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Article: Event-Related Potentials in Women on the Pill: Neural Correlates of Positive and Erotic Stimulus Processing in Oral Contraceptive Users.

Schmidt, Norina M / Hennig, Juergen / Munk, Aisha J L

2022 Volume 15, Page(s) 798823

Abstract: Background/Aims: ...

Abstract	Background/Aims:
Language	English
Publishing date	2022-01-04
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2411902-7
ISSN	1662-453X ; 1662-4548
ISSN (online)	1662-453X
ISSN	1662-4548
DOI	10.3389/fnins.2021.798823
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Interaction between serotonin and dopamine and impulsivity

Hennig, Juergen / Netter, Petra / Munk, Aisha J. L.

Personality and Individual Differences

A gene x gene - Interaction approach

2021

Abstract: Abstract not released by ... ...

Title translation	Interaktion zwischen Serotonin und Dopamin und Impulsivität: Ein Gen x Gen - Interaktion Ansatz (DeepL)
Abstract	Abstract not released by publisher
Keywords	Allele ; Alleles ; Dopamin ; Dopamine ; Genotypen ; Genotypes ; Impulsiveness ; Impulsivität ; Serotonin
Language	English
Document type	Article
ZDB-ID	625323-4
ISSN	0191-8869
ISSN	0191-8869
DOI	10.1016/j.paid.2020.110014
Database	PSYNDEX

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Article: Event-related potentials in women on the pill

Schmidt, Norina M. / Hennig, Juergen / Munk, Aisha J. L.

Frontiers in Neuroscience

Neural correlates of positive and erotic stimulus processing in oral contraceptive users

2022

Abstract: Background/Aims: Exposure toward positive emotional cues with - and without - reproductive significance plays a crucial role in daily life and regarding well-being as well as mental health. While possible adverse effects of oral contraceptive (OC) use on ...

Title translation	Ereignisbezogene Potenziale bei Frauen, die die Pille nehmen: Neuronale Korrelate der Verarbeitung positiver und erotischer Stimuli bei Anwenderinnen oraler Kontrazeptiva
Abstract	Background/Aims: Exposure toward positive emotional cues with - and without - reproductive significance plays a crucial role in daily life and regarding well-being as well as mental health. While possible adverse effects of oral contraceptive (OC) use on female mental and sexual health are widely discussed, neural processing of positive emotional stimuli has not been systematically investigated in association with OC use. Considering reported effects on mood, well-being and sexual function, and proposed associations with depression, it was hypothesized that OC users showed reduced neural reactivity toward positive and erotic emotional stimuli during early as well as later stages of emotional processing and also rated these stimuli as less pleasant and less arousing compared to naturally cycling (NC) women.Method: Sixty-two female subjects (29 NC and 33 OC) were assessed at three time points across the natural menstrual cycle and corresponding time points of the OC regimen. Early (early posterior negativity, EPN) and late (late positive potential, LPP) event-related potentials in reaction to positive, erotic and neutral stimuli were collected during an Emotional Picture Stroop Paradigm (EPSP). At each appointment, subjects provided saliva samples for analysis of gonadal steroid concentration. Valence and arousal ratings were collected at the last appointment.Results: Oral contraceptive users had significantly lower endogenous estradiol and progesterone concentrations compared to NC women. No significant group differences in either subjective stimulus evaluations or neural reactivity toward positive and erotic emotional stimuli were observed. For the OC group, LPP amplitudes in reaction to erotic vs. neutral pictures differed significantly between measurement times across the OC regimen.Discussion: In this study, no evidence regarding alterations of neural reactivity toward positive and erotic stimuli in OC users compared to NC was found. Possible confounding factors and lines for future research are elaborated and discussed.
Keywords	Emotional Content ; Emotional Processing ; Emotionale Verarbeitung ; Emotionaler Inhalt ; Estradiol ; Evoked Potentials ; Evozierte Potenziale ; Frauen ; Human Females ; Menstrual Cycle ; Menstruationszyklus ; Oral Contraceptives ; Orale Empfängnisverhütungsmittel ; Progesteron ; Progesterone ; Sex Hormones ; Sexualhormone ; Stimulus Parameters ; Stimulusparameter ; Östradiol
Language	English
Document type	Article
DOI	10.3389/fnins.2021.798823
Database	PSYNDEX

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Article ; Online: Fluctuations of estradiol during women's menstrual cycle: Influences on reactivity towards erotic stimuli in the late positive potential.

Munk, Aisha J L / Zoeller, Aaron C / Hennig, Juergen

Psychoneuroendocrinology

2018 Volume 91, Page(s) 11–19

Abstract: Background: While several studies examined the reactivity towards negative emotional stimuli across women's menstrual cycle, only few investigated responses to positive emotional cues in association with sexual hormones on a neural level. Therefore, the ...

