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  1. Article ; Online: K

    Behera, Bipin Kumar / Sahu, Archana Kumari / Devi, Ngangbam Renubala / Saikia, Anil K

    The Journal of organic chemistry

    2021  Volume 86, Issue 18, Page(s) 12481–12493

    Abstract: An efficient methodology has been developed for the synthesis of tetra- and pentasubstituted pyrroles via oxidative self-dimerization ... ...

    Abstract An efficient methodology has been developed for the synthesis of tetra- and pentasubstituted pyrroles via oxidative self-dimerization of
    Language English
    Publishing date 2021-08-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 123490-0
    ISSN 1520-6904 ; 0022-3263
    ISSN (online) 1520-6904
    ISSN 0022-3263
    DOI 10.1021/acs.joc.1c00471
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Augmented weighted K-means grey wolf optimizer: An enhanced metaheuristic algorithm for data clustering problems.

    Premkumar, Manoharan / Sinha, Garima / Ramasamy, Manjula Devi / Sahu, Santhoshini / Subramanyam, Chithirala Bala / Sowmya, Ravichandran / Abualigah, Laith / Derebew, Bizuwork

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 5434

    Abstract: This study presents the K-means clustering-based grey wolf optimizer, a new algorithm intended ... This work mainly focuses on enhancing the grey wolf optimizer using a new weight factor and the K-means ... clustering-inspired fitness function, the K-means clustering-based grey wolf optimizer was extensively ...

    Abstract This study presents the K-means clustering-based grey wolf optimizer, a new algorithm intended to improve the optimization capabilities of the conventional grey wolf optimizer in order to address the problem of data clustering. The process that groups similar items within a dataset into non-overlapping groups. Grey wolf hunting behaviour served as the model for grey wolf optimizer, however, it frequently lacks the exploration and exploitation capabilities that are essential for efficient data clustering. This work mainly focuses on enhancing the grey wolf optimizer using a new weight factor and the K-means algorithm concepts in order to increase variety and avoid premature convergence. Using a partitional clustering-inspired fitness function, the K-means clustering-based grey wolf optimizer was extensively evaluated on ten numerical functions and multiple real-world datasets with varying levels of complexity and dimensionality. The methodology is based on incorporating the K-means algorithm concept for the purpose of refining initial solutions and adding a weight factor to increase the diversity of solutions during the optimization phase. The results show that the K-means clustering-based grey wolf optimizer performs much better than the standard grey wolf optimizer in discovering optimal clustering solutions, indicating a higher capacity for effective exploration and exploitation of the solution space. The study found that the K-means clustering-based grey wolf optimizer was able to produce high-quality cluster centres in fewer iterations, demonstrating its efficacy and efficiency on various datasets. Finally, the study demonstrates the robustness and dependability of the K-means clustering-based grey wolf optimizer in resolving data clustering issues, which represents a significant advancement over conventional techniques. In addition to addressing the shortcomings of the initial algorithm, the incorporation of K-means and the innovative weight factor into the grey wolf optimizer establishes a new standard for further study in metaheuristic clustering algorithms. The performance of the K-means clustering-based grey wolf optimizer is around 34% better than the original grey wolf optimizer algorithm for both numerical test problems and data clustering problems.
    Language English
    Publishing date 2024-03-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-55619-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Author Correction: Augmented weighted K-means grey wolf optimizer: An enhanced metaheuristic algorithm for data clustering problems.

    Premkumar, Manoharan / Sinha, Garima / Ramasamy, Manjula Devi / Sahu, Santhoshini / Subramanyam, Chithirala Bala / Sowmya, Ravichandran / Abualigah, Laith / Derebew, Bizuwork

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 7288

    Language English
    Publishing date 2024-03-27
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-58099-3
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  4. Article ; Online: Stirred tank simulation using Partially-Averaged Navier-Stokes $$k_u-\epsilon _u$$ k u - ϵ u turbulence model

    Srimanta Maji / Akshaya K. Sahu

    SN Applied Sciences, Vol 3, Iss 5, Pp 1-

    2021  Volume 16

    Abstract: ... Averaged Navier-Stokes (PANS) $$k_u-\epsilon _u$$ k u - ϵ u turbulence model has been taken into account ... the experimental data. The main objective is to investigate the influence of different filters width $$f_k$$ f k ... of the PANS $$k_u-\epsilon _u$$ k u - ϵ u model parameter on the characteristic flow variables. The predicted ...

