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  1. Article: Biochemical Bone Markers During the Transition Period Are Not Influenced by Parenteral Treatment With a High Dose of Cholecalciferol but Can Predict Milk Fever in Dairy Cows.

    Starič, Jože / Hodnik, Jaka Jakob

    Frontiers in veterinary science

    2021  Volume 7, Page(s) 591324

    Abstract: Despite being studied extensively, there are still many knowledge gaps in milk fever prevention and it is still a prevalent disease. Various interventions have been used in its prevention; however, none has proven to be entirely effective. The study ... ...

    Abstract Despite being studied extensively, there are still many knowledge gaps in milk fever prevention and it is still a prevalent disease. Various interventions have been used in its prevention; however, none has proven to be entirely effective. The study aimed to assess the effectiveness of high dose vitamin D
    Language English
    Publishing date 2021-02-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2834243-4
    ISSN 2297-1769
    ISSN 2297-1769
    DOI 10.3389/fvets.2020.591324
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Biochemical Bone Markers During the Transition Period Are Not Influenced by Parenteral Treatment With a High Dose of Cholecalciferol but Can Predict Milk Fever in Dairy Cows

    Jože Starič / Jaka Jakob Hodnik

    Frontiers in Veterinary Science, Vol

    2021  Volume 7

    Abstract: Despite being studied extensively, there are still many knowledge gaps in milk fever prevention and it is still a prevalent disease. Various interventions have been used in its prevention; however, none has proven to be entirely effective. The study ... ...

    Abstract Despite being studied extensively, there are still many knowledge gaps in milk fever prevention and it is still a prevalent disease. Various interventions have been used in its prevention; however, none has proven to be entirely effective. The study aimed to assess the effectiveness of high dose vitamin D3 parenteral (intramuscularly) administration and the mechanism of its action by studying blood minerals and biochemical bone markers. Further, we assessed the potential of biochemical bone markers, measured in the close-up dry period, as predictors of clinical milk fever after calving. The study was conducted on 56 high yielding, clinically healthy dairy cows, before their 4th or higher lactation. They were divided into three groups based on season (summer and winter) and administration (vitamin D). The winter group was considered as the control group. Cows (n = 13) were parenterally administered a single dose of 10 million IU of vitamin D3 (DUPHAFRAL® D3) ranging between 10 and 2 days before calving (median = 3 days). Each cow was blood sampled once during four sampling period ranges: ~1 month before calving, 10 to 2 days before calving, 12–48 h after calving and 10–20 days after calving. The samples were analyzed for blood minerals, bone specific alkaline phosphatase (bALP) and C-terminal telopeptide of type I collagen (CTx), alkaline phosphatase, and estradiol. Values were compared between samplings and groups. A receiver operating characteristic (ROC) analysis and logistic regression were used to assess the diagnostic accuracy of biochemical bone markers in predicting milk fever. In this study high dose vitamin D3 supplementation did not statistically reduced the incidence of milk fever (milk fever incidences were 15.4, 39.1, and 25% in the vitamin D, winter and summer groups, respectively). A significant effect of vitamin D3 administration on blood minerals or biochemical bone markers was not found at any sampling. We found that the use of biochemical bone markers in the close-up dry period to predict ...
    Keywords cattle ; hypocalcaemia ; estradiol ; bone alkaline phosphatase ; vitamin D3 ; C-terminal telopeptide of type I collagen ; Veterinary medicine ; SF600-1100
    Subject code 630
    Language English
    Publishing date 2021-02-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: The knowledge gap in influence of fundal pressure during delivery on obstetric anal sphincter injury.

    Bukovec, Petra / Šturm Indihar, Blažka / Hodnik, Jaka Jakob / Drusany Starič, Kristina

    European journal of obstetrics, gynecology, and reproductive biology

    2023  Volume 288, Page(s) 231

    MeSH term(s) Female ; Pregnancy ; Humans ; Anal Canal/injuries ; Delivery, Obstetric/adverse effects ; Surveys and Questionnaires ; Fecal Incontinence ; Obstetric Labor Complications ; Risk Factors
    Language English
    Publishing date 2023-07-26
    Publishing country Ireland
    Document type Letter ; Comment
    ZDB-ID 190605-7
    ISSN 1872-7654 ; 0301-2115 ; 0028-2243
    ISSN (online) 1872-7654
    ISSN 0301-2115 ; 0028-2243
    DOI 10.1016/j.ejogrb.2023.07.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The influence of the fundal pressure manoeuvre at delivery on the anal sphincter injury diagnosed with endoanal ultrasonography.

