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  1. Article ; Online: Validity of the minimum data set for outcomes research in patients hospitalized for heart failure in Spain.

    Bernal, José L / Bonilla-Palomas, Juan Luis / Rosillo, Nicolás / Bonanad, Clara / Elola, Javier / Anguita, Manuel

    Revista espanola de cardiologia (English ed.)

    2023  Volume 76, Issue 11, Page(s) 938–939

    MeSH term(s) Humans ; Spain/epidemiology ; Hospitalization ; Outcome Assessment, Health Care ; Heart Failure/epidemiology ; Heart Failure/therapy
    Language Spanish
    Publishing date 2023-07-16
    Publishing country Spain
    Document type Case Reports
    ZDB-ID 2592481-3
    ISSN 1885-5857 ; 1885-5857
    ISSN (online) 1885-5857
    ISSN 1885-5857
    DOI 10.1016/j.rec.2023.05.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Circadian Rhythms and Acute Coronary Syndrome in the Elderly.

    de Rueda, Clemencia / Díez-Villanueva, Pablo / Bonanad, Clara / Alfonso, Fernando

    Frontiers in bioscience (Landmark edition)

    2022  Volume 27, Issue 3, Page(s) 82

    Abstract: Ischemic heart disease is the leading cause of death in Western countries. The incidence, prevalence and mortality rate of acute cardiac events increase with age. Circadian rhythms allow organisms to prepare for their daily fluctuations brought on by day- ...

    Abstract Ischemic heart disease is the leading cause of death in Western countries. The incidence, prevalence and mortality rate of acute cardiac events increase with age. Circadian rhythms allow organisms to prepare for their daily fluctuations brought on by day-night cycles, thus playing an important role in the cardiovascular physiology. This can be sometimes a double-edged sword, since exaggerated responses may not be beneficial or may be even harmful in individuals susceptible to adverse acute cardiovascular events. Remarkably, occurrence of such events has been related to a circadian pattern with a peak in the morning hours. Of interest, elderly patients seem to have an increased risk of acute coronary events, especially in the morning, though a bimodal distribution has also been observed. Further studies are required to get more insights on age-related differential circadian patterns in acute coronary syndromes patients.
    MeSH term(s) Acute Coronary Syndrome ; Aged ; Cardiovascular System ; Circadian Rhythm/physiology ; Heart ; Humans
    Language English
    Publishing date 2022-03-28
    Publishing country Singapore
    Document type Journal Article ; Review
    ZDB-ID 2704569-9
    ISSN 2768-6698 ; 2768-6698
    ISSN (online) 2768-6698
    ISSN 2768-6698
    DOI 10.31083/j.fbl2703082
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Oral Anticoagulant Use and Appropriateness in Elderly Patients with Atrial Fibrillation in Complex Clinical Conditions: ACONVENIENCE Study.

    Bonanad, Clara / Formiga, Francesc / Anguita, Manuel / Petidier, Roberto / Gullón, Alejandra

    Journal of clinical medicine

    2022  Volume 11, Issue 24

    Abstract: Non-valvular atrial fibrillation (NVAF) is the most common arrhythmia in older patients. Although direct-acting oral anticoagulants (DOAC) are the antithrombotic treatment of choice, irrespective of age, certain factors may limit their use. The aim of ... ...

    Abstract Non-valvular atrial fibrillation (NVAF) is the most common arrhythmia in older patients. Although direct-acting oral anticoagulants (DOAC) are the antithrombotic treatment of choice, irrespective of age, certain factors may limit their use. The aim of the ACONVENIENCE study was to consult the opinion of a multidisciplinary panel of experts on the appropriateness of using OACs in elderly patients (>75 years) with NVAF associated with certain complex clinical conditions. A consensus project was performed on the basis of a systematic review of the literature, and application of a two-round Delphi survey. The agreement of 79 panellists on 30 Delphi-type statements was evaluated, and their opinion on the appropriateness of different oral anticoagulants in 16 complex clinical scenarios was assessed. A total of 27 consensus statements were agreed upon, including all statements addressing anticoagulation in older patients and in patients at high risk of bleeding complications, and most of those addressing frailty, dementia, risk of falling, and complex cardiac situations. It was almost unanimously agreed upon that advanced age should not influence the anticoagulation decision. Apixaban was the highest-rated therapeutic option in 14/16 situations, followed by edoxaban. There is a high degree of agreement on anticoagulation in older patients with NVAF. Age should not be the single limiting factor when prescribing OACs, and the decision should be made based on net clinical benefit and a comprehensive geriatric assessment. Apixaban, followed by edoxaban, was considered the most appropriate treatment in the various complex clinical situations examined.
    Language English
    Publishing date 2022-12-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm11247423
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Carbohydrate antigen 125-guided pre-TAVI medical optimization: impact on quality of life and clinical outcomes.