    Abstract Abstract In the present study, simulation of a stirred tank using axial flow impeller has been studied numerically to see the behaviour of flow variables in the entire vessel. It is assumed that the flow is steady state, two dimensional, incompressible and axisymmetric. For simulation, Partially-Averaged Navier-Stokes (PANS) $$k_u-\epsilon _u$$ k u - ϵ u turbulence model has been taken into account. For discretization, control volume method along with upwind and power-law schemes have been taken. The solutions are obtained by using the SIMPLE algorithm. The boundary conditions for impeller are given by using the experimental data. The main objective is to investigate the influence of different filters width $$f_k$$ f k of the PANS $$k_u-\epsilon _u$$ k u - ϵ u model parameter on the characteristic flow variables. The predicted results of the PANS $$k_u-\epsilon _u$$ k u - ϵ u model for different $$f_k$$ f k have been compared with the experimental data at different axial levels of the stirred tank. It has been observed that the power-law scheme gives better agreement with the experimental data. Further, near the impeller region, PANS predicted results are better for smaller $$f_k$$ f k . Also, Reynolds-Averaged Navier-Stokes Shear Stress Transport (SST) $$k-\omega $$ k - ω turbulence model has been tested for comparative study.
    Keywords PANS $$k_u-\epsilon _u$$ k u - ϵ u turbulence model ; SST $$k-\omega $$ k - ω turbulence model ; Control volume method-Stirred vessel ; Axial flow impeller ; Science ; Q ; Technology ; T
    Subject code 532 ; 621
    Language English
    Publishing date 2021-04-01T00:00:00Z
    Publisher Springer
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Beam-Energy Dependence of Directed Flow of Λ, Λ[over ¯], K^{±}, K_{s}^{0}, and ϕ in Au+Au Collisions.

