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  1. Article: [No title information]

    Bovier, Patrick / Eggimann, Philippe

    Revue medicale suisse

    2020  Volume 16, Issue 695, Page(s) 1123

    Title translation Réponse.
    Language French
    Publishing date 2020-07-16
    Publishing country Switzerland
    Document type Letter ; Comment
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5998: Show issues Location:
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  2. Article: [No title information]

    Bovier, Patrick / Eggimann, Philippe

    Revue medicale suisse

    2020  Volume 16, Issue 692, Page(s) 962

    Title translation Coronella, pour une surveillance efficace du COVID-19.
    MeSH term(s) COVID-19 ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; Epidemiological Monitoring ; Humans ; Pandemics/prevention & control ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; Public Health Surveillance
    Language French
    Publishing date 2020-05-06
    Publishing country Switzerland
    Document type Letter
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
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    Zs.A 5998: Show issues Location:
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  4. Article ; Online: Recent advances with a virosomal hepatitis A vaccine.

    Bovier, Patrick A

    Expert opinion on biological therapy

    2008  Volume 8, Issue 8, Page(s) 1177–1185

    Abstract: Background: Epaxal, a virosomal vaccine against hepatitis A virus (HAV) infection, has been in use for nearly 15 years, especially among at-risk adults. Recent studies have shown that it is also a potent vaccine for children.: Objective: To summarise ...

    Abstract Background: Epaxal, a virosomal vaccine against hepatitis A virus (HAV) infection, has been in use for nearly 15 years, especially among at-risk adults. Recent studies have shown that it is also a potent vaccine for children.
    Objective: To summarise recent advances of Epaxal Junior (0.25 ml, paediatric formulation).
    Methods: Published papers reporting results on the virosomal HAV vaccine were abstracted and reviewed.
    Results/conclusion: In a comparative randomised trial, the paediatric dose was found to be highly immunogenic and non-inferior to the standard dose with respect to seroprotection rates. The concomitant administration of virosomal HAV vaccine with routine childhood vaccines was investigated in another trial. The virosomal HAV vaccine did not interact with the antibody response of routine childhood vaccines which in turn did not reduce the antibody response to HAV. In countries that recommend immunisation against hepatitis A, this virosomal vaccine is an excellent candidate with few side effects at the site of injection.
    MeSH term(s) Child ; Child, Preschool ; Health Services Needs and Demand ; Hepatitis A/prevention & control ; Hepatitis A Antibodies/biosynthesis ; Hepatitis A Vaccines/administration & dosage ; Hepatitis A Vaccines/adverse effects ; Hepatitis A Vaccines/immunology ; Humans ; Immunization, Secondary ; Infant ; Virosomes
    Chemical Substances Hepatitis A Antibodies ; Hepatitis A Vaccines ; Virosomes ; epaxal berna
    Language English
    Publishing date 2008-04-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 2052501-1
    ISSN 1744-7682 ; 1471-2598
    ISSN (online) 1744-7682
    ISSN 1471-2598
    DOI 10.1517/14712598.8.8.1177
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    Zs.A 6094: Show issues Location:
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  5. Article: Explosion du tourisme médical: des voyageurs d'un nouveau type?

    Bovier, Patrick A

    Revue medicale suisse

    2008  Volume 4, Issue 157, Page(s) 1196, 1198–201

    Abstract: In an era of globalisation, an increasing number of patients are seeking medical care abroad, for a fraction of the price in their home country The reasons are numerous. Some countries face an increasing demand, either because of inappropriate health ... ...

    Title translation Medical tourism: a new kind of traveler?.
    Abstract In an era of globalisation, an increasing number of patients are seeking medical care abroad, for a fraction of the price in their home country The reasons are numerous. Some countries face an increasing demand, either because of inappropriate health insurance coverage (e.g. United States) or long waiting lists (e.g. United-Kingdom, Canada). In parallel, medical care facilities and infrastructures of many countries of Asia and latin America offer now high quality care, if not better, than their European or North American counterparts. In theses conditions, more and more patients decide now to travel abroad for cardiovascular and orthopedic surgery that they cannot readily have in their home country. In Switzerland, this phenomenon is still marginal but changes could occur in a near future.
    MeSH term(s) Health Services Accessibility ; Humans ; Patient Acceptance of Health Care ; Travel
    Language French
    Publishing date 2008-05-14
    Publishing country Switzerland
    Document type English Abstract ; Journal Article
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Epaxal: a virosomal vaccine to prevent hepatitis A infection.

