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  1. Article ; Online: Could fluvoxamine keep COVID-19 patients out of hospitals and intensive care units?

    Marčec, Robert / Likić, Robert

    Croatian medical journal

    2021  Volume 62, Issue 1, Page(s) 95–100

    Language English
    Publishing date 2021-03-04
    Publishing country Croatia
    Document type Journal Article
    ZDB-ID 1157623-6
    ISSN 1332-8166 ; 0353-9504
    ISSN (online) 1332-8166
    ISSN 0353-9504
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 187: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Could Fluvoxamine Dose De-escalation Increase Treatment Compliance Without Sacrificing Efficacy in COVID-19 Patients?

    Marcec, Robert / Likic, Robert

    Clinical pharmacokinetics

    2022  Volume 61, Issue 9, Page(s) 1321–1323

    MeSH term(s) COVID-19/drug therapy ; Fluvoxamine/therapeutic use ; Humans ; Patient Compliance ; Serotonin Uptake Inhibitors ; Treatment Outcome
    Chemical Substances Serotonin Uptake Inhibitors ; Fluvoxamine (O4L1XPO44W)
    Language English
    Publishing date 2022-07-23
    Publishing country Switzerland
    Document type Letter
    ZDB-ID 197627-8
    ISSN 1179-1926 ; 0312-5963
    ISSN (online) 1179-1926
    ISSN 0312-5963
    DOI 10.1007/s40262-022-01154-x
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    Zs.A 1246: Show issues Location:
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  3. Article ; Online: The relationship between vaccine acceptance and COVID-19 mortality in Europe: A Cross-Country analysis of public opinion and Epidemiological data.

    Brnic, Stjepan / Buric, Bruno / Marcec, Robert / Likic, Robert

    Vaccine: X

    2023  Volume 15, Page(s) 100391

    Abstract: Introduction: More than two years after SARS-CoV-2 emerged in Wuhan, China, COVID-19 has become one of the most severe pandemics in modern human history. Prior to the widespread availability of specific vaccines in 2021, public opinion surveys indicated ...

    Abstract Introduction: More than two years after SARS-CoV-2 emerged in Wuhan, China, COVID-19 has become one of the most severe pandemics in modern human history. Prior to the widespread availability of specific vaccines in 2021, public opinion surveys indicated significant vaccine hesitancy in 26 European countries.
    Materials and methods: Epidemiological data on COVID-19 morbidity and mortality for 26 European countries were collected in November 2021 and compared with the proportions of people willing to receive the SARS-CoV-2 vaccine according to public opinion surveys analysed in 2020. Correlations between various variables were calculated using the Pearson correlation test and visualized with the R programming language.
    Results: Paired Student's
    Conclusion: Encouraging widespread immunization through vaccination was crucial for rapidly improving the epidemiological situation in Europe.
    Language English
    Publishing date 2023-09-19
    Publishing country England
    Document type Journal Article
    ISSN 2590-1362
    ISSN (online) 2590-1362
    DOI 10.1016/j.jvacx.2023.100391
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  4. Article ; Online: Postvaccination anaphylaxis and mRNA-based SARS-CoV-2 vaccines-Much ado about nothing?

    Marcec, Robert / Likic, Robert

    British journal of clinical pharmacology

    2021  Volume 87, Issue 9, Page(s) 3632–3633

    MeSH term(s) Anaphylaxis/chemically induced ; COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects ; Humans ; Vaccines, Synthetic/adverse effects ; mRNA Vaccines
    Chemical Substances COVID-19 Vaccines ; Vaccines, Synthetic
    Language English
    Publishing date 2021-02-12
    Publishing country England
    Document type Letter
    ZDB-ID 188974-6
    ISSN 1365-2125 ; 0306-5251 ; 0264-3774
    ISSN (online) 1365-2125
    ISSN 0306-5251 ; 0264-3774
    DOI 10.1111/bcp.14763
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    Zs.A 1118: Show issues Location:
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  5. Article ; Online: Using Twitter for sentiment analysis towards AstraZeneca/Oxford, Pfizer/BioNTech and Moderna COVID-19 vaccines.

