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  1. Book ; Thesis: Auswertung der Aeromedical Evacuation-Flüge der Deutschen Bundeswehr im Rahmen der COVID-19-Pandemie

    Post, Janina / Hachenberg, Thomas / Rose, Dirk-Matthias

    2021  

    Institution Otto-von-Guericke-Universität Magdeburg
    Author's details vorgelegt von Janina Post
    Language German
    Size VI, 74 Blätter, Illustrationen, Diagramme, 31 cm
    Publishing place Magdeburg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Otto-von-Guericke-Universität Magdeburg, 2021
    HBZ-ID HT021740829
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Physiological Mechanisms That Impact Exercise Adaptations for Individuals With Down Syndrome.

    Post, Emily M / Kraemer, William J

    Journal of strength and conditioning research

    2023  Volume 37, Issue 12, Page(s) e646–e655

    Abstract: ... for individuals with Down syndrome. J Strength Cond Res 37(12): e646-e655, 2023-Down syndrome (DS) is the most ... Abstract: Post, EM, and Kraemer, WJ. Physiological mechanisms that impact exercise adaptations ...

    Abstract Abstract: Post, EM, and Kraemer, WJ. Physiological mechanisms that impact exercise adaptations for individuals with Down syndrome. J Strength Cond Res 37(12): e646-e655, 2023-Down syndrome (DS) is the most common chromosomal disorder diagnosed in the United States since 2014. There is a wide range of intellectual severities, with the average IQ of individuals with DS at approximately 50 and adults without intellectual delay at approximately 70-130. Individuals with DS vary from mild to severe cognitive impairment, depending on the phenotypic penetration on the 21st chromosome, with the average cognitive capacity equivalent to a cognitive functioning of an 8- to 9-year-old child. To have successful health, all aspects of health must be considered (i.e., overall health, fitness, and social). Both aerobic training and resistance training (RT) are favored for a healthy lifestyle. Resistance training specifically can help improve motor function and overall activities of daily living. Although many motivational and environmental barriers for individuals with DS can make exercising difficult, there are many ways to overcome those barriers (both intrinsically and extrinsically). Individuals with DS should strive for 150 minutes of moderate-intensity or 75 minutes of vigorous-intensity aerobic exercise a week or a combination of both. The individual should also strive for 2 or more days a week of strengthening activities, such as RT, involving all muscle groups. These activities will help improve many aspects of life, leading to a better quality of life. Regular group exercise activity can help increase self-confidence and success socially in life. This review will focus on the underlying biological mechanisms related to DS, their influence on exercise, and the roles exercise plays in mediating positive health, physical fitness, and social lifestyle outcomes.
    MeSH term(s) Adult ; Child ; Humans ; Quality of Life ; Down Syndrome ; Activities of Daily Living ; Exercise ; Physical Fitness
    Language English
    Publishing date 2023-11-28
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 1156349-7
    ISSN 1533-4287 ; 1064-8011
    ISSN (online) 1533-4287
    ISSN 1064-8011
    DOI 10.1519/JSC.0000000000004658
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Online: Analyse extra beschikbaar voedsel bij vervanging veevoergewassen op akkerland door voedselgewassen

    Conijn, J.G. / Post, P.M.

    2023  

    Abstract: Dit rapport bevat de resultaten van een ‘quick-scan’ analyse naar extra voedselbeschikbaarheid indien veevoergewassen op akkerland vervangen zouden worden door voedselgewassen die direct geschikt zijn voor humane consumptie. Het akkerlandareaal dat ... ...

    Abstract Dit rapport bevat de resultaten van een ‘quick-scan’ analyse naar extra voedselbeschikbaarheid indien veevoergewassen op akkerland vervangen zouden worden door voedselgewassen die direct geschikt zijn voor humane consumptie. Het akkerlandareaal dat mondiaal gebruikt werd voor de teelt van voedselgewassen, loopt uiteen van 350 tot 600 miljoen ha. Nederland droeg minder dan 1% bij aan dit mondiale totaal. De extra hoeveelheid calorieën die mondiaal geproduceerd kan worden in humaan voedsel, varieerde van +33 tot +60% ten opzichte van huidige situatie. De extra calorieën in humaan voedsel zijn ook geschat voor 20 hoofdregio’s in de wereld. Per regio zijn deze extra calorieën vergeleken met de netto- import en gebruikt voor de berekening van een indicator die de mate van ondervoeding in een regio aangeeft.
    Keywords Life Science
    Language Dutch
    Publisher Stichting Wageningen Research, Wageningen Plant Research, Business unit Agrosysteemkunde
    Publishing country nl
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Investigating the Role of Metabolism for Antibiotic Combination Therapies in

    Golden, Martina M / Post, Savannah J / Rivera, Renata / Wuest, William M

    ACS infectious diseases

    2023  Volume 9, Issue 12, Page(s) 2386–2393

    Abstract: Antibacterial resistance poses a severe threat to public health; an anticipated 14-fold increase in multidrug-resistant (MDR) bacterial infections is expected to occur by 2050. Contrary to antibiotics, combination therapies are the standard of care for ... ...

