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Article: Bovine Aortic Arch, A High-Risk Variant.

Shaban, Mohammed / Budhathoki, Pravash / Lee, Somin / Bhatt, Tanushree / Rodriguez Guerra, Miguel A / Zaw, May

2022 Volume 14, Issue 5, Page(s) e25456

Abstract: The bovine aortic arch is a vascular variant related to an increased incidence of vascular and neurological complications. It should be ruled out in patients with vague neurological symptoms without a clear etiology. Our case is of a 72-year-old female ... ...

Abstract	The bovine aortic arch is a vascular variant related to an increased incidence of vascular and neurological complications. It should be ruled out in patients with vague neurological symptoms without a clear etiology. Our case is of a 72-year-old female patient who presented with a syncopal episode; the workup incidentally showed the aortic arch bovine variant with evidence of ischemic white matter disease more than expected for age. After reviewing the related literature, we suggest that this aortic variant is likely an independent risk factor for multiple vascular complications. A close follow-up is essential, and screening should be considered for symptomatic family members.
Language	English
Publishing date	2022-05-29
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.25456
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Diagnostic Dilemma of Widespread Vesiculobullous Lesions: A Case Report.

Khadka, Nisha / Shakya, Subij / Khatiwada, Dikshya / Budhathoki, Pravash / Bhattarai, Tulsi Ram

JNMA; journal of the Nepal Medical Association

2022 Volume 60, Issue 245, Page(s) 86–89

Abstract: Stevens-Johnson syndrome and toxic epidermal necrolysis represent a spectrum of severe mucocutaneous reactions, while Acute Cutaneous Lupus Erythematosus is a variant of Systemic Lupus Erythematosus. Both are rare conditions, with significant morbidity ... ...

Abstract	Stevens-Johnson syndrome and toxic epidermal necrolysis represent a spectrum of severe mucocutaneous reactions, while Acute Cutaneous Lupus Erythematosus is a variant of Systemic Lupus Erythematosus. Both are rare conditions, with significant morbidity and mortality; often indistinguishable clinically and pose a diagnostic dilemma for the clinician. We hereby present a unique case of a 17 years old female who presented with widespread vesiculobullous lesions with peeling, desquamation, and crusting of the skin surface, non-scarring alopecia, oral and nasal ulcers, as well as two episodes of generalized tonic-clonic seizures. The patient had a history of intake of itraconazole tablets for a week, 25 days before the disease manifestation.
MeSH term(s)	Acute Disease ; Adolescent ; Female ; Humans ; Lupus Erythematosus, Cutaneous/complications ; Lupus Erythematosus, Cutaneous/diagnosis ; Lupus Erythematosus, Cutaneous/pathology ; Lupus Erythematosus, Systemic/complications ; Lupus Erythematosus, Systemic/diagnosis ; Stevens-Johnson Syndrome/diagnosis ; Stevens-Johnson Syndrome/etiology
Language	English
Publishing date	2022-01-15
Publishing country	Nepal
Document type	Case Reports ; Journal Article
ZDB-ID	2209910-4
ISSN	1815-672X ; 0028-2715
ISSN (online)	1815-672X
ISSN	0028-2715
DOI	10.31729/jnma.7118
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Epidemiology of Road Traffic Accidents in Nepal from 2009/10 to 2019/20: A 10 Year Study.

Atreya, Alok / Shrestha, Dhan Bahadur / Budhathoki, Pravash / Nepal, Samata

Journal of Nepal Health Research Council

2021 Volume 19, Issue 2, Page(s) 343–348

Abstract: Background: Road traffic accidents are the leading cause of deaths worldwide among children and young adults aged between 5 to 29 years. The risk of road traffic accident-related death is higher in low-income countries. Thus, we aim to evaluate the ... ...

