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  1. Article: Anton, Balint, Charles Bonnet, and the Others: The ABC of Cerebral Visual Syndromes (A Historical Guide and an Update).

    Kertesz, Andrew

    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques

    2023  Volume 51, Issue 2, Page(s) 300–304

    Abstract: Cerebral visual impairments have been of great interest to neurologists, ophthalmologists, and neuroscientists. Complicated or partial varieties related to cortical blindness are discussed in this review. They are a fascinating alphabet of eponymic ... ...

    Abstract Cerebral visual impairments have been of great interest to neurologists, ophthalmologists, and neuroscientists. Complicated or partial varieties related to cortical blindness are discussed in this review. They are a fascinating alphabet of eponymic clinical syndromes, bordering neurology, ophthalmology, and even psychiatry. Recent functional imaging and experimental studies have contributed further knowledge of cognitive visual organization in addition to the classical lesion evidence.
    MeSH term(s) Humans ; Neurology ; Vision Disorders ; Blindness, Cortical ; Brain Diseases/complications ; Syndrome ; Hallucinations/etiology
    Language English
    Publishing date 2023-06-30
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 197622-9
    ISSN 0317-1671
    ISSN 0317-1671
    DOI 10.1017/cjn.2023.246
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1203: Show issues Location:
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  2. Article ; Online: Estimating the loss of economic predictability from aggregating firm-level production networks.

    Diem, Christian / Borsos, András / Reisch, Tobias / Kertész, János / Thurner, Stefan

    PNAS nexus

    2024  Volume 3, Issue 3, Page(s) pgae064

    Abstract: To estimate the reaction of economies to political interventions or external disturbances, input-output (IO) tables-constructed by aggregating data into industrial sectors-are extensively used. However, economic growth, robustness, and resilience ... ...

    Abstract To estimate the reaction of economies to political interventions or external disturbances, input-output (IO) tables-constructed by aggregating data into industrial sectors-are extensively used. However, economic growth, robustness, and resilience crucially depend on the detailed structure of nonaggregated firm-level production networks (FPNs). Due to nonavailability of data, little is known about how much aggregated sector-based and detailed firm-level-based model predictions differ. Using a nearly complete nationwide FPN, containing 243,399 Hungarian firms with 1,104,141 supplier-buyer relations, we self-consistently compare production losses on the aggregated industry-level production network (IPN) and the granular FPN. For this, we model the propagation of shocks of the same size on both, the IPN and FPN, where the latter captures relevant heterogeneities within industries. In a COVID-19 inspired scenario, we model the shock based on detailed firm-level data during the early pandemic. We find that using IPNs instead of FPNs leads to an underestimation of economic losses of up to 37%, demonstrating a natural limitation of industry-level IO models in predicting economic outcomes. We ascribe the large discrepancy to the significant heterogeneity of firms within industries: we find that firms within one sector only sell 23.5% to and buy 19.3% from the same industries on average, emphasizing the strong limitations of industrial sectors for representing the firms they include. Similar error levels are expected when estimating economic growth, CO
    Language English
    Publishing date 2024-02-17
    Publishing country England
    Document type Journal Article
    ISSN 2752-6542
    ISSN (online) 2752-6542
    DOI 10.1093/pnasnexus/pgae064
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  3. Article ; Online: Bacterial interactions with the mycelium of the cultivated edible mushrooms Agaricus bisporus and Pleurotus ostreatus.

    Shamugam, Shivaghami / Kertesz, Michael A

    Journal of applied microbiology

    2023  Volume 134, Issue 1

    Abstract: The cultivated edible mushrooms Agaricus bisporus and Pleurotus ostreatus are valuable food crops and an important source of human nutrition. Agaricus bisporus is the dominant cultivated species in the western hemisphere and in Australia, while in Asian ... ...

    Abstract The cultivated edible mushrooms Agaricus bisporus and Pleurotus ostreatus are valuable food crops and an important source of human nutrition. Agaricus bisporus is the dominant cultivated species in the western hemisphere and in Australia, while in Asian countries P. ostreatus is more prevalent. These two mushroom species are grown on fermented-pasteurized substrates, and bacteria and fungi play an important role in converting feedstocks into a selective medium for the mushroom mycelium. The mushrooms are usually introduced to the substrate as grain spawn, and the actively growing hyphae form a range of direct interactions with the diverse bacterial community in the substrate. Of these interactions, the most well studied is the removal of inhibitory volatile C8 compounds and ethylene by pseudomonads, which promotes mycelium growth and stimulates primordia formation of both A. bisporus and P. ostreatus. Bacterial biomass in the substrate is a significant nutrition source for the A. bisporus mycelium, both directly through bacteriolytic enzymes produced by A. bisporus, and indirectly through the action of extracellular bacterial enzymes, but this is less well studied for P. ostreatus. Apart from their role as a food source for the growing mycelium, bacteria also form extensive interactions with the mycelium of A. bisporus and P. ostreatus, by means other than those of the removal of inhibitory compounds. Although several of these interactions have been observed to promote mycelial growth, the proposed mechanisms of growth promotion by specific bacterial strains remain largely uncertain, and at times conflicting. Bacterial interactions also elicit varying growth-inhibitory responses from A. bisporus and P. ostreatus. This review explores characterized interactions involving bacteria and A. bisporus, and to a lesser degree P.ostreatus, and whilst doing so identifies existing research gaps and emphasizes directions for future work.
    MeSH term(s) Humans ; Pleurotus/chemistry ; Agaricus/chemistry ; Bacteria ; Mycelium
    Language English
    Publishing date 2023-01-10
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 1358023-1
    ISSN 1365-2672 ; 1364-5072
    ISSN (online) 1365-2672
    ISSN 1364-5072
    DOI 10.1093/jambio/lxac018
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    Zs.A 259: Show issues Location:
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  4. Article ; Online: Exact p-value calculation for XCorr scoring of high-resolution MS/MS data.