    Bukovec, Petra / Šturm, Blažka / Hodnik, Jaka Jakob / Drusany Starič, Kristina

    European journal of obstetrics, gynecology, and reproductive biology

    2022  Volume 273, Page(s) 65–68

    Abstract: Objectives: The fundal pressure manoeuvre (FPM) is a procedure where the fundus of the uterus is pushed through the abdominal wall by the midwifes and doctors to shorten the terminal phase of the second stage vaginal delivery. Nowadays its use is ... ...

    Abstract Objectives: The fundal pressure manoeuvre (FPM) is a procedure where the fundus of the uterus is pushed through the abdominal wall by the midwifes and doctors to shorten the terminal phase of the second stage vaginal delivery. Nowadays its use is controversial and associated with many adverse effects. The aim of the study was to evaluate benefits and adverse maternal outcomes after FPM. The correlation of the FPM with episiotomy was evaluated. The role of the FPM on pelvic floor dysfunction such as anal incontinence due to anal sphincter injury was assessed.
    Study design: The retrospective study was conducted between 2017 and 2021. The women who came to the postpartum examination to Gynaecology department for various reasons and gave vaginal birth to a singleton were included in the study. The women who had instrumental delivery were excluded. Minimal sample size was calculated with calculator.net and set on 45. Two groups were formed one with fundal pressure and one without, 96 and 90 patients respectively. The maternal, fetal, and obstetric factors that could be associated with the application of FPM were examined. The endoanal ultrasound examination was performed on all women included in the study.
    Results: The study did not show that FPM would lead to a more frequent occurrence of anal sphincter injury (p = 0.73), effect its location (p = 0.77) and depth (p = 0.97), however the test group tended to have longer ruptures compared to control group (p = 0.1). No statistically significant differences in episiotomies between control and test group (p = 0.075) were shown. Endoanal ultrasound showed discrepancy between clinically stated and ultrasonographical diagnoses of anal sphincter injuries. In 61,3% of patients with anal sphincter injury after FPM, reported one of the anal incontinence problems of varying degrees six months after delivery.
    Conclusion: Given that the study proved that FPM is not correlated to the anal sphincter injury it can be used safely. The FPM should be performed carefully and only if necessary to safely finish the labour or in combination with instrumental delivery.
    MeSH term(s) Anal Canal/diagnostic imaging ; Anal Canal/injuries ; Delivery, Obstetric/adverse effects ; Delivery, Obstetric/methods ; Episiotomy ; Fecal Incontinence/diagnostic imaging ; Fecal Incontinence/epidemiology ; Fecal Incontinence/etiology ; Female ; Humans ; Pregnancy ; Retrospective Studies ; Ultrasonography
    Language English
    Publishing date 2022-04-15
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 190605-7
    ISSN 1872-7654 ; 0301-2115 ; 0028-2243
    ISSN (online) 1872-7654
    ISSN 0301-2115 ; 0028-2243
    DOI 10.1016/j.ejogrb.2022.04.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Enzootic Bovine Leukosis: Surveillance Measures and Control Program in the Northern Dobruja Area of Romania Between 2017 and 2020.

    Irimia, Elena / Mincu, Madalina / Pogurschi, Elena Narcisa / Hodnik, Jaka Jakob / Santman-Berends, Inge M G A

    Frontiers in veterinary science

    2021  Volume 8, Page(s) 687287

    Language English
    Publishing date 2021-08-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2834243-4
    ISSN 2297-1769
    ISSN 2297-1769
    DOI 10.3389/fvets.2021.687287
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Coronaviruses in cattle.

    Hodnik, Jaka Jakob / Ježek, Jožica / Starič, Jože

    Tropical animal health and production

    2020  Volume 52, Issue 6, Page(s) 2809–2816

    Abstract: Bovine coronaviruses are spread all over the world. They cause two types of clinical manifestations in cattle either an enteric, calf diarrhoea and winter dysentery in adult cattle, or respiratory in all age groups of cattle. The role of coronaviruses in ...

