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  1. Book ; Online: The Parallel March of Asthma and Allergy in Childhood: A Multi-Perspective Approach

    Caffarelli, Carlo / Priftis, Kostas N. / Garcia-Marcos, Luis

    2018  

    Abstract: It has not been yet clarified whether allergy and asthma are part of the same condition or they follow a parallel path. This Research Topic aims to try and put some light in this parallel march going through crucial topics: from prenatal events to later ... ...

    Abstract It has not been yet clarified whether allergy and asthma are part of the same condition or they follow a parallel path. This Research Topic aims to try and put some light in this parallel march going through crucial topics: from prenatal events to later risk factors such as obesity; and from basic immunology to immunotherapy, both subcutaneous and sublingual. We hope the readers can infer their own conclusions as what is first: egg or chicken
    Keywords Medicine (General) ; Pediatrics
    Size 1 electronic resource (152 p.)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020101843
    ISBN 9782889455294 ; 2889455297
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article: Inhaled Short-Acting Beta Agonist Treatment-Associated Supraventricular Tachycardia in Children: Still a Matter of Concern in Pediatric Emergency Departments?

    Tchana, Bertrand / Caffarelli, Carlo

    Children (Basel, Switzerland)

    2023  Volume 10, Issue 4

    Abstract: Inhaled selective short-acting β-2 agonists (SABA), such as salbutamol, are the rescue treatment of choice for the relief of symptoms of acute asthma exacerbations: one of the leading causes of pediatric emergency department admission and hospitalization. ...

    Abstract Inhaled selective short-acting β-2 agonists (SABA), such as salbutamol, are the rescue treatment of choice for the relief of symptoms of acute asthma exacerbations: one of the leading causes of pediatric emergency department admission and hospitalization. Cardiovascular events, including supraventricular arrhythmias, are the most frequent side effects reported with inhaled SABA in children with asthma and are the main reason for a continuing debate about their safety, despite their widespread use. Although supraventricular tachycardia (SVT) is the most common potentially serious dysrhythmia in children, the incidence and risk factor of SVT after SABA administration is currently unknown. We here reported three cases and conducted a review of the literature in an attempt to gain insight into this issue.
    Language English
    Publishing date 2023-04-08
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2732685-8
    ISSN 2227-9067
    ISSN 2227-9067
    DOI 10.3390/children10040699
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Year 2022: exploring COVID-19 pandemic in children.

    Bozzola, Elena / Caffarelli, Carlo / Santamaria, Francesca / Corsello, Giovanni

    Italian journal of pediatrics

    2023  Volume 49, Issue 1, Page(s) 128

    Abstract: COVID-19 pandemics is rapidly changing. In this article, we review progresses published in the Italian Journal of Pediatrics in 2022. More data on clinical pictures, prevention strategies and active management in children have been provided. The ... ...

    Abstract COVID-19 pandemics is rapidly changing. In this article, we review progresses published in the Italian Journal of Pediatrics in 2022. More data on clinical pictures, prevention strategies and active management in children have been provided. The continued evolution of knowledge has driven transformations in the clinical approach to the disease and allowed key advancements in the care of children with COVID-19.
    MeSH term(s) Child ; Humans ; COVID-19/epidemiology ; SARS-CoV-2 ; Pandemics/prevention & control ; Italy/epidemiology
    Language English
    Publishing date 2023-09-29
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2088556-8
    ISSN 1824-7288 ; 1720-8424
    ISSN (online) 1824-7288
    ISSN 1720-8424
    DOI 10.1186/s13052-023-01536-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1961: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: Anti-inflammatory and biologic drugs for atopic dermatitis: a therapeutic approach in children and adolescents.

    Caffarelli, Carlo / Giannetti, Arianna / Giannì, Giuliana / Ricci, Giampaolo

    Frontiers in medicine

    2023  Volume 10, Page(s) 1214963

    Abstract: Atopic dermatitis (AD) is a chronic inflammatory disease with a heterogeneous pathogenesis correlated with dysregulation of the immune system and a prevalence of the T2-mediated immune pathway. Recent understanding of the pathogenesis of AD has allowed ... ...

    Abstract Atopic dermatitis (AD) is a chronic inflammatory disease with a heterogeneous pathogenesis correlated with dysregulation of the immune system and a prevalence of the T2-mediated immune pathway. Recent understanding of the pathogenesis of AD has allowed the development of new drugs targeting different mechanisms and cytokines that have changed the treatment approach. The aim of this review is to update knowledge on the standard of care and recent advancements in the control of skin inflammation. In light of recent guidelines, we report on the clinical efficacy of novel treatments, with special attention to situations where biologics and small molecules are involved.
    Language English
    Publishing date 2023-08-16
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2023.1214963
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Are Babies Born Preterm High-Risk Asthma Candidates?