    Adamczyk, L / Adams, J R / Adkins, J K / Agakishiev, G / Aggarwal, M M / Ahammed, Z / Ajitanand, N N / Alekseev, I / Anderson, D M / Aoyama, R / Aparin, A / Arkhipkin, D / Aschenauer, E C / Ashraf, M U / Attri, A / Averichev, G S / Bai, X / Bairathi, V / Barish, K /
    Behera, A / Bellwied, R / Bhasin, A / Bhati, A K / Bhattarai, P / Bielcik, J / Bielcikova, J / Bland, L C / Bordyuzhin, I G / Bouchet, J / Brandenburg, J D / Brandin, A V / Brown, D / Bunzarov, I / Butterworth, J / Caines, H / Calderón de la Barca Sánchez, M / Campbell, J M / Cebra, D / Chakaberia, I / Chaloupka, P / Chang, Z / Chankova-Bunzarova, N / Chatterjee, A / Chattopadhyay, S / Chen, X / Chen, J H / Cheng, J / Cherney, M / Christie, W / Contin, G / Crawford, H J / Das, S / De Silva, L C / Dedovich, T G / Deng, J / Derevschikov, A A / Didenko, L / Dilks, C / Dong, X / Drachenberg, J L / Draper, J E / Dunkelberger, L E / Dunlop, J C / Efimov, L G / Elsey, N / Engelage, J / Eppley, G / Esha, R / Esumi, S / Evdokimov, O / Ewigleben, J / Eyser, O / Fatemi, R / Fazio, S / Federic, P / Federicova, P / Fedorisin, J / Feng, Z / Filip, P / Finch, E / Fisyak, Y / Flores, C E / Fujita, J / Fulek, L / Gagliardi, C A / Garand, D / Geurts, F / Gibson, A / Girard, M / Grosnick, D / Gunarathne, D S / Guo, Y / Gupta, A / Gupta, S / Guryn, W / Hamad, A I / Hamed, A / Harlenderova, A / Harris, J W / He, L / Heppelmann, S / Hirsch, A / Horvat, S / Huang, X / Huang, B / Huang, T / Huang, H Z / Humanic, T J / Huo, P / Igo, G / Jacobs, W W / Jentsch, A / Jia, J / Jiang, K / Jowzaee, S / Judd, E G / Kabana, S / Kalinkin, D / Kang, K / Kapukchyan, D / Kauder, K / Ke, H W / Keane, D / Kechechyan, A / Khan, Z / Kikoła, D P / Kim, C / Kisel, I / Kisiel, A / Kochenda, L / Kocmanek, M / Kollegger, T / Kosarzewski, L K / Kraishan, A F / Krauth, L / Kravtsov, P / Krueger, K / Kulathunga, N / Kumar, L / Kvapil, J / Kwasizur, J H / Lacey, R / Landgraf, J M / Landry, K D / Lauret, J / Lebedev, A / Lednicky, R / Lee, J H / Li, C / Li, X / Li, Y / Li, W / Lidrych, J / Lin, T / Lisa, M A / Liu, P / Liu, H / Liu, Y / Liu, F / Ljubicic, T / Llope, W J / Lomnitz, M / Longacre, R S / Luo, S / Luo, X / Ma, Y G / Ma, L / Ma, R / Ma, G L / Magdy, N / Majka, R / Mallick, D / Margetis, S / Markert, C / Matis, H S / Meehan, K / Mei, J C / Miller, Z W / Minaev, N G / Mioduszewski, S / Mishra, D / Mizuno, S / Mohanty, B / Mondal, M M / Morozov, D A / Mustafa, M K / Nasim, Md / Nayak, T K / Nelson, J M / Nie, M / Nigmatkulov, G / Niida, T / Nogach, L V / Nonaka, T / Nurushev, S B / Odyniec, G / Ogawa, A / Oh, K / Okorokov, V A / Olvitt, D / Page, B S / Pak, R / Pandit, Y / Panebratsev, Y / Pawlik, B / Pei, H / Perkins, C / Pile, P / Pluta, J / Poniatowska, K / Porter, J / Posik, M / Pruthi, N K / Przybycien, M / Putschke, J / Qiu, H / Quintero, A / Ramachandran, S / Ray, R L / Reed, R / Rehbein, M J / Ritter, H G / Roberts, J B / Rogachevskiy, O V / Romero, J L / Roth, J D / Ruan, L / Rusnak, J / Rusnakova, O / Sahoo, N R / Sahu, P K / Salur, S / Sandweiss, J / Saur, M / Schambach, J / Schmah, A M / Schmidke, W B / Schmitz, N / Schweid, B R / Seger, J / Sergeeva, M / Seto, R / Seyboth, P / Shah, N / Shahaliev, E / Shanmuganathan, P V / Shao, M / Sharma, A / Sharma, M K / Shen, W Q / Shi, S S / Shi, Z / Shou, Q Y / Sichtermann, E P / Sikora, R / Simko, M / Singha, S / Skoby, M J / Smirnov, N / Smirnov, D / Solyst, W / Song, L / Sorensen, P / Spinka, H M / Srivastava, B / Stanislaus, T D S / Strikhanov, M / Stringfellow, B / Suaide, A A P / Sugiura, T / Sumbera, M / Summa, B / Sun, Y / Sun, X M / Sun, X / Surrow, B / Svirida, D N / Tang, Z / Tang, A H / Taranenko, A / Tarnowsky, T / Tawfik, A / Thäder, J / Thomas, J H / Timmins, A R / Tlusty, D / Todoroki, T / Tokarev, M / Trentalange, S / Tribble, R E / Tribedy, P / Tripathy, S K / Trzeciak, B A / Tsai, O D / Ullrich, T / Underwood, D G / Upsal, I / Van Buren, G / van Nieuwenhuizen, G / Vasiliev, A N / Videbæk, F / Vokal, S / Voloshin, S A / Vossen, A / Wang, G / Wang, Y / Wang, F / Webb, J C / Webb, G / Wen, L / Westfall, G D / Wieman, H / Wissink, S W / Witt, R / Wu, Y / Xiao, Z G / Xie, G / Xie, W / Xu, J / Xu, Z / Xu, Q H / Xu, Y F / Xu, N / Yang, S / Yang, Y / Yang, C / Yang, Q / Ye, Z / Yi, L / Yip, K / Yoo, I-K / Yu, N / Zbroszczyk, H / Zha, W / Zhang, Z / Zhang, J B / Zhang, J / Zhang, S / Zhang, Y / Zhang, X P / Zhao, J / Zhong, C / Zhou, C / Zhou, L / Zhu, X / Zhu, Z / Zyzak, M

    Physical review letters

    2018  Volume 120, Issue 6, Page(s) 62301

    Abstract: Rapidity-odd directed-flow measurements at midrapidity are presented for Λ, Λ[over ¯], K^{±}, K_{s ...

