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  1. Article: A socio-legal analysis of the Belgian protective legislation towards victims of aggravated forms of migrant smuggling.

    de Massol de Rebetz, Roxane / van der Woude, Maartje

    Crime, law, and social change

    2022  Volume 78, Issue 4, Page(s) 357–378

    Abstract: As many scholars have shown, and other than what is suggested by their legal definition, migrant smuggling and human trafficking are not always easily distinguishable in reality. Acknowledging this grey area between the two phenomena, the Belgian ... ...

    Abstract As many scholars have shown, and other than what is suggested by their legal definition, migrant smuggling and human trafficking are not always easily distinguishable in reality. Acknowledging this grey area between the two phenomena, the Belgian legislature has introduced an alternative approach (referred to as 'third-way approach') which would offer migrants who have experienced 'aggravated forms' of migrant smuggling the same protective status that is usually strictly reserved for victims of human trafficking. Interestingly enough, migrants don't seem inclined to make use of this procedure. Through a series of expert interviews, this article shines light on the perspective of key actors within the Belgian criminal justice system and migration control apparatus with regard to this third-way approach and its functioning in practice. In so doing, the article not only reveals how the proper functioning of this third-way approach is hindered by a series of organizational and institutional factors, but it also shows how the different actors are struggling with the inherent tension between the objectives of protecting state security and the protection of the needs of vulnerable groups in precarious life situations.
    Language English
    Publishing date 2022-04-07
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2015096-9
    ISSN 1573-0751 ; 0925-4994
    ISSN (online) 1573-0751
    ISSN 0925-4994
    DOI 10.1007/s10611-022-10029-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Guest Editorial

    Maartje van der Woude / Richard Staring

    International Journal for Crime, Justice and Social Democracy, Vol 10, Iss 3, Pp i-viii (2021)

    Transforming Borders and the Discretionary Politics of Migration Control

    2021  

    Abstract: The eight articles in this issue promise us a global journey around transformed borders, multiscalar bordering, and discretionary practices within these migration controls. In doing so, the authors guide us through the Global North and Global South with ... ...

    Abstract The eight articles in this issue promise us a global journey around transformed borders, multiscalar bordering, and discretionary practices within these migration controls. In doing so, the authors guide us through the Global North and Global South with countries as varied as the US, Mexico, Mali, Poland, Norway, the Netherlands, the United Kingdom (UK), Spain, Italy, Germany, Greece, and Turkey. We also gain insights through these specific research settings from additional Asian and African countries of origin for the migrants involved. By situating their analyses in a specific locus, the authors provide us with a grounded, localized narrative, which they insightfully theorize on and interact with at the global level. Through these glocalized analyses, we not only learn about the importance of multiscalar forms of migration control and the discretion of these actors within these bordering practices, but also gain insights into the immediate and long-term effects of these control efforts on the divergent actors that transform our borders and give meaning to the multiscalar bordering practices.
    Keywords migration ; crimmigration ; border criminology ; Social Sciences ; H ; Social pathology. Social and public welfare. Criminology ; HV1-9960
    Subject code 940
    Language English
    Publishing date 2021-09-01T00:00:00Z
    Publisher Queensland University of Technology
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Crimmigration in Europe.

    van der Woude, Maartje / Barker, Vanessa / van der Leun, Joanne

    European journal of criminology

    2017  Volume 14, Issue 1, Page(s) 3–6

    Language English
    Publishing date 2017-01-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2135314-1
    ISSN 1741-2609 ; 1477-3708
    ISSN (online) 1741-2609
    ISSN 1477-3708
    DOI 10.1177/1477370816639814
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Crimmigration checks in the internal border areas of the EU: Finding the discretion that matters.

    van der Woude, Maartje / van der Leun, Joanne

    European journal of criminology

    2017  Volume 14, Issue 1, Page(s) 27–45

    Abstract: ... on external borders (Van der Woude and Van Berlo, 2015). Internal borders were supposed to disappear under ...

    Abstract Internal borders are a major but understudied site of crimmigration as most scholarship has focused on external borders (Van der Woude and Van Berlo, 2015). Internal borders were supposed to disappear under the principle of free movement within the European Union. But today we see EU member states policing the borders inside Schengen, checking identification, verifying passage, and regulating mobility in so-called 'gray zones'. This article investigates this type of policing within the EU, focusing on the case of the Netherlands. It argues that the policing of internal borders is highly dependent upon discretionary power, a significant factor in the crimmigration process that we do not know enough about. Following Hawkins (1992, 2003), Schneider (1992), and Bushway and Forst (2013) on discretion and discretionary decision-making, we examine the interaction between decisions by law-makers and policy-makers that create discretionary space for law enforcement officials on the ground, and the way in which these street-level bureaucrats perceive the discretionary space attributed to them. By zeroing in on the interaction between these two actors, we aim to find the discretionary decision that matters the most in terms of explaining the crimmigration practices, offering a more holistic and interdisciplinary approach to border control. We discuss the implications of this power and the consequences for the European Project as such.
    Language English
    Publishing date 2017-01-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2135314-1
    ISSN 1741-2609 ; 1477-3708
    ISSN (online) 1741-2609
    ISSN 1477-3708
    DOI 10.1177/1477370816640139
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Framing migration and the process of crimmigration: A systematic analysis of the media representation of unauthorized immigrants in the Netherlands.

