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Article ; Online: Covid-19 Pandemic: Need to Exercise Caution While Using Hypochlorite Sanitizer in Manufacturing Industries.

Bhaumik, S K

Journal of failure analysis & prevention

2020 Volume 21, Issue 2, Page(s) 345–347

Abstract: World is fighting Covid-19 pandemic since beginning of the year 2020. To prevent spread of Covid-19 disease, sanitization of workplaces using sodium hypochlorite (NaOCl) disinfectant is one of the several precautionary steps that are followed currently. ... ...

Abstract	World is fighting Covid-19 pandemic since beginning of the year 2020. To prevent spread of Covid-19 disease, sanitization of workplaces using sodium hypochlorite (NaOCl) disinfectant is one of the several precautionary steps that are followed currently. In this letter, I share an experience wherein regular spraying of NaOCl solution in metal forming section of an organization led to development of corrosion damage and rejection of a large number of aircraft structural components made of Al-2024 alloy sheet material.
Language	English
Publishing date	2020-11-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	2364818-1
ISSN	1864-1245 ; 1547-7029
ISSN (online)	1864-1245
ISSN	1547-7029
DOI	10.1007/s11668-020-01082-7
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Article ; Online: Design and Synthesis of Metalloporphyrin Nanoconjugates for Dual Light-Responsive Antimicrobial Photodynamic Therapy.

Pujari, Anil Kumar / Kaur, Ravneet / Reddy, Yeddula Nikhileshwar / Paul, Shatabdi / Gogde, Kunal / Bhaumik, Jayeeta

Journal of medicinal chemistry

2024 Volume 67, Issue 3, Page(s) 2004–2018

Abstract: Antimicrobial photodynamic therapy (APDT) utilizes photosensitizers (PSs) that eradicate a broad spectrum of bacteria in the presence of light and molecular oxygen. On the other hand, some light sources such as ultraviolet (UVB and UVC) have poor ... ...

Abstract	Antimicrobial photodynamic therapy (APDT) utilizes photosensitizers (PSs) that eradicate a broad spectrum of bacteria in the presence of light and molecular oxygen. On the other hand, some light sources such as ultraviolet (UVB and UVC) have poor penetration and high cytotoxicity, leading to undesired PDT of the PSs. Herein, we have synthesized conjugatable mesosubstituted porphyrins and extensively characterized them. Time-dependent density functional theory (TD-DFT) calculations revealed that metalloporphyrin
MeSH term(s)	Photochemotherapy ; Nanoconjugates/chemistry ; Metalloporphyrins/pharmacology ; Photosensitizing Agents/pharmacology ; Photosensitizing Agents/therapeutic use ; Photosensitizing Agents/chemistry ; Anti-Infective Agents
Chemical Substances	Nanoconjugates ; Metalloporphyrins ; Photosensitizing Agents ; Anti-Infective Agents
Language	English
Publishing date	2024-01-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	218133-2
ISSN	1520-4804 ; 0022-2623
ISSN (online)	1520-4804
ISSN	0022-2623
DOI	10.1021/acs.jmedchem.3c01841
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Article ; Online: Stable and luminescent cesium copper halide nanocrystals embedded in flexible polymer fibers for fabrication of down-converting WLEDs.

Kar, Manav Raj / Sahoo, Kajol / Mohapatra, Ashutosh / Bhaumik, Saikat

Nanoscale advances

2023 Volume 5, Issue 22, Page(s) 6238–6248

Abstract: Recently, ... ...

Abstract	Recently, CsPbX
Language	English
Publishing date	2023-10-10
Publishing country	England
Document type	Journal Article
ISSN	2516-0230
ISSN (online)	2516-0230
DOI	10.1039/d3na00440f
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Article ; Online: Tracking an Underwater Object with Unknown Sensor Noise Covariance Using Orthogonal Polynomial Filters.

Kumar, Kundan / Bhaumik, Shovan / Arulampalam, Sanjeev

Sensors (Basel, Switzerland)

2022 Volume 22, Issue 13

Abstract: ... tracking scenarios which consider a nearly constant velocity target. The filter's efficacy is evaluated ...

