LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 248

Search options

  1. Article ; Online: Japan's medical workforce crisis: Nagoya university's new policy significantly reducing physician compensation for education & research.

    Kaneda, Yudai / Ozaki, Akihiko / Kaneda, Uiri / Kosaka, Makoto / Tanimoto, Tetsuya

    QJM : monthly journal of the Association of Physicians

    2024  

    Language English
    Publishing date 2024-01-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 1199985-8
    ISSN 1460-2393 ; 0033-5622 ; 1460-2725
    ISSN (online) 1460-2393
    ISSN 0033-5622 ; 1460-2725
    DOI 10.1093/qjmed/hcae018
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.131: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article: Mirtazapine Monotherapy for Antipsychotics-refractory Psychosis in a Patient with Very-late-onset Schizophrenia-like Psychosis: A Case Report.

    Ueno, Kanji / Ishitobi, Makoto / Kosaka, Hirotaka / Ichijo, Kei / Nagase, Yukihiro

    Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology

    2023  Volume 22, Issue 2, Page(s) 387–389

    Abstract: Very-late-onset schizophrenia-like psychosis (VLOSLP) is a condition in which psychotic symptoms emerge after the age of 60 years. Given its heterogeneous nature, VLOSLP remains a diagnostic and therapeutic dilemma. Here, we report a case of a 68-year- ... ...

    Abstract Very-late-onset schizophrenia-like psychosis (VLOSLP) is a condition in which psychotic symptoms emerge after the age of 60 years. Given its heterogeneous nature, VLOSLP remains a diagnostic and therapeutic dilemma. Here, we report a case of a 68-year-old patient with psychosis refractory to antipsychotics who was successfully treated with mirtazapine monotherapy. This case suggests that mirtazapine monotherapy may be effective for the treatment of patients with antipsychotic- refractory VLOSLP.
    Language English
    Publishing date 2023-09-25
    Publishing country Korea (South)
    Document type Case Reports
    ZDB-ID 2211550-X
    ISSN 1738-1088
    ISSN 1738-1088
    DOI 10.9758/cpn.23.1103
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6227: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Improved method for preparation and purification of recombinant α-synuclein: high-mannose-type free N-glycan prepared from an edible bean (Vigna angulari, Azuki bean) inhibits α-synuclein aggregation.

    Kosaka, Shota / Katsube, Makoto / Maeda, Megumi / Kimura, Yoshinobu

    Bioscience, biotechnology, and biochemistry

    2022  Volume 86, Issue 6, Page(s) 770–774

    Abstract: Parkinson's disease is characterized by the accumulation of amyloid, which consists of α-synuclein (α-Syn). To screen compounds with amyloid aggregation inhibitory activity, an effective method for the preparation of α-Syn is a prerequisite. We ... ...

    Abstract Parkinson's disease is characterized by the accumulation of amyloid, which consists of α-synuclein (α-Syn). To screen compounds with amyloid aggregation inhibitory activity, an effective method for the preparation of α-Syn is a prerequisite. We established a simpler method for α-Syn preparation using freeze-thaw treatment of transformed Escherichia coli. Furthermore, we found that the high-mannose type free N-glycans could prevent α-Syn aggregation.
    MeSH term(s) Amyloid ; Mannose ; Polysaccharides ; Vigna ; alpha-Synuclein
    Chemical Substances Amyloid ; Polysaccharides ; alpha-Synuclein ; Mannose (PHA4727WTP)
    Language English
    Publishing date 2022-04-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 1106450-x
    ISSN 1347-6947 ; 0916-8451
    ISSN (online) 1347-6947
    ISSN 0916-8451
    DOI 10.1093/bbb/zbac040
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4647: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article: Practical Utility of a Clinical Pathway for Older Patients with Aspiration Pneumonia: A Single-Center Retrospective Observational Study.

    Araki, Taisuke / Yamazaki, Yoshitaka / Kimoto, Masanobu / Goto, Norihiko / Ikuyama, Yuichi / Takahashi, Yuko / Kosaka, Makoto

    Journal of clinical medicine

    2023  Volume 13, Issue 1

    Abstract: ... ...

    Abstract Introduction
    Language English
    Publishing date 2023-12-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13010230
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article: [A Case of Advanced Lung Adenocarcinoma in an Elderly Patient Who Maintained Responsiveness after Discontinuation of Immune Checkpoint Inhibitors].

