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  1. Book ; Online ; E-Book: Allergens and allergen immunotherapy

    Lockey, Richard F. / Ledford, Dennis K.

    subcutaneous, sublingual and oral

    2020  

    Author's details edited by Richard F. Lockey, Dennis K. Ledford
    Keywords Electronic books
    Language English
    Size 1 Online-Ressource (xix, 577 Seiten), Illustrationen
    Edition Sixth edition
    Publisher CRC Press, Taylor & Francis Group
    Publishing place Boca Raton
    Publishing country United States
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020405060
    ISBN 978-1-351-20898-7 ; 9780815382218 ; 1-351-20898-5 ; 0815382219
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book: Allergens and allergen immunotherapy

    Lockey, Richard F. / Ledford, Dennis K.

    subcuntaneous, sublingual and oral

    2014  

    Author's details ed. by Richard F. Lockey ; Dennis K. Ledford
    Keywords Hypersensitivity / therapy ; Immunotherapy ; Allergens / therapeutic use ; Allergens / immunology
    Language English
    Size XX, 524 S. : zahlr. Ill., graph. Darst.
    Edition 5. ed.
    Publisher CRC Press
    Publishing place Boca Raton u.a.
    Publishing country United States
    Document type Book
    Note Includes bibliographical references and index
    HBZ-ID HT017788768
    ISBN 978-1-84214-573-9 ; 1-84214-573-8
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2014 A 1514 available for loan (reading room) Lesesaal EG

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  3. Book: Asthma

    Ledford, Dennis K. / Lockey, Richard F.

    comorbidities, coexisting conditions, and differential diagnosis

    2014  

    Institution World Allergy Organization
    Author's details ed. by Richard F. Lockey, Dennis K. Ledford. WAO, World Allergy Organization
    Keywords Asthma / complications ; Asthma / diagnosis ; Respiratory Tract Diseases / complications ; Respiratory Tract Diseases / diagnosis ; Diagnosis, Differential
    Language English
    Size XX, 481 S. : Ill, graph. Darst.
    Publisher Oxford Univ. Press
    Publishing place Oxford u.a.
    Publishing country Great Britain
    Document type Book
    Note Includes bibliographical references and index
    HBZ-ID HT018252979
    ISBN 978-0-19-991806-5 ; 0-19-991806-6
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2014 A 1905 available for loan (reading room) Lesesaal EG

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  4. Book: Allergens and allergen immunotherapy

    Lockey, Richard F.

    (Clinical allergy and immunology ; 21)

    2008  

    Author's details ed. by Richard F. Lockey
    Series title Clinical allergy and immunology ; 21
    Collection
    Keywords Hypersensitivity / therapy ; Immunotherapy ; Allergens / therapeutic use ; Allergens / immunology
    Language English
    Size XVI, 550 S., [2] Bl. : Ill., graph. Darst.
    Edition 4. ed.
    Publisher Informa Healthcare
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    Note Includes bibliographical references and index
    HBZ-ID HT015589865
    ISBN 978-1-4200-6197-0 ; 1-4200-6197-6
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2009 A 307 order for loan Magazin

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  5. Article ; Online: Asthma and carotid artery plaques.

    Cardet, Juan Carlos / Weare-Regales, Natalia / Lockey, Richard F

    The Journal of allergy and clinical immunology

    2023  Volume 151, Issue 5, Page(s) 1257–1258

    MeSH term(s) Humans ; Carotid Stenosis ; Inflammation ; Risk Factors ; Asthma
    Language English
    Publishing date 2023-03-02
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 121011-7
    ISSN 1097-6825 ; 1085-8725 ; 0091-6749
    ISSN (online) 1097-6825 ; 1085-8725
    ISSN 0091-6749
    DOI 10.1016/j.jaci.2023.02.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Pyroptosis Inhibition in Disease Treatment: Opportunities and Challenges.

    Bandharam, Navya / Lockey, Richard F / Kolliputi, Narasaiah

    Cell biochemistry and biophysics

    2023  Volume 81, Issue 4, Page(s) 615–619

    Abstract: Programmed cell death (PCD) is at the center of immune responses, with different types of PCD occurring based on bodily conditions at a given moment. The main three types of PCD include pyroptosis, necroptosis, and apoptosis. Both pyroptosis and ... ...

    Abstract Programmed cell death (PCD) is at the center of immune responses, with different types of PCD occurring based on bodily conditions at a given moment. The main three types of PCD include pyroptosis, necroptosis, and apoptosis. Both pyroptosis and necroptosis induce an inflammatory response while apoptosis avoids eliciting an inflammatory reaction. Recently, pyroptosis has come to the forefront of immunology research due to tremendous potential that has been revealed surrounding the regulators of pyroptosis. In addition to previously known regulators of pyroptosis (ZBP1 and NLRP3 genes), a family of proteins called Gasdermin has been discovered. Specifically, Gasdermin D (GSDMD), when cleaved, participates in the onset of pyroptosis of inflammatory diseases. The N-terminal cleaved portion of the molecule causes cellular membrane openings releasing interleukin-18 and IL-1β, inducing pyroptosis. It is hypothesized that the inhibition of GSDMD using drugs such as Dimethyl Fumarate (DMF) and Disulfiram may halt the progression of certain inflammatory diseases including Multiple Sclerosis (MS), autoimmune encephalitis etc. While there is not yet a concrete treatment for pyroptic cell death in inflammatory disease using GSDMD inhibition, there is ample evidence to suggest that there may be success in future studies and therapeutic applications of GSDMD.
    MeSH term(s) Humans ; Pyroptosis ; Intracellular Signaling Peptides and Proteins/metabolism ; Gasdermins ; Apoptosis ; Inflammation/drug therapy ; Inflammasomes/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism
    Chemical Substances Intracellular Signaling Peptides and Proteins ; Gasdermins ; Inflammasomes ; NLR Family, Pyrin Domain-Containing 3 Protein
    Language English
    Publishing date 2023-10-02
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1357904-6
    ISSN 1559-0283 ; 1085-9195
    ISSN (online) 1559-0283
    ISSN 1085-9195
    DOI 10.1007/s12013-023-01181-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  7. Article ; Online: Asthma and Comorbid Conditions.

