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  1. Book ; Online ; E-Book: Infectious disease epidemiology

    Oren, Eyal / Brown, Heidi E.

    an introduction

    2023  

    Abstract: The field of infectious disease epidemiology has been front-and-center for the past few years. With the COVID-19 pandemic, an opportunity arose to provide "armchair epidemiologists" with a deeper understanding of the population-level impacts of ... ...

    Author's details Eyal Oren and Heidi E. Brown
    Abstract "The field of infectious disease epidemiology has been front-and-center for the past few years. With the COVID-19 pandemic, an opportunity arose to provide "armchair epidemiologists" with a deeper understanding of the population-level impacts of infectious diseases, and the tools available to control them. This field has its own unique culture and set of tools and rules. We will utilize a whole new vocabulary in this book, from how to consider transmission-with the idea of a disease reproductive rate-to how disease is dispersed or clustered, and to how to design a study. As the reader will see, infectious disease epidemiologists seek to learn who is sick, why they are sick, and when and where they became sick"--
    Keywords Epidemics
    Subject code 306.461
    Language English
    Size 1 online resource (275 pages)
    Publisher Springer Publishing Company, LLC
    Publishing place New York, New York
    Document type Book ; Online ; E-Book
    Note Includes index.
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 0-8261-5674-6 ; 9780826156730 ; 978-0-8261-5674-7 ; 0826156738
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: The Association between Message Framing and Intention to Vaccinate Predictive of Hepatitis A Vaccine Uptake.

    Satybaldiyeva, Nora / Martinez, Lourdes S / Cooper, Brittany / Oren, Eyal

    International journal of environmental research and public health

    2024  Volume 21, Issue 2

    Abstract: As ongoing, sporadic outbreaks of hepatitis A virus (HAV) infections present public health challenges, it is critical to understand public perceptions about HAV, especially regarding vaccination. This study examines whether message framing changes the ... ...

    Abstract As ongoing, sporadic outbreaks of hepatitis A virus (HAV) infections present public health challenges, it is critical to understand public perceptions about HAV, especially regarding vaccination. This study examines whether message framing changes the intention to vaccinate against HAV and self-reported vaccine behavior. Using a randomized controlled trial (N = 472) in February 2019 via Amazon Mechanical Turk, participants were randomized to one of four HAV vaccination message groups or a no-message control group. The message groups varied in their emphasis on the nature of outcomes (gain versus loss) and for whom (individual versus collective). The message frames were compared by intention to vaccinate, differences in message characteristics, and behavioral determinants. There was no difference in intention to vaccinate between gain- versus loss-framed messages (MD = 0.1, 95% CI = -0.1, 0.3) and individual- versus collective-framed messages (MD = 0.1, 95% CI = -0.1, 0.3). The intention to vaccinate against HAV in the no-message control group was very similar to that in the message groups. However, gain-framed messages were rated more positively in valence than loss-framed messages (MD = -0.5, 95% CI = -0.7, -0.3), which may be helpful for cultivating a positive public perception of HAV vaccination. The study also highlights the importance of comparing message frames to a no-message control in designing health communication messaging promoting HAV vaccination.
    MeSH term(s) Humans ; Intention ; Hepatitis A Vaccines/therapeutic use ; Vaccination ; Patient Acceptance of Health Care ; Self Report ; Health Promotion
    Chemical Substances Hepatitis A Vaccines
    Language English
    Publishing date 2024-02-10
    Publishing country Switzerland
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph21020207
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A Pregnant Woman With Severe Symptomatic Aortic Stenosis: How Should We Treat?

    Yagel, Oren / Alter, Roie / Nissan, Batel / Zwas, Donna R / Rosenbloom, Joshua I / Eyal, Ophir / Golomb, Mordechai / Planer, David / Elbaz-Greener, Gabby

    JACC. Case reports

    2024  Volume 29, Issue 3, Page(s) 102205

    Abstract: A 31-year-old woman with end-stage kidney disease and with a bicuspid aortic valve presented with acute heart failure in the second trimester of pregnancy. The patient received a diagnosis of severe aortic stenosis and chose to continue the pregnancy ... ...

