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  1. Article ; Online: The Pathogenesis and Long-Term Consequences of COVID-19 Cardiac Injury.

    Siripanthong, Bhurint / Asatryan, Babken / Hanff, Thomas C / Chatha, Salman R / Khanji, Mohammed Y / Ricci, Fabrizio / Muser, Daniele / Ferrari, Victor A / Nazarian, Saman / Santangeli, Pasquale / Deo, Rajat / Cooper, Leslie T / Mohiddin, Saidi A / Chahal, C Anwar A

    JACC. Basic to translational science

    2022  Volume 7, Issue 3, Page(s) 294–308

    Abstract: The mechanisms of coronavirus disease-2019 (COVID-19)-related myocardial injury comprise both direct viral invasion and indirect (hypercoagulability and immune-mediated) cellular injuries. Some patients with COVID-19 cardiac involvement have poor ... ...

    Abstract The mechanisms of coronavirus disease-2019 (COVID-19)-related myocardial injury comprise both direct viral invasion and indirect (hypercoagulability and immune-mediated) cellular injuries. Some patients with COVID-19 cardiac involvement have poor clinical outcomes, with preliminary data suggesting long-term structural and functional changes. These include persistent myocardial fibrosis, edema, and intraventricular thrombi with embolic events, while functionally, the left ventricle is enlarged, with a reduced ejection fraction and new-onset arrhythmias reported in a number of patients. Myocarditis post-COVID-19 vaccination is rare but more common among young male patients. Larger studies, including prospective data from biobanks, will be useful in expanding these early findings and determining their validity.
    Language English
    Publishing date 2022-02-09
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2452-302X
    ISSN (online) 2452-302X
    DOI 10.1016/j.jacbts.2021.10.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Coronavirus disease 2019 is delaying the diagnosis and management of chest pain, acute coronary syndromes, myocarditis and heart failure.

    Siripanthong, Bhurint / Hanff, Thomas C / Levin, Michael G / Vidula, Mahesh K / Khanji, Mohammed Y / Nazarian, Saman / Chahal, Choudhary Anwar A

    Future cardiology

    2020  Volume 17, Issue 1, Page(s) 3–6

    MeSH term(s) Acute Coronary Syndrome/diagnosis ; Acute Coronary Syndrome/epidemiology ; Acute Coronary Syndrome/therapy ; COVID-19/epidemiology ; Chest Pain/diagnosis ; Chest Pain/epidemiology ; Chest Pain/therapy ; Comorbidity ; Disease Management ; Electrocardiography ; Female ; Heart Failure/diagnosis ; Heart Failure/epidemiology ; Heart Failure/therapy ; Humans ; Male ; Middle Aged ; Myocarditis/diagnosis ; Myocarditis/epidemiology ; Myocarditis/therapy ; Pandemics ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-07-01
    Publishing country England
    Document type Editorial ; Research Support, N.I.H., Extramural
    ZDB-ID 2274267-0
    ISSN 1744-8298 ; 1479-6678
    ISSN (online) 1744-8298
    ISSN 1479-6678
    DOI 10.2217/fca-2020-0088
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6836: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Recognizing COVID-19-related myocarditis: The possible pathophysiology and proposed guideline for diagnosis and management.

    Siripanthong, Bhurint / Nazarian, Saman / Muser, Daniele / Deo, Rajat / Santangeli, Pasquale / Khanji, Mohammed Y / Cooper, Leslie T / Chahal, C Anwar A

    Heart rhythm

    2020  Volume 17, Issue 9, Page(s) 1463–1471

    Abstract: Human coronavirus-associated myocarditis is known, and a number of coronavirus disease 19 (COVID-19)-related myocarditis cases have been reported. The pathophysiology of COVID-19-related myocarditis is thought to be a combination of direct viral injury ... ...