    Brouwer, Jelmer / van der Woude, Maartje / van der Leun, Joanne

    European journal of criminology

    2017  Volume 14, Issue 1, Page(s) 100–119

    Abstract: In this article we examine whether the proposal to criminalize illegal stay in the Netherlands was preceded by increased negative media attention for unauthorized immigrants. Using a corpus linguistics approach, we carried out a quantitative discourse ... ...

    Abstract In this article we examine whether the proposal to criminalize illegal stay in the Netherlands was preceded by increased negative media attention for unauthorized immigrants. Using a corpus linguistics approach, we carried out a quantitative discourse analysis of all newspaper articles on unauthorized migrants over a period of 15 years. Our results show that the amount of media coverage actually strongly decreased in the years before the proposal, and this coverage was moreover increasingly less negative. This study thus nuances the somewhat popular belief that unauthorized migrants are increasingly portrayed in negative ways and shows that the framing of migrants as criminals is a more diffuse process in which the media seem to follow rather than fuel politics and policy.
    Language English
    Publishing date 2017-01-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2135314-1
    ISSN 1741-2609 ; 1477-3708
    ISSN (online) 1741-2609
    ISSN 1477-3708
    DOI 10.1177/1477370816640136
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Comprehensive overview of autoantibody isotype and subclass distribution.

    Volkov, Mikhail / Coppola, Mariateresa / Huizinga, Ruth / Eftimov, Filip / Huizinga, Tom W J / van der Kooi, Anneke J / Oosten, Liesbeth E M / Raaphorst, Joost / Rispens, Theo / Sciarrillo, Rocco / Titulaer, Maarten J / Wieske, Luuk / Toes, René E M / Huijbers, Maartje G M / van Schie, Karin A / van der Woude, Diane

    The Journal of allergy and clinical immunology

    2022  Volume 150, Issue 5, Page(s) 999–1010

    Abstract: The presence of autoreactive antibodies is a hallmark of many autoimmune diseases. The effector functions of (auto)antibodies are determined by their constant domain, which defines the antibody isotype and subclass. The most prevalent isotype in serum is ...

    Abstract The presence of autoreactive antibodies is a hallmark of many autoimmune diseases. The effector functions of (auto)antibodies are determined by their constant domain, which defines the antibody isotype and subclass. The most prevalent isotype in serum is IgG, which is often the only isotype used in diagnostic testing. Nevertheless, autoantibody responses can have their own unique isotype/subclass profile. Because comparing autoantibody isotype profiles may yield new insights into disease pathophysiology, here we summarize the isotype/subclass profiles of the most prominent autoantibodies. Despite substantial variation between (and within) autoantibody responses, this unprecedented comparison shows that autoantibodies share distinctive isotype patterns across different diseases. Although most autoantibody responses are dominated by IgG (and mainly IgG1), several specific diseases are characterized by a predominance of IgG4. In other diseases, IgE plays a key role. Importantly, shared features of autoantibody isotype/subclass profiles are seen in clinically unrelated diseases, suggesting potentially common trajectories in response evolution, disease pathogenesis, and treatment response. Isotypes beyond IgG are scarcely investigated in many autoantibody responses, leaving substantial gaps in our understanding of the pathophysiology of autoimmune diseases. Future research should address isotype/subclass profiling in more detail and incorporate autoantibody measurements beyond total IgG in disease models and clinical studies.
    MeSH term(s) Humans ; Autoantibodies ; Immunoglobulin G ; Autoimmune Diseases
    Chemical Substances Autoantibodies ; Immunoglobulin G
    Language English
    Publishing date 2022-09-27
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 121011-7
    ISSN 1097-6825 ; 1085-8725 ; 0091-6749
    ISSN (online) 1097-6825 ; 1085-8725
    ISSN 0091-6749
    DOI 10.1016/j.jaci.2022.05.023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Differences in IgG autoantibody Fab glycosylation across autoimmune diseases.

    Koers, Jana / Sciarrillo, Rocco / Derksen, Ninotska I L / Vletter, Esther M / Fillié-Grijpma, Yvonne E / Raveling-Eelsing, Elisabeth / Graça, Nuno A G / Leijser, Thiemo / Pas, Hendri H / Laura van Nijen-Vos, L / Braham, Maaike V J / Buisman, Anne-Marie / de Jong, Jan / Schriek, Angela I / Tio-Gillen, Anne P / Teng, Y K Onno / Steenhuis, Maurice / Swaneveld, Francis H / de Taeye, Steven W /
    van Gils, Marit J / Verschuuren, Jan J G M / Rutgers, Bram / Heeringa, Peter / Horváth, Barbara / Jacobs, Bart C / de Leeuw, Karina / Franssen, Casper F M / Veyradier, Agnès / Coppo, Paul / Gelderman, Kyra A / Marieke van Ham, S / van Els, Cécile A C M / van der Woude, Diane / Huizinga, Ruth / Huijbers, Maartje G / Kuijpers, Taco W / Toes, Rene E M / Bos, Nicolaas A / Rispens, Theo

    The Journal of allergy and clinical immunology

    2023  Volume 151, Issue 6, Page(s) 1646–1654

    Abstract: Background: Increased prevalence of autoantibody Fab glycosylation has been demonstrated for several autoimmune diseases.: Objectives: To study whether elevated Fab glycosylation is a common feature of autoimmunity, this study investigated Fab ... ...

