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  1. Book ; Online ; E-Book: Essentials of hypertension

    Fuchs, Flávio Danni

    the 120/80 paradigm

    2018  

    Author's details Flávio Danni Fuchs
    Keywords Medicine ; Cardiology ; Nephrology ; Neurology ; Primary care (Medicine)
    Subject code 616.12
    Language English
    Size 1 Online-Ressource (xiii, 151 Seiten), Illustrationen, Diagramme
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019558516
    ISBN 978-3-319-63272-8 ; 9783319632711 ; 3-319-63272-8 ; 331963271X
    DOI 10.1007/978-3-319-63272-8
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Is it Time to Retire the Diagnosis "Hypertensive Emergency"?

    Fuchs, Flávio Danni / Gus, Miguel / Gonçalves, Sandro Cadaval / Fuchs, Sandra Costa

    Journal of the American Heart Association

    2023  Volume 12, Issue 3, Page(s) e028494

    MeSH term(s) Humans ; Hypertension ; Antihypertensive Agents/therapeutic use ; Retirement ; Emergencies
    Chemical Substances Antihypertensive Agents
    Language English
    Publishing date 2023-01-25
    Publishing country England
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 2653953-6
    ISSN 2047-9980 ; 2047-9980
    ISSN (online) 2047-9980
    ISSN 2047-9980
    DOI 10.1161/JAHA.122.028494
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The Effect of Alcohol on Blood Pressure and Hypertension.

    Fuchs, Flávio Danni / Fuchs, Sandra Costa

    Current hypertension reports

    2021  Volume 23, Issue 10, Page(s) 42

    Abstract: Purpose: To examine the acute and chronic effects of alcohol on blood pressure (BP) and the incidence of hypertension. We discuss the most current understanding of the mechanisms underlining these effects and their associations with the putative ... ...

    Abstract Purpose: To examine the acute and chronic effects of alcohol on blood pressure (BP) and the incidence of hypertension. We discuss the most current understanding of the mechanisms underlining these effects and their associations with the putative cardioprotective effects of consumption of low-to-moderate amounts of alcoholic beverages.
    Recent findings: A recent meta-analysis confirmed findings of experimental studies, demonstrating an acute biphasic effect of ethanol on BP, decreasing up to 12 h of ingestion and increasing after that. This effect is mediated by vagal inhibition and sympathetic activation. A meta-analysis found that chronic consumption of alcoholic beverages was associated with a high incidence of hypertension in men and women; it also found that, in women, the risk begins at moderate alcohol consumption. The risks of alcohol consumption are higher in Blacks than in Asians or Caucasians. The mechanism underlying the chronic effects of alcohol on BP, and particularly the differential effect on Blacks, is still unknown. Short-term trials showed that alcohol withdrawal promotes BP reduction; however, the long-term effectiveness of interventions that aim to lower BP through the restriction of alcohol consumption has not been demonstrated. The harmful effects of alcohol on BP do not support the putative cardioprotective effect of low-to-moderate consumption of alcoholic beverages. The absence of a tangible mechanism of protection, and the possibility that this beneficial effect is biased by socioeconomic and other characteristics of drinkers and abstainers, calls into question the hypothesis that consuming low amounts of alcoholic beverages improves cardiovascular health. The evidence from investigations with various designs converge regarding the acute biphasic effect of ethanol on BP and the risk of chronic consumption on the incidence of hypertension, particularly for Blacks. These effects do not support the putative cardioprotective effect of consumption of low-to-moderate amounts of alcoholic beverages. Mechanisms of chronic BP increase and the demonstration of long-term benefits of reducing alcohol intake as a means to treat hypertension remain open questions.
    MeSH term(s) Alcoholism ; Blood Pressure ; Ethanol ; Female ; Humans ; Hypertension ; Male ; Substance Withdrawal Syndrome
    Chemical Substances Ethanol (3K9958V90M)
    Language English
    Publishing date 2021-11-11
    Publishing country United States
    Document type Journal Article ; Meta-Analysis ; Review
    ZDB-ID 2057367-4
    ISSN 1534-3111 ; 1522-6417
    ISSN (online) 1534-3111
    ISSN 1522-6417
    DOI 10.1007/s11906-021-01160-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5522: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: HIPERTENSÃO ARTERIAL

    Flávio Danni Fuchs / Miguel Gus

    Clinical and Biomedical Research, Vol 24, Iss

    NOVOS PARADIGMAS PARA DIAGNÓSTICO E TRATAMENTO

    2020  Volume 1

    Abstract: Hipertensão arterial é fator de risco cardiovascular freqüente, muitas vezes despercebido e mal controlado. Evidências recentes de estudos de coorte reforçam a idéia de que é fortemente desejável manter valores muito baixos de pressão arterial ao correr ... ...

