel / Henrina, Joshua / Samosir, Jistrani / Amalia, Ridha / Yulianti, Mira / Pitoyo, Ceva Wicaksono / Setiati, Siti

    Heliyon

    2023  Volume 9, Issue 6, Page(s) e17276

    Abstract: COVID-19-related acute respiratory distress syndrome (CARDS) has been suggested to differ from the typical ARDS. While distinct phenotypes of ARDS have been identified through latent class analysis (LCA), it is unclear whether such phenotypes exist for ... ...

    Abstract COVID-19-related acute respiratory distress syndrome (CARDS) has been suggested to differ from the typical ARDS. While distinct phenotypes of ARDS have been identified through latent class analysis (LCA), it is unclear whether such phenotypes exist for CARDS and how they affect clinical outcomes. To address this question, we conducted a systematic review of the current evidence.We searched several, including PubMed, EBSCO Host, and Web of Science, from inception to July 1, 2022. Our exposure and outcome of interest were different CARDS phenotypes identified and their associated outcomes, such as 28-day, 90-day, 180-day mortality, ventilator-free days, and other relevant outcomes.We identified four studies comprising a total of 1776 CARDS patients.Of the four studies, three used LCA to identify subphenotypes (SPs) of CARDS. One study based on longitudinal data identified two SPs, with SP2 associated with worse ventilation and mechanical parameters than SP1. The other two studies based on baseline data also identified two SPs, with SP2 and SP1 were associated with hyperinflammatory and hypoinflammatory CARDS, respectively. The fourth study identified three SPs primarily stratified by comorbidities using multifactorial analysis.All studies identified a subphenotype associated with poorer outcomes, including mortality, ventilator-free days, multiple-organ injury, and pulmonary embolism. Two studies reported differential responses to corticosteroids among the SPs, with improved mortality in the hyperinflammatory and worse in the hypoinflammatory SPs.Overall, our review highlights the importance of phenotyping in understanding CARDS and its impact on disease management and prognostication. However, a consensus approach to phenotyping is necessary to ensure consistency and comparability across studies. We recommend that randomized clinical trials stratified by phenotype should only be initiated after such consensus is reached.
    Short title: COVID-19 ARDS subphenotypes and outcomes.
    Language English
    Publishing date 2023-06-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e17276
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Derivation and validation of novel integrated inpatient mortality prediction score for COVID-19 (IMPACT) using clinical, laboratory, and AI-processed radiological parameter upon admission: a multicentre study.

    Tenda, Eric Daniel / Henrina, Joshua / Setiadharma, Andry / Aristy, Dahliana Jessica / Romadhon, Pradana Zaky / Thahadian, Harik Firman / Mahdi, Bagus Aulia / Adhikara, Imam Manggalya / Marfiani, Erika / Suryantoro, Satriyo Dwi / Yunus, Reyhan Eddy / Yusuf, Prasandhya Astagiri

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 2149

    Abstract: Limited studies explore the use of AI for COVID-19 prognostication. This study investigates the relationship between AI-aided radiographic parameters, clinical and laboratory data, and mortality in hospitalized COVID-19 patients. We conducted a ... ...

    Abstract Limited studies explore the use of AI for COVID-19 prognostication. This study investigates the relationship between AI-aided radiographic parameters, clinical and laboratory data, and mortality in hospitalized COVID-19 patients. We conducted a multicentre retrospective study. The derivation and validation cohort comprised of 512 and 137 confirmed COVID-19 patients, respectively. Variable selection for constructing an in-hospital mortality scoring model was performed using the least absolute shrinkage and selection operator, followed by logistic regression. The accuracy of the scoring model was assessed using the area under the receiver operating characteristic curve. The final model included eight variables: anosmia (OR: 0.280; 95%CI 0.095-0.826), dyspnoea (OR: 1.684; 95%CI 1.049-2.705), loss of consciousness (OR: 4.593; 95%CI 1.702-12.396), mean arterial pressure (OR: 0.928; 95%CI 0.900-0.957), peripheral oxygen saturation (OR: 0.981; 95%CI 0.967-0.996), neutrophil % (OR: 1.034; 95%CI 1.013-1.055), serum urea (OR: 1.018; 95%CI 1.010-1.026), affected lung area score (OR: 1.026; 95%CI 1.014-1.038). The Integrated Inpatient Mortality Prediction Score for COVID-19 (IMPACT) demonstrated a predictive value of 0.815 (95% CI 0.774-0.856) in the derivation cohort. Internal validation resulted in an AUROC of 0.770 (95% CI 0.661-0.879). Our study provides valuable evidence of the real-world application of AI in clinical settings. However, it is imperative to conduct prospective validation of our findings, preferably utilizing a control group and extending the application to broader populations.
    MeSH term(s) Humans ; COVID-19/diagnostic imaging ; Retrospective Studies ; Inpatients ; Logistic Models ; Arterial Pressure ; ROC Curve
    Language English
    Publishing date 2024-01-25
    Publishing country England
    Document type Multicenter Study ; Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-50564-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: COVID-19 and misinformation

    Henrina, Joshua / Lim, Michael Anthonius / Pranata, Raymond

    British Journal of Nutrition

    how an infodemic fuelled the prominence of vitamin D

    2020  , Page(s) 1–2

    Keywords Nutrition and Dietetics ; Medicine (miscellaneous) ; covid19
    Language English
    Publisher Cambridge University Press (CUP)
    Publishing country uk
    Document type Article ; Online
    ZDB-ID 280396-3
    ISSN 1475-2662 ; 0007-1145
    ISSN (online) 1475-2662
    ISSN 0007-1145
    DOI 10.1017/s0007114520002950
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Ue I Zs.184: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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