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  1. Article ; Online: Efficacy of Tixagevimab-Cilgavimab as Immunoprophylaxis in Patients With Hematologic Cancer.

    Salvini, Marco / Grossi, Paolo Antonio / Cacioppo, Alessandro / Merli, Michele / Pellegrini, Giacomo / Brociner, Marco / Passamonti, Francesco

    JAMA oncology

    2024  Volume 10, Issue 3, Page(s) 405–407

    MeSH term(s) Humans ; Antibodies, Monoclonal ; Hematologic Neoplasms/complications ; Hematologic Neoplasms/drug therapy ; Patients
    Chemical Substances tixagevimab ; cilgavimab (1KUR4BN70F) ; Antibodies, Monoclonal
    Language English
    Publishing date 2024-01-25
    Publishing country United States
    Document type Journal Article
    ISSN 2374-2445
    ISSN (online) 2374-2445
    DOI 10.1001/jamaoncol.2023.6446
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Masticatory Function in Stage IV Periodontitis Patients Treated with Fixed Prosthetic Rehabilitations: A Case Series.

    Merli, Mauro / Aquilanti, Luca / Pagliaro, Umberto / Mariotti, Giorgia / Merli, Marco / Nieri, Michele / Rappelli, Giorgio

    The International journal of periodontics & restorative dentistry

    2023  Volume 44, Issue 1, Page(s) 103–113

    Abstract: The present study assessed the impact of a fixed prosthetic rehabilitation on masticatory function in patients diagnosed with stage IV periodontitis. Eligible participants were adults in need of complex rehabilitation due to masticatory dysfunction. ... ...

    Abstract The present study assessed the impact of a fixed prosthetic rehabilitation on masticatory function in patients diagnosed with stage IV periodontitis. Eligible participants were adults in need of complex rehabilitation due to masticatory dysfunction. Masticatory function was evaluated using the two-colored chewing gum mixing ability test (VOH) at the diagnostic phase (T0), 1 week after delivery of the prosthetic prototype (T1), and 1 week after delivery of the final prosthetic solution (T2). Ten subjects were treated with a fixed prosthesis following periodontal and implant surgery using an individualized, fully digital workflow. Full-mouth plaque and bleeding scores, pocket depth, and clinical attachment level improved significantly. VOH was 0.472 ± 0.168 at T0, 0.358 ± 0.166 at T1, and 0.250 ± 0.123 at T2. A significant improvement in VOH was observed from T0 to T1 (difference: -0.114; 95% CI: -0.199 to -0.029; P = .014) and from T1 to T2 (difference: -0.108; 95% CI: -0.200 to -0.015; P = .027). From T0 to T2, VOH increased by 44.3%. Self-perceived assessment of masticatory function also improved from T0 to T2 (P = .002). The fixed prosthetic rehabilitation in patients with stage IV periodontitis allowed for a significant improvement in objective and subjective measurements of masticatory function.
    MeSH term(s) Adult ; Humans ; Periodontitis ; Mastication ; Dental Prosthesis
    Language English
    Publishing date 2023-08-07
    Publishing country United States
    Document type Journal Article
    ISSN 1945-3388
    ISSN (online) 1945-3388
    DOI 10.11607/prd.6670
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Multiple aspects of the maternal reproductive investment in a polytocous species: What do mothers really control?

    Brogi, Rudy / Chirichella, Roberta / Merli, Enrico / Apollonio, Marco

    Current zoology

    2022  Volume 69, Issue 2, Page(s) 136–142

    Abstract: One of the factors facilitating the expansion and proliferation of wild ... ...

    Abstract One of the factors facilitating the expansion and proliferation of wild boar
    Language English
    Publishing date 2022-05-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2628880-1
    ISSN 1674-5507
    ISSN 1674-5507
    DOI 10.1093/cz/zoac034
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Lateral Sinus Floor Elevation in the Severely Atrophied Maxilla: Concentrated Growth Factors Versus Bone Substitutes. A Controlled Clinical Trial.