    Abstract Hipertensão arterial é fator de risco cardiovascular freqüente, muitas vezes despercebido e mal controlado. Evidências recentes de estudos de coorte reforçam a idéia de que é fortemente desejável manter valores muito baixos de pressão arterial ao correr da vida, o que pode ser conseguido com a adoção de estilo de vida saudável. Essas evidências, em conjunto com o resultado de ensaios clínicos, demonstram que, em indivíduos de alto risco, o tratamento medicamentoso antihipertensivo está indicado mesmo em presença de pressão arterial normal. A primeira opção antihipertensiva para a maioria dos pacientes deve recair em diuréticos em baixa dose, como demonstra a análise conjunta de inúmeros ensaios clínicos e os resultados do maior deles, o estudo Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). Unitermos: Hipertensão; eventos cardiovasculares; prevenção
    Keywords Hipertensão ; eventos cardiovasculares ; prevenção ; Medicine ; R
    Language English
    Publishing date 2020-03-01T00:00:00Z
    Publisher Hospital de Clinicas de Porto Alegre
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: The role of angiotensin receptor blockers in CVD risk management.

    Bottino, Leonardo Grabinski / Fuchs, Flávio Danni

    Expert review of cardiovascular therapy

    2020  Volume 18, Issue 4, Page(s) 181–185

    Abstract: ... ...

    Abstract Introduction
    MeSH term(s) Angiotensin Receptor Antagonists/administration & dosage ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/prevention & control ; Humans ; Hypertension/drug therapy ; Randomized Controlled Trials as Topic ; Reproducibility of Results ; Risk Management ; Suicide/statistics & numerical data
    Chemical Substances Angiotensin Receptor Antagonists
    Language English
    Publishing date 2020-04-06
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2192343-7
    ISSN 1744-8344 ; 1477-9072
    ISSN (online) 1744-8344
    ISSN 1477-9072
    DOI 10.1080/14779072.2020.1750369
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6107: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Response to the letter to the editor entitled 'Angiotensin-II receptor blockers or angiotensin converting enzyme inhibitors for the treatment of hypertension amid COVID-19 pandemic'.

    Bottino, Leonardo Grabinski / Fuchs, Flávio Danni

    Expert review of cardiovascular therapy

    2020  Volume 19, Issue 2, Page(s) 189–190

    MeSH term(s) Angiotensin Receptor Antagonists ; Angiotensin-Converting Enzyme Inhibitors/therapeutic use ; Angiotensins ; Antihypertensive Agents/therapeutic use ; COVID-19 ; Humans ; Hypertension/drug therapy ; Hypertension/epidemiology ; Pandemics ; SARS-CoV-2
    Chemical Substances Angiotensin Receptor Antagonists ; Angiotensin-Converting Enzyme Inhibitors ; Angiotensins ; Antihypertensive Agents
    Language English
    Publishing date 2020-12-15
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2192343-7
    ISSN 1744-8344 ; 1477-9072
    ISSN (online) 1744-8344
    ISSN 1477-9072
    DOI 10.1080/14779072.2021.1862548
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6107: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  7. Article ; Online: Association between preoperative blood pressure and outcomes in cardiac surgery: results of a prospectively planned cohort study.

    Molinari Veloso da Silveira, Lucas / Costa Fuchs, Sandra / Brendel Blum, Gabriela / Grabinski Bottino, Leonardo / Danni Fuchs, Flávio

    The Journal of cardiovascular surgery

    2023  Volume 64, Issue 5, Page(s) 548–554

    Abstract: Background: It is unknown whether unwitnessed BP (UBP) measurement or ambulatory BP (ABP) monitoring improves the prediction of adverse events estimated by risk scores. We intended to study associations between preoperative BP measured through these two ...