    Bhimani, Kishankumar / Peresadina, Arina / Vozniuk, Dmitrii / Kertész-Farkas, Attila

    Proteomics

    2023  Volume 24, Issue 5, Page(s) e2300145

    Abstract: Exact p-value (XPV)-based methods for dot product-like score functions-such as the XCorr score implemented in Tide, SEQUEST, Comet or shared peak count-based scoring in MSGF+ and ASPV-provide a fairly good calibration for peptide-spectrum-match (PSM) ... ...

    Abstract Exact p-value (XPV)-based methods for dot product-like score functions-such as the XCorr score implemented in Tide, SEQUEST, Comet or shared peak count-based scoring in MSGF+ and ASPV-provide a fairly good calibration for peptide-spectrum-match (PSM) scoring in database searching-based MS/MS spectrum data identification. Unfortunately, standard XPV methods, in practice, cannot handle high-resolution fragmentation data produced by state-of-the-art mass spectrometers because having smaller bins increases the number of fragment matches that are assigned to incorrect bins and scored improperly. In this article, we present an extension of the XPV method, called the high-resolution exact p-value (HR-XPV) method, which can be used to calibrate PSM scores of high-resolution MS/MS spectra obtained with dot product-like scoring such as the XCorr. The HR-XPV carries remainder masses throughout the fragmentation, allowing them to greatly increase the number of fragments that are properly assigned to the correct bin and, thus, taking advantage of high-resolution data. Using four mass spectrometry data sets, our experimental results demonstrate that HR-XPV produces well-calibrated scores, which in turn results in more trusted spectrum annotations at any false discovery rate level.
    MeSH term(s) Algorithms ; Tandem Mass Spectrometry/methods ; Software ; Peptides/chemistry ; Calibration ; Databases, Protein
    Chemical Substances Peptides
    Language English
    Publishing date 2023-09-19
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2032093-0
    ISSN 1615-9861 ; 1615-9853
    ISSN (online) 1615-9861
    ISSN 1615-9853
    DOI 10.1002/pmic.202300145
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  5. Book ; Online: Zur Frage der Förderung der Textilindustrie Deutschlands

    Kertész, A

    2018  

    Keywords Textilpolitik ; Deutschland <bis 1945>
    Language German
    Dates of publication 2018-1918
    Size 1 Online-Ressource (58 Seiten 4")
    Publisher ZBW
    Publishing place Kiel ; Hamburg
    Document type Book ; Online
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  6. Article ; Online: Nitrogen balance and supply in Australasian mushroom composts.

    Noble, Ralph / Thai, Meghann / Kertesz, Michael A

    Applied microbiology and biotechnology

    2024  Volume 108, Issue 1, Page(s) 151

    Abstract: Mushrooms are an important source of protein in the human diet. They are increasingly viewed as a sustainable meat replacement in an era of growing populations, with button mushrooms (Agaricus bisporus) the most popular and economically important ... ...

    Abstract Mushrooms are an important source of protein in the human diet. They are increasingly viewed as a sustainable meat replacement in an era of growing populations, with button mushrooms (Agaricus bisporus) the most popular and economically important mushroom in Europe, Australia and North America. Button mushrooms are cultivated on a defined, straw-derived compost, and the nitrogen (N) required to grow these high-protein foods is provided mainly by the addition of poultry manure and horse manure. Using the correct balance of carbon (C) and N sources to produce mushroom compost is critically important in achieving maximum mushroom yields. Changes in the amount and form of N added, the rate and timing of N addition and the other compost components used can dramatically change the proportion of added N recovered in the mushroom caps, the yield and quality of the mushrooms and the loss of N as ammonia and nitrogen oxide gases during composting. This review examines how N supply for mushroom production can be optimised by the use of a broad range of inorganic and organic N sources for mushroom composting, together with the use of recycled compost leachate, gypsum and protein-rich supplements. Integrating this knowledge into our current molecular understanding of mushroom compost biology will provide a pathway for the development of sustainable solutions in mushroom production that will contribute strongly to the circular economy. KEY POINTS: • Nitrogen for production of mushroom compost can be provided as a much wider range of organic feedstocks or inorganic compounds than currently used • Most of the nitrogen used in production of mushroom compost is not recovered as protein in the mushroom crop • The sustainability of mushroom cropping would be increased through alternative nitrogen management during composting and cropping.
    MeSH term(s) Animals ; Horses ; Humans ; Composting ; Manure ; Nitrogen/metabolism ; Ammonia ; Poultry ; Agaricus ; Soil
    Chemical Substances Manure ; Nitrogen (N762921K75) ; Ammonia (7664-41-7) ; Soil
    Language English
    Publishing date 2024-01-19
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 392453-1
    ISSN 1432-0614 ; 0171-1741 ; 0175-7598
    ISSN (online) 1432-0614
    ISSN 0171-1741 ; 0175-7598
    DOI 10.1007/s00253-023-12933-2
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    Zs.A 2229: Show issues Location:
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  7. Article ; Online: Progress in Primary Progressive Aphasia: A Review.