    Abstract Rapidity-odd directed-flow measurements at midrapidity are presented for Λ, Λ[over ¯], K^{±}, K_{s}^{0}, and ϕ at sqrt[s_{NN}]=7.7, 11.5, 14.5, 19.6, 27, 39, 62.4, and 200 GeV in Au+Au collisions recorded by the Solenoidal Tracker detector at the Relativistic Heavy Ion Collider. These measurements greatly expand the scope of data available to constrain models with differing prescriptions for the equation of state of quantum chromodynamics. Results show good sensitivity for testing a picture where flow is assumed to be imposed before hadron formation and the observed particles are assumed to form via coalescence of constituent quarks. The pattern of departure from a coalescence-inspired sum rule can be a valuable new tool for probing the collision dynamics.
    Language English
    Publishing date 2018-02-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.120.062301
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: HRGPred: Prediction of herbicide resistant genes with k-mer nucleotide compositional features and support vector machine.

    Meher, Prabina Kumar / Sahu, Tanmaya Kumar / Raghunandan, K / Gahoi, Shachi / Choudhury, Nalini Kanta / Rao, Atmakuri Ramakrishna

    Scientific reports

    2019  Volume 9, Issue 1, Page(s) 778

    Abstract: ... of the genes were initially transformed into numeric features based on the k-mer compositions and then supplied ...

    Abstract Herbicide resistance (HR) is a major concern for the agricultural producers as well as environmentalists. Resistance to commonly used herbicides are conferred due to mutation(s) in the genes encoding herbicide target sites/proteins (GETS). Identification of these genes through wet-lab experiments is time consuming and expensive. Thus, a supervised learning-based computational model has been proposed in this study, which is first of its kind for the prediction of seven classes of GETS. The cDNA sequences of the genes were initially transformed into numeric features based on the k-mer compositions and then supplied as input to the support vector machine. In the proposed SVM-based model, the prediction occurs in two stages, where a binary classifier in the first stage discriminates the genes involved in conferring the resistance to herbicides from other genes, followed by a multi-class classifier in the second stage that categorizes the predicted herbicide resistant genes in the first stage into any one of the seven resistant classes. Overall classification accuracies were observed to be ~89% and >97% for binary and multi-class classifications respectively. The proposed model confirmed higher accuracy than the homology-based algorithms viz., BLAST and Hidden Markov Model. Besides, the developed computational model achieved ~87% accuracy, while tested with an independent dataset. An online prediction server HRGPred ( http://cabgrid.res.in:8080/hrgpred ) has also been established to facilitate the prediction of GETS by the scientific community.
    MeSH term(s) Algorithms ; Computational Biology/methods ; Gene Expression Regulation, Plant ; Herbicide Resistance ; Models, Genetic ; Plant Proteins/genetics ; Plants/genetics ; Sequence Analysis, DNA ; Sequence Homology, Nucleic Acid ; Support Vector Machine
    Chemical Substances Plant Proteins
    Language English
    Publishing date 2019-01-28
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-018-37309-9
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  7. Article ; Online: Zymography assisted quick purification, characterization and inhibition analysis of K. pneumoniae alkaline phosphatase by mercury and thiohydroxyal compounds.

    Gupta, Sangam / Paul, Manish / Sahu, Santosh Kumar

    Protein expression and purification

    2022  Volume 201, Page(s) 106185

    Abstract: ... to locate precisely the K. pneumoniae alkaline phosphatase (Kp-ALKP) on 7% native PAGE. Subsequent removal ... of the yellow-stained band and electroelution yielded a 54 kDa, Kp-ALKP with K ...