    Bovier, Patrick A

    Expert review of vaccines

    2008  Volume 7, Issue 8, Page(s) 1141–1150

    Abstract: Over the last few decades, different types of inactivated hepatitis A virus (HAV) vaccines have been developed: several aluminum-adjuvanted vaccines and an aluminum-free, virosome-formulated vaccine. Both types of vaccines are whole-virus preparations ... ...

    Abstract Over the last few decades, different types of inactivated hepatitis A virus (HAV) vaccines have been developed: several aluminum-adjuvanted vaccines and an aluminum-free, virosome-formulated vaccine. Both types of vaccines are whole-virus preparations that are produced by growth of HAV strains in human diploid cell cultures and are subsequently inactivated with formaldehyde. This review summarizes all published papers on a virosome-formulated vaccine, Epaxal, based on formalin inactivated HAV (strain RG-SB) adsorbed to the surface of special liposomes (virosomes), that replace aluminum hydroxide as the adjuvant principle. A single injection of virosomal HAV vaccine is well tolerated and highly immunogenic, with 88-97% of seroprotection 2 weeks after a first dose. HAV virosomal vaccine can be administered concomitantly with other vaccines, without inducing antigenic competition. Direct comparison with aluminum-adsorbed vaccine has shown that the immunogenicity was similar, but fewer local reactions were reported with Epaxal. Recent studies in children have demonstrated that Epaxal Junior is also an excellent HAV vaccine for mass vaccination programs.
    MeSH term(s) Adolescent ; Adult ; Child ; Child, Preschool ; Hepatitis A/prevention & control ; Hepatitis A Vaccines/adverse effects ; Hepatitis A Vaccines/immunology ; Hepatitis A virus/immunology ; Humans ; Infant ; Vaccines, Virosome/immunology
    Chemical Substances Hepatitis A Vaccines ; Vaccines, Virosome ; epaxal berna
    Language English
    Publishing date 2008-10
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2181284-6
    ISSN 1744-8395 ; 1476-0584
    ISSN (online) 1744-8395
    ISSN 1476-0584
    DOI 10.1586/14760584.7.8.1141
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6077: Show issues Location:
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  7. Article ; Online: What are patients' expectations about the organization of their primary care physicians' practices?

    Sebo, Paul / Herrmann, François R / Bovier, Patrick / Haller, Dagmar M

    BMC health services research

    2015  Volume 15, Page(s) 328

    Abstract: Background: To our knowledge no study has at the same time assessed patients' satisfaction and their expectations concerning the organizational and contextual aspects of health care provided by their primary care physician (PCP). Assessing these aspects ...

    Abstract Background: To our knowledge no study has at the same time assessed patients' satisfaction and their expectations concerning the organizational and contextual aspects of health care provided by their primary care physician (PCP). Assessing these aspects is important to inform future primary healthcare service planning. Our objective was thus to document patients' satisfaction with and expectations from their PCP, in terms of availability and organization of their practices, and to assess whether these indicators varied across age groups and type of practice (solo, duo, group).
    Methods: Cross-sectional study based on the answers to questionnaires completed by patients consulting their PCP in Geneva, Switzerland. A random sample of PCPs was asked to recruit consecutively between 50 and 100 patients coming to the practice for a scheduled medical consultation. The patients were asked to complete an anonymous questionnaire centered on their satisfaction levels and expectations towards their PCP.
    Results: One thousand six hundred thirty-seven patients agreed to participate (participation rate: 97%, women: 63%, mean age: 54 years). Patient satisfaction was high for all the items, except for the availability of the doctor by phone and for the waiting time in the waiting room. The satisfaction rate increased with age and was higher for small practices. In relation to patients' expectations from their doctor, older patients and patients visiting larger practices tended to be more demanding.
    Conclusions: Patients are generally highly satisfied with their PCP. They have a wide range of expectations which should be taken into account when considering potential improvements.
    MeSH term(s) Adult ; Aged ; Cross-Sectional Studies ; Female ; Humans ; Male ; Middle Aged ; Organizations ; Patient Satisfaction ; Physicians, Primary Care ; Professional Practice/organization & administration ; Referral and Consultation ; Surveys and Questionnaires ; Switzerland ; Young Adult
    Language English
    Publishing date 2015-08-14
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1472-6963
    ISSN (online) 1472-6963
    DOI 10.1186/s12913-015-0985-y
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  8. Article ; Online: Stress from uncertainty from graduation to retirement--a population-based study of Swiss physicians.

