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Article ; Online: Surgical Technologists’ Live Experiences of Professionalization

Behzad Imani / Shima Bahrami jalal

تحقیقات کیفی در علوم سلامت, Vol 11, Iss 4, Pp 231-

A Phenomenological Study

2022 Volume 236

Abstract: Background: The rapid advancement of science and new technologies has brought wide-range changes in all professions, leading to the emergence of new concepts, including professionalism. This study aimed to explain the concept of professionalism from the ... ...

Abstract	Background: The rapid advancement of science and new technologies has brought wide-range changes in all professions, leading to the emergence of new concepts, including professionalism. This study aimed to explain the concept of professionalism from the perspective of surgical technologists. Methods: The present study was a qualitative one with conventional content analysis. A total of 11 surgical technologists were selected using purposive sampling method based on data saturation. Data were then collected using in-depth interviews. Data analysis was performed using Graneheim and Lundman’s approach. Results: In data analysis, three main themes including professional attitude, professional mastery, and holistic professional care as well as seven subthemes were extracted from the data. Conclusion: According to the findings, professionalism indicates the type of attitude of the operating room nurses towards the profession as well as the degree of their mastery in providing professional care to patients.
Keywords	professionalism ; operating room nursing ; qualitative research ; Medicine ; R ; Nursing ; RT1-120
Language	English
Publishing date	2022-12-01T00:00:00Z
Publisher	Kerman University of Medical Sciences
Document type	Article ; Online
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Article ; Online: Effects of intravenous infusion of lidocaine and dexmedetomidine on immediate complications after tonsillectomy surgery in children

Behzad Nazemroaya / Azim Honarmand / Shima Shams

Tehran University Medical Journal, Vol 81, Iss 4, Pp 254-

2023 Volume 263

Abstract: Background: Tonsils are lymphoid tissues of the body's defense system that surround the pharynx and prevent the entry of microbes through inhalation. Tonsillectomy is the final treatment for enlarged tonsils and is one of the most common procedures in ... ...

Abstract	Background: Tonsils are lymphoid tissues of the body's defense system that surround the pharynx and prevent the entry of microbes through inhalation. Tonsillectomy is the final treatment for enlarged tonsils and is one of the most common procedures in the ear, throat and nose. To prevent and improve postoperative complications, various methods are used, including lidocaine and dexmedetomidine injections. The aim of this study was to compare the effects of intravenous infusions of lidocaine and dexmedetomidine on the rate and severity of immediate complications after tonsillectomy surgery. Methods: This study was conducted as a prospective, triple-blind, randomized clinical trial on 96 patients who were candidates for tonsillectomy under general anesthesia at Al-Zahra Hospital, Isfahan, Iran. The patients had informed consents and met the conditions to enter the study. 30 minutes before induction of anesthesia, patients were randomly assigned to one of three groups receiving lidocaine, dexmedetomidine, or placebo. All patients were examined for intraoperative bleeding, laryngospasm in the first 2 hours after the operation, and laryngitis in the first 24 hours after the operation. SPSS version 26 software was used for statistical analysis. Results: The findings of this research indicated that at 45, 75 and, 90 minutes after recovery, the mean score of pain and at 15-90 minutes in terms of anxiety was significantly different from the rest in at least one of the three groups (P<0.05). Systolic blood pressure (SBP) and arterial oxygen blood pressure in minutes 30 to 90, as well as Diastolic blood pressure (DBP) in minutes 60, 75 and 90, showed a significant difference between the three studied groups (P<0.05). There was no significant difference between the incidences of laryngospasm in the groups. However, there was a significant difference between the incidences of bronchospasm in all three groups. In terms of factors such as cough and nausea, no significant differences were observed in the studied groups. ...
Keywords	complications ; dexmedetomidine ; lidocaine ; tonsillectomy ; Medicine (General) ; R5-920
Subject code	610
Language	Persian
Publishing date	2023-07-01T00:00:00Z
Publisher	Tehran University of Medical Sciences
Document type	Article ; Online
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Article ; Online: MiRNAs related in signaling pathways of women's reproductive diseases: an overview.

Bagheri, Malihe / Khansarinejad, Behzad / Mondanizadeh, Mahdieh / Azimi, Mohadeseh / Alavi, Shima

Molecular biology reports

2024 Volume 51, Issue 1, Page(s) 414

Abstract: Background: One of the main health issues that can affect women's health is reproductive diseases, such as polycystic ovary syndrome (PCOS), endometriosis (EMs), uterine leiomyomas (ULs), and ovarian cancer (OC). Although these diseases are very common, ...