    Abstract A 31-year-old woman with end-stage kidney disease and with a bicuspid aortic valve presented with acute heart failure in the second trimester of pregnancy. The patient received a diagnosis of severe aortic stenosis and chose to continue the pregnancy against medical advice. Following a multidisciplinary team consultation, she underwent urgent transcatheter aortic valve replacement.
    Language English
    Publishing date 2024-01-05
    Publishing country Netherlands
    Document type Case Reports
    ISSN 2666-0849
    ISSN (online) 2666-0849
    DOI 10.1016/j.jaccas.2023.102205
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Stress and asthma: Physiological manifestations and clinical implications.

    Oren, Eyal / Martinez, Fernando D

    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology

    2020  Volume 125, Issue 4, Page(s) 372–373.e1

    MeSH term(s) Asthma/immunology ; Asthma/psychology ; Humans ; Stress, Psychological/immunology
    Language English
    Publishing date 2020-07-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1228189-x
    ISSN 1534-4436 ; 0003-4738 ; 1081-1206
    ISSN (online) 1534-4436
    ISSN 0003-4738 ; 1081-1206
    DOI 10.1016/j.anai.2020.07.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Machine learning-based modeling of high-pressure phase diagrams: Anomalous melting of Rb.

    Oren, Eyal / Kartoon, Daniela / Makov, Guy

    The Journal of chemical physics

    2022  Volume 157, Issue 1, Page(s) 14502

    Abstract: Modeling of phase diagrams and, in particular, the anomalous re-entrant melting curves of alkali metals is an open challenge for interatomic potentials. Machine learning-based interatomic potentials have shown promise in overcoming this challenge, unlike ...

    Abstract Modeling of phase diagrams and, in particular, the anomalous re-entrant melting curves of alkali metals is an open challenge for interatomic potentials. Machine learning-based interatomic potentials have shown promise in overcoming this challenge, unlike earlier embedded atom-based approaches. We introduce a relatively simple and inexpensive approach to develop, train, and validate a neural network-based, wide-ranging interatomic potential transferable across both temperature and pressure. This approach is based on training the potential at high pressures only in the liquid phase and on validating its transferability on the relatively easy-to-calculate cold compression curve. Our approach is demonstrated on the phase diagram of Rb for which we reproduce the cold compression curve over the Rb-I (BCC), Rb-II (FCC), and Rb-V (tI4) phases, followed by the high-pressure melting curve including the re-entry after the maximum and then the minimum at the triple liquid-FCC-BCC point. Furthermore, our potential is able to partially capture even the very recently reported liquid-liquid transition in Rb, indicating the utility of machine learning-based potentials.
    Language English
    Publishing date 2022-07-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3113-6
    ISSN 1089-7690 ; 0021-9606
    ISSN (online) 1089-7690
    ISSN 0021-9606
    DOI 10.1063/5.0088089
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Effectiveness of alternative semester break schedules on reducing COVID-19 incidence on college campuses.

    Lehnig, Chris L / Oren, Eyal / Vaidya, Naveen K

    Scientific reports

    2022  Volume 12, Issue 1, Page(s) 2116

    Abstract: Despite COVID-19 vaccination programs, the threat of new SARS-CoV-2 strains and continuing pockets of transmission persists. While many U.S. universities replaced their traditional nine-day spring 2021 break with multiple breaks of shorter duration, the ... ...