    Caffarelli, Carlo / Gracci, Serena / Giannì, Giuliana / Bernardini, Roberto

    Journal of clinical medicine

    2023  Volume 12, Issue 16

    Abstract: Among preterm infants, the risk of developing asthma is a matter of debate. This review discusses the state of the art of poorly understood prematurity-associated asthma. Impaired pulmonary function is common in children born prematurely. Preterm infants ...

    Abstract Among preterm infants, the risk of developing asthma is a matter of debate. This review discusses the state of the art of poorly understood prematurity-associated asthma. Impaired pulmonary function is common in children born prematurely. Preterm infants are prone to developing viral respiratory tract infections, bronchiolitis in the first year of life, and recurrent viral wheezing in preschool age. All of these conditions may precede asthma development. We also discuss the role of both atopic sensitization and intestinal microbiome and, consequently, immune maturation. Diet and pollution have been considered to better understand how prematurity could be associated with asthma. Understanding the effect of factors involved in asthma onset may pave the way to improve the prediction of this asthma phenotype.
    Language English
    Publishing date 2023-08-19
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12165400
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The year 2021 in COVID-19 pandemic in children.

    Bozzola, Elena / Caffarelli, Carlo / Santamaria, Francesca / Corsello, Giovanni

    Italian journal of pediatrics

    2022  Volume 48, Issue 1, Page(s) 161

    Abstract: In this article, the developments in the field of COVID-19 pandemic published in the Italian Journal of Pediatrics in 2021 are reflected. We describe progresses in SARS-CoV-2 transmission route, clinical presentation, diagnosis, treatment, and access to ... ...

    Abstract In this article, the developments in the field of COVID-19 pandemic published in the Italian Journal of Pediatrics in 2021 are reflected. We describe progresses in SARS-CoV-2 transmission route, clinical presentation, diagnosis, treatment, and access to health care facilities in children. They led to substantial changes in the clinical approach.
    MeSH term(s) COVID-19/epidemiology ; Child ; Humans ; Pandemics ; SARS-CoV-2
    Language English
    Publishing date 2022-09-05
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2088556-8
    ISSN 1824-7288 ; 1720-8424
    ISSN (online) 1824-7288
    ISSN 1720-8424
    DOI 10.1186/s13052-022-01360-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1961: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Natural History of Hazelnut Allergy and Current Approach to Its Diagnosis and Treatment.

    Giannetti, Arianna / Ruggi, Alessandro / Ricci, Giampaolo / Giannì, Giuliana / Caffarelli, Carlo

    Children (Basel, Switzerland)

    2023  Volume 10, Issue 3

    Abstract: Hazelnut allergy is the most prevalent type of nut allergy in Europe, with symptoms that can range from mild, such as hives and itching, to severe, such as anaphylaxis, particularly in patients who are sensitized to highly stable allergens, such as ... ...

    Abstract Hazelnut allergy is the most prevalent type of nut allergy in Europe, with symptoms that can range from mild, such as hives and itching, to severe, such as anaphylaxis, particularly in patients who are sensitized to highly stable allergens, such as storage proteins. Compared to other types of food allergies, allergies to tree nuts, including hazelnuts, tend to persist throughout life. Although symptoms can appear in early childhood, they often continue into adulthood, with a minority of cases improving during adolescence. Currently, there is no curative treatment available for hazelnut allergy, and patients must adhere to a restrictive diet and carry autoinjective epinephrine. However, oral allergen immunotherapy (AIT) is a promising treatment option. Patients can be categorized based on their risk for severe reactions using various clinical, in vivo, and in vitro tests, including component-resolved diagnosis and oral food challenge. This review aims to provide an overview of the current knowledge of the natural history of hazelnut allergy and new approaches for its diagnosis and management.
    Language English
    Publishing date 2023-03-18
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2732685-8
    ISSN 2227-9067
    ISSN 2227-9067
    DOI 10.3390/children10030585
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Egg Allergy in Children and Weaning Diet.

    Caffarelli, Carlo / Giannetti, Arianna / Rossi, Arianna / Ricci, Giampaolo

    Nutrients

    2022  Volume 14, Issue 8

    Abstract: Eggs are a fundamental food in the human diet, and together with cow's milk, they are the most common food allergen. This work highlights the main nutritional characteristics of eggs to show how their absence from a child's diet can constitute a serious ... ...

