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  1. Article ; Online: Intravenous Fosfomycin: The Underdog Player in the Treatment of Carbapenem-resistant Acinetobacter baumannii Infections.

    Guastalegname, Maurizio / Trecarichi, Enrico Maria / Russo, Alessandro

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2023  Volume 77, Issue 12, Page(s) 1736–1737

    MeSH term(s) Humans ; Fosfomycin/therapeutic use ; Acinetobacter baumannii ; Anti-Bacterial Agents/therapeutic use ; Carbapenems/pharmacology ; Carbapenems/therapeutic use ; Microbial Sensitivity Tests
    Chemical Substances Fosfomycin (2N81MY12TE) ; Anti-Bacterial Agents ; Carbapenems
    Language English
    Publishing date 2023-07-22
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciad435
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Could Chloroquine /Hydroxychloroquine Be Harmful in Coronavirus Disease 2019 (COVID-19) Treatment?

    Guastalegname, Maurizio / Vallone, Alfredo

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2020  Volume 71, Issue 15, Page(s) 888–889

    MeSH term(s) Antiviral Agents ; Betacoronavirus ; COVID-19 ; Chloroquine ; Coronavirus ; Coronavirus Infections/drug therapy ; Coronavirus Infections/epidemiology ; Humans ; Hydroxychloroquine ; Pandemics ; Pneumonia, Viral/epidemiology ; SARS-CoV-2 ; COVID-19 Drug Treatment
    Chemical Substances Antiviral Agents ; Hydroxychloroquine (4QWG6N8QKH) ; Chloroquine (886U3H6UFF)
    Keywords covid19
    Language English
    Publishing date 2020-03-11
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciaa321
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  4. Article ; Online: Could Chloroquine /Hydroxychloroquine Be Harmful in Coronavirus Disease 2019 (COVID-19) Treatment?

    Guastalegname, Maurizio / Vallone, Alfredo

    Clinical Infectious Diseases

    2020  Volume 71, Issue 15, Page(s) 888–889

    Keywords Microbiology (medical) ; Infectious Diseases ; covid19
    Language English
    Publisher Oxford University Press (OUP)
    Publishing country uk
    Document type Article ; Online
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciaa321
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  5. Article: An Outbreak of Human Systemic Anthrax, including One Case of Anthrax Meningitis, Occurred in Calabria Region (Italy): A Description of a Successful One Health Approach.

    Guastalegname, Maurizio / Rondinone, Valeria / Lucifora, Giuseppe / Vallone, Alfredo / D'Argenio, Laura / Petracca, Giovanni / Giordano, Antonia / Serrecchia, Luigina / Manzulli, Viviana / Pace, Lorenzo / Fasanella, Antonio / Simone, Domenico / Cipolletta, Dora / Galante, Domenico

    Life (Basel, Switzerland)

    2022  Volume 12, Issue 6

    Abstract: In this report, three cases of human cutaneous anthrax are described, one complicated by meningitis, and all were linked to a single infected bullock. A 41-year-old male truck driver, along with two male slaughterhouse workers, 45 and 42, were ... ...

    Abstract In this report, three cases of human cutaneous anthrax are described, one complicated by meningitis, and all were linked to a single infected bullock. A 41-year-old male truck driver, along with two male slaughterhouse workers, 45 and 42, were hospitalized for necrotic lesions of the arm associated with edema of the limb and high fever. All three patients were involved in transporting a bullock to the slaughterhouse. Microbiological examination on the prescapular lymph node and a piece of muscle from the bullock carcass showed the presence of
    Language English
    Publishing date 2022-06-17
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2662250-6
    ISSN 2075-1729
    ISSN 2075-1729
    DOI 10.3390/life12060909
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  6. Article: Healthcare-associated pneumonia: a never-ending story.

    Russo, Alessandro / Falcone, Marco / Giuliano, Simone / Guastalegname, Maurizio / Venditti, Mario

    Infectious disease reports

    2014  Volume 6, Issue 2, Page(s) 5387

    Language English
    Publishing date 2014-06-19
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2036-7430
    ISSN 2036-7430
    DOI 10.4081/idr.2014.5387
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: An Outbreak of Human Systemic Anthrax, including One Case of Anthrax Meningitis, Occurred in Calabria Region (Italy)

    Maurizio Guastalegname / Valeria Rondinone / Giuseppe Lucifora / Alfredo Vallone / Laura D’Argenio / Giovanni Petracca / Antonia Giordano / Luigina Serrecchia / Viviana Manzulli / Lorenzo Pace / Antonio Fasanella / Domenico Simone / Dora Cipolletta / Domenico Galante

    Life, Vol 12, Iss 909, p

    A Description of a Successful One Health Approach

    2022  Volume 909

    Abstract: In this report, three cases of human cutaneous anthrax are described, one complicated by meningitis, and all were linked to a single infected bullock. A 41-year-old male truck driver, along with two male slaughterhouse workers, 45 and 42, were ... ...