Abstract	Background: While several studies examined the reactivity towards negative emotional stimuli across women's menstrual cycle, only few investigated responses to positive emotional cues in association with sexual hormones on a neural level. Therefore, the aim of the current EEG-experiment was to study the differential reactivity towards positive (erotic) words during the menstrual cycle (i.e. with fluctuations in the steroids estradiol and progesterone) in the late positive potential (LPP). Regarding reactivity towards erotic stimuli, the LPP is seen as the most relevant ERP-component, as more positive amplitudes in the LPP reflect larger incentive salience and higher arousal. The LPP towards erotic words was expected to be more pronounced during fertile phases of the menstrual cycle (around ovulation). Furthermore, associations with hormonal concentrations of estradiol and progesterone were investigated. Method: 19 young, free cycling women were tested in an Erotic Stroop paradigm during the follicular phase, ovulation, and the luteal phase in a balanced cross-over design, while electroencephalogram (EEG) was recorded. Results: LPPs in reaction to erotic compared to neutral words were larger in every phase. During the follicular phase and ovulation, higher estradiol-concentrations were associated with more positive LPP-amplitudes towards erotic- than to neutral words. No effects of progesterone, as well as no effects of cycle phase, were evident. Results are being discussed regarding implications for further research.
MeSH term(s)	Adolescent ; Adult ; Arousal/physiology ; Cues ; Emotions/physiology ; Erotica/psychology ; Estradiol/analysis ; Estradiol/metabolism ; Female ; Follicular Phase/physiology ; Humans ; Luteal Phase/physiology ; Menstrual Cycle/metabolism ; Menstrual Cycle/physiology ; Ovulation/physiology ; Progesterone/physiology ; Saliva/chemistry ; Sexual Behavior/physiology ; Young Adult
Chemical Substances	Progesterone (4G7DS2Q64Y) ; Estradiol (4TI98Z838E)
Language	English
Publishing date	2018-02-27
Publishing country	England
Document type	Journal Article
ZDB-ID	197636-9
ISSN	1873-3360 ; 0306-4530
ISSN (online)	1873-3360
ISSN	0306-4530
DOI	10.1016/j.psyneuen.2018.02.028
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Article: Motivational salience, impulsivity and testosterone in free cycling women

Munk, Aisha J. L. / Schmidt, Norina M. / Hennig, Juergen

Personality and Individual Differences

An ERP-study

2020

Abstract: Abstract not released by ... ...

Title translation	Motivationale Salienz, Impulsivität und Testosteron von Frauen mit freiem Menstruationszyklus: Eine ERP-Studie (DeepL)
Abstract	Abstract not released by publisher
Keywords	Evoked Potentials ; Evozierte Potenziale ; Impulsiveness ; Impulsivität ; Menstrual Cycle ; Menstruationszyklus ; Motivation ; P300 ; Stimulus Salience ; Stimulusaugenfälligkeit ; Testosteron ; Testosterone
Language	English
Document type	Article
ZDB-ID	625323-4
ISSN	0191-8869
ISSN	0191-8869
DOI	10.1016/j.paid.2020.109902
Database	PSYNDEX

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Article ; Online: Covid-19-Beyond virology: Potentials for maintaining mental health during lockdown.

Munk, Aisha J L / Schmidt, Norina M / Alexander, Nina / Henkel, Katrina / Hennig, Juergen

PloS one

2020 Volume 15, Issue 8, Page(s) e0236688

Abstract: Background: The current study aimed to assess prevalence of mental disorders during Covid-19 pandemic- and respective lockdown in Germany, and potential behaviors/states that can have protective functions on preventing severe mental problems. Assessing ... ...