    Suganuma, Akira / Sakaguchi, Koji / Kimoto, Masanobu / Kosaka, Makoto / Yamazaki, Yoshitaka

    Gan to kagaku ryoho. Cancer & chemotherapy

    2023  Volume 50, Issue 11, Page(s) 1231–1233

    Abstract: An 81-year-old woman was admitted to our hospital because of an abnormal opacity on the chest radiograph. She was diagnosed with cT3N3M1a, Stage ⅣA left lower lung lobe adenocarcinoma, and the PD-L1(22C3)expression was high (tumor proportion score[TPS]: ... ...

    Abstract An 81-year-old woman was admitted to our hospital because of an abnormal opacity on the chest radiograph. She was diagnosed with cT3N3M1a, Stage ⅣA left lower lung lobe adenocarcinoma, and the PD-L1(22C3)expression was high (tumor proportion score[TPS]: 100%). She was administered with pembrolizumab monotherapy because her performance status(PS)was PS 1. After 4 courses, she had a partial response(PR), but her treatment had to be discontinued because of cutaneous adverse effects. After 6 months, the tumor regrew, and atezolizumab monotherapy was provided. Another cutaneous adverse event occurred, and treatment was discontinued again. However, a complete response(CR)was maintained for approximately 2 years and 6 months after discontinuation of treatments.
    MeSH term(s) Humans ; Female ; Aged ; Aged, 80 and over ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Lung Neoplasms/drug therapy ; Lung Neoplasms/pathology ; Immune Checkpoint Inhibitors/therapeutic use ; Antineoplastic Agents, Immunological/adverse effects ; Adenocarcinoma of Lung/drug therapy ; B7-H1 Antigen
    Chemical Substances Immune Checkpoint Inhibitors ; Antineoplastic Agents, Immunological ; B7-H1 Antigen
    Language Japanese
    Publishing date 2023-12-06
    Publishing country Japan
    Document type Case Reports ; English Abstract ; Journal Article
    ZDB-ID 604842-0
    ISSN 0385-0684
    ISSN 0385-0684
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 2573: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: What Is the Optimal Treatment for Vulnerable Older Women With Ovarian Cancer?

    Kosaka, Makoto / Mizutani, Tomonori / Ishiki, Hiroto

    JAMA oncology

    2021  Volume 7, Issue 11, Page(s) 1725–1726

    MeSH term(s) Aged ; Carcinoma, Ovarian Epithelial ; Female ; Humans ; Ovarian Neoplasms/therapy
    Language English
    Publishing date 2021-10-06
    Publishing country United States
    Document type Letter ; Comment
    ISSN 2374-2445
    ISSN (online) 2374-2445
    DOI 10.1001/jamaoncol.2021.4125
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Article ; Online: Unresolved questions regarding the promise of the TPEx regimen.

    Kosaka, Makoto / Honma, Yoshitaka / Ishiki, Hiroto

    The Lancet. Oncology

    2021  Volume 22, Issue 6, Page(s) e227

    MeSH term(s) Cetuximab ; Cisplatin ; Docetaxel ; Fluorouracil ; Humans ; Platinum
    Chemical Substances Docetaxel (15H5577CQD) ; Platinum (49DFR088MY) ; Cetuximab (PQX0D8J21J) ; Cisplatin (Q20Q21Q62J) ; Fluorouracil (U3P01618RT)
    Language English
    Publishing date 2021-06-04
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2049730-1
    ISSN 1474-5488 ; 1470-2045
    ISSN (online) 1474-5488
    ISSN 1470-2045
    DOI 10.1016/S1470-2045(21)00246-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 5696: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 460: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Sulfur assimilation using gaseous carbonyl sulfide by the soil fungus

    Iizuka, Ryuka / Hattori, Shohei / Kosaka, Yusuke / Masaki, Yoshihito / Kawano, Yusuke / Ohtsu, Iwao / Hibbett, David / Katayama, Yoko / Yoshida, Makoto

    Applied and environmental microbiology

    2024  Volume 90, Issue 2, Page(s) e0201523

    Abstract: Fungi have the capacity to assimilate a diverse range of both inorganic and organic sulfur compounds. It has been recognized that all sulfur sources taken up by fungi are in soluble forms. In this study, we present evidence that fungi can utilize gaseous ...