    Marcec, Robert / Likic, Robert

    Postgraduate medical journal

    2021  Volume 98, Issue 1161, Page(s) 544–550

    Abstract: Introduction: A worldwide vaccination campaign is underway to bring an end to the SARS-CoV-2 pandemic; however, its success relies heavily on the actual willingness of individuals to get vaccinated. Social media platforms such as Twitter may prove to be ...

    Abstract Introduction: A worldwide vaccination campaign is underway to bring an end to the SARS-CoV-2 pandemic; however, its success relies heavily on the actual willingness of individuals to get vaccinated. Social media platforms such as Twitter may prove to be a valuable source of information on the attitudes and sentiment towards SARS-CoV-2 vaccination that can be tracked almost instantaneously.
    Materials and methods: The Twitter academic Application Programming Interface was used to retrieve all English-language tweets mentioning AstraZeneca/Oxford, Pfizer/BioNTech and Moderna vaccines in 4 months from 1 December 2020 to 31 March 2021. Sentiment analysis was performed using the AFINN lexicon to calculate the daily average sentiment of tweets which was evaluated longitudinally and comparatively for each vaccine throughout the 4 months.
    Results: A total of 701 891 tweets have been retrieved and included in the daily sentiment analysis. The sentiment regarding Pfizer and Moderna vaccines appeared positive and stable throughout the 4 months, with no significant differences in sentiment between the months. In contrast, the sentiment regarding the AstraZeneca/Oxford vaccine seems to be decreasing over time, with a significant decrease when comparing December with March (p<0.0000000001, mean difference=-0.746, 95% CI=-0.915 to -0.577).
    Conclusion: Lexicon-based Twitter sentiment analysis is a valuable and easily implemented tool to track the sentiment regarding SARS-CoV-2 vaccines. It is worrisome that the sentiment regarding the AstraZeneca/Oxford vaccine appears to be turning negative over time, as this may boost hesitancy rates towards this specific SARS-CoV-2 vaccine.
    MeSH term(s) 2019-nCoV Vaccine mRNA-1273 ; COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19 Vaccines ; Humans ; SARS-CoV-2 ; Sentiment Analysis ; Social Media ; Vaccines
    Chemical Substances COVID-19 Vaccines ; Vaccines ; 2019-nCoV Vaccine mRNA-1273 (EPK39PL4R4)
    Language English
    Publishing date 2021-08-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 80325-x
    ISSN 1469-0756 ; 0032-5473
    ISSN (online) 1469-0756
    ISSN 0032-5473
    DOI 10.1136/postgradmedj-2021-140685
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    Ua VI Zs.340: Show issues Location:
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  6. Article ; Online: Vitamin C utilisation in 2020: have we bought a lemon?

    Marcec, Robert / Posavec, Fran / Likic, Robert

    Postgraduate medical journal

    2022  Volume 98, Issue 1163, Page(s) 651–652

    MeSH term(s) Humans ; Ascorbic Acid/therapeutic use ; Vitamins
    Chemical Substances Ascorbic Acid (PQ6CK8PD0R) ; Vitamins
    Language English
    Publishing date 2022-07-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 80325-x
    ISSN 1469-0756 ; 0032-5473
    ISSN (online) 1469-0756
    ISSN 0032-5473
    DOI 10.1136/pmj-2022-141978
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ua VI Zs.340: Show issues Location:
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  7. Article ; Online: Brave, new and divided post-COVID-19 world.

    Marcec, Robert / Majta, Matea / Likic, Robert

    Postgraduate medical journal

    2022  Volume 98, Issue e2, Page(s) e133

    MeSH term(s) COVID-19 ; Humans ; SARS-CoV-2
    Language English
    Publishing date 2022-03-18
    Publishing country England
    Document type Letter
    ZDB-ID 80325-x
    ISSN 1469-0756 ; 0032-5473
    ISSN (online) 1469-0756
    ISSN 0032-5473
    DOI 10.1136/postgradmedj-2020-139572
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ua VI Zs.340: Show issues Location:
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  8. Article ; Online: A meta-analysis regarding fluvoxamine and hospitalization risk of COVID-19 patients: TOGETHER making a difference.