Abstract	Background: One of the main health issues that can affect women's health is reproductive diseases, such as polycystic ovary syndrome (PCOS), endometriosis (EMs), uterine leiomyomas (ULs), and ovarian cancer (OC). Although these diseases are very common, we do not have a complete understanding of their underlying cellular and molecular mechanisms. It is important to mention that the majority of patients are diagnosed with these diseases at later stages because of the absence of early diagnostic techniques and dependable molecular indicators. Hence, it is crucial to discover novel and non-invasive biomarkers that have prognostic, diagnostic and therapeutic capabilities. MiRNAs, also known as microRNAs, are small non-coding RNAs that play a crucial role in regulating gene expression at the post-transcriptional level. They are short in length, typically consisting of around 22 nucleotides, and are highly conserved across species. Numerous studies have shown that miRNAs are expressed differently in various diseases and can act as either oncogenes or tumor suppressors. Methods: The author conducted a comprehensive review of all the pertinent papers available in web of science, PubMed, Google Scholar, and Scopus databases. Results: We achieved three goals: providing readers with better information, enhancing search results, and making peer review easier. Conclusions: This review focuses on the investigation of miRNAs and their involvement in various reproductive disorders in women, including their molecular targets. Additionally, it explores the role of miRNAs in the development and progression of these disorders.
MeSH term(s)	Humans ; Female ; MicroRNAs/genetics ; Polycystic Ovary Syndrome/metabolism ; Biomarkers ; Endometriosis ; Signal Transduction
Chemical Substances	MicroRNAs ; Biomarkers
Language	English
Publishing date	2024-03-12
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	186544-4
ISSN	1573-4978 ; 0301-4851
ISSN (online)	1573-4978
ISSN	0301-4851
DOI	10.1007/s11033-024-09357-0
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Article: COVID-19 and RAAS inhibitors: is there a final conclusion?

Talebi-Taher, Mahshid / Najafi, Mohammad Hosein / Behzad, Shima

Iranian journal of microbiology

2022 Volume 13, Issue 6, Page(s) 728–736

Abstract: Coronavirus disease 2019 (COVID-19), the first pandemic caused by a human infecting coronavirus, has drawn global attention from the first time it appeared in Wuhan city of China in late December 2019. Detection of the responsible viral pathogen, named ... ...

Abstract	Coronavirus disease 2019 (COVID-19), the first pandemic caused by a human infecting coronavirus, has drawn global attention from the first time it appeared in Wuhan city of China in late December 2019. Detection of the responsible viral pathogen, named as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by WHO, and its possible pathogenesis lead to the forming of many hypotheses about the factors that may affect the patients' outcome. One of the SARS-CoV-2 infection concerns was the potential role of angiotensin-converting enzyme (ACE) inhibitors and angiotensin-receptor blockers (ARBs) in COVID-19 patients' morbidity and mortality. Studies demonstrated that because SARS-CoV-2 uses human ACE2 cell receptors as an entry receptor to invade the cells, there might be an association between antihypertensive drugs such as RAAS inhibitors (specifically ACEIs and ARBs) and the COVID-19 disease. Data are scarce and conflicting regarding ACEI or ARB consumption and how it influences disease outcomes, and a single conclusion has not been reached yet. According to the literature review in our article, the most evidentially supported theory about the use of RAAS inhibitors in COVID-19 is that these medications, including ACEI/ARB, are not associated with the increased risk of infection, disease severity, and patient prognosis. However, further studies are needed to support the hypothesis.
Language	English
Publishing date	2022-02-10
Publishing country	Iran
Document type	Journal Article ; Review
ZDB-ID	2652849-6
ISSN	2008-4447 ; 2008-3289
ISSN (online)	2008-4447
ISSN	2008-3289
DOI	10.18502/ijm.v13i6.8071
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Article: Microbiological Study of Periodontal Disease in Populations with HIV: a Systematic Review and Meta-Analysis.

Valian, Nasrin K / Houshmand, Behzad / Ardakani, Mohammadreza T / Mahmoudi, Shima

Clinical laboratory

2023 Volume 69, Issue 5

Abstract: Background: No systematic review/meta-analysis has been conducted on the microbiological profile associated with the occurrence of periodontitis in patients with HIV. The aim of this study was to evaluate the prevalence of identified bacteria in HIV- ... ...