    Abstract In this report, three cases of human cutaneous anthrax are described, one complicated by meningitis, and all were linked to a single infected bullock. A 41-year-old male truck driver, along with two male slaughterhouse workers, 45 and 42, were hospitalized for necrotic lesions of the arm associated with edema of the limb and high fever. All three patients were involved in transporting a bullock to the slaughterhouse. Microbiological examination on the prescapular lymph node and a piece of muscle from the bullock carcass showed the presence of Bacillus anthracis . The three patients underwent a biopsy of the affected tissues, and all samples tested positive for B. anthracis DNA using PCR. Furthermore, the truck driver also complained of an intense headache, and a CSF sampling was performed, showing him positive for B. anthracis by PCR, confirming the presumptive diagnosis of meningitis. Fast diagnosis and appropriate treatment are crucial for the management of human anthrax. Cooperation between human and veterinary medicine proved successful in diagnosing and resolving three human anthrax cases, confirming the reliability of the One Health approach for the surveillance of zoonoses.
    Keywords Bacillus anthracis ; One Health ; cutaneous anthrax ; meningitis ; antibiotic treatment ; epidemiology ; Science ; Q
    Subject code 616
    Language English
    Publishing date 2022-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Candidemia subsequent to severe infection due to Clostridium difficile: is there a link?

    Guastalegname, Maurizio / Russo, Alessandro / Falcone, Marco / Giuliano, Simone / Venditti, Mario

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2013  Volume 57, Issue 5, Page(s) 772–774

    MeSH term(s) Aminoglycosides/pharmacology ; Candida/drug effects ; Clostridium Infections/drug therapy ; Clostridium difficile/pathogenicity ; Enterococcus/drug effects ; Female ; Humans ; Male ; Vancomycin/pharmacology
    Chemical Substances Aminoglycosides ; Vancomycin (6Q205EH1VU)
    Language English
    Publishing date 2013-09
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/cit362
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  9. Article ; Online: Healthcare-associated pneumonia

    Alessandro Russo / Marco Falcone / Simone Giuliano / Maurizio Guastalegname / Mario Venditti

    Infectious Disease Reports, Vol 6, Iss

    a never-ending story

    2014  Volume 2

    Abstract: ...

    Abstract -
    Keywords Other systems of medicine ; RZ201-999
    Language English
    Publishing date 2014-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Severe community onset healthcare-associated Clostridium difficile infection complicated by carbapenemase producing Klebsiella pneumoniae bloodstream infection.

    Giuliano, Simone / Guastalegname, Maurizio / Jenco, Miryam / Morelli, Andrea / Falcone, Marco / Venditti, Mario

    BMC infectious diseases

    2014  Volume 14, Page(s) 475

    Abstract: Background: Clostridium difficile infection (CDI) and Klebsiella pneumoniae carbapenemase producing-Klebsiella pneumoniae (KPC-Kp) bloodstream infection (BSI) are emerging health-care associated (HCA) diseases of public health concern, in terms of ... ...

    Abstract Background: Clostridium difficile infection (CDI) and Klebsiella pneumoniae carbapenemase producing-Klebsiella pneumoniae (KPC-Kp) bloodstream infection (BSI) are emerging health-care associated (HCA) diseases of public health concern, in terms of morbidity, mortality, and insufficient response to antibiotic therapy. Both agents can be acquired in the hospital but clinical disease can develop in a community setting, after discharge. We report here a putative link between the above-mentioned healthcare associated infections that appeared as a dramatic community onset disease with a fulminant fatal outcome.
    Case presentation: We describe the case of a 63 year old man affected by severe CDI. Even though the patient underwent 72 hours of standard CDI antibiotic treatment, the clinical course was complicated by toxic megacolon and KPC-Kp BSI. The patient died 24 hours after total colectomy.
    Conclusion: The impact of HCA-BSIs in complicating CDI is still unknown. Intestinal inflammatory injury and disruption of intestinal flora by standard antibiotic treatment could be responsible for promoting difficult-to-treat infections in CDI. By preserving intestinal flora, Fidaxomicin could have a crucial role in preventing BSIs complicating severe CDI.
    MeSH term(s) Aminoglycosides/chemistry ; Aminoglycosides/therapeutic use ; Anti-Bacterial Agents/therapeutic use ; Bacteremia/mortality ; Bacterial Proteins/chemistry ; Clostridioides difficile ; Clostridium Infections/blood ; Clostridium Infections/drug therapy ; Clostridium Infections/mortality ; Coinfection ; Cross Infection/drug therapy ; Cross Infection/mortality ; Fatal Outcome ; Fidaxomicin ; Hospitals ; Humans ; Klebsiella Infections/mortality ; Klebsiella pneumoniae ; Male ; Middle Aged ; beta-Lactamases/chemistry
    Chemical Substances Aminoglycosides ; Anti-Bacterial Agents ; Bacterial Proteins ; beta-Lactamases (EC 3.5.2.6) ; carbapenemase (EC 3.5.2.6) ; Fidaxomicin (Z5N076G8YQ)
    Language English
    Publishing date 2014-09-01
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1471-2334
    ISSN (online) 1471-2334
    DOI 10.1186/1471-2334-14-475
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