    Merli, Mauro / Moscatelli, Marco / Merli, Marco / Mariotti, Giorgia / Pagliaro, Umberto / Nieri, Michele

    The International journal of periodontics & restorative dentistry

    2022  Volume 42, Issue 1, Page(s) 65–72

    Abstract: The present study clinically and radiographically compares the outcome of implants inserted in maxillary sinuses augmented with concentrated growth factors (CGFs) or demineralized bovine bone matrix (DBBM) in a one-stage lateral approach. In 20 patients ... ...

    Abstract The present study clinically and radiographically compares the outcome of implants inserted in maxillary sinuses augmented with concentrated growth factors (CGFs) or demineralized bovine bone matrix (DBBM) in a one-stage lateral approach. In 20 patients with a residual bone height of 1 to 4 mm, lateral sinus floor elevation was performed, using CGFs or DBBM as the sole grafting material, with simultaneous implant placement. Outcome variables were implant and prosthesis failures, complications, subjective satisfaction, and radiographic changes in marginal bone level (MBL) 12 months after surgery. The patients were consecutively recruited: 10 to the CGF group and 10 to the DBBM group. No implant failed in either group at 12 months postsurgery, and there were no complications. There was no statistically significant difference in MBL change between the CGF and DBBM groups (difference of -0.3 mm, favoring the CGF group; 95% confidence interval [CI]: -0.8 to 0.2; P = .18). There was no statistically significant difference in satisfaction (difference of 0.2, favoring the CGF group; 95% CI: -0.2 to 0.6; P = .29). Within the limitations of the present study, the lateral sinus floor elevation performed with the use of CGFs as the sole grafting material showed implant survival rates and marginal bone level changes comparable to DBBM grafting.
    MeSH term(s) Animals ; Bone Substitutes/therapeutic use ; Cattle ; Dental Implantation, Endosseous ; Dental Implants ; Dental Restoration Failure ; Humans ; Maxilla/diagnostic imaging ; Maxilla/surgery ; Maxillary Sinus ; Sinus Floor Augmentation ; Transverse Sinuses ; Treatment Outcome
    Chemical Substances Bone Substitutes ; Dental Implants
    Language English
    Publishing date 2022-01-21
    Publishing country United States
    Document type Controlled Clinical Trial ; Journal Article
    ISSN 1945-3388
    ISSN (online) 1945-3388
    DOI 10.11607/prd.5509
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Meropenem-Vaborbactam for the Treatment of Post-Neurosurgical Meningitis Caused by KPC Producer Klebsiella Pneumoniae: A Case Report and Review of the Literature.

    Rezzonico, Leonardo Francesco / Peracchi, Francesco / Vecchi, Marta / Bassi, Gabriele / Merli, Marco / Bana, Nicholas Brian / Travi, Giovanna / Crippa, Fulvio / Puoti, Massimo

    Antibiotics (Basel, Switzerland)

    2024  Volume 13, Issue 4

    Abstract: Meningitis and ventriculitis, due to carbapenem- ... ...

    Abstract Meningitis and ventriculitis, due to carbapenem-resistant
    Language English
    Publishing date 2024-04-05
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics13040331
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The Multilayer GBR Technique: An Alternative Approach for One-Stage Transmucosal Implant Placement in the Presence of Horizontal Defects. A Case Series.

    Merli, Mauro / Merli, Marco / Pagliaro, Umberto / Fratini, Adriano / Lo Russo, Lucio / Nieri, Michele

    The International journal of periodontics & restorative dentistry

    2022  Volume 42, Issue 4, Page(s) e113–e120

    Abstract: This study presents a one-stage technique for horizontal guided bone regeneration and transmucosal implant placement in the presence of hard and soft tissue defects. The proposed technique uses autologous bone particles, deproteinized bovine bone matrix, ...