    Abstract Fungi have the capacity to assimilate a diverse range of both inorganic and organic sulfur compounds. It has been recognized that all sulfur sources taken up by fungi are in soluble forms. In this study, we present evidence that fungi can utilize gaseous carbonyl sulfide (COS) for the assimilation of a sulfur compound. We found that the filamentous fungus
    MeSH term(s) Gases ; Carbon Dioxide ; Soil ; Phylogeny ; Sulfur Compounds ; Sulfur/metabolism ; Hypocreales/genetics ; Hypocreales/metabolism ; Hydrolases/metabolism ; Sulfates ; Trichoderma/genetics ; Trichoderma/metabolism ; Sulfur Oxides
    Chemical Substances carbonyl sulfide (871UI0ET21) ; Gases ; Carbon Dioxide (142M471B3J) ; Soil ; Sulfur Compounds ; Sulfur (70FD1KFU70) ; Hydrolases (EC 3.-) ; Sulfates ; Sulfur Oxides
    Language English
    Publishing date 2024-02-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 223011-2
    ISSN 1098-5336 ; 0099-2240
    ISSN (online) 1098-5336
    ISSN 0099-2240
    DOI 10.1128/aem.02015-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 201: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Characteristics of Vulnerable Foreigners in Need of Emergency Care Support in Japan: A Case Study of Thai Nationals from 2004 to 2020.

    Supakul, Sopak / Yoshida, Makoto / Kosaka, Makoto / Murayama, Anju / Tani, Yuta / Bhandari, Divya / Ozaki, Akihiko / Tanimoto, Tetsuya

    Journal of immigrant and minority health

    2023  

    Abstract: In Japan, a considerable number of foreigners encounter challenges in accessing appropriate healthcare services due to the lack of insurance coverage. However, the absence of a public database on these individuals makes it difficult to assess their ... ...

    Abstract In Japan, a considerable number of foreigners encounter challenges in accessing appropriate healthcare services due to the lack of insurance coverage. However, the absence of a public database on these individuals makes it difficult to assess their health problems and healthcare access status. This study aims to investigate the characteristics of vulnerable Thai patients in Japan and to shed light on the specific challenges they face within Japan's healthcare system. A retrospective analysis was conducted using records of patients who required emergency healthcare support from the Royal Thai Embassy in Tokyo between 2004 and 2020. Descriptive statistical analyses were performed to examine the general characteristics, insurance status, and diseases of the patients. Additionally, patients were classified as either prolonged residents or brief residents based on their duration of stay in Japan until hospital admission (1 year or more or less than 1 year). A total of 74 patients were identified, with the majority (91.9%) lacking insurance coverage. Notably, there was an increase in the number of brief residents, including tourists, during the 2010s. Prolonged residents were more likely to experience chronic diseases, whereas brief residents were more prone to sustaining injuries. The patient records from the Thai Embassy consistently highlight the urgent requirement for emergency healthcare support within this population. However, the existing policies in Japan fall short in adequately addressing the healthcare access needs of this vulnerable population. Therefore, it is crucial to provide additional support and interventions to enhance their healthcare access.
    Language English
    Publishing date 2023-11-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2220162-2
    ISSN 1557-1920 ; 1557-1912
    ISSN (online) 1557-1920
    ISSN 1557-1912
    DOI 10.1007/s10903-023-01566-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article: Difficulty in continuing home care after informal caregiver was exposed to the COVID-19: A case report.

    Sakamoto, Ryo / Yoshida, Makoto / Bhandari, Divya / Miyatake, Hirotomo / Kosaka, Makoto / Tanimoto, Tetsuya / Kami, Masahiro / Ozaki, Akihiko

    Clinical case reports

    2022  Volume 10, Issue 7, Page(s) e05804

    Abstract: Home care can present many challenges without management. During COVID-19 pandemic, when an informal caregiver becomes infected and had to isolate themselves, finding another caregiver becomes extremely challenging. For terminally ill patients, who ... ...

    Abstract Home care can present many challenges without management. During COVID-19 pandemic, when an informal caregiver becomes infected and had to isolate themselves, finding another caregiver becomes extremely challenging. For terminally ill patients, who relies on other for even minor tasks, interruption of care could pose severe negative consequences.
    Language English
    Publishing date 2022-07-18
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.5804
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top