    Abstract Antibacterial resistance poses a severe threat to public health; an anticipated 14-fold increase in multidrug-resistant (MDR) bacterial infections is expected to occur by 2050. Contrary to antibiotics, combination therapies are the standard of care for antiviral and anticancer treatments, as synergistic drug-drug interactions can decrease dosage and resistance development. In this study, we investigated combination treatments of a novel succinate dehydrogenase inhibitor (promysalin) with specific inhibitors of metabolism and efflux alongside a panel of clinically approved antibiotics in synergy studies. Through these investigations, we determined that promysalin can work synergistically with vancomycin and antagonistically with aminoglycosides and a glyoxylate shunt pathway inhibitor at subinhibitory concentrations; however, these cooperative effects do not reduce minimum inhibitory concentrations. The variability of these results underscores the complexity of targeting metabolism for combination therapies in antibiotic development.
    MeSH term(s) Humans ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Pseudomonas aeruginosa ; Pyrrolidines/pharmacology ; Salicylamides/pharmacology ; Pseudomonas Infections/drug therapy
    Chemical Substances Anti-Bacterial Agents ; promysalin ; Pyrrolidines ; Salicylamides
    Language English
    Publishing date 2023-11-08
    Publishing country United States
    Document type Journal Article
    ISSN 2373-8227
    ISSN (online) 2373-8227
    DOI 10.1021/acsinfecdis.3c00452
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Total Synthesis of the Reported Structure of Cahuitamycin A: Insights into an Elusive Natural Product Scaffold.

    Shapiro, Justin A / Post, Savannah J / Smith, Gavin C / Wuest, William M

    Organic letters

    2023  Volume 25, Issue 51, Page(s) 9243–9248

    Abstract: In a 2016 screen of natural product extracts, a new family of natural products, the cahuitamycins, was discovered and found to inhibit biofilm formation in the human ... ...

    Abstract In a 2016 screen of natural product extracts, a new family of natural products, the cahuitamycins, was discovered and found to inhibit biofilm formation in the human pathogen
    MeSH term(s) Humans ; Biological Products/chemistry ; Molecular Structure ; Isomerism ; Stereoisomerism ; Acinetobacter baumannii
    Chemical Substances Biological Products
    Language English
    Publishing date 2023-12-18
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ISSN 1523-7052
    ISSN (online) 1523-7052
    DOI 10.1021/acs.orglett.3c03993
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Uterine niches and infertility: challenge for the future.

    Klein Meuleman, Saskia J M / Post, Britt / Vissers, Jolijn / de Leeuw, Robert A / Post Uiterweer, Emiel D / Huirne, Judith A F

    Fertility and sterility

    2023  Volume 119, Issue 5, Page(s) 893

    MeSH term(s) Female ; Humans ; Uterus ; Infertility/diagnosis ; Infertility/therapy ; Infertility, Female/diagnosis ; Infertility, Female/therapy
    Language English
    Publishing date 2023-01-31
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80133-1
    ISSN 1556-5653 ; 0015-0282
    ISSN (online) 1556-5653
    ISSN 0015-0282
    DOI 10.1016/j.fertnstert.2023.01.036
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: The effects of a theory-informed intervention on physical activity behaviour, motivation and well-being of frontline aged care workers: A pilot study with 6-month follow-up.

    Lock, Merilyn / Post, Dannielle / Dollman, James / Parfitt, Gaynor

    Health promotion journal of Australia : official journal of Australian Association of Health Promotion Professionals

    2023  Volume 35, Issue 1, Page(s) 207–219

    Abstract: ... Δ 29.11 m ± SE: 13.75; p = .04), which appeared to be driven by the relative autonomy index ... in a single cohort, pre-post pilot trial. The program included a Motivational Interviewing style appointment ...

    Abstract Issue addressed: Due to the nature of their jobs, frontline aged care workers may be a population at risk of poor health and lifestyle habits. Support of their well-being through the workplace is likely to be complex. The objective of this study was to assess the effectiveness of a need-supportive program for changing physical activity and psychological well-being via the motivational processes of behavioural regulations and perceived need satisfaction.
    Methods: Frontline aged care workers (n = 25) participated in a single cohort, pre-post pilot trial. The program included a Motivational Interviewing style appointment, education on goal setting and self-management, the use of affect, exertion and self-pacing for regulating physical activity intensity and practical support activities. Outcomes (7-day accelerometery, 6-min walk, K10 and AQoL-8D), and motivational processes (BREQ-3 and PNSE) were measured at baseline, 3 and 9 months, and analysed using linear mixed models for repeated measures.
    Results: There were significant increases in perceived autonomy at 3 months (Δ .43 ± SE: .20; p = .03) and 6-min walk distance at 9 months (Δ 29.11 m ± SE: 13.75; p = .04), which appeared to be driven by the relative autonomy index (behavioural regulations in exercise questionnaire [BREQ-3]). Amotivation increased at 3 months (Δ .23 ± SE:.12; p = .05); which may have been due to low scores at baseline. No other changes were demonstrated at any timepoint. SO WHAT?: Participants demonstrated positive changes in motivational processes and physical function, however, due to the low levels of participation in the program, the program had a negligible impact at the organisational level. Future researchers and aged care organisations should aim to address factors impacting participation in well-being initiatives.
    MeSH term(s) Humans ; Aged ; Pilot Projects ; Motivation ; Follow-Up Studies ; Motor Activity ; Exercise
    Language English
    Publishing date 2023-05-09
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2250864-8
    ISSN 2201-1617 ; 1036-1073
    ISSN (online) 2201-1617
    ISSN 1036-1073
    DOI 10.1002/hpja.740
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Comparison of machine learning algorithms to predict dissolved oxygen in an urban stream.