    Abstract Human coronavirus-associated myocarditis is known, and a number of coronavirus disease 19 (COVID-19)-related myocarditis cases have been reported. The pathophysiology of COVID-19-related myocarditis is thought to be a combination of direct viral injury and cardiac damage due to the host's immune response. COVID-19 myocarditis diagnosis should be guided by insights from previous coronavirus and other myocarditis experience. The clinical findings include changes in electrocardiogram and cardiac biomarkers, and impaired cardiac function. When cardiac magnetic resonance imaging is not feasible, cardiac computed tomographic angiography with delayed myocardial imaging may serve to exclude significant coronary artery disease and identify myocardial inflammatory patterns. Because many COVID-19 patients have cardiovascular comorbidities, myocardial infarction should be considered. If the diagnosis remains uncertain, an endomyocardial biopsy may help identify active cardiac infection through viral genome amplification and possibly refine the treatment risks of systemic immunosuppression. Arrhythmias are not uncommon in COVID-19 patients, but the pathophysiology is still speculative. Nevertheless, clinicians should be vigilant to provide prompt monitoring and treatment. The long-term impact of COVID-19 myocarditis, including the majority of mild cases, remains unknown.
    MeSH term(s) Arrhythmias, Cardiac/diagnosis ; Arrhythmias, Cardiac/therapy ; Arrhythmias, Cardiac/virology ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Coronavirus Infections/therapy ; Humans ; Myocarditis/diagnosis ; Myocarditis/therapy ; Myocarditis/virology ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/therapy ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2229357-7
    ISSN 1556-3871 ; 1547-5271
    ISSN (online) 1556-3871
    ISSN 1547-5271
    DOI 10.1016/j.hrthm.2020.05.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6278: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: Coronavirus disease 2019 is delaying the diagnosis and management of chest pain, acute coronary syndromes, myocarditis and heart failure

    Siripanthong, Bhurint / Hanff, Thomas C / Levin, Michael G / Vidula, Mahesh K / Khanji, Mohammed Y / Nazarian, Saman / Chahal, Choudhary Anwar A

    Future cardiol

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #622867
    Database COVID19

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  5. Book ; Online: Coronavirus disease 2019 is delaying the diagnosis and management of chest pain, acute coronary syndromes, myocarditis and heart failure

    Siripanthong, Bhurint / Hanff, Thomas C / Levin, Michael G / Vidula, Mahesh K / Khanji, Mohammed Y / Nazarian, Saman / Chahal, Choudhary Anwar A

    2020  

    Keywords Editorial ; acute coronary syndrome ; myocardial injury ; percutaneous coronary intervention ; SARS-CoV-2 ; sepsis-related cardiomyopathy ; ST-elevation myocardial infarction ; stress-induced cardiomyopathy ; thromboembolism ; covid19
    Language English
    Publishing date 2020-07-01T11:03:32Z
    Publisher Future Medicine Ltd
    Publishing country uk
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Recognizing COVID-19–related myocarditis

    Siripanthong, Bhurint / Nazarian, Saman / Muser, Daniele / Deo, Rajat / Santangeli, Pasquale / Khanji, Mohammed Y. / Cooper, Leslie T. / Chahal, C. Anwar A.

    Heart Rhythm

    The possible pathophysiology and proposed guideline for diagnosis and management

    2020  Volume 17, Issue 9, Page(s) 1463–1471

    Keywords Physiology (medical) ; Cardiology and Cardiovascular Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2229357-7
    ISSN 1556-3871 ; 1547-5271
    ISSN (online) 1556-3871
    ISSN 1547-5271
    DOI 10.1016/j.hrthm.2020.05.001
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6278: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

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  7. Article ; Online: State of the Art Review on Genetics and Precision Medicine in Arrhythmogenic Cardiomyopathy.

    Patel, Viraj / Asatryan, Babken / Siripanthong, Bhurint / Munroe, Patricia B / Tiku-Owens, Anjali / Lopes, Luis R / Khanji, Mohammed Y / Protonotarios, Alexandros / Santangeli, Pasquale / Muser, Daniele / Marchlinski, Francis E / Brady, Peter A / Chahal, C Anwar A

    International journal of molecular sciences

    2020  Volume 21, Issue 18

    Abstract: Arrhythmogenic cardiomyopathy (ACM) is an inherited cardiomyopathy characterised by ventricular arrhythmia and an increased risk of sudden cardiac death (SCD). Numerous genetic determinants and phenotypic manifestations have been discovered in ACM, ... ...