    Abstract Eggs are a fundamental food in the human diet, and together with cow's milk, they are the most common food allergen. This work highlights the main nutritional characteristics of eggs to show how their absence from a child's diet can constitute a serious deficiency. We then analyze the risk factors that facilitate the onset of egg allergy. The third part of the paper reports possible interventions to lower the appearance of food allergy that have been occurred in trials. The last part of the paper is a synthesis of this research study that has been taken from several of the latest guidelines or from position papers.
    MeSH term(s) Allergens ; Animals ; Cattle ; Diet ; Egg Hypersensitivity ; Eggs/adverse effects ; Female ; Food Hypersensitivity/prevention & control ; Humans ; Infant ; Milk Hypersensitivity ; Weaning
    Chemical Substances Allergens
    Language English
    Publishing date 2022-04-07
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu14081540
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: IgE Mediated Shellfish Allergy in Children-A Review.

    Giannetti, Arianna / Pession, Andrea / Bettini, Irene / Ricci, Giampaolo / Giannì, Giuliana / Caffarelli, Carlo

    Nutrients

    2023  Volume 15, Issue 14

    Abstract: Shellfish is a leading cause of food allergy and anaphylaxis worldwide. Recent advances in molecular characterization have led to a better understanding of the allergen profile. High sequence homology between shellfish species and between shellfish and ... ...

    Abstract Shellfish is a leading cause of food allergy and anaphylaxis worldwide. Recent advances in molecular characterization have led to a better understanding of the allergen profile. High sequence homology between shellfish species and between shellfish and house dust mites leads to a high serological cross-reactivity, which does not accurately correlate with clinical cross-reactions. Clinical manifestations are immediate and the predominance of perioral symptoms is a typical feature of shellfish allergy. Diagnosis, as for other food allergies, is based on SPTs and specific IgE, while the gold standard is DBPCFC. Cross-reactivity between shellfish is common and therefore, it is mandatory to avoid all shellfish. New immunotherapeutic strategies based on hypoallergens and other innovative approaches represent the new frontiers for desensitization.
    MeSH term(s) Humans ; Child ; Shellfish Hypersensitivity/diagnosis ; Immunoglobulin E ; Shellfish ; Food Hypersensitivity/diagnosis ; Food Hypersensitivity/therapy ; Seafood ; Allergens
    Chemical Substances Immunoglobulin E (37341-29-0) ; Allergens
    Language English
    Publishing date 2023-07-12
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15143112
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Fish Allergy and Related Conditions in Children: A Review.

    Giannetti, Arianna / Bettini, Irene / Alfieri, Eleonora / De Bona, Amina / Giannì, Giuliana / Ricci, Giampaolo / Caffarelli, Carlo

    Current pediatric reviews

    2024  Volume 20, Issue 3, Page(s) 224–239

    Abstract: Fish allergy is the important food allergies in childhood, often persisting into adulthood. It can cause severe hypersensitivity reactions, including fatal anaphylaxis; furthermore, avoiding-fish diet has negative nutritional and psychological effects. ... ...

    Abstract Fish allergy is the important food allergies in childhood, often persisting into adulthood. It can cause severe hypersensitivity reactions, including fatal anaphylaxis; furthermore, avoiding-fish diet has negative nutritional and psychological effects. Recent research studies focus on epitope structures and aim to develop sensitive and specific diagnostic tools, which have a better correlation with clinical reactions. Protocols with hypoallergenic parvalbumin or other recombinant antigens are also under study and will likely lead to new immunotherapy protocols. IgE-mediated fish allergy differs substantially from other forms of immunological adverse reactions to fish, such as Food Protein-Induced Enterocolitis Syndrome and eosinophilic esophagitis. In addition, fish ingestion can cause non-immunological adverse reactions, such as in the case of scombroid poisoning, anisakiasis and toxic poisoning. This review aims to summarize the characteristics of the main immunological and non-immunological fish reactions, analyzing the epidemiology, clinical manifestations, diagnosis and therapy, with a particular focus on clinical management.
    MeSH term(s) Child ; Humans ; Allergens ; Anaphylaxis/diagnosis ; Anaphylaxis/etiology ; Anaphylaxis/therapy ; Eosinophilic Esophagitis ; Food Hypersensitivity/diagnosis ; Food Hypersensitivity/therapy ; Food Hypersensitivity/etiology ; Seafood/adverse effects
    Chemical Substances Allergens
    Language English
    Publishing date 2024-02-07
    Publishing country United Arab Emirates
    Document type Review ; Journal Article
    ISSN 1875-6336
    ISSN (online) 1875-6336
    DOI 10.2174/0115733963267330230919094037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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