Abstract	Background: Road traffic accidents are the leading cause of deaths worldwide among children and young adults aged between 5 to 29 years. The risk of road traffic accident-related death is higher in low-income countries. Thus, we aim to evaluate the epidemiology of road traffic accidents in Nepal during the fiscal years from 2009/10 to 2019/20. Methods: This study is a secondary data analysis of the published police records publicly available on the official webpage of Nepal Police. A study was carried out after written permission from Nepal Police. The data obtained were analysed using Microsoft Excel-13. Results: Analysing available data about reported road traffic accidents events showed an increasing trend in road traffic accidents from the fiscal years 2011/12 till 2019/20, with a steeper increase in the number of road traffic accidents in fiscal years 2017/18 and 2019/20. In fiscal years 2009/10, 11,747 vehicles collided; which rose to 25,788 in the fiscal years 2019/20. More cases of road traffic accidents were reported to occur from 12 noon-6 pm in a day. Among reported road traffic accidents commonest predispositions behind road traffic accidents was the negligence of driver followed by over speed. Among those individuals who died due to road traffic accidents, most of them were male. Conclusions: We found an increasing trend of road traffic accidents, vehicle collisions, and injuries in Nepal over the past ten years especially among two-wheelers and four-wheelers like the car, bus, and autorickshaw.
MeSH term(s)	Accidents, Traffic ; Adolescent ; Adult ; Child ; Child, Preschool ; Cluster Analysis ; Humans ; Male ; Nepal/epidemiology ; Poverty ; Young Adult
Language	English
Publishing date	2021-09-06
Publishing country	Nepal
Document type	Journal Article
ZDB-ID	2551251-1
ISSN	1999-6217 ; 1999-6217
ISSN (online)	1999-6217
ISSN	1999-6217
DOI	10.33314/jnhrc.v19i2.3432
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: A Case of Severe Epstein-Barr Virus-Associated Hemophagocytic Lymphohistiocytosis Successfully Treated With High Dose Steroids and Ganciclovir.

Budhathoki, Pravash / Qureshi, Zaheer A / Shah, Anish / Khanal, Sneha / Ghazanfar, Haider / Hanif, Ahmad

Cureus

2022 Volume 14, Issue 6, Page(s) e25952

Abstract: Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening hematological disorder characterized by immune dysregulation with multiple organ involvement and carries a poor prognosis. The occurrence of HLH can be familial or sporadic, which is ... ...

Abstract	Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening hematological disorder characterized by immune dysregulation with multiple organ involvement and carries a poor prognosis. The occurrence of HLH can be familial or sporadic, which is triggered by causes like infection or malignancy. This case report is about a 47-year-old male who presented to the hospital with a fever, chills, night sweats, and unintentional weight loss. He was found to have severely elevated ferritin, and computed tomography showed cirrhosis, a normal sized spleen, and retroperitoneal lymphadenopathy. He underwent an extensive battery of tests to identify the etiology. Meanwhile, he had recurrent fevers with worsening transaminitis and septic shock, requiring admission to the ICU. Blood tests for Epstein-Barr virus (EBV) deoxyribonucleic acid (DNA) and immunoglobulin G (IgG) were positive. Due to high suspicion of HLH, he was started on intravenous methylprednisone 1000 mg daily for three days with clinical improvement. A bone marrow biopsy showed hemophagocytosis and he was diagnosed with EBV-associated HLH. He was continued on steroids with oral prednisone and continued to clinically improve. He was later tapered off steroids over the course of five months. HLH is a rapidly progressive and fatal condition that requires prompt treatment, and thus a high index of suspicion is needed to make a timely diagnosis.
Language	English
Publishing date	2022-06-15
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.25952
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Team-Based Learning Among Health Care Professionals: A Systematic Review.

Joshi, Tilak / Budhathoki, Pravash / Adhikari, Anurag / Poudel, Ayusha / Raut, Sumit / Shrestha, Dhan B

Cureus

2022 Volume 14, Issue 1, Page(s) e21252

Abstract: Introduced in the 1970s to meet the academic needs of a growing number of students with relatively stagnant faculty, team-based learning (TBL) has revolutionized the modern classroom structure. Contrary to the traditional didactic model where the teacher ...

Abstract	Introduced in the 1970s to meet the academic needs of a growing number of students with relatively stagnant faculty, team-based learning (TBL) has revolutionized the modern classroom structure. Contrary to the traditional didactic model where the teacher assumes the central role and students are passive listeners, TBL participants are actively involved in the learning process. Teachers act as facilitators while the TBL participants work in groups to solve problems through engagement with their peers. The objective of the article is to conduct a systematic review on team-based learning using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline. The studies were searched in databases like PubMed®, Scopus®, Embase®, and PubMed Central® using appropriate keywords. Two authors screened the papers, and a third author resolved the conflicts. This was followed by a bibliographic review based on the references of the selected study and bias assessment using the Joanna Briggs Institute (JBI) critical appraisal tool. The team-based learning model is increasingly being used by different institutions globally. TBL and traditional lecture-based teaching outcomes revealed that TBL participants performed better in academic, clinical, and communication domains. In addition, TBL enhanced learners' engagement, collaborative spirit, and satisfaction. Our study results are similar to the prior meta-analysis and systematic review. Nevertheless, this systematic review remains more comprehensive, up-to-date, and inclusive thus far. Team-based learning is a pragmatic and superior approach to learning among health care professionals. It has resulted in better academic, clinical, and communication outcomes. This finding spans all the medical and allied professions studied in this systematic review.
Language	English
Publishing date	2022-01-14
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.21252
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Repeat Cesarean Section among Pregnant Women in a Tertiary Center of Nepal: A Descriptive Cross-sectional Study.