    García-Blas, Sergio / Pernias, Vicente / González D'gregorio, Jessika / Fernández-Cisnal, Agustín / Bonanad, Clara / Sastre, Clara / Valero, Ernesto / Miñana, Gema / Zaharia, Georgiana / Núñez, Julio / Sanchis, Juan

    Revista espanola de cardiologia (English ed.)

    2024  

    Abstract: Introduction and objectives: Carbohydrate antigen 125 (CA125), a biomarker associated with fluid overload, has proven useful in managing diuretic therapy in heart failure. We aimed to evaluate the impact of diuretic optimization guided by CA125 before ... ...

    Abstract Introduction and objectives: Carbohydrate antigen 125 (CA125), a biomarker associated with fluid overload, has proven useful in managing diuretic therapy in heart failure. We aimed to evaluate the impact of diuretic optimization guided by CA125 before transcatheter aortic valve implantation (TAVI) on outcomes.
    Methods: This prospective interventional study enrolled patients scheduled for TAVI, in whom baseline CA125 was measured 2 weeks before TAVI. Patients with CA125 ≥ 20 U/mL underwent diuretic up-titration before TAVI. Three groups were included: group I) baseline CA125 <20 U/mL; IIa) CA125 ≥ 20 U/mL that decreased after treatment, and IIb) CA125 ≥ 20 U/mL that did not decrease. The primary outcome was changes in the Kansas City Cardiomyopathy Questionnaire at 3 and 12 months. The secondary endpoint was clinical events.
    Results: The study included 184 patients (115 group I, 46 IIa, and 23 IIb). Groups I and IIa exhibited early and sustained improvements in the Kansas City Cardiomyopathy Questionnaire (group I: 18.9 points [95%CI, 15.7-22.1; P <.001] at 90 days, and 18.1 [95%CI, 14.9-21.4, P <.001] at 1 year; group IIa: 21.1 points [95%CI, 15.4-26.7; P <.001] and 19.5 [95%CI, 13.9-25.1; P <.001] respectively). In contrast, in group IIb there was no significant improvement at 90 days (P=.12), with improvement being significant only at 1 year (17.8 points, 95%CI, 5.9-29.6; P=.003). Over a median follow-up of 20.7 months, there were 63 (27.83%) deaths or heart failure admissions. Multivariate analysis showed a lower risk of events in group I vs IIb (HR, 0.28; 95%CI, 0.14-0.58; P <.001), and IIa vs IIb (HR, 0.24; 95%CI, 0.11-0.55; P <.001).
    Conclusions: Patients with persistently high CA125 despite diuretic therapy pre-TAVI showed slower functional recovery and poorer clinical outcomes after TAVI.
    Language Spanish
    Publishing date 2024-02-02
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 2592481-3
    ISSN 1885-5857 ; 1885-5857
    ISSN (online) 1885-5857
    ISSN 1885-5857
    DOI 10.1016/j.rec.2024.01.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Hitos de la Sección de Cardiología Geriátrica de la Sociedad Española de Cardiología: la r-evolución desde 1995 a 2020.

    Bonanad, Clara / Guerrero, Carme / Bianchi, Claudia

    Revista espanola de cardiologia

    2020  Volume 73, Issue 12, Page(s) 981–984

    Title translation Milestones of the Section on Geriatric Cardiology of the Spanish Society of Cardiology: the r-evolution from 1995 to 2020.
    Keywords covid19
    Language Spanish
    Publishing date 2020-06-27
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 128925-1
    ISSN 1579-2242 ; 0300-8932
    ISSN (online) 1579-2242
    ISSN 0300-8932
    DOI 10.1016/j.recesp.2020.06.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 215: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
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  6. Article ; Online: Milestones of the Section on Geriatric Cardiology of the Spanish Society of Cardiology: the r-evolution from 1995 to 2020.

    Bonanad, Clara / Guerrero, Carme / Bianchi, Claudia

    Revista espanola de cardiologia (English ed.)