    Abstract Arrhythmogenic cardiomyopathy (ACM) is an inherited cardiomyopathy characterised by ventricular arrhythmia and an increased risk of sudden cardiac death (SCD). Numerous genetic determinants and phenotypic manifestations have been discovered in ACM, posing a significant clinical challenge. Further to this, wider evaluation of family members has revealed incomplete penetrance and variable expressivity in ACM, suggesting a complex genotype-phenotype relationship. This review details the genetic basis of ACM with specific genotype-phenotype associations, providing the reader with a nuanced perspective of this condition; whilst also proposing a future roadmap to delivering precision medicine-based management in ACM.
    MeSH term(s) Arrhythmogenic Right Ventricular Dysplasia/classification ; Arrhythmogenic Right Ventricular Dysplasia/diagnostic imaging ; Arrhythmogenic Right Ventricular Dysplasia/genetics ; Cardiac Imaging Techniques ; Genes, Modifier ; Humans ; Magnetic Resonance Imaging
    Keywords covid19
    Language English
    Publishing date 2020-09-10
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms21186615
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Recognizing COVID-19-related myocarditis: The possible pathophysiology and proposed guideline for diagnosis and management

    Siripanthong, Bhurint / Nazarian, Saman / Muser, Daniele / Deo, Rajat / Santangeli, Pasquale / Khanji, Mohammed Y / Cooper, Leslie T / Chahal, C Anwar A

    Heart Rhythm

    Abstract: Human coronavirus-associated myocarditis is known, and a number of coronavirus disease 19 (COVID-19)-related myocarditis cases have been reported. The pathophysiology of COVID-19-related myocarditis is thought to be a combination of direct viral injury ... ...

    Abstract Human coronavirus-associated myocarditis is known, and a number of coronavirus disease 19 (COVID-19)-related myocarditis cases have been reported. The pathophysiology of COVID-19-related myocarditis is thought to be a combination of direct viral injury and cardiac damage due to the host's immune response. COVID-19 myocarditis diagnosis should be guided by insights from previous coronavirus and other myocarditis experience. The clinical findings include changes in electrocardiogram and cardiac biomarkers, and impaired cardiac function. When cardiac magnetic resonance imaging is not feasible, cardiac computed tomographic angiography with delayed myocardial imaging may serve to exclude significant coronary artery disease and identify myocardial inflammatory patterns. Because many COVID-19 patients have cardiovascular comorbidities, myocardial infarction should be considered. If the diagnosis remains uncertain, an endomyocardial biopsy may help identify active cardiac infection through viral genome amplification and possibly refine the treatment risks of systemic immunosuppression. Arrhythmias are not uncommon in COVID-19 patients, but the pathophysiology is still speculative. Nevertheless, clinicians should be vigilant to provide prompt monitoring and treatment. The long-term impact of COVID-19 myocarditis, including the majority of mild cases, remains unknown.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #175974
    Database COVID19

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article ; Online: State of the Art Review on Genetics and Precision Medicine in Arrhythmogenic Cardiomyopathy

    Viraj Patel / Babken Asatryan / Bhurint Siripanthong / Patricia B. Munroe / Anjali Tiku-Owens / Luis R. Lopes / Mohammed Y. Khanji / Alexandros Protonotarios / Pasquale Santangeli / Daniele Muser / Francis E. Marchlinski / Peter A. Brady / C. Anwar A. Chahal

    International Journal of Molecular Sciences, Vol 21, Iss 6615, p

    2020  Volume 6615

    Abstract: Arrhythmogenic cardiomyopathy (ACM) is an inherited cardiomyopathy characterised by ventricular arrhythmia and an increased risk of sudden cardiac death (SCD). Numerous genetic determinants and phenotypic manifestations have been discovered in ACM, ... ...

    Abstract Arrhythmogenic cardiomyopathy (ACM) is an inherited cardiomyopathy characterised by ventricular arrhythmia and an increased risk of sudden cardiac death (SCD). Numerous genetic determinants and phenotypic manifestations have been discovered in ACM, posing a significant clinical challenge. Further to this, wider evaluation of family members has revealed incomplete penetrance and variable expressivity in ACM, suggesting a complex genotype-phenotype relationship. This review details the genetic basis of ACM with specific genotype-phenotype associations, providing the reader with a nuanced perspective of this condition; whilst also proposing a future roadmap to delivering precision medicine-based management in ACM.
    Keywords arrhythmogenic cardiomyopathy ; genetics ; arrhythmogenic right ventricular cardiomyopathy ; desmosome ; cardiac arrhythmia ; sudden cardiac death ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
    Language English
    Publishing date 2020-09-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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