Abstract	Background: No systematic review/meta-analysis has been conducted on the microbiological profile associated with the occurrence of periodontitis in patients with HIV. The aim of this study was to evaluate the prevalence of identified bacteria in HIV-infected patients with periodontal disease. Methods: Three English electronic databases (MEDLINE (via PubMed), SCOPUS, and Web of Science) were searched systematically from the beginning to February 13, 2021. The frequency of each identified bacteria in HIV-infected patients with periodontal disease was extracted. All meta-analysis methods were performed using STATA software. Results: Twenty-two articles met inclusion criteria and were enrolled into the systematic review. This review analyzed a total of 965 HIV-infected patients with periodontitis. The prevalence of periodontitis was higher in HIV-infected male patients (83% (CI 95%: 76 - 88%)) compared to females (28% (CI 95%: 17 - 39%)). In our study, the pooled prevalence of necrotizing ulcerative periodontitis and necrotizing ulcerative gingivitis in patients with HIV infection was 67% (CI 95%: 52 - 82%) and 60% (CI 95%: 45 - 74%), while a lower prevalence of linear gingivitis erythema was reported (11% (CI 95%: 5 - 18%)). More than 140 bacterial species were identified from HIV-infected patients with periodontal disease. High prevalence of Tannerella forsythia (51% (CI 95%: 5 - 96%)), Fusobacterium nucleatum (50% (CI 95%: 21 - 78%)), Prevotella intermedia (50% (CI 95%: 32 - 68%)), Peptostreptococcus micros (44% (CI 95%: 25 - 65%)), Campylobacter rectus (35% (CI 95%: 25 - 45%)), and Fusobacterium spp. (35% (CI 95%: 3 - 78%)) in HIV-infected patients with periodontal disease was found. Conclusions: Our study demonstrated that the prevalence of the red and orange complex of bacteria in HIV patients with periodontal disease is relatively high.
MeSH term(s)	Female ; Humans ; Male ; HIV Infections/complications ; HIV Infections/epidemiology ; Porphyromonas gingivalis ; Periodontal Diseases/complications ; Periodontitis/complications ; Periodontitis/microbiology ; Gingivitis/complications ; Gingivitis/microbiology
Language	English
Publishing date	2023-05-05
Publishing country	Germany
Document type	Meta-Analysis ; Systematic Review ; Journal Article ; Review
ZDB-ID	1307629-2
ISSN	1433-6510 ; 0941-2131
ISSN	1433-6510 ; 0941-2131
DOI	10.7754/Clin.Lab.2022.220738
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Article ; Online: Quality of spirometry tests in the field of occupational health

Amirala Alavi Foumani / Seyyed Ali Alavi Foumani / Mirsaeed Attarchi / Alireza Etemadi Deilami / Behzad Majlesi / Shima Ildari / Habib Eslami-Kenarsari

BMC Research Notes, Vol 17, Iss 1, Pp 1-

2024 Volume 5

Abstract: Abstract Background The spirometry test is a valuable test to evaluate the performance of the respiratory system. The interpretation of the results is highly dependent on the quality of its performance, while the inappropriate quality results in unwanted ...

Abstract	Abstract Background The spirometry test is a valuable test to evaluate the performance of the respiratory system. The interpretation of the results is highly dependent on the quality of its performance, while the inappropriate quality results in unwanted consequences for individuals and the healthcare system. This study investigated the quality of spirometry tests performed in occupational health. Methods In this cross-sectional study, the quality of 776 spirometry tests in different occupational centers by the specialists in Rasht, Iran, in 2020, based on the guidelines of the American Thoracic Society (ATS), was investigated. The quality and success rate of the test and the demographical characteristics of the operators and the participants were collected. All data was analyzed using SPSS software version 20. Results Out of 776 spirometry tests, about 69.7% were unacceptable. Among the unacceptable tests, a pause error between inhalation and exhalation was identified in 7.4% of tests. Additionally, 4.6% of the unacceptable tests exhibited a cough error within the first second, while an exhalation error of less than six was observed in 85%. Repeatability errors were found in 60.9% of the tests. Furthermore, among some errors, the communication error between the characteristics of the technicians and the test performance errors were evident. Conclusion According to the results, most of the performed tests were unacceptable with no repeatability, which indicated that the validity and quality of spirometry tests and their interpretation were inappropriate in the field of occupational health in Rasht, Iran.
Keywords	Spirometry ; Quality assessment ; Occupational health ; Medicine ; R ; Biology (General) ; QH301-705.5 ; Science (General) ; Q1-390
Subject code	796
Language	English
Publishing date	2024-01-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
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Article ; Online: Quality of spirometry tests in the field of occupational health.