Regmi, Dharma Raj / Dangal, Ganesh / Silwal, Ashmita / Shrestha, Dhan Bahadur / Oli, Prakash Raj / Budhathoki, Pravash

JNMA; journal of the Nepal Medical Association

2022 Volume 60, Issue 245, Page(s) 6–11

Abstract: Introduction: Cesarean Section is the most common obstetrics surgery done for both maternal and fetal indications. There is a rising trend of cesarean section rates which is associated with increased maternal morbidities. This study aims to find out the ...

Abstract	Introduction: Cesarean Section is the most common obstetrics surgery done for both maternal and fetal indications. There is a rising trend of cesarean section rates which is associated with increased maternal morbidities. This study aims to find out the prevalence of repeat Cesarean Section among women with previous cesarean sections done in a tertiary centre. Methods: This was a descriptive cross-sectional study conducted in a tertiary care hospital of Nepal from August 2020 to January 2021. Pregnant women with previous Cesarean Section status without other pelvic surgery and medical comorbidities were included and data were collected regarding intraoperative findings. Ethical approval was taken from the Institutional Review Committee (Reference Number: 14). A convenience sampling technique was used. Data were analysed using Statistical Package for the Social Sciences version 22. Point estimate at 95% Confidence Interval was calculated, with frequency and percentage. Results: Out of 1315 patients undergoing Cesarean Section, the prevalence of Repeat Cesarean Section was found to be 184 (13.99%) (12.11-15.86 at 95% Confidence Interval). Conclusions: The prevalence of Repeat Cesarean Cection from our study was similar to other studies done in similar settings. Repeat Cesarean Cection confers peri-operative morbidities which adversely affect postoperative recovery. Repeat Cesarean Cection continues to contribute to morbidity over subsequent pregnancies and serious maternal morbidity.
MeSH term(s)	Cesarean Section ; Cesarean Section, Repeat ; Cross-Sectional Studies ; Female ; Humans ; Nepal/epidemiology ; Pregnancy ; Pregnant Women ; Tertiary Care Centers
Language	English
Publishing date	2022-01-15
Publishing country	Nepal
Document type	Journal Article
ZDB-ID	2209910-4
ISSN	1815-672X ; 0028-2715
ISSN (online)	1815-672X
ISSN	0028-2715
DOI	10.31729/jnma.6597
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Ophthalmoparesis and Bilateral Ptosis as a Rare Manifestation of Todd's Phenomenon: Case Report and Review.

Qureshi, Zaheer A / Shrestha, Elina / Budhathoki, Pravash / Ghazanfar, Haider / Altaf, Faryal / Dhallu, Manjeet

Cureus

2022 Volume 14, Issue 6, Page(s) e26108

Abstract: Todd's paresis or phenomenon (TP) is a focal weakness in a part of the body after a seizure. Seizure is an abrupt change in behavior caused by the cerebral cortex's electrical hyper-synchronization of neuronal networks. After the seizure, there is ... ...

Abstract	Todd's paresis or phenomenon (TP) is a focal weakness in a part of the body after a seizure. Seizure is an abrupt change in behavior caused by the cerebral cortex's electrical hyper-synchronization of neuronal networks. After the seizure, there is usually a transition period from the ictal state to the pre-seizure baseline level of awareness and function, referred to as the postictal period. Postictal symptoms include many systems, including sensory, motor, and psychosis. This phenomenon is named after Robert Bentley Todd, who first described it. Todd's paresis can be confused with other conditions, most commonly a stroke. Postictal ocular manifestation may be accompanied by aphasia or hemiplegia, but isolated gaze palsy is rarely reported. We are reporting a rare and first known isolated ophthalmoparesis and ptosis as postictal findings with no structural abnormalities present in imaging studies and complete resolution over three weeks on its own as an atypical postictal phenomenon. Patients with an underlying structural abnormality of the brain are more susceptible to Todd's phenomenon. Unusual manifestations of Todd's phenomenon are rare but clinically relevant and are decisive in therapeutic decision-making. Our patient presents a rare manifestation of Todd's phenomenon as ptosis and ophthalmoparesis in an elderly male with no underlying structural brain abnormalities that resolved within three weeks. Further research into the causes is needed to distinguish it from a stroke.
Language	English
Publishing date	2022-06-20
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.26108
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Knowledge and practice regarding cancer screening in Nepal: a systematic review and meta-analysis.