    Abstract This study presents a one-stage technique for horizontal guided bone regeneration and transmucosal implant placement in the presence of hard and soft tissue defects. The proposed technique uses autologous bone particles, deproteinized bovine bone matrix, collagen membranes, and concentrated growth factor membranes to create a multilayer barrier and enhance tissue regeneration. Four patients were treated with a total of seven implants. Digital analyses of intraoral scan data taken at baseline and at 6 months postsurgery showed a mean increase in tissue volume of 157.4 mm
    MeSH term(s) Animals ; Bone Matrix/transplantation ; Bone Regeneration ; Cattle ; Collagen/therapeutic use ; Dental Implantation, Endosseous/methods ; Dental Implants ; Guided Tissue Regeneration, Periodontal/methods ; Humans ; Membranes, Artificial ; Wound Healing
    Chemical Substances Dental Implants ; Membranes, Artificial ; Collagen (9007-34-5)
    Language English
    Publishing date 2022-07-12
    Publishing country United States
    Document type Journal Article
    ISSN 1945-3388
    ISSN (online) 1945-3388
    DOI 10.11607/prd.6084
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Use of long-acting cabotegravir + rilpivirine during hemodialysis and solid organ transplantation.

    Rezzonico, Leonardo F / Baldassari, Luca / Peracchi, Francesco / Merli, Marco / Puoti, Massimo / Rossotti, Roberto

    AIDS (London, England)

    2023  Volume 37, Issue 9, Page(s) 1491–1493

    MeSH term(s) Humans ; HIV Infections/drug therapy ; Anti-Retroviral Agents/therapeutic use ; Pyridones/therapeutic use ; Rilpivirine/therapeutic use ; Organ Transplantation ; Renal Dialysis ; Anti-HIV Agents/therapeutic use
    Chemical Substances cabotegravir (HMH0132Z1Q) ; Anti-Retroviral Agents ; Pyridones ; Rilpivirine (FI96A8X663) ; Anti-HIV Agents
    Language English
    Publishing date 2023-07-03
    Publishing country England
    Document type Letter
    ZDB-ID 639076-6
    ISSN 1473-5571 ; 0269-9370 ; 1350-2840
    ISSN (online) 1473-5571
    ISSN 0269-9370 ; 1350-2840
    DOI 10.1097/QAD.0000000000003567
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Use of autogenous bone versus deproteinised bovine bone matrix in one-stage lateral sinus floor elevation in severely atrophied maxillae: A 7-year randomised controlled trial.

    Merli, Mauro / Moscatelli, Marco / Mariotti, Giorgia / Pagliaro, Umberto / Merli, Marco / Nieri, Michele

    International journal of oral implantology (Berlin, Germany)

    2021  Volume 14, Issue 1, Page(s) 101–112

    Abstract: Purpose: To compare 100% deproteinised bovine bone matrix grafts (DBBM, test group) and 100% autogenous bone grafts (AB, control group) for lateral maxillary sinus floor elevation in a blinded, parallel-group, randomised clinical trial.: Materials and ...

    Abstract Purpose: To compare 100% deproteinised bovine bone matrix grafts (DBBM, test group) and 100% autogenous bone grafts (AB, control group) for lateral maxillary sinus floor elevation in a blinded, parallel-group, randomised clinical trial.
    Materials and methods: Patients with 1 to 3 mm of residual bone height were randomised for sinus floor elevation with DBBM or AB grafts and simultaneous implant placement. The outcome variables were implant failure, complications, subjective satisfaction and radiographic peri-implant bone level 7 years after loading.
    Results: A total of 20 patients (27 implants) were randomised to the test group and 20 (32 implants) to the control group. Ten patients from the test group and seven from the control group dropped out. Two implant failures occurred in the test group, whereas none were observed in the control group (P = 0.178). One complication occurred in the test group and two were recorded in the control group (P = 1.000). The radiographic peri-implant crestal bone level was 2.5 ± 1.3 mm in the test group and 0.9 ± 0.9 mm in the control group. The difference was 1.6 mm, favouring the control group (95% confidence interval 0.7-2.6; P = 0.002). The difference in vertical bone height was -0.4 mm, favouring the control group (95% confidence interval -1.9-1.1; P = 0.590). The difference in satisfaction measured using a visual analogue scale 7 years after loading was 0.0 mm (95% confidence interval -1.0-0.0; P = 0.639).
    Conclusions: Differences between treatments were found for crestal bone level, favouring the control group. No differences were observed for the other variables evaluated.
    MeSH term(s) Animals ; Bone Matrix ; Cattle ; Dental Implantation, Endosseous ; Dental Restoration Failure ; Humans ; Maxilla/diagnostic imaging ; Sinus Floor Augmentation ; Transverse Sinuses
    Language English
    Publishing date 2021-05-15
    Publishing country Germany
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 2968002-5
    ISSN 2631-6439 ; 2631-6420
    ISSN (online) 2631-6439
    ISSN 2631-6420
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  9. Article: Role of Transjugular Intrahepatic Portosystemic Shunt in the Liver Transplant Setting.