    2020  Volume 73, Issue 12, Page(s) 981–984

    MeSH term(s) Aged ; Cardiology ; Humans ; Societies, Medical ; Spain
    Language Spanish
    Publishing date 2020-08-11
    Publishing country Spain
    Document type Editorial
    ZDB-ID 2592481-3
    ISSN 1885-5857 ; 1885-5857
    ISSN (online) 1885-5857
    ISSN 1885-5857
    DOI 10.1016/j.rec.2020.06.028
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Circadian Rhythms and Acute Coronary Syndrome in the Elderly

    Clemencia de Rueda / Pablo Díez-Villanueva / Clara Bonanad / Fernando Alfonso

    Frontiers in Bioscience-Landmark, Vol 27, Iss 3, p

    2022  Volume 082

    Abstract: Ischemic heart disease is the leading cause of death in Western countries. The incidence, prevalence and mortality rate of acute cardiac events increase with age. Circadian rhythms allow organisms to prepare for their daily fluctuations brought on by day- ...

    Abstract Ischemic heart disease is the leading cause of death in Western countries. The incidence, prevalence and mortality rate of acute cardiac events increase with age. Circadian rhythms allow organisms to prepare for their daily fluctuations brought on by day-night cycles, thus playing an important role in the cardiovascular physiology. This can be sometimes a double-edged sword, since exaggerated responses may not be beneficial or may be even harmful in individuals susceptible to adverse acute cardiovascular events. Remarkably, occurrence of such events has been related to a circadian pattern with a peak in the morning hours. Of interest, elderly patients seem to have an increased risk of acute coronary events, especially in the morning, though a bimodal distribution has also been observed. Further studies are required to get more insights on age-related differential circadian patterns in acute coronary syndromes patients.
    Keywords circadian rhythm ; acute coronary syndrome ; elderly ; Biochemistry ; QD415-436 ; Biology (General) ; QH301-705.5
    Subject code 610
    Language English
    Publishing date 2022-03-01T00:00:00Z
    Publisher IMR Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Inflammation as a New Therapeutic Target among Older Patients with Ischemic Heart Disease.

    Maidana, Daniela / Arroyo-Álvarez, Andrea / Arenas-Loriente, Andrea / Barreres-Martín, Guillermo / Muñoz-Alfonso, Carles / Bompart Berroteran, Daznia / Esteve Claramunt, Francisca / Blanco Del Burgo, Regina / Cepas-Guillén, Pedro / Garcia-Blas, Sergio / Bonanad, Clara

    Journal of clinical medicine

    2024  Volume 13, Issue 2

    Abstract: Cardiovascular (CV) diseases remain a global health challenge, with ischemic heart disease (IHD) being the primary cause of both morbidity and mortality. Despite optimal pharmacological therapy, older patients with IHD exhibit an increased susceptibility ...

    Abstract Cardiovascular (CV) diseases remain a global health challenge, with ischemic heart disease (IHD) being the primary cause of both morbidity and mortality. Despite optimal pharmacological therapy, older patients with IHD exhibit an increased susceptibility to recurrent ischemic events, significantly impacting their prognosis. Inflammation is intricately linked with the aging process and plays a pivotal role in the evolution of atherosclerosis. Emerging anti-inflammatory therapies have shown promise in reducing ischemic events among high-risk populations. This review aims to explore the potential of targeted anti-inflammatory interventions in improving clinical outcomes and the quality of life for older patients with IHD.
    Language English
    Publishing date 2024-01-09
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13020363
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: El paciente mayor con síndrome cardiorrenal: de riñón a corazón y vuelta a empezar.

    Núñez-Marín, Gonzalo / Martín-Sánchez, Francisco Javier / Bonanad, Clara

    Revista espanola de geriatria y gerontologia

    2020  Volume 56, Issue 1, Page(s) 1–2

    Title translation Cardiorenal Syndrome in Elderly: An Endless Loop Between Heart and Kidneys.
    MeSH term(s) Aged ; Cardio-Renal Syndrome ; Heart Failure ; Humans ; Kidney
    Language Spanish
    Publishing date 2020-12-25
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 605609-x
    ISSN 1578-1747 ; 0211-139X
    ISSN (online) 1578-1747
    ISSN 0211-139X
    DOI 10.1016/j.regg.2020.10.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2677: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
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  10. Article ; Online: Second victims and quality of support resources among cardiology professionals.

    Bañeras, Jordi / Jorge-Pérez, Pablo / Bonanad, Clara / López Lluva, María Thiscal / Moll, Isaac / Fidel Kinori, Sara Guila

    Revista espanola de cardiologia (English ed.)

    2022  Volume 75, Issue 8, Page(s) 686–688

    MeSH term(s) Cardiology ; Health Personnel ; Humans ; Stress, Psychological
    Language Spanish
    Publishing date 2022-03-22
    Publishing country Spain
    Document type Case Reports ; Research Support, Non-U.S. Gov't
    ZDB-ID 2592481-3
    ISSN 1885-5857 ; 1885-5857
    ISSN (online) 1885-5857
    ISSN 1885-5857
    DOI 10.1016/j.rec.2022.01.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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