Abstract	In this manuscript, an underwater target tracking problem with passive sensors is considered. The measurements used to track the target trajectories are (i) only bearing angles, and (ii) Doppler-shifted frequencies and bearing angles. Measurement noise is assumed to follow a zero mean Gaussian probability density function with unknown noise covariance. A method is developed which can estimate the position and velocity of the target along with the unknown measurement noise covariance at each time step. The proposed estimator linearises the nonlinear measurement using an orthogonal polynomial of first order, and the coefficients of the polynomial are evaluated using numerical integration. The unknown sensor noise covariance is estimated online from residual measurements. Compared to available adaptive sigma point filters, it is free from the Cholesky decomposition error. The developed method is applied to two underwater tracking scenarios which consider a nearly constant velocity target. The filter's efficacy is evaluated using (i) root mean square error (RMSE), (ii) percentage of track loss, (iii) normalised (state) estimation error squared (NEES), (iv) bias norm, and (v) floating point operations (flops) count. From the simulation results, it is observed that the proposed method tracks the target in both scenarios, even for the unknown and time-varying measurement noise covariance case. Furthermore, the tracking accuracy increases with the incorporation of Doppler frequency measurements. The performance of the proposed method is comparable to the adaptive deterministic support point filters, with the advantage of a considerably reduced flops requirement.
Language	English
Publishing date	2022-06-30
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2052857-7
ISSN	1424-8220 ; 1424-8220
ISSN (online)	1424-8220
ISSN	1424-8220
DOI	10.3390/s22134970
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Article ; Online: Salience Network Functional Connectivity Mediates Association Between Social Engagement and Cognition in Non-Demented Older Adults: Exploratory Investigation.

Pruitt, Patrick J / Damoiseaux, Jessica S / Hampstead, Benjamin M / Peltier, Scott J / Bhaumik, Arijit K / Albin, Roger L / Dodge, Hiroko H

Journal of Alzheimer's disease reports

2024 Volume 8, Issue 1, Page(s) 531–542

Abstract: ... 7; 84 women) completed the Lubben Social Network Scale 6 (LSNS-6), National Alzheimer's Coordinating ...

Abstract	Background: Social engagement has beneficial effects during cognitive aging. Large-scale cognitive brain network functions are implicated in both social behaviors and cognition. Objective: We evaluated associations between functional connectivity (FC) of large-scale brain cognitive networks and social engagement, characterized by self-reported social network size and contact frequency. We subsequently tested large-scale brain network FC as a potential mediator of the beneficial relationship between social engagement and cognitive performance. Methods: 112 older adults (70.7±7.3 years, range 54.6-89.7; 84 women) completed the Lubben Social Network Scale 6 (LSNS-6), National Alzheimer's Coordinating Center (NACC) Uniform Data Set 3 (UDS-3) cognitive battery, and resting state fMRI. We completed seed-based correlational analysis in the default mode and salience networks. Significant associations between social engagement scores and cognitive performance, as well as between social engagement and FC of brain networks, informed the construction of mediation models. Results: Social engagement was significantly associated with executive function and global cognition, with greater social engagement associated with better cognitive performance. Social engagement was significantly associated with salience network FC, with greater social engagement associated with higher connectivity. Salience network FC partially mediated associations between social engagement and both executive function and global cognition. Conclusions: Our results suggest that the salience network is a key mediator of the beneficial relationship between social engagement and cognition in older adults.
Language	English
Publishing date	2024-03-19
Publishing country	Netherlands
Document type	Journal Article
ISSN	2542-4823
ISSN (online)	2542-4823
DOI	10.3233/ADR-220082
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Article ; Online: Quo Vadis Carbanionic Polymerization?

Ntetsikas, Konstantinos / Ladelta, Viko / Bhaumik, Saibal / Hadjichristidis, Nikos

ACS polymers Au

2022 Volume 3, Issue 2, Page(s) 158–181

Abstract: Living anionic polymerization will soon celebrate 70 years of existence. This living polymerization is considered the mother of all living and controlled/living polymerizations since it paved the way for their discovery. It provides methodologies for ... ...

Abstract	Living anionic polymerization will soon celebrate 70 years of existence. This living polymerization is considered the mother of all living and controlled/living polymerizations since it paved the way for their discovery. It provides methodologies for synthesizing polymers with absolute control of the essential parameters that affect polymer properties, including molecular weight, molecular weight distribution, composition and microstructure, chain-end/in-chain functionality, and architecture. This precise control of living anionic polymerization generated tremendous fundamental and industrial research activities, developing numerous important commodity and specialty polymers. In this Perspective, we present the high importance of living anionic polymerization of vinyl monomers by providing some examples of its significant achievements, presenting its current status, giving several insights into where it is going (Quo Vadis) and what the future holds for this powerful synthetic method. Furthermore, we attempt to explore its advantages and disadvantages compared to controlled/living radical polymerizations, the main competitors of living carbanionic polymerization.
Language	English
Publishing date	2022-12-22
Publishing country	United States
Document type	Journal Article ; Review
ISSN	2694-2453
ISSN (online)	2694-2453
DOI	10.1021/acspolymersau.2c00058
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Book ; Online: Tracking an Underwater Target with Unknown Measurement Noise Statistics Using Variational Bayesian Filters

Das, Shreya / Kumar, Kundan / Bhaumik, Shovan

2023

Abstract: This paper considers a bearings-only tracking problem using noisy measurements of unknown noise statistics from a passive sensor. It is assumed that the process and measurement noise follows the Gaussian distribution where the measurement noise has an ... ...