Abstract	Background: The current study aimed to assess prevalence of mental disorders during Covid-19 pandemic- and respective lockdown in Germany, and potential behaviors/states that can have protective functions on preventing severe mental problems. Assessing prevalence of mental disorders, as well as to find potential protective variables is very important in order to determine people's psychological suffering. It provides the basis for teaching possible coping styles in order to prevent a major breakdown on mental health. Prevalence on mental disorders was expected to increase during the pandemic, especially depression, (general-/and health-) anxiety, panic attacks- and disorder, as well as obsessive-compulsive disorder. Additionally, potentially protective variables, such as resilience and coping, were included. Methods: N = 949 subjects completed an online-survey that asked for symptoms regarding depression, (health) anxiety, panic disorder, obsessive-compulsive disorder, and lock-down related behavior-starting 14 days after lockdown in Germany. Results: Prevalence of mental disorders in the current sample was much higher than usual prevalence of mental disorders, with 50.6% expressing at least one mental disorder. Resilience was associated with lower risks for any mental disorder (OR = 4.23, p < .0001, 95%CI = 3.21-5.57), as well as with any other measured mental illness (all ORs between = 2.82 for obsessive-compulsive disorder and OR = 41.44 for panic disorder, all p < .001). Similar results were obtained regarding coping (focus on positive). Conclusion: Results are highly relevant in order to provide a glance on what substantial influence the current pandemic- and lockdown situation has on mental health across the country, and possibly across the world. Possible ways in order to prevent deterioration and help coping with the current situation are being elaborated and discussed.
MeSH term(s)	Adaptation, Psychological ; Adult ; Betacoronavirus/isolation & purification ; COVID-19 ; Coronavirus Infections/pathology ; Coronavirus Infections/virology ; Female ; Germany/epidemiology ; Humans ; Internet ; Male ; Mental Disorders/diagnosis ; Mental Disorders/epidemiology ; Mental Disorders/etiology ; Mental Health ; Middle Aged ; Obsessive-Compulsive Disorder/diagnosis ; Obsessive-Compulsive Disorder/epidemiology ; Obsessive-Compulsive Disorder/etiology ; Odds Ratio ; Pandemics ; Panic Disorder/diagnosis ; Panic Disorder/epidemiology ; Panic Disorder/etiology ; Pneumonia, Viral/pathology ; Pneumonia, Viral/virology ; SARS-CoV-2 ; Surveys and Questionnaires ; Young Adult
Keywords	covid19
Language	English
Publishing date	2020-08-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0236688
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Covid-19—Beyond virology

Munk, Aisha J. L. / Schmidt, Norina M. / Alexander, Nina / Henkel, Katrina / Hennig, Juergen

PLOS ONE

Potentials for maintaining mental health during lockdown

2020 Volume 15, Issue 8, Page(s) e0236688

Keywords	General Biochemistry, Genetics and Molecular Biology ; General Agricultural and Biological Sciences ; General Medicine ; covid19
Language	English
Publisher	Public Library of Science (PLoS)
Publishing country	us
Document type	Article ; Online
ISSN	1932-6203
DOI	10.1371/journal.pone.0236688
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Covid-19-Beyond virology

Aisha J L Munk / Norina M Schmidt / Nina Alexander / Katrina Henkel / Juergen Hennig

PLoS ONE, Vol 15, Iss 8, p e

Potentials for maintaining mental health during lockdown.

2020 Volume 0236688

Abstract: Background The current study aimed to assess prevalence of mental disorders during Covid-19 pandemic- and respective lockdown in Germany, and potential behaviors/states that can have protective functions on preventing severe mental problems. Assessing ... ...

Abstract	Background The current study aimed to assess prevalence of mental disorders during Covid-19 pandemic- and respective lockdown in Germany, and potential behaviors/states that can have protective functions on preventing severe mental problems. Assessing prevalence of mental disorders, as well as to find potential protective variables is very important in order to determine people's psychological suffering. It provides the basis for teaching possible coping styles in order to prevent a major breakdown on mental health. Prevalence on mental disorders was expected to increase during the pandemic, especially depression, (general-/and health-) anxiety, panic attacks- and disorder, as well as obsessive-compulsive disorder. Additionally, potentially protective variables, such as resilience and coping, were included. Methods N = 949 subjects completed an online-survey that asked for symptoms regarding depression, (health) anxiety, panic disorder, obsessive-compulsive disorder, and lock-down related behavior-starting 14 days after lockdown in Germany. Results Prevalence of mental disorders in the current sample was much higher than usual prevalence of mental disorders, with 50.6% expressing at least one mental disorder. Resilience was associated with lower risks for any mental disorder (OR = 4.23, p < .0001, 95%CI = 3.21-5.57), as well as with any other measured mental illness (all ORs between = 2.82 for obsessive-compulsive disorder and OR = 41.44 for panic disorder, all p < .001). Similar results were obtained regarding coping (focus on positive). Conclusion Results are highly relevant in order to provide a glance on what substantial influence the current pandemic- and lockdown situation has on mental health across the country, and possibly across the world. Possible ways in order to prevent deterioration and help coping with the current situation are being elaborated and discussed.
Keywords	Medicine ; R ; Science ; Q ; covid19
Subject code	150
Language	English
Publishing date	2020-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Females' menstrual cycle and incentive salience: Insights on neural reaction towards erotic pictures and effects of gonadal hormones.

Munk, Aisha J L / Dickhaeuser, Lea / Breitinger, Eva / Hermann, Andrea / Strahler, Jana / Schmidt, Norina M / Hennig, Juergen

Comprehensive psychoneuroendocrinology

2020 Volume 3, Page(s) 100006

Abstract: Background: Studies in regard to womens' neural reactivity to erotic and other positive emotional cues in association with sexual hormones are relatively rare and findings rather inconclusive. Concerning the neural reactions towards erotic stimuli, the ... ...