    Marcec, Robert / Dodig, Vinko Michael / Likic, Robert

    The Journal of infection

    2022  Volume 86, Issue 2, Page(s) 154–225

    MeSH term(s) Humans ; Fluvoxamine ; COVID-19 Drug Treatment ; COVID-19 ; Treatment Outcome ; Hospitalization
    Chemical Substances Fluvoxamine (O4L1XPO44W)
    Language English
    Publishing date 2022-11-18
    Publishing country England
    Document type Meta-Analysis ; Letter ; Comment
    ZDB-ID 424417-5
    ISSN 1532-2742 ; 0163-4453
    ISSN (online) 1532-2742
    ISSN 0163-4453
    DOI 10.1016/j.jinf.2022.11.011
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    Zs.A 1501: Show issues Location:
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    Zs.MG 48: Show issues

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  9. Article ; Online: Regdanvimab improves disease mortality and morbidity in patients with COVID-19: Too optimistic and too early to say?

    Marcec, Robert / Dodig, Vinko Michael / Likic, Robert

    The Journal of infection

    2022  Volume 86, Issue 1, Page(s) 66–117

    MeSH term(s) Humans ; COVID-19 ; Immunoglobulin G ; Antibodies, Monoclonal, Humanized/therapeutic use ; Morbidity
    Chemical Substances regdanvimab (I0BGE6P6I6) ; Immunoglobulin G ; Antibodies, Monoclonal, Humanized
    Language English
    Publishing date 2022-11-01
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 424417-5
    ISSN 1532-2742 ; 0163-4453
    ISSN (online) 1532-2742
    ISSN 0163-4453
    DOI 10.1016/j.jinf.2022.10.030
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1501: Show issues Location:
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  10. Article ; Online: Evolving Trends and Economic Burden of Benzodiazepine Use: Insights From a 10-Year Predictive Model.

    Koren, Andro / Koren, Luciana / Marcec, Robert / Marcinko, Darko / Likic, Robert

    Value in health regional issues

    2023  Volume 40, Page(s) 70–73

    Abstract: Objectives: Benzodiazepines (BZDs) are widely prescribed in Croatia to treat anxiety, insomnia, mood disorders, and epileptic seizures. Long-term BZD use is associated with memory loss, Alzheimer's disease, dependence, addiction, falls in elderly ... ...

    Abstract Objectives: Benzodiazepines (BZDs) are widely prescribed in Croatia to treat anxiety, insomnia, mood disorders, and epileptic seizures. Long-term BZD use is associated with memory loss, Alzheimer's disease, dependence, addiction, falls in elderly populations, and increased traffic accident risk.
    Methods: Drug consumption data were obtained from the Agency for Medicinal Products and Medical Devices of Croatia website. Autoregressive integrated moving average models, constructed using R programming language, forecasted diazepam, alprazolam, and overall BZD utilization and financial costs at a national level over 10 years.
    Results: BZD consumption increased by up to 18.6% between 2012 and 2020. During the same period, diazepam utilization rose by 29.1%, and alprazolam consumption increased by 19.4%. Our model predicts that, by 2032, BZD, diazepam, and alprazolam utilization will increase substantially. The total projected financial expenditure for BZDs in 2032 is estimated at 14.22 million euros, with diazepam and alprazolam expenditures at 7.39 and 4.12 million euros, respectively. These increases will result in significant growth in healthcare spending and a rise in adverse effects related to long-term use.
    Conclusions: National healthcare decision makers should consider implementing regulatory and legislative measures to quantify, specify, and limit monthly BZD use for each patient. This would help control the negative side effects of prolonged BZD use while continuing to provide treatment for patients who genuinely need it.
    MeSH term(s) Humans ; Aged ; Benzodiazepines/adverse effects ; Alprazolam/adverse effects ; Financial Stress ; Diazepam/adverse effects ; Practice Patterns, Physicians'
    Chemical Substances Benzodiazepines (12794-10-4) ; Alprazolam (YU55MQ3IZY) ; Diazepam (Q3JTX2Q7TU)
    Language English
    Publishing date 2023-11-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2679127-4
    ISSN 2212-1102 ; 2212-1099
    ISSN (online) 2212-1102
    ISSN 2212-1099
    DOI 10.1016/j.vhri.2023.10.005
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    Zs.A 6969: Show issues Location:
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