    Kertesz, Andrew / Finger, Elizabeth / Munoz, David G

    Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology

    2024  Volume 37, Issue 1, Page(s) 3–12

    Abstract: We present a review of the definition, classification, and epidemiology of primary progressive aphasia (PPA); an update of the taxonomy of the clinical syndrome of PPA; and recent advances in the neuroanatomy, pathology, and genetics of PPA, as well as ... ...

    Abstract We present a review of the definition, classification, and epidemiology of primary progressive aphasia (PPA); an update of the taxonomy of the clinical syndrome of PPA; and recent advances in the neuroanatomy, pathology, and genetics of PPA, as well as the search for biomarkers and treatment. PPA studies that have contributed to concepts of language organization and disease propagation in neurodegeneration are also reviewed. In addition, the issues of heterogeneity versus the relationships of the clinical phenotypes and their relationship to biological, pathological, and genetic advances are discussed, as is PPA's relationship to other conditions such as frontotemporal dementia, corticobasal degeneration, progressive supranuclear palsy, Pick disease, and amyotrophic lateral sclerosis. Arguments are presented in favor of considering these conditions as one entity versus many.
    MeSH term(s) Humans ; Frontotemporal Dementia/diagnosis ; Frontotemporal Dementia/genetics ; Supranuclear Palsy, Progressive/genetics ; Supranuclear Palsy, Progressive/pathology ; Syndrome ; Aphasia, Primary Progressive
    Language English
    Publishing date 2024-03-01
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 2108112-8
    ISSN 1543-3641 ; 1543-3633
    ISSN (online) 1543-3641
    ISSN 1543-3633
    DOI 10.1097/WNN.0000000000000365
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  8. Book ; Online: Die Textilindustrie sämtlicher Staaten

    Kertész, Adolf

    Entwicklung, Erzeugung, Absatzverhältnisse : nach den statistischen Unterlagen der einzelnen Staaten für die Baumwoll-, Seiden-, Leinen-, Jute- und Konfektionsindustrie

    2018  

    Title variant Die Textilindustrie Deutschlands im Welthandel
    Author's details von Adolf Kertesz
    Language German
    Dates of publication 2018-1917
    Size 1 Online-Ressource (XXVI, 741 Seiten)
    Document type Book ; Online
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  9. Article ; Online: Tailor: A Nonparametric and Rapid Score Calibration Method for Database Search-Based Peptide Identification in Shotgun Proteomics.

    Sulimov, Pavel / Kertész-Farkas, Attila

    Journal of proteome research

    2020  Volume 19, Issue 4, Page(s) 1481–1490

    Abstract: Peptide-spectrum-match (PSM) scores used in database searching are calibrated to spectrum- or spectrum-peptide-specific null distributions. Some calibration methods rely on specific assumptions and use analytical models (e.g., binomial distributions), ... ...

    Abstract Peptide-spectrum-match (PSM) scores used in database searching are calibrated to spectrum- or spectrum-peptide-specific null distributions. Some calibration methods rely on specific assumptions and use analytical models (e.g., binomial distributions), whereas other methods utilize exact empirical null distributions. The former may be inaccurate because of unjustified assumptions, while the latter are accurate, albeit computationally exhaustive. Here, we introduce a novel, nonparametric, heuristic PSM score calibration method, called Tailor, which calibrates PSM scores by dividing them with the top 100-quantile of the empirical, spectrum-specific null distributions (i.e., the score with an associated
    MeSH term(s) Algorithms ; Calibration ; Databases, Protein ; Peptides ; Proteomics
    Chemical Substances Peptides
    Language English
    Publishing date 2020-03-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2078618-9
    ISSN 1535-3907 ; 1535-3893
    ISSN (online) 1535-3907
    ISSN 1535-3893
    DOI 10.1021/acs.jproteome.9b00736
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  10. Article ; Online: Early Diagnosis of Frontotemporal Dementia.

    Kertesz, Andrew

    Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology

    2018  Volume 31, Issue 3, Page(s) 168–169

    Language English
    Publishing date 2018-09-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2108112-8
    ISSN 1543-3641 ; 1543-3633
    ISSN (online) 1543-3641
    ISSN 1543-3633
    DOI 10.1097/WNN.0000000000000163
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