    Bolick, Madeleine M / Post, Christopher J / Naser, Mohannad-Zeyad / Mikhailova, Elena A

    Environmental science and pollution research international

    2023  Volume 30, Issue 32, Page(s) 78075–78096

    Abstract: Water quality monitoring for urban watersheds is critical to identify the negative urbanization impacts. This study sought to identify a successful predictive machine learning model with minimal parameters from easy-to-deploy, low-cost sensors to create ... ...

    Abstract Water quality monitoring for urban watersheds is critical to identify the negative urbanization impacts. This study sought to identify a successful predictive machine learning model with minimal parameters from easy-to-deploy, low-cost sensors to create a monitoring system for the urban stream network, Hunnicutt Creek, in Clemson, SC, USA. A multiple linear regression model was compared to machine learning algorithms k-nearest neighbor, decision tree, random forest, and gradient boosting. These algorithms were evaluated to understand which best predicted dissolved oxygen (DO) from water temperature, conductivity, turbidity, and water level change at four locations along the urban stream. The random forest algorithm had the highest performance in predicting DO for all four sites, with Nash-Sutcliffe model efficiency coefficient (NSE) scores > 0.9 at three sites and > 0.598 at the fourth site. The random forest model was further examined using explainable artificial intelligence (XAI) and found that temperature influenced the DO predictions for three of the four sites, but there were different water quality interactions depending on site location. Calculating the land cover type in each site's sub-watershed revealed that different amounts of impervious surface and vegetation influenced water quality and the resulting DO predictions. Overall, machine learning combined with land cover data helps decision-makers better understand the nuances of urban watersheds and the relationships between urban land cover and water quality.
    MeSH term(s) Environmental Monitoring/methods ; Rivers ; Artificial Intelligence ; Oxygen ; Algorithms ; Machine Learning
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2023-06-02
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-023-27481-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Effect of coercive measures on treatment outcome in involuntarily admitted patients in Amsterdam.

    van der Post, L F M / Nusselder, K J / Peen, J / Nabitz, U / Dekker, J M

    Frontiers in psychiatry

    2023  Volume 14, Page(s) 1240129

    Abstract: Objective: The prevalence of involuntary admissions rose the last forty years in European countries, including the Netherlands. Involuntary admissions result in seclusion, physical restraint and forced medication in approximately 40% of patients. We ... ...

    Abstract Objective: The prevalence of involuntary admissions rose the last forty years in European countries, including the Netherlands. Involuntary admissions result in seclusion, physical restraint and forced medication in approximately 40% of patients. We looked at whether treatment outcomes differ in patients with and without coercive measures.
    Methods: Using The Health of the Nation Outcome Scales (HoNOS) to measure treatment outcomes, we studied the files of 786 patients admitted involuntarily to an Amsterdam clinic. We applied Generalised Linear Models to determine whether the use, or not, of coercive measures during treatment was associated with a difference in outcomes.
    Results: 19% of the cohort were secluded in a High Security Room (HSR); 24% were secluded in their own room and/or received forced medication. After adjustment for the influence of diagnosis, disorder severity (initial HoNOS score) and treatment duration, the HSR group had, on average, a HoNOS difference score that was 2.4 points lower than patients without coercive measures (CI -4.0 to -0.8.;
    Conclusion: Seclusion, whether or not in combination with forced medication, was applied to two-fifths of patients. The HoNOS scores of the group without coercion improved by nearly two and a half points more on average than those of the two groups with coercion. A causal relationship between coercion and treatment outcome could neither be confirmed nor excluded on the basis of our results.
    Language English
    Publishing date 2023-09-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2023.1240129
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Non-ammoniagenic proliferation and differentiation media for cultivated adipose tissue.

    Hubalek, S / Melke, J / Pawlica, P / Post, M J / Moutsatsou, P

    Frontiers in bioengineering and biotechnology

    2023  Volume 11, Page(s) 1202165

    Abstract: Ammonia (Amm), and its aqueous solved state, ammonium, which is produced from glutamine (Gln) metabolism, is a known inhibitor of stem cell ... ...

    Abstract Ammonia (Amm), and its aqueous solved state, ammonium, which is produced from glutamine (Gln) metabolism, is a known inhibitor of stem cell proliferation
    Language English
    Publishing date 2023-07-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2719493-0
    ISSN 2296-4185
    ISSN 2296-4185
    DOI 10.3389/fbioe.2023.1202165
    Database MEDical Literature Analysis and Retrieval System OnLINE

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