    Bovier, Patrick A / Perneger, Thomas V

    Journal of general internal medicine

    2007  Volume 22, Issue 5, Page(s) 632–638

    Abstract: Background: Uncertainty shapes many decisions made by physicians everyday. Uncertainty and physicians' inability to handle it may result in substandard care and unexplained variations in patterns of care.: Objective: To describe socio-demographic and ...

    Abstract Background: Uncertainty shapes many decisions made by physicians everyday. Uncertainty and physicians' inability to handle it may result in substandard care and unexplained variations in patterns of care.
    Objective: To describe socio-demographic and professional characteristics of reactions to uncertainty among physicians from all specialties, including physicians in training.
    Design: Cross-sectional postal survey.
    Participant: All physicians practicing in Geneva, Switzerland (n = 1,994).
    Measurement: Reaction to medical care uncertainty was measured with the Anxiety Due to Uncertainty and Concern About Bad Outcomes scales. The questionnaire also included items about professional characteristics and work-related satisfaction scales.
    Results: After the first mailing and two reminders, 1,184 physicians responded to the survey. In univariate analysis, women, junior physicians, surgical specialists, generalist physicians, and physicians with lower workloads had higher scores in both scales. In multivariate models, sex, medical specialty, and workload remained significantly associated with both scales, whereas clinical experience remained associated only with concern about bad outcomes. Higher levels of anxiety due to uncertainty were associated with lower scores of work-related satisfaction, while higher levels of concern about bad outcomes were associated with lower satisfaction scores for patient care, personal rewards, professional relations, and general satisfaction, but not for work-related burden or satisfaction with income-prestige. The negative effect of anxiety due to uncertainty on work-related satisfaction was more important for physicians in training.
    Conclusion: Physicians' reactions to uncertainty in medical care were associated with several dimensions of work-related satisfaction. Physicians in training experienced the greatest impact of anxiety due to uncertainty on their work-related satisfaction. Incorporating strategies to deal with uncertainty into residency training may be useful.
    MeSH term(s) Adult ; Cross-Sectional Studies ; Female ; Humans ; Job Satisfaction ; Male ; Middle Aged ; Physicians/psychology ; Physicians/trends ; Retirement/psychology ; Retirement/trends ; Stress, Psychological/epidemiology ; Switzerland ; Uncertainty
    Language English
    Publishing date 2007-05
    Publishing country United States
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639008-0
    ISSN 1525-1497 ; 0884-8734
    ISSN (online) 1525-1497
    ISSN 0884-8734
    DOI 10.1007/s11606-007-0159-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2205: Show issues Location:
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  9. Article: Pain management in a medical walk-in clinic: link between recommended processes and pain relief.

    Perron, Noelle Junod / Bovier, Patrick

    International journal for quality in health care : journal of the International Society for Quality in Health Care

    2007  Volume 19, Issue 5, Page(s) 274–280

    Abstract: Background: While most recommended pain management practices have been developed for hospitalised patients, little is known about their relevance for ambulatory patients presenting with acute pain.: Objective: In this study, we explored the ... ...