    Di Cola, Simone / Lapenna, Lucia / Gazda, Jakub / Fonte, Stefano / Cusi, Giulia / Esposito, Samuele / Mattana, Marco / Merli, Manuela

    Journal of clinical medicine

    2024  Volume 13, Issue 2

    Abstract: Liver transplantation is currently the only curative therapy for patients with liver cirrhosis. Not all patients in the natural course of the disease will undergo transplantation, but the majority of them will experience portal hypertension and its ... ...

    Abstract Liver transplantation is currently the only curative therapy for patients with liver cirrhosis. Not all patients in the natural course of the disease will undergo transplantation, but the majority of them will experience portal hypertension and its complications. In addition to medical and endoscopic therapy, a key role in managing these complications is played by the placement of a transjugular intrahepatic portosystemic shunt (TIPS). Some indications for TIPS placement are well-established, and they are expanding and broadening over time. This review aims to describe the role of TIPS in managing patients with liver cirrhosis, in light of liver transplantation. As far as it is known, TIPS placement seems not to affect the surgical aspects of liver transplantation, in terms of intraoperative bleeding rates, postoperative complications, or length of stay in the Intensive Care Unit. However, the placement of a TIPS "towards transplant" can offer advantages in terms of ameliorating a patient's clinical condition at the time of transplantation and improving patient survival. Additionally, the TIPS procedure can help preserve the technical feasibility of the transplant itself. In this context, indications for TIPS placement at an earlier stage are drawing particular attention. However, TIPS insertion in decompensated patients can also lead to serious adverse events. For these reasons, further studies are needed to make reliable recommendations for TIPS in the pre-transplant setting.
    Language English
    Publishing date 2024-01-21
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13020600
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Dietary Strategies in Adult Patients with Eosinophilic Esophagitis: A State-of-the-Art Review.

    Rossi, Carlo Maria / Lenti, Marco Vincenzo / Merli, Stefania / Cena, Hellas / Di Sabatino, Antonio

    Nutrients

    2023  Volume 15, Issue 10

    Abstract: Allergen-free diets are a specific and effective anti-inflammatory therapy for eosinophilic esophagitis. They should be carried out by a multidisciplinary team to reduce side effects and improve adherence. According to recent guidelines and expert ... ...

    Abstract Allergen-free diets are a specific and effective anti-inflammatory therapy for eosinophilic esophagitis. They should be carried out by a multidisciplinary team to reduce side effects and improve adherence. According to recent guidelines and expert opinions, empirical diets with a reduced number of eliminated food categories and a step-up approach are the most encouraged strategy to reduce the number of endoscopies to identify food trigger(s) and maximize clinical results and adherence. Despite the fact that allergy testing-based diets are not recommended at a population level, geographical sensitization patterns may play a role in some patients in specific areas, such as in Southern and Central Europe.
    MeSH term(s) Adult ; Humans ; Allergens ; Diet ; Eosinophilic Esophagitis ; Food ; Food Hypersensitivity
    Chemical Substances Allergens
    Language English
    Publishing date 2023-05-22
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15102409
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