    Abstract In-gel hydrolysis of para-nitrophenyl phosphate (p-NPP) to yellow colored para-nitrophenol was used to locate precisely the K. pneumoniae alkaline phosphatase (Kp-ALKP) on 7% native PAGE. Subsequent removal of the yellow-stained band and electroelution yielded a 54 kDa, Kp-ALKP with K
    MeSH term(s) Alkaline Phosphatase/genetics ; Disulfides ; Edetic Acid ; Hydrogen-Ion Concentration ; Kinetics ; Lead ; Mercaptoethanol ; Mercury ; Nitrophenols ; Phosphates ; Trypsin
    Chemical Substances Disulfides ; Nitrophenols ; Phosphates ; Lead (2P299V784P) ; Mercaptoethanol (60-24-2) ; Edetic Acid (9G34HU7RV0) ; Alkaline Phosphatase (EC 3.1.3.1) ; Trypsin (EC 3.4.21.4) ; Mercury (FXS1BY2PGL)
    Language English
    Publishing date 2022-10-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1055455-5
    ISSN 1096-0279 ; 1046-5928
    ISSN (online) 1096-0279
    ISSN 1046-5928
    DOI 10.1016/j.pep.2022.106185
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  8. Book ; Online: A First-principles study on ABBr3 (A = Cs, Rb, K, Na; B = Ge, Sn) halide perovskites for photovoltaic applications

    Saikia, Dibyajyoti / Alam, Mahfooz / Bera, Jayanta / Betal, Atanu / Gandhi, Appala Naidu / Sahu, Satyajit

    2022  

    Abstract: ... for solar cell applications, we performed first-principles calculations of ABBr3 perovskites (A = Cs, Rb, K, and ...

    Abstract In recent years, halide perovskite-based solar cells have received intensive attention, and demonstrated power conversion efficiency as high as 25.8%. With regard to the toxicity of Pb and the instability of organic elements, all inorganic lead-free perovskites (ILPs) have been extensively studied to achieve comparable or greater photovoltaic performance. In order to develop ILPs as an alternative for solar cell applications, we performed first-principles calculations of ABBr3 perovskites (A = Cs, Rb, K, and Na, and B = Sn, and Ge). Structural, electronic, and optical properties were systematically studied to probe the potentiality in photovoltaic applications. All these ILPs exhibited a direct bandgap in the range of 1.10 to 1.97 eV, highly beneficial for absorbing solar energy. Furthermore, these ILPs demonstrated significant optical absorption (over 105 cm-1) in the whole UV-Vis spectrum. These results will be helpful for designing highly efficient lead-free perovskite solar cells.

    Comment: 25 pages, 11 figures, 5 tables
    Keywords Condensed Matter - Materials Science
    Publishing date 2022-05-03
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Acclimation of brackish water pearl spot (Etroplus suratensis) to various salinities: relative changes in abundance of branchial Na(+)/K (+)-ATPase and Na (+)/K (+)/2Cl (-) co-transporter in relation to osmoregulatory parameters.

    Chandrasekar, S / Nich, T / Tripathi, G / Sahu, N P / Pal, A K / Dasgupta, S

    Fish physiology and biochemistry

    2014  Volume 40, Issue 3, Page(s) 983–996

    Abstract: ... Although the plasma osmolality and Na(+), K(+) and Cl(-) levels increased with the increasing salinities ... revealed that Na(+)/K(+)-ATPase immunoreactive (NKA-IR) cells were mainly distributed in the interlamellar ... than their FW counterparts. Besides, the relative abundance of branchial Na(+)/K(+)/2Cl(-) co-transporter showed ...