    Abstract Background: It is unknown whether unwitnessed BP (UBP) measurement or ambulatory BP (ABP) monitoring improves the prediction of adverse events estimated by risk scores. We intended to study associations between preoperative BP measured through these two methods and the incidence of adverse outcomes in patients undergoing cardiac surgery.
    Methods: We included a cohort of 167 patients undergoing elective or urgent cardiac surgeries. Preoperative BP was measured by UBP and 24-hour ABP. Primary outcome was the combination of mortality from any cause, nonfatal myocardial infarction, nonfatal stroke, new hospital admission, and dialysis occurring within 30 days after surgery. The associations between preoperative BP and surgical outcomes were tested using the Chi-square test and Analysis of Variance. A generalized linear model with a logistic link function and a robust estimator was used to adjust for the EuroScore-II risk estimation.
    Results: The incidence of the primary outcome increased in parallel with the quartiles of the 24-hour ABP in participants submitted to CABG: 10% in the first quartile, 13% in the second, 37% in the third, and 53% in the fourth quartile (P for trend<0.01). Quartiles of overnight ABP were also significantly associated with postoperative complications in patients undergoing CABG (P=0.04). The risks in CABG patients were independent of the EuroScore-II. There was no association between BP and outcomes in patients submitted to other surgeries.
    Conclusions: High preoperative BP measured by ABP monitoring is a risk factor for postoperative complications in patients submitted to CABG.
    Language English
    Publishing date 2023-05-31
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 80143-4
    ISSN 1827-191X ; 0021-9509
    ISSN (online) 1827-191X
    ISSN 0021-9509
    DOI 10.23736/S0021-9509.23.12581-X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 469: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: NÚMERO TEMÁTICO - CARDIOLOGIA

    Flávio Danni Fuchs / Jorge Pinto Ribeiro

    Clinical and Biomedical Research, Vol 25, Iss

    2020  Volume 3

    Keywords Medicine ; R
    Language English
    Publishing date 2020-03-01T00:00:00Z
    Publisher Hospital de Clinicas de Porto Alegre
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: O ENSINO DE FARMACOLOGIA MÉDICA DIRECIONADO À REALIDADE

    Flávio Danni Fuchs / Lenita Wannmacher / Marcelo Victor

    Revista Brasileira de Educação Médica, Vol 12, Iss 2, Pp 52-

    EXEMPLO DE UMA EXPERIÊNCIA PIONEIRA

    2020  Volume 54

    Abstract: Resumo Os autores preconizam o ensino de Farmacologia Médica voltado à realidade de prescrição em nosso meio, relatando experiências pedagógicas fundamentadas na solução de problemas. Dentre elas, que incluem solução de casos clínico-farmacológicos ... ...

    Abstract Resumo Os autores preconizam o ensino de Farmacologia Médica voltado à realidade de prescrição em nosso meio, relatando experiências pedagógicas fundamentadas na solução de problemas. Dentre elas, que incluem solução de casos clínico-farmacológicos simulados, seminários de análise crítica da literatura original em Farmacologia aplicada e aulas expositivas, salienta-se a atividade prática da disciplina: preenchimento de fichas de avaliação da prescrição medicamentosa de pacientes internados no hospital-escola. No presente trabalho descrevem-se a metodologia dessa atividade e os resultados obtidos.
    Keywords Education (General) ; L7-991 ; Medicine (General) ; R5-920
    Language Portuguese
    Publishing date 2020-08-01T00:00:00Z
    Publisher Associção Brasileira de Educação Médica
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Renin-Angiotensin-Aldosterone System Inhibitors in COVID-19

    Filipe Ferrari / Vítor Magnus Martins / Flávio Danni Fuchs / Ricardo Stein

    Clinics, Vol

    A Review

    2021  Volume 76

    Abstract: Among the multiple uncertainties surrounding the novel coronavirus disease (COVID-19) pandemic, a research letter published in The Lancet implicated drugs that antagonize the renin-angiotensin-aldosterone system (RAAS) in an unfavorable prognosis of ... ...

    Abstract Among the multiple uncertainties surrounding the novel coronavirus disease (COVID-19) pandemic, a research letter published in The Lancet implicated drugs that antagonize the renin-angiotensin-aldosterone system (RAAS) in an unfavorable prognosis of COVID-19. This report prompted investigations to identify mechanisms by which blocking angiotensin-converting enzyme 2 (ACE2) could lead to serious consequences in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The possible association between RAAS inhibitors use and unfavorable prognosis in this disease may have been biased by the presence of underlying cardiovascular diseases. As the number of COVID-19 cases has increased worldwide, it has now become possible to investigate the association between RAAS inhibitors and unfavorable prognosis in larger cohorts. Observational studies and one randomized clinical trial failed to identify any consistent association between the use of these drugs and unfavorable prognosis in COVID-19. In view of the accumulated clinical evidence, several scientific societies recommend that treatment with RAAS inhibitors should not be discontinued in patients diagnosed with COVID-19 (unless contraindicated). This recommendation should be followed by clinicians and patients.
    Keywords Pandemic ; Infection ; SARS-CoV-2 ; Hypertension ; Heart Failure ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2021-04-01T00:00:00Z
    Publisher Elsevier España
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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