Abstract	This paper considers a bearings-only tracking problem using noisy measurements of unknown noise statistics from a passive sensor. It is assumed that the process and measurement noise follows the Gaussian distribution where the measurement noise has an unknown non-zero mean and unknown covariance. Here an adaptive nonlinear filtering technique is proposed where the joint distribution of the measurement noise mean and its covariance are considered to be following normal inverse Wishart distribution (NIW). Using the variational Bayesian (VB) method the estimation technique is derived with optimized tuning parameters i.e, the confidence parameter and the initial degree of freedom of the measurement noise mean and the covariance, respectively. The proposed filtering technique is compared with the adaptive filtering techniques based on maximum likelihood and maximum aposteriori in terms of root mean square error in position and velocity, bias norm, average normalized estimation error squared, percentage of track loss, and relative execution time. Both adaptive filtering techniques are implemented using the traditional Gaussian approximate filters and are applied to a bearings-only tracking problem illustrated with moderately nonlinear and highly nonlinear scenarios to track a target following a nearly straight line path. Two cases are considered for each scenario, one when the measurement noise covariance is static and another when the measurement noise covariance is varying linearly with the distance between the target and the ownship. In this work, the proposed adaptive filters using the VB approach are found to be superior to their corresponding adaptive filters based on the maximum aposteriori and the maximum likelihood at the expense of higher computation cost. Comment: 24 pages, 26 figures
Keywords	Electrical Engineering and Systems Science - Signal Processing ; Electrical Engineering and Systems Science - Systems and Control
Subject code	310
Publishing date	2023-05-15
Publishing country	us
Document type	Book ; Online
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Article ; Online: Understanding the charge transfer mechanism in CsPbBr

Ray, Smaranika / Sahoo, Mihir Ranjan / Mukherjee, Susmita / Perumal, Ajay / Nayak, Saroj K / Bhaumik, Saikat

RSC advances

2023 Volume 13, Issue 50, Page(s) 35551–35561

Abstract: Recently, lead halide perovskite nanocrystal (NC)-based heterostructures have demonstrated significant promise in various research areas, including solar cells, ... ...

Abstract	Recently, lead halide perovskite nanocrystal (NC)-based heterostructures have demonstrated significant promise in various research areas, including solar cells, CO
Language	English
Publishing date	2023-12-06
Publishing country	England
Document type	Journal Article
ISSN	2046-2069
ISSN (online)	2046-2069
DOI	10.1039/d3ra06307k
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Article ; Online: MAL expression downregulation through suppressive H3K27me3 marks at the promoter in HPV16-related cervical cancers is prognostically relevant and manifested by the interplay of novel MAL antisense long noncoding RNA AC103563.8, E7 oncoprotein and EZH2.

Sinha, Abarna / Ghosh, Abhisikta / Ghosh, Arnab / Mathai, Sonia / Bhaumik, Jaydip / Mukhopadhyay, Asima / Maitra, Arindam / Biswas, Nidhan K / Sengupta, Sharmila

Clinical epigenetics

2024 Volume 16, Issue 1, Page(s) 40

Abstract: Background: MAL (T-lymphocyte maturation-associated protein) is highly downregulated in most cancers, including cervical cancer (CaCx), attributable to promoter hypermethylation. Long noncoding RNA genes (lncGs) play pivotal roles in CaCx pathogenesis, ... ...

