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  1. Article ; Online: Pre-existing Autoimmune Diseases and Immune Checkpoint Inhibitors for Cancer Treatment: Considerations About Initiation, Flares, Immune-Related Adverse Events, and Cancer Progression.

    Sparks, Jeffrey A

    Rheumatic diseases clinics of North America

    2024  Volume 50, Issue 2, Page(s) 147–159

    Abstract: Immune checkpoint inhibitors (ICIs) are increasingly used to treat a variety of cancer types. Patients with preexisting autoimmune diseases may be vulnerable to underlying disease flare as well as immune-related adverse events from ICIs. There has also ... ...

    Abstract Immune checkpoint inhibitors (ICIs) are increasingly used to treat a variety of cancer types. Patients with preexisting autoimmune diseases may be vulnerable to underlying disease flare as well as immune-related adverse events from ICIs. There has also been concern that immunosuppression needed to control the autoimmune disease may blunt ICI efficacy. Much of the literature is focused on diverse preexisting autoimmune diseases, which may limit conclusions to specific diseases. There is a growing literature of specific diseases, such as preexisting rheumatoid arthritis, investigating outcomes after ICI.
    MeSH term(s) Humans ; Immune Checkpoint Inhibitors/adverse effects ; Neoplasms/immunology ; Neoplasms/drug therapy ; Autoimmune Diseases/drug therapy ; Autoimmune Diseases/immunology ; Autoimmune Diseases/chemically induced ; Disease Progression ; Symptom Flare Up
    Chemical Substances Immune Checkpoint Inhibitors
    Language English
    Publishing date 2024-02-23
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 92118-x
    ISSN 1558-3163 ; 0889-857X
    ISSN (online) 1558-3163
    ISSN 0889-857X
    DOI 10.1016/j.rdc.2024.01.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Multimorbidity Accrual After Incident Rheumatoid Arthritis: A Wolf at the Door.

    Sparks, Jeffrey A

    The Journal of rheumatology

    2021  Volume 48, Issue 11, Page(s) 1629–1631

    MeSH term(s) Arthritis, Rheumatoid/epidemiology ; Comorbidity ; Humans ; Multimorbidity
    Language English
    Publishing date 2021-06-01
    Publishing country Canada
    Document type Editorial
    ZDB-ID 194928-7
    ISSN 1499-2752 ; 0315-162X
    ISSN (online) 1499-2752
    ISSN 0315-162X
    DOI 10.3899/jrheum.210224
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Towards clinical significance of the

    Sparks, Jeffrey A

    Annals of the rheumatic diseases

    2021  Volume 80, Issue 12, Page(s) 1503–1504

    MeSH term(s) Arthritis, Rheumatoid/complications ; Arthritis, Rheumatoid/genetics ; Humans ; Lung Diseases, Interstitial/genetics ; Mucin-5B/genetics ; Promoter Regions, Genetic
    Chemical Substances MUC5B protein, human ; Mucin-5B
    Language English
    Publishing date 2021-08-03
    Publishing country England
    Document type Editorial ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 7090-7
    ISSN 1468-2060 ; 0003-4967
    ISSN (online) 1468-2060
    ISSN 0003-4967
    DOI 10.1136/annrheumdis-2021-220856
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Bi-directional association of rheumatoid arthritis and chronic obstructive pulmonary disease: Linking arthritis, inflammation, smoking, airways disease, and emphysema.

    Ford, Julia A / Cho, Michael H / Sparks, Jeffrey A

    Rheumatology (Oxford, England)

    2024  

    Language English
    Publishing date 2024-03-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 1464822-2
    ISSN 1462-0332 ; 1462-0324
    ISSN (online) 1462-0332
    ISSN 1462-0324
    DOI 10.1093/rheumatology/keae137
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Pulmonary Damage Biomarkers for Risk of Rheumatoid Arthritis-Associated Interstitial Lung Disease: Enabling Early Detection and Risk Stratification.

    Juge, Pierre-Antoine / Dellaripa, Paul F / Sparks, Jeffrey A

    Arthritis & rheumatology (Hoboken, N.J.)

    2024  

    Language English
    Publishing date 2024-02-15
    Publishing country United States
    Document type Editorial
    ZDB-ID 2756371-6
    ISSN 2326-5205 ; 2326-5191
    ISSN (online) 2326-5205
    ISSN 2326-5191
    DOI 10.1002/art.42827
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Clinical application of personalized rheumatoid arthritis risk information: Translational epidemiology leading to precision medicine.

    Sparks, Jeffrey A

    Expert review of precision medicine and drug development

    2020  Volume 6, Issue 3, Page(s) 147–149

    Language English
    Publishing date 2020-12-14
    Publishing country England
    Document type Journal Article
    ISSN 2380-8993
    ISSN 2380-8993
    DOI 10.1080/23808993.2021.1857237
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Therapeutic Drug Monitoring for Immune-Mediated Inflammatory Diseases.

    Wallace, Zachary S / Sparks, Jeffrey A

    JAMA

    2022  Volume 326, Issue 23, Page(s) 2370–2372

    MeSH term(s) Drug Monitoring ; Gastrointestinal Agents ; Infliximab
    Chemical Substances Gastrointestinal Agents ; Infliximab (B72HH48FLU)
    Language English
    Publishing date 2022-01-06
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2021.21315
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Occupational inhalants, genetics and the respiratory mucosal paradigm for ACPA-positive rheumatoid arthritis.

    Kronzer, Vanessa L / Sparks, Jeffrey A

    Annals of the rheumatic diseases

    2022  Volume 82, Issue 3, Page(s) 303–305

    MeSH term(s) Humans ; Arthritis, Rheumatoid/genetics ; Risk Factors ; Autoantibodies ; Peptides, Cyclic
    Chemical Substances Autoantibodies ; Peptides, Cyclic
    Language English
    Publishing date 2022-12-06
    Publishing country England
    Document type Editorial ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 7090-7
    ISSN 1468-2060 ; 0003-4967
    ISSN (online) 1468-2060
    ISSN 0003-4967
    DOI 10.1136/ard-2022-223286
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Improving COVID-19 vaccine immunogenicity by interrupting methotrexate treatment.

    Sparks, Jeffrey A / Tedeschi, Sara K

    The Lancet. Respiratory medicine

    2022  Volume 10, Issue 9, Page(s) 813–815

    MeSH term(s) COVID-19/prevention & control ; COVID-19 Vaccines ; Humans ; Immunogenicity, Vaccine ; Immunosuppressive Agents ; Methotrexate/therapeutic use
    Chemical Substances COVID-19 Vaccines ; Immunosuppressive Agents ; Methotrexate (YL5FZ2Y5U1)
    Language English
    Publishing date 2022-06-27
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2686754-0
    ISSN 2213-2619 ; 2213-2600
    ISSN (online) 2213-2619
    ISSN 2213-2600
    DOI 10.1016/S2213-2600(22)00224-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: No association of bariatric surgery with reduced rheumatoid arthritis risk: where do we go from here?

    Sparks, Jeffrey A

    Rheumatology (Oxford, England)

    2019  Volume 59, Issue 2, Page(s) 275–276

    MeSH term(s) Arthritis, Rheumatoid ; Bariatric Surgery ; Humans ; Incidence ; Obesity ; Sweden
    Language English
    Publishing date 2019-11-04
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 1464822-2
    ISSN 1462-0332 ; 1462-0324
    ISSN (online) 1462-0332
    ISSN 1462-0324
    DOI 10.1093/rheumatology/kez521
    Database MEDical Literature Analysis and Retrieval System OnLINE

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