    Abstract Bovine coronaviruses are spread all over the world. They cause two types of clinical manifestations in cattle either an enteric, calf diarrhoea and winter dysentery in adult cattle, or respiratory in all age groups of cattle. The role of coronaviruses in respiratory infections is still a hot topic of discussion since they have been isolated from sick as well as healthy animals and replication of disease is rarely successful. Bovine coronavirus infection is characterised by high morbidity but low mortality. The laboratory diagnosis is typically based on serological or molecular methods. There is no registered drug for the treatment of virus infections in cattle and we are limited to supportive therapy and preventative measures. The prevention of infection is based on vaccination, biosecurity, management and hygiene. This paper will cover epidemiology, taxonomy, pathogenesis, clinical signs, diagnosis, therapy, economic impact and prevention of coronavirus infections in cattle.
    MeSH term(s) Animals ; Cattle ; Cattle Diseases/diagnosis ; Cattle Diseases/epidemiology ; Cattle Diseases/therapy ; Cattle Diseases/virology ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Coronavirus Infections/therapy ; Coronavirus Infections/veterinary ; Coronavirus, Bovine/classification ; Coronavirus, Bovine/isolation & purification ; Coronavirus, Bovine/physiology ; Diarrhea/veterinary ; Diarrhea/virology ; Enterocolitis, Necrotizing/veterinary ; Enterocolitis, Necrotizing/virology ; Respiratory Tract Infections/veterinary ; Respiratory Tract Infections/virology ; Vaccination/veterinary
    Keywords covid19
    Language English
    Publishing date 2020-07-17
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 603363-5
    ISSN 1573-7438 ; 0049-4747
    ISSN (online) 1573-7438
    ISSN 0049-4747
    DOI 10.1007/s11250-020-02354-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: A review of vitamin D and its importance to the health of dairy cattle.

    Hodnik, Jaka Jakob / Ježek, Jožica / Starič, Jože

    The Journal of dairy research

    2020  Volume 87, Issue S1, Page(s) 84–87

    Abstract: This Research Reflection short review will discuss vitamin D metabolism, its role in nutrition, disease prevention, and welfare of dairy cattle, as well as its toxicity. Vitamin D is an important fat-soluble vitamin. However, some researchers regard it ... ...

    Abstract This Research Reflection short review will discuss vitamin D metabolism, its role in nutrition, disease prevention, and welfare of dairy cattle, as well as its toxicity. Vitamin D is an important fat-soluble vitamin. However, some researchers regard it as a hormone due to its function in the organism. Its role is not limited just to Ca homoeostasis and bone metabolism but is also associated with immunity. In dairy cattle it is known for preventing milk fever. Cows can acquire vitamin D in many ways for example through feed, parenteral injections or through UVB irradiation from the sun or artificial lighting. The vitamin D in feed can either be plant-/ fungi- based ergocalciferol or animal-based cholecalciferol. There is currently only one registered feed vitamin D supplement for cattle in the European Union and it is cholecalciferol. Animals can also synthesize their own vitamin D when 7-dihydrocholesterol in the skin is irradiated with UVB light resulting in cholecalciferol production. Despite its importance, many cattle are deficient in vitamin D due to inadequate supplementation or insufficient sun exposure. In a study performed at the Veterinary Faculty in Slovenia 12 high producing Holstein Friesian cows at a commercial dairy farm were blood tested for vitamin D status for three succeeding months and all but one were vitamin D insufficient in all testings. The cows were not exposed to direct sunlight and the content of vitamin D3 in feed was <400 IU/kg dry matter, which is less than half of the NRC (2001) recommendation. Deficiency can also occur due to diseases affecting the gastrointestinal tract, such as paratuberculosis, which lower the absorptive capacity of the gut. Vitamin D can be toxic if cows are over-supplemented or consume large quantities of plants like Trisetum flavescens, which contain an active form of vitamin D-calcitriol or its glycosides, that are activated by digestion in the rumen.
    MeSH term(s) Animal Feed/analysis ; Animal Welfare ; Animals ; Cattle/physiology ; Cattle Diseases/prevention & control ; Cholecalciferol/administration & dosage ; Dairying ; Dietary Supplements ; European Union ; Female ; Health Status ; Lactation ; Skin/metabolism ; Sunlight ; Vitamin D/administration & dosage ; Vitamin D/physiology ; Vitamin D/toxicity ; Vitamin D Deficiency/veterinary
    Chemical Substances Vitamin D (1406-16-2) ; Cholecalciferol (1C6V77QF41)
    Language English
    Publishing date 2020-07-30
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 242089-2
    ISSN 1469-7629 ; 0022-0299
    ISSN (online) 1469-7629
    ISSN 0022-0299
    DOI 10.1017/S0022029920000424
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Coronaviruses in cattle