Abstract	Background: MAL (T-lymphocyte maturation-associated protein) is highly downregulated in most cancers, including cervical cancer (CaCx), attributable to promoter hypermethylation. Long noncoding RNA genes (lncGs) play pivotal roles in CaCx pathogenesis, by interacting with human papillomavirus (HPV)-encoded oncoproteins, and epigenetically regulating coding gene expression. Hence, we attempted to decipher the impact and underlying mechanisms of MAL downregulation in HPV16-related CaCx pathogenesis, by interrogating the interactive roles of MAL antisense lncRNA AC103563.8, E7 oncoprotein and PRC2 complex protein, EZH2. Results: Employing strand-specific RNA-sequencing, we confirmed the downregulated expression of MAL in association with poor overall survival of CaCx patients bearing HPV16, along with its antisense long noncoding RNA (lncRNA) AC103563.8. The strength of positive correlation between MAL and AC103563.8 was significantly high among patients compared to normal individuals. While downregulated expression of MAL was significantly associated with poor overall survival of CaCx patients bearing HPV16, AC103563.8 did not reveal any such association. We confirmed the enrichment of chromatin suppressive mark, H3K27me3 at MAL promoter, using ChIP-qPCR in HPV16-positive SiHa cells. Subsequent E7 knockdown in such cells significantly increased MAL expression, concomitant with decreased EZH2 expression and H3K27me3 marks at MAL promoter. In silico analysis revealed that both E7 and EZH2 bear the potential of interacting with AC103563.8, at the same binding domain. RNA immunoprecipitation with anti-EZH2 and anti-E7 antibodies, respectively, and subsequent quantitative PCR analysis in E7-silenced and unperturbed SiHa cells confirmed the interaction of AC103563.8 with EZH2 and E7, respectively. Apparently, AC103563.8 seems to preclude EZH2 and bind with E7, failing to block EZH2 function in patients. Thereby, enhanced EZH2 expression in the presence of E7 could potentially inactivate the MAL promoter through H3K27me3 marks, corroborating our previous results of MAL expression downregulation in patients. Conclusion: AC103563.8-E7-EZH2 axis, therefore, appears to crucially regulate the expression of MAL, through chromatin inactivation in HPV16-CaCx pathogenesis, warranting therapeutic strategy development.
MeSH term(s)	Female ; Humans ; Chromatin/metabolism ; DNA Methylation ; Down-Regulation ; Enhancer of Zeste Homolog 2 Protein/genetics ; Enhancer of Zeste Homolog 2 Protein/metabolism ; Histones/metabolism ; Human papillomavirus 16/genetics ; Oncogene Proteins, Viral/genetics ; Oncogene Proteins, Viral/metabolism ; Papillomavirus E7 Proteins/genetics ; Papillomavirus E7 Proteins/metabolism ; RNA, Long Noncoding/genetics ; RNA, Long Noncoding/metabolism ; Uterine Cervical Neoplasms/pathology ; Myelin and Lymphocyte-Associated Proteolipid Proteins/genetics ; Myelin and Lymphocyte-Associated Proteolipid Proteins/metabolism
Chemical Substances	Chromatin ; Enhancer of Zeste Homolog 2 Protein (EC 2.1.1.43) ; EZH2 protein, human (EC 2.1.1.43) ; Histones ; Oncogene Proteins, Viral ; Papillomavirus E7 Proteins ; RNA, Long Noncoding ; MAL protein, human ; Myelin and Lymphocyte-Associated Proteolipid Proteins
Language	English
Publishing date	2024-03-10
Publishing country	Germany
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2553921-8
ISSN	1868-7083 ; 1868-7075
ISSN (online)	1868-7083
ISSN	1868-7075
DOI	10.1186/s13148-024-01651-9
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Article ; Online: The Emerging Roles of Silver Nanoparticles to Target Viral Life Cycle and Detect Viral Pathogens.

Ghosh, Ujjyani / Sayef Ahammed, Khondakar / Mishra, Snehasis / Bhaumik, Asim

Chemistry, an Asian journal

2022 Volume 17, Issue 5, Page(s) e202101149

Abstract: Along the line of recent vaccine advancements, new antiviral therapeutics are compelling to combat viral infection-related public health crises. Several properties of silver nanoparticles (AgNPs) such as low level of cytotoxicity, ease of tunability of ... ...

Abstract	Along the line of recent vaccine advancements, new antiviral therapeutics are compelling to combat viral infection-related public health crises. Several properties of silver nanoparticles (AgNPs) such as low level of cytotoxicity, ease of tunability of the AgNPs in the ultra-small nanoscale size and shape through different convenient bottom-up chemistry approaches, high penetration of the composite with drug formulations into host cells has made AgNPs, a promising candidate for developing antivirals. In this review, we have highlighted the recent advancements in the AgNPs based nano-formulations to target cellular mechanisms of viral propagation, immune modulation of the host, and the ability to synergistically enhance the activity of existing antiviral drugs. On the other hand, we have discussed the recent advancements on AgNPs based detection of viral pathogens from clinical samples using inherent physicochemical properties. This article will provide an overview of our current knowledge on AgNPs based formulations that has promising potential for developing a counteractive strategy against emerging and existing viruses.
MeSH term(s)	Animals ; Antiviral Agents/chemistry ; Antiviral Agents/pharmacology ; Life Cycle Stages ; Metal Nanoparticles/chemistry ; Silver/chemistry ; Silver/pharmacology
Chemical Substances	Antiviral Agents ; Silver (3M4G523W1G)
Language	English
Publishing date	2022-01-24
Publishing country	Germany
Document type	Journal Article ; Review
ZDB-ID	2233006-9
ISSN	1861-471X ; 1861-4728
ISSN (online)	1861-471X
ISSN	1861-4728
DOI	10.1002/asia.202101149
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