    Abstract Background: While most recommended pain management practices have been developed for hospitalised patients, little is known about their relevance for ambulatory patients presenting with acute pain.
    Objective: In this study, we explored the relationship between patients' reported use of recommended pain management practices and pain relief in outpatients.
    Method: 703 adult patients who presented with pain at the medical walk-in clinic of the University Hospitals of Geneva, Switzerland, were included in a mailed cross-sectional survey. They completed a self-administered questionnaire with specific items on self reports of pain and pain management processes.
    Main outcome measures: Patient's self reports on pain and pain management processes.
    Results: Of the 703 patients presenting with pain, 40% reported complete pain relief after their visit at the medical walk-in clinic. After adjustment for age, sex, origin, general health and intensity of pain, patients' self-report of complete pain relief was associated with availability of medical doctors (OR = 5.6; 95% CI 2.1-14.7 for excellent vs. poor availability), availability of nurses (OR = 2.6; 95% CI 1.2-6.0 for excellent vs. poor availability), waiting < 10 min for pain medication (OR = 4.6; 95% CI 2.2-9.8), regular assessment of pain (OR = 1.7; 95% CI 1.02-2.7) and having received information about pain and its management (OR = 3.0; 95% CI 1.8-4.9).
    Conclusions: Self-reported pain relief was associated with more frequent use of recommended pain management processes. These recommendations initially developed for hospitalized patients should also be encouraged for ambulatory care patients.
    MeSH term(s) Acute Disease ; Adult ; Aged ; Cross-Sectional Studies ; Female ; Guideline Adherence ; Health Status ; Hospitals, Teaching ; Humans ; Male ; Middle Aged ; Multivariate Analysis ; Outpatient Clinics, Hospital/organization & administration ; Outpatient Clinics, Hospital/standards ; Outpatient Clinics, Hospital/statistics & numerical data ; Pain/psychology ; Pain Management ; Pain Measurement ; Patient Satisfaction ; Quality Assurance, Health Care ; Surveys and Questionnaires ; Switzerland ; Treatment Outcome
    Language English
    Publishing date 2007-10
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1194150-9
    ISSN 1353-4505
    ISSN 1353-4505
    DOI 10.1093/intqhc/mzm032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3052: Show issues Location:
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  10. Article ; Online: Accuracy of doctors' anthropometric measurements in general practice.

    Sebo, Paul / Haller, Dagmar / Pechère-Bertschi, Antoinette / Bovier, Patrick / Herrmann, François

    Swiss medical weekly

    2015  Volume 145, Page(s) w14115

    Abstract: Purpose: There is increasing pressure on general practitioners (GPs) to identify patients with abdominal obesity in order to reduce the life-threatening consequences of this condition in the population. We aimed to confirm previous findings on the ... ...

    Abstract Purpose: There is increasing pressure on general practitioners (GPs) to identify patients with abdominal obesity in order to reduce the life-threatening consequences of this condition in the population. We aimed to confirm previous findings on the inaccuracy of anthropometric measurements performed by GPs in an academic primary care clinic and to assess the effect of theoretical training to improve the quality of these measurements.
    Methods: This cross-sectional study involved 26 GPs from private practices in Geneva, Switzerland. They were asked to measure weight, height, waist and hip circumference on ten volunteers within their practice. Two trained research assistants repeated the measurementss after the GPs ("gold standard"). The GPs were then randomised to receive information detailing the correct method for taking measurements (intervention, 14 doctors) or simple information about obesity (control, 12 doctors). Measurements were repeated a few weeks later. Measurement error was computed by comparing the GPs' values with the average value of two measurements taken in turn by the research assistants, and agreement was examined by Bland-Altman plots. The GPs' skills were assessed through auto-questionnaire and direct observation.
    Results: All measurements except height were prone to measurement error, the least affected being weight (and therefore body mass index [BMI]). Following training, measurement errors were slightly less prominent in the intervention group. GPs' skills in measuring waist and hip circumference were frequently assessed as inadequate, but showed improvement after training.
    Conclusions: Without proper training, priority should be given to using classical anthropometric measurements (i.e. weight, height and BMI determination) in daily practice.
    MeSH term(s) Adult ; Anthropometry/methods ; Body Height ; Body Mass Index ; Body Weight ; Body Weights and Measures/standards ; Cross-Sectional Studies ; Female ; General Practice/standards ; Health Knowledge, Attitudes, Practice ; Humans ; Male ; Middle Aged ; Obesity/diagnosis ; Reproducibility of Results ; Surveys and Questionnaires ; Switzerland ; Waist Circumference
    Language English
    Publishing date 2015
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2036179-8
    ISSN 1424-3997 ; 1424-7860
    ISSN (online) 1424-3997
    ISSN 1424-7860
    DOI 10.4414/smw.2015.14115
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