Alavi Foumani, Amirala / Alavi Foumani, Seyyed Ali / Attarchi, Mirsaeed / Etemadi Deilami, Alireza / Majlesi, Behzad / Ildari, Shima / Eslami-Kenarsari, Habib

BMC research notes

2024 Volume 17, Issue 1, Page(s) 11

Abstract: Background: The spirometry test is a valuable test to evaluate the performance of the respiratory system. The interpretation of the results is highly dependent on the quality of its performance, while the inappropriate quality results in unwanted ... ...

Abstract	Background: The spirometry test is a valuable test to evaluate the performance of the respiratory system. The interpretation of the results is highly dependent on the quality of its performance, while the inappropriate quality results in unwanted consequences for individuals and the healthcare system. This study investigated the quality of spirometry tests performed in occupational health. Methods: In this cross-sectional study, the quality of 776 spirometry tests in different occupational centers by the specialists in Rasht, Iran, in 2020, based on the guidelines of the American Thoracic Society (ATS), was investigated. The quality and success rate of the test and the demographical characteristics of the operators and the participants were collected. All data was analyzed using SPSS software version 20. Results: Out of 776 spirometry tests, about 69.7% were unacceptable. Among the unacceptable tests, a pause error between inhalation and exhalation was identified in 7.4% of tests. Additionally, 4.6% of the unacceptable tests exhibited a cough error within the first second, while an exhalation error of less than six was observed in 85%. Repeatability errors were found in 60.9% of the tests. Furthermore, among some errors, the communication error between the characteristics of the technicians and the test performance errors were evident. Conclusion: According to the results, most of the performed tests were unacceptable with no repeatability, which indicated that the validity and quality of spirometry tests and their interpretation were inappropriate in the field of occupational health in Rasht, Iran.
MeSH term(s)	Humans ; Occupational Health ; Cross-Sectional Studies ; Spirometry/methods ; Exhalation ; Iran
Language	English
Publishing date	2024-01-03
Publishing country	England
Document type	Journal Article
ZDB-ID	2413336-X
ISSN	1756-0500 ; 1756-0500
ISSN (online)	1756-0500
ISSN	1756-0500
DOI	10.1186/s13104-023-06671-x
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Article ; Online: Micropropagation and encapsulation-dehydration method for cryopreservation of Fritillaria imperialis

Shima Seydi / Shahram Sedaghathoor / Behzad Kavyani

مجله بیوتکنولوژی کشاورزی, Vol 13, Iss 2, Pp 125-

2021 Volume 146

Abstract: Objective Fritillaria imperialis from the Liliaceae family is an ornamental species in danger of extinction. Therefore, it is nessessary to conserve the plant genetic pool. Two proper methods to access this goal are micropropagation and germplasm ... ...

Abstract	Objective Fritillaria imperialis from the Liliaceae family is an ornamental species in danger of extinction. Therefore, it is nessessary to conserve the plant genetic pool. Two proper methods to access this goal are micropropagation and germplasm conservation in in vitro freezing conditions. The presence of suitable pre-treatments is necessary for cryopreservation. The most important and the most application of pre-treatment is encapsulation-dehydration. The purpose of current research was in vitro proliferation of F. imperialis using plant growth regulators and its cryopreservation using encapsulation-dehydration pre-treatment. Materials and methods Bulb scales as explants and MS medium as basic culture medium were used. For micropropagation, kinetin (Kin) and α_naphthaleneacetic acid in concentrations of 0 (as control), 0.5, 1 and 2 mg l–1 were applied. For cryopreservation, explants were pretreated with encapsulation-dehydration followed by conservation in liquid nitrogen. Encapsulation was done using sodium alginate. Dehydration was carried out in air and using high level of sucrose. Results The results of micropropagation showed that the maximum number of leaf (3.5) and root number (5.7) was obtained in explants treated with 0.5 mg l–1 Kin along with 1 mg l–1 NAA. The results of cryopreservation showed that encapsulation-dehydration in air as a pre-treatment had effective role on the survival and regeneration of explants (70.5%) after conservation in liquid nitrogen. Least explant survival was obtained in control (without pre-treatment). In vitro regenerated plantlets were cultivated in plastic pots containing peat moss and perlite (in ration of 1:1) and acclimatized with environmental conditions. The survival rate was 90% and the growth pattern of regenerated plants was similar to that of mother plants. Conclusions Present research proposes the use of 0.5 mg l–1 Kin together with 1 mg l–1 NAA for micropropagation and encapsulation-dehydration for germplam cryopreservation of F. imperialis. Micropropagation ...
Keywords	growth regulators ; liliaceae family ; endengered plants ; germplasm conservation ; in vitro culture ; Agriculture ; S ; Biotechnology ; TP248.13-248.65
Subject code	580 ; 500
Language	Persian
Publishing date	2021-06-01T00:00:00Z
Publisher	Shahid Bahonar University of Kerman
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Downregulation of HMGA2 by Small Interfering RNA Affects the Survival, Migration, and Apoptosis of Prostate Cancer Cell Line.