    Abstract Despite COVID-19 vaccination programs, the threat of new SARS-CoV-2 strains and continuing pockets of transmission persists. While many U.S. universities replaced their traditional nine-day spring 2021 break with multiple breaks of shorter duration, the effects these schedules have on reducing COVID-19 incidence remains unclear. The main objective of this study is to quantify the impact of alternative break schedules on cumulative COVID-19 incidence on university campuses. Using student mobility data and Monte Carlo simulations of returning infectious student size, we developed a compartmental susceptible-exposed-infectious-asymptomatic-recovered (SEIAR) model to simulate transmission dynamics among university students. As a case study, four alternative spring break schedules were derived from a sample of universities and evaluated. Across alternative multi-break schedules, the median percent reduction of total semester COVID-19 incidence, relative to a traditional nine-day break, ranged from 2 to 4% (for 2% travel destination prevalence) and 8-16% (for 10% travel destination prevalence). The maximum percent reduction from an alternate break schedule was estimated to be 37.6%. Simulation results show that adjusting academic calendars to limit student travel can reduce disease burden. Insights gleaned from our simulations could inform policies regarding appropriate planning of schedules for upcoming semesters upon returning to in-person teaching modalities.
    MeSH term(s) Adolescent ; Adult ; COVID-19/epidemiology ; COVID-19/transmission ; Curriculum ; Female ; Humans ; Incidence ; Male ; Models, Biological ; SARS-CoV-2 ; Students ; Universities
    Language English
    Publishing date 2022-02-08
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-022-06260-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Effectiveness of alternative semester break schedules on reducing COVID-19 incidence on college campuses

    Chris L. Lehnig / Eyal Oren / Naveen K. Vaidya

    Scientific Reports, Vol 12, Iss 1, Pp 1-

    2022  Volume 8

    Abstract: Abstract Despite COVID-19 vaccination programs, the threat of new SARS-CoV-2 strains and continuing pockets of transmission persists. While many U.S. universities replaced their traditional nine-day spring 2021 break with multiple breaks of shorter ... ...

    Abstract Abstract Despite COVID-19 vaccination programs, the threat of new SARS-CoV-2 strains and continuing pockets of transmission persists. While many U.S. universities replaced their traditional nine-day spring 2021 break with multiple breaks of shorter duration, the effects these schedules have on reducing COVID-19 incidence remains unclear. The main objective of this study is to quantify the impact of alternative break schedules on cumulative COVID-19 incidence on university campuses. Using student mobility data and Monte Carlo simulations of returning infectious student size, we developed a compartmental susceptible-exposed-infectious-asymptomatic-recovered (SEIAR) model to simulate transmission dynamics among university students. As a case study, four alternative spring break schedules were derived from a sample of universities and evaluated. Across alternative multi-break schedules, the median percent reduction of total semester COVID-19 incidence, relative to a traditional nine-day break, ranged from 2 to 4% (for 2% travel destination prevalence) and 8–16% (for 10% travel destination prevalence). The maximum percent reduction from an alternate break schedule was estimated to be 37.6%. Simulation results show that adjusting academic calendars to limit student travel can reduce disease burden. Insights gleaned from our simulations could inform policies regarding appropriate planning of schedules for upcoming semesters upon returning to in-person teaching modalities.
    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2022-02-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Temporal gene expression patterns in the coral

    Rinsky, Mieka / Weizman, Eviatar / Ben-Asher, Hiba Waldman / Eyal, Gal / Zhu, Bokai / Levy, Oren

    Science advances

    2022  Volume 8, Issue 37, Page(s) eabo6467

    Abstract: Studying chronobiology in reef-building corals is challenging due to the tightly coupled symbiosis with their photosynthetic algae, Symbiodiniaceae. Although symbiosis requires metabolic synchronization and coordination of cellular processes in the ... ...

    Abstract Studying chronobiology in reef-building corals is challenging due to the tightly coupled symbiosis with their photosynthetic algae, Symbiodiniaceae. Although symbiosis requires metabolic synchronization and coordination of cellular processes in the holobiont, the cross-talk between the host and symbiont's clocks is still puzzling. Here, we use the mesophotic coral
    Language English
    Publishing date 2022-09-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2810933-8
    ISSN 2375-2548 ; 2375-2548
    ISSN (online) 2375-2548
    ISSN 2375-2548
    DOI 10.1126/sciadv.abo6467
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: New Analytical Approach to Quinolizidine Alkaloids and Their Assumed Biosynthesis Pathways in Lupin Seeds.