Adhikari, Ayush / Kashyap, Basant / Acharya, Subi / Sharma, Supriya / Gurung, Shekhar / Yadav, Rupesh Kumar / Budhathoki, Pravash

Annals of medicine and surgery (2012)

2023 Volume 86, Issue 1, Page(s) 382–391

Abstract: Background: Cancer screening utilization can aid in the early diagnosis and treatment of cancer. However, the current scenario of the knowledge and practice regarding cancer screening remains unclear as the authors do not have sufficient studies. Hence, ...

Abstract	Background: Cancer screening utilization can aid in the early diagnosis and treatment of cancer. However, the current scenario of the knowledge and practice regarding cancer screening remains unclear as the authors do not have sufficient studies. Hence, the authors conducted this systematic review and meta-analysis to assess the situation of cancer screening utilization and knowledge. Methods: A systematic literature review was conducted to identify all studies on knowledge and practice regarding cancer screening in the Nepalese population. Data extraction and analysis were done with SPSS and CMA-3. Results: The authors identified a total of 5238 studies after database searching, and 19 studies were included in a narrative synthesis. Lack of awareness and knowledge was the major barrier in cervical, breast, and testicular cancer screening. In cervical cancer screening, the most common reason for screening was the advice of health personnel in 85% of respondents, and the barrier was lack of awareness in 49.33% of participants. Conclusion: The knowledge and practice of cancer screening is lacking in Nepal, as shown by our review. More educational and awareness programs, easy access to screening services, and elimination of sociocultural barriers are necessary to increase the utilization of screening services.
Language	English
Publishing date	2023-11-23
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2745440-X
ISSN	2049-0801
ISSN	2049-0801
DOI	10.1097/MS9.0000000000001529
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Intimate Partner Violence During Pregnancy in South Asia: Systematic Review and Meta-Analysis.

Nepal, Samata / Atreya, Alok / Shrestha, Dhan Bahadur / Budhathoki, Pravash / Lamichhane, Samit / Nepal, Sarbin / Marahatta, Achyut / Dhital, Rolina

Journal of Nepal Health Research Council

2023 Volume 20, Issue 3, Page(s) 562–569

Abstract: Background: This systematic review collated the literature on the prevalence rate of different types of intimate partner violence (IPV) during pregnancy in South Asia.: Methods: Systematic literature searches were conducted in four major databases ( ... ...

Abstract	Background: This systematic review collated the literature on the prevalence rate of different types of intimate partner violence (IPV) during pregnancy in South Asia. Methods: Systematic literature searches were conducted in four major databases (Embase, Scopus, PubMed, PubMed Central) to identify relevant articles published from the inception of each database to May 2021, which reported data on the prevalence of intimate partner violence during pregnancy in South Asia. The Joanna Briggs Institute critical appraisal tool for prevalence studies was used to assess the risk of bias in individual studies. A random-effects model was used to calculate the pooled prevalence and corresponding 95% confidence interval due to significant between-study heterogeneity. Results: Thirty-seven studies were reviewed which showed an overall prevalence of IPV from South Asian countries was 23.4% (physical violence: 13.6%; sexual violence: 8.5%; emotional violence: 20.2%). Conclusions: There was a higher prevalence of intimate partner violence during pregnancy reported, with an overall prevalence ranging from 1.7% to 66.4% across studies. Emotional violence was more prevalent form when compared to sexual or physical violence.
MeSH term(s)	Pregnancy ; Female ; Humans ; Asia, Southern ; Risk Factors ; Nepal/epidemiology ; Intimate Partner Violence ; Cross-Sectional Studies ; Prevalence
Language	English
Publishing date	2023-03-07
Publishing country	Nepal
Document type	Meta-Analysis ; Systematic Review ; Journal Article
ZDB-ID	2551251-1
ISSN	1999-6217 ; 1999-6217
ISSN (online)	1999-6217
ISSN	1999-6217
DOI	10.33314/jnhrc.v20i3.3983
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Comparison of accidental pediatric scald burns in a tertiary care center: hot cauldron burns versus accidental spill burns.

Nakarmi, Kiran Kishor / Pathak, Bishnu Deep / Shrestha, Dhan / Budhathoki, Pravash / Rai, Shankar Man

F1000Research

2021 Volume 10, Page(s) 1086

Abstract: Background: ...

Abstract	Background:
MeSH term(s)	Burns/epidemiology ; Burns/etiology ; Child ; Cross-Sectional Studies ; Hospitalization ; Hot Temperature ; Humans ; Tertiary Care Centers
Language	English
Publishing date	2021-10-26
Publishing country	England
Document type	Journal Article
ZDB-ID	2699932-8
ISSN	2046-1402 ; 2046-1402
ISSN (online)	2046-1402
ISSN	2046-1402
DOI	10.12688/f1000research.73840.2
Database	MEDical Literature Analysis and Retrieval System OnLINE

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