Khajouee, Shima / Baghbani, Elham / Mohammadi, Ali / Mansoori, Behzad / Shanehbandi, Dariush / Hajiasgharzadeh, Khalil / Baradaran, Behzad

Advanced pharmaceutical bulletin

2021 Volume 12, Issue 2, Page(s) 398–403

Abstract: Purpose: ...

Abstract	Purpose:
Language	English
Publishing date	2021-04-03
Publishing country	Iran
Document type	Journal Article
ZDB-ID	3018440-X
ISSN	2251-7308 ; 2228-5881
ISSN (online)	2251-7308
ISSN	2228-5881
DOI	10.34172/apb.2022.039
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The effect of glatiramer acetate, IFNβ-1a, fingolimod, and dimethyl fumarate on the expression of T-bet, IFN-γ, and MEG3 in PBMC of RRMS patients.

Dabbaghi, Rozhin / Safaralizadeh, Reza / Rahmani, Shima / Barpour, Nesa / Hosseinpourfeizi, Mohammadali / Rajabi, Ali / Baradaran, Behzad

BMC research notes

2023 Volume 16, Issue 1, Page(s) 273

Abstract: Objective: Multiple sclerosis (MS) is a progressing neurodegenerative disease marked by chronic central nervous system inflammation and degeneration.This study investigates gene expression profiles of T-box transcription factor TBX21 (T-bet), interferon- ...

Abstract	Objective: Multiple sclerosis (MS) is a progressing neurodegenerative disease marked by chronic central nervous system inflammation and degeneration.This study investigates gene expression profiles of T-box transcription factor TBX21 (T-bet), interferon-gamma (IFN-γ), and long non-coding RNA MEG3 in peripheral blood mononuclear cells (PBMCs) from treatment-naïve Relapsing-Remitting Multiple Sclerosis patients (RRMS), healthy controls, and RRMS patients on different Disease Modifying Therapies (DMTs). The aim is to understand the role of T-bet, IFN-γ, and MEG3 in MS pathogenesis and their potential as diagnostic and therapeutic targets. Results: Elevated T-bet expression is observed in treatment-naïve RRMS patients compared to healthy individuals. RRMS patients treated with Interferon beta-1alpha (IFNβ-1a) and fingolimod exhibit downregulated T-bet and MEG3 expression levels, respectively, with more pronounced effects in females. Healthy individuals show a moderate positive correlation between T-bet and MEG3 and between IFN-γ and T-bet. In RRMS patients treated with Glatiramer Acetate (GA), a strong positive correlation is observed between MEG3 and IFN-γ. Remarkably, RRMS patients treated with Dimethyl Fumarate (DMF) exhibit a significant positive correlation between T-bet and MEG3. These findings underscore the diagnostic potential of T-bet in RRMS, warranting further exploration of MEG3, T-bet, and IFN-γ interplay in RRMS patients.
MeSH term(s)	Female ; Humans ; Glatiramer Acetate/therapeutic use ; Multiple Sclerosis, Relapsing-Remitting/drug therapy ; Multiple Sclerosis, Relapsing-Remitting/genetics ; Fingolimod Hydrochloride/therapeutic use ; Dimethyl Fumarate ; Leukocytes, Mononuclear ; Interferon-gamma/genetics ; Neurodegenerative Diseases ; Multiple Sclerosis/drug therapy
Chemical Substances	Glatiramer Acetate (5M691HL4BO) ; Fingolimod Hydrochloride (G926EC510T) ; Dimethyl Fumarate (FO2303MNI2) ; Interferon-gamma (82115-62-6)
Language	English
Publishing date	2023-10-16
Publishing country	England
Document type	Journal Article
ZDB-ID	2413336-X
ISSN	1756-0500 ; 1756-0500
ISSN (online)	1756-0500
ISSN	1756-0500
DOI	10.1186/s13104-023-06556-z
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