    Namdar, Dvory / Mulder, Patrick P J / Ben-Simchon, Eyal / Hacham, Yael / Basheer, Loai / Cohen, Ofer / Sternberg, Marcelo / Shelef, Oren

    Toxins

    2024  Volume 16, Issue 3

    Abstract: Alkaloids play an essential role in protecting plants against herbivores. Humans can also benefit from the pharmacological effects of these compounds. Plants produce an immense variety of structurally different alkaloids, including quinolizidine ... ...

    Abstract Alkaloids play an essential role in protecting plants against herbivores. Humans can also benefit from the pharmacological effects of these compounds. Plants produce an immense variety of structurally different alkaloids, including quinolizidine alkaloids, a group of bi-, tri-, and tetracyclic compounds produced by
    MeSH term(s) Humans ; Quinolizidine Alkaloids ; Lupinus ; Chromatography, Liquid ; Tandem Mass Spectrometry ; Seeds
    Chemical Substances Quinolizidine Alkaloids
    Language English
    Publishing date 2024-03-21
    Publishing country Switzerland
    Document type Review ; Journal Article
    ZDB-ID 2518395-3
    ISSN 2072-6651 ; 2072-6651
    ISSN (online) 2072-6651
    ISSN 2072-6651
    DOI 10.3390/toxins16030163
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: A retinoscopic survey of donkeys and goats.

    Pe'er, Oren / Gantz, Liat / Gal, Eyal / Ofri, Ron

    Veterinary ophthalmology

    2023  Volume 26, Issue 5, Page(s) 385–392

    Abstract: Purpose: Assess the refractive states of donkeys and goats.: Methods: Forty-two donkeys and 28 goats were enrolled. The mean ± SD ages were 7.68 ± 7.33 years for donkeys and 4.26 ± 2.33 years for goats. Seven donkeys and one goat were <6 months old. ... ...

    Abstract Purpose: Assess the refractive states of donkeys and goats.
    Methods: Forty-two donkeys and 28 goats were enrolled. The mean ± SD ages were 7.68 ± 7.33 years for donkeys and 4.26 ± 2.33 years for goats. Seven donkeys and one goat were <6 months old. Retinoscopy was performed in alert animals, following cycloplegia in goats but not in donkeys. Normality was determined using the Kolmogorov-Smirnov test. The two primary meridians and two eyes were compared using Pearson's correlation and paired Student's t-tests. The association between refractive states and age was examined using one-way ANOVA in donkeys and a paired Student's t-test in goats. One-sample t-tests were conducted to assess if the refractive error distributions were significantly different from "0".
    Results: The mean ± SD spherical equivalent (SE) refractive errors of the right and left donkey eyes were -0.80 ± 1.03 D and -0.35 ± 0.95 D, respectively. The majority (86%) of the donkeys had an astigmatic refraction and eight (19%) had anisometropia. The mean SE refractive errors of the right and left goat eyes were -0.15 ± 1.1 D and -0.18 ± 1.2 D, respectively. The majority (54%) of the goat eyes had an astigmatic refraction and five (18%) had anisometropia. The right and left eye SE refractive errors were positively correlated in both species (both p = .9). Age was not correlated with refractive error in both donkeys (p = .09) and goats (p = .6).
    Conclusions: Both goats and donkeys are emmetropic.
    MeSH term(s) Animals ; Retinoscopy ; Anisometropia/veterinary ; Equidae ; Goats ; Refractive Errors/veterinary ; Refraction, Ocular ; Prevalence ; Goat Diseases
    Language English
    Publishing date 2023-06-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 2011043-1
    ISSN 1463-5224 ; 1463-5216
    ISSN (online) 1463-5224
    ISSN 1463-5216
    DOI 10.1111/vop.13126
    Database MEDical Literature Analysis and Retrieval System OnLINE

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