    Fuhlbrigge, Anne / Lockey, Richard F

    The journal of allergy and clinical immunology. In practice

    2021  Volume 9, Issue 11, Page(s) 3909–3910

    MeSH term(s) Asthma/epidemiology ; Comorbidity ; Humans
    Language English
    Publishing date 2021-11-06
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2021.09.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 7086: Show issues Location:
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  8. Article ; Online: An Intramural Peer-Review Concept to Support Development in Academic Medicine.

    Newcomb, Jennifer D / Lockey, Richard F

    Medical science educator

    2021  Volume 31, Issue 2, Page(s) 411–415

    Abstract: Academic medicine professionals spend their careers striving for promotion and standing in their respective institutions and the global scientific community. Publishing in high-impact journals aids in that pursuit; yet, formal coursework and training ... ...

    Abstract Academic medicine professionals spend their careers striving for promotion and standing in their respective institutions and the global scientific community. Publishing in high-impact journals aids in that pursuit; yet, formal coursework and training rarely emphasize scientific writing, making it difficult to gain the skills necessary to succeed. The authors implemented an intramural peer-review service in the medical school of a preeminent university to offer guidance, resources, and hands-on writing assistance at no cost. This program model bridges a gap in scientific writing instruction, boosts academic productivity, and increases opportunities to publish in higher impact journals.
    Supplementary information: The online version contains supplementary material available at 10.1007/s40670-021-01251-9.
    Language English
    Publishing date 2021-03-02
    Publishing country United States
    Document type Journal Article
    ISSN 2156-8650
    ISSN (online) 2156-8650
    DOI 10.1007/s40670-021-01251-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Patient Communications: Why Is It Important to Quickly Use Epinephrine at the Onset of Symptoms and Signs of Anaphylaxis?

    Collie, James C / Lockey, Richard F

    Immunology and allergy clinics of North America

    2021  Volume 42, Issue 1, Page(s) 201–217

    Abstract: Delayed administration of epinephrine (adrenaline), the first-line and only effective treatment of a systemic allergic reaction (SAR) and anaphylaxis, is associated with increased mortality. However, epinephrine is underused because of a lack of ... ...

    Abstract Delayed administration of epinephrine (adrenaline), the first-line and only effective treatment of a systemic allergic reaction (SAR) and anaphylaxis, is associated with increased mortality. However, epinephrine is underused because of a lack of consensus as to when it should be administered and an inappropriate fear of using epinephrine and potential adverse effects from the medication. The authors emphasize that SARs and anaphylaxis should be considered as a spectrum, and that affected individuals be educated on its safety and repeatedly given instructions as to when and how epinephrine should be used at the first symptoms or signs of SAR and anaphylaxis.
    MeSH term(s) Anaphylaxis/diagnosis ; Epinephrine ; Humans ; Treatment Outcome
    Chemical Substances Epinephrine (YKH834O4BH)
    Language English
    Publishing date 2021-11-22
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 92606-1
    ISSN 1557-8607 ; 0889-8561
    ISSN (online) 1557-8607
    ISSN 0889-8561
    DOI 10.1016/j.iac.2021.09.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Mind-body connection: metabolite 4-ethylphenyl linked to anxiety behavior and oligodendrocyte modification in autism spectrum disorder.

    Pascual, Francisco / Camilli, Samuel / Lockey, Richard F / Kolliputi, Narasaiah

    American journal of physiology. Gastrointestinal and liver physiology

    2023  Volume 324, Issue 6, Page(s) G422–G425

    Abstract: The connection between byproducts of digestion in the gastrointestinal (GI) tract and neurocognitive disorders is an expanding area of research that has implications for autism spectrum disorder (ASD). Needham et al. (Needham et al. ...

    Abstract The connection between byproducts of digestion in the gastrointestinal (GI) tract and neurocognitive disorders is an expanding area of research that has implications for autism spectrum disorder (ASD). Needham et al. (Needham et al.
    MeSH term(s) Animals ; Mice ; Autism Spectrum Disorder/metabolism ; Autism Spectrum Disorder/psychology ; Gastrointestinal Tract/metabolism ; Anxiety ; Brain/metabolism
    Chemical Substances 4-ethylphenyl sulfate
    Language English
    Publishing date 2023-03-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603840-2
    ISSN 1522-1547 ; 0193-1857
    ISSN (online) 1522-1547
    ISSN 0193-1857
    DOI 10.1152/ajpgi.00221.2022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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