    Abstract The present study was conducted to elucidate the osmoregulatory ability of the fish pearl spot (Etroplus suratensis) to know the scope of this species for aquaculture under various salinities. Juvenile pearl spot were divided into three groups and acclimated to freshwater (FW), brackish water (BW) or seawater (SW) for 15 days. The fish exhibited effective salinity tolerance under osmotic challenges. Although the plasma osmolality and Na(+), K(+) and Cl(-) levels increased with the increasing salinities, the parameters remained within the physiological range. The muscle water contents were constant among FW-, BW- and SW-acclimated fish. Two Na+/K+-ATPase α-isoforms (NKA α) were expressed in gills during acclimation in FW, BW and SW. Abundance of one isoform was up-regulated in response to seawater acclimation, suggesting its role in ion secretion similar to NKA α1b, while expression of another isoform was simultaneously up-regulated in response to both FW and SW acclimation, suggesting the presence of isoforms switching phenomenon during acclimation to different salinities. Nevertheless, NKA enzyme activities in the gills of the SW and FW individuals were higher (p < 0.05) than in BW counterparts. Immunohistochemistry revealed that Na(+)/K(+)-ATPase immunoreactive (NKA-IR) cells were mainly distributed in the interlamellar region of the gill filaments in FW groups and in the apical portion of the filaments in BW and SW groups. The number of NKA-IR cells in the gills of the FW-acclimated fish was almost similar to that of SW individuals, which exceeded that of the BW individuals. The NKA-IR cells of BW and SW were bigger in size than their FW counterparts. Besides, the relative abundance of branchial Na(+)/K(+)/2Cl(-) co-transporter showed stronger evidence in favor of involvement of this protein in hypo-osmoregulation, requiring ion secretion by the chloride cells. To the best of our knowledge, this is the first study reporting the wide salinity tolerance of E. suratensis involving differential activation of ion transporters and thereby suggesting its potential as candidate for fish farming under different external salinities.
    MeSH term(s) Acclimatization ; Animals ; Cichlids/physiology ; Gills/enzymology ; Muscles/metabolism ; Osmoregulation ; Random Allocation ; Salinity ; Sodium-Potassium-Chloride Symporters/metabolism ; Sodium-Potassium-Exchanging ATPase/metabolism
    Chemical Substances Sodium-Potassium-Chloride Symporters ; Sodium-Potassium-Exchanging ATPase (EC 7.2.2.13)
    Language English
    Publishing date 2014-01-31
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 292907-7
    ISSN 1573-5168 ; 0920-1742
    ISSN (online) 1573-5168
    ISSN 0920-1742
    DOI 10.1007/s10695-013-9899-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Percutaneous K wire fixation in pediatric lateral condylar fractures of humerus: A prospective study.

    Lal Sahu, R

    Revista espanola de cirugia ortopedica y traumatologia

    2017  Volume 62, Issue 1, Page(s) 1–7

    Abstract: Background: We evaluated the radiographic and clinical functional results of K-wire fixation ... fractures of the humerus. All the patients were treated by close reduction and internal fixation with two K-wires for three ... removing pins and oral antibiotic administration.: Conclusion: Percutaneous K-wire fixation is ...

    Title translation Fijación percutánea del alambre K en las fracturas condilares laterales pediátricas del húmero: un estudio prospectivo.
    Abstract Background: We evaluated the radiographic and clinical functional results of K-wire fixation in the treatment of displaced lateral condyle fractures of the humerus.
    Materials and methods: A prospective longitudinal study was undertaken in our hospital during the period December 2010-December 2014. A total number of 85 children (18 girls and 67 boys) mean age 7.76 years; range 2-13 years with displaced (>2mm) lateral condyle fractures of the humerus. All the patients were treated by close reduction and internal fixation with two K-wires for three weeks. The fractures were classified according to the criteria by Milch and Badelon and functional results were evaluated according to the criteria by Hardacre et al. The mean follow-up period was 24 months (range: 20-28 months).
    Results: All children achieved union in a mean time of 3 weeks (range: 2.5-6 weeks). Functional results were excellent in 91.75% children and good in 7.05% children. Full range of elbow motion was achieved in all the patients. None of the patients had instability postoperatively. Post-operatively, 5.88% children got pin tract infection, which was superficial and healed after removing pins and oral antibiotic administration.
    Conclusion: Percutaneous K-wire fixation is an effective treatment for unstable displaced lateral condylar fractures of the humerus in children. If fracture displacement after closed reduction exceeds 2mm, open reduction and internal fixation is recommended.
    MeSH term(s) Adolescent ; Bone Wires ; Child ; Child, Preschool ; Female ; Fracture Fixation, Internal/instrumentation ; Fracture Fixation, Internal/methods ; Humans ; Humeral Fractures/diagnostic imaging ; Humeral Fractures/surgery ; Longitudinal Studies ; Male ; Prospective Studies ; Radiography ; Treatment Outcome
    Language Spanish
    Publishing date 2017-11-20
    Document type Clinical Trial ; Journal Article
    ISSN 2173-576X
    ISSN (online) 2173-576X
    DOI 10.1016/j.recot.2017.10.005
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