Abstract	Background: Studies in regard to womens' neural reactivity to erotic and other positive emotional cues in association with sexual hormones are relatively rare and findings rather inconclusive. Concerning the neural reactions towards erotic stimuli, the late positive potential (LPP) is seen as the most relevant ERP-component: More positive amplitudes are supposed to reflect larger motivational salience and higher arousal in reaction to the presented stimuli. Therefore, it was expected that the LPP in reaction to erotic pictures would be more pronounced during fertile periods of the menstrual cycle around ovulation, as well as to be associated with estradiol-levels. A similar pattern was hypothesized to be present with testosterone-levels, whereas no association with progesterone was expected. Method: N = 35 free-cycling women completed an Erotic picture Stroop task (neutral, positive, and erotic stimuli, with three neutral- and three erotic subcategories) during follicular phase, ovulation and luteal phase, while EEG was recorded. Subjects provided saliva samples in order to determine estradiol-, progesterone-, and testosterone levels at each measuring time, and affective states were assessed using the Positive and Negative Affect Scale (PANAS). Results: LPPs in reaction to erotic-compared to positive- and neutral pictures were larger in every cycle phase. LPPs in reaction to erotic couples were strongest in comparison to every other (sub-) category. During ovulation, higher estradiol-concentrations were associated with lower LPP-amplitudes towards erotic-couples- than to neutral pictures. No effects of progesterone, no direct effect of testosterone, as well as no effects of cycle phase, were evident. Conclusion: Results partly contradict our hypotheses, as estradiol was expected to be positively associated with LPP during fertile stages. Possible differences between stimulus-entities (words v. pictures) and ideas for further research are being discussed.
Language	English
Publishing date	2020-07-12
Publishing country	England
Document type	Journal Article
ISSN	2666-4976
ISSN (online)	2666-4976
DOI	10.1016/j.cpnec.2020.100006
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Covid-19-beyond virology

Munk, Aisha J. L. / Schmidt, Norina M. / Alexander, Nina / Henkel, Katrina / Hennig, Juergen

PLoS ONE

Potentials for maintaining mental health during lockdown

2020 Volume 15, Issue 8, Page(s) No

Title translation	Covid-19 - jenseits der Virologie: Potenziale zur Aufrechterhaltung der psychischen Gesundheit während eines Lockdowns
Abstract	Background: The current study aimed to assess prevalence of mental disorders during Covid-19 pandemic- and respective lockdown in Germany, and potential behaviors/states that can have protective functions on preventing severe mental problems. Assessing prevalence of mental disorders, as well as to find potential protective variables is very important in order to determine people's psychological suffering. It provides the basis for teaching possible coping styles in order to prevent a major breakdown on mental health. Prevalence on mental disorders was expected to increase during the pandemic, especially depression, (general-/and health-) anxiety, panic attacks- and disorder, as well as obsessive-compulsive disorder. Additionally, potentially protective variables, such as resilience and coping, were included. Methods: N = 949 subjects completed an online-survey that asked for symptoms regarding depression, (health) anxiety, panic disorder, obsessive-compulsive disorder, and lock-down related behavior-starting 14 days after lockdown in Germany. Results: Prevalence of mental disorders in the current sample was much higher than usual prevalence of mental disorders, with 50.6% expressing at least one mental disorder. Resilience was associated with lower risks for any mental disorder (OR = 4.23, p < .0001, 95%CI = 3.21-5.57), as well as with any other measured mental illness (all ORs between = 2.82 for obsessive-compulsive disorder and OR = 41.44 for panic disorder, all p < .001). Similar results were obtained regarding coping (focus on positive). Conclusion: Results are highly relevant in order to provide a glance on what substantial influence the current pandemic- and lockdown situation has on mental health across the country, and possibly across the world. Possible ways in order to prevent deterioration and help coping with the current situation are being elaborated and discussed.
Keywords	Angst ; Anxiety ; Bewältigungsverhalten ; COVID-19 ; Coping Behavior ; Epidemiologie ; Epidemiology ; Major Depression ; Mental Disorders ; Mental Health ; Obsessive Compulsive Disorder ; Pandemics ; Pandemie ; Panic Disorder ; Panikstörungen ; Prevention ; Prävention ; Psychische Gesundheit ; Psychische Störungen ; Resilience (Psychological) ; Resilienz ; Social Isolation ; Soziale Isolation ; Zwangsstörung
Language	English
Document type	Article
ZDB-ID	2267670-3
ISSN	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0236688
Database	PSYNDEX

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