    Hodnik, Jaka Jakob / Ježek, Jožica / Starič, Jože

    Tropical animal health and production. 2020 Nov., v. 52, no. 6

    2020  

    Abstract: Bovine coronaviruses are spread all over the world. They cause two types of clinical manifestations in cattle either an enteric, calf diarrhoea and winter dysentery in adult cattle, or respiratory in all age groups of cattle. The role of coronaviruses in ...

    Abstract Bovine coronaviruses are spread all over the world. They cause two types of clinical manifestations in cattle either an enteric, calf diarrhoea and winter dysentery in adult cattle, or respiratory in all age groups of cattle. The role of coronaviruses in respiratory infections is still a hot topic of discussion since they have been isolated from sick as well as healthy animals and replication of disease is rarely successful. Bovine coronavirus infection is characterised by high morbidity but low mortality. The laboratory diagnosis is typically based on serological or molecular methods. There is no registered drug for the treatment of virus infections in cattle and we are limited to supportive therapy and preventative measures. The prevention of infection is based on vaccination, biosecurity, management and hygiene. This paper will cover epidemiology, taxonomy, pathogenesis, clinical signs, diagnosis, therapy, economic impact and prevention of coronavirus infections in cattle.
    Keywords Bovine coronavirus ; Coronavirus infections ; adults ; animal health ; biosecurity ; calves ; drugs ; dysentery ; economic impact ; epidemiology ; hygiene ; laboratory diagnosis ; morbidity ; mortality ; pathogenesis ; taxonomy ; vaccination ; viruses
    Language English
    Dates of publication 2020-11
    Size p. 2809-2816.
    Publishing place Springer Netherlands
    Document type Article
    Note NAL-AP-2-clean ; Review
    ZDB-ID 603363-5
    ISSN 1573-7438 ; 0049-4747
    ISSN (online) 1573-7438
    ISSN 0049-4747
    DOI 10.1007/s11250-020-02354-y
    Database NAL-Catalogue (AGRICOLA)

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  9. Article: Minimal Erythema Dose Determination in Holstein Friesian Cattle.

    Hodnik, Jaka Jakob / Jankovec, Marko / Ježek, Jožica / Krušič, Žiga / Mitterhofer, Stefan / Starič, Jože

    Frontiers in veterinary science

    2021  Volume 8, Page(s) 757452

    Abstract: Cattle on pasture are continuously exposed to solar UV radiation, which has been associated with biological effects such as sunburn, photosensitization, squamous cell carcinoma, and cutaneous vitamin ... ...

    Abstract Cattle on pasture are continuously exposed to solar UV radiation, which has been associated with biological effects such as sunburn, photosensitization, squamous cell carcinoma, and cutaneous vitamin D
    Language English
    Publishing date 2021-11-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2834243-4
    ISSN 2297-1769
    ISSN 2297-1769
    DOI 10.3389/fvets.2021.757452
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Corrigendum: Overview of Slovenian Control Programmes for Selected Cattle Diseases, Listed Under Category C, D or E of the European Animal Health Law.

    Hodnik, Jaka Jakob / Knific, Tanja / Starič, Jože / Toplak, Ivan / Ocepek, Matjaž / Hostnik, Peter / Ježek, Jožica

    Frontiers in veterinary science

    2022  Volume 8, Page(s) 835395

    Abstract: This corrects the article DOI: 10.3389/fvets.2021.674515.]. ...

    Abstract [This corrects the article DOI: 10.3389/fvets.2021.674515.].
    Language English
    Publishing date 2022-01-12
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2834243-4
    ISSN 2297-1769
    ISSN 2297-1769
    DOI 10.3389/fvets.2021.835395
    Database MEDical Literature Analysis and Retrieval System OnLINE

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