    Abstract Background: Increased prevalence of autoantibody Fab glycosylation has been demonstrated for several autoimmune diseases.
    Objectives: To study whether elevated Fab glycosylation is a common feature of autoimmunity, this study investigated Fab glycosylation levels on serum IgG and its subclasses for autoantibodies associated with a range of different B cell-mediated autoimmune diseases, including rheumatoid arthritis, myasthenia gravis subtypes, pemphigus vulgaris, antineutrophil cytoplasmic antibody-associated vasculitis, systemic lupus erythematosus, anti-glomerular basement membrane glomerulonephritis, thrombotic thrombocytopenic purpura, and Guillain-Barré syndrome.
    Methods: The level of Fab glycosylated IgG antibodies was assessed by lectin affinity chromatography and autoantigen-specific immunoassays.
    Results: In 6 of 10 autoantibody responses, in 5 of 8 diseases, the investigators found increased levels of Fab glycosylation on IgG autoantibodies that varied from 86% in rheumatoid arthritis to 26% in systemic lupus erythematosus. Elevated autoantibody Fab glycosylation was not restricted to IgG
    Conclusions: These data indicate that in chronic but not acute B cell-mediated autoimmune diseases, disease-specific autoantibodies are enriched for Fab glycans.
    MeSH term(s) Humans ; Autoimmune Diseases ; Autoantibodies ; Myasthenia Gravis ; Arthritis, Rheumatoid ; Immunoglobulin G ; Lupus Erythematosus, Systemic ; Autoantigens
    Chemical Substances Autoantibodies ; Immunoglobulin G ; Autoantigens
    Language English
    Publishing date 2023-01-27
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 121011-7
    ISSN 1097-6825 ; 1085-8725 ; 0091-6749
    ISSN (online) 1097-6825 ; 1085-8725
    ISSN 0091-6749
    DOI 10.1016/j.jaci.2022.10.035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Phase II Feasibility and Biomarker Study of Neoadjuvant Trastuzumab and Pertuzumab With Chemoradiotherapy for Resectable Human Epidermal Growth Factor Receptor 2-Positive Esophageal Adenocarcinoma: TRAP Study.

    Stroes, Charlotte I / Schokker, Sandor / Creemers, Aafke / Molenaar, Remco J / Hulshof, Maarten C C M / van der Woude, Stephanie O / Bennink, Roel J / Mathôt, Ron A A / Krishnadath, Kausilia K / Punt, Cornelis J A / Verhoeven, Rob H A / van Oijen, Martijn G H / Creemers, Geert-Jan / Nieuwenhuijzen, Grard A P / van der Sangen, Maurice J C / Beerepoot, Laurens V / Heisterkamp, Joos / Los, Maartje / Slingerland, Marije /
    Cats, Annemieke / Hospers, Geke A P / Bijlsma, Maarten F / van Berge Henegouwen, Mark I / Meijer, Sybren L / van Laarhoven, Hanneke W M

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology

    2019  Volume 38, Issue 5, Page(s) 462–471

    Abstract: Purpose: Approximately 15% to 43% of esophageal adenocarcinomas (EACs) are human epidermal growth factor receptor 2 (HER2) positive. Because dual-agent HER2 blockade demonstrated a survival benefit in breast cancer, we conducted a phase II feasibility ... ...

    Abstract Purpose: Approximately 15% to 43% of esophageal adenocarcinomas (EACs) are human epidermal growth factor receptor 2 (HER2) positive. Because dual-agent HER2 blockade demonstrated a survival benefit in breast cancer, we conducted a phase II feasibility study of trastuzumab and pertuzumab added to neoadjuvant chemoradiotherapy (nCRT) in patients with EAC.
    Patients and methods: Patients with resectable HER2-positive EAC received standard nCRT with carboplatin and paclitaxel and 41.4 Gy of radiotherapy, with 4 mg/kg of trastuzumab on day 1, 2 mg/kg per week during weeks 2 to 6, and 6 mg/kg per week during weeks 7, 10, and 13 and 840 mg of pertuzumab every 3 weeks. The primary end point was feasibility, defined as ≥ 80% completion of treatment with both trastuzumab and pertuzumab. An exploratory comparison of survival with a propensity score-matched cohort receiving standard nCRT was performed, as were exploratory pharmacokinetic and biomarker analyses.
    Results: Of the 40 enrolled patients (78% men; median age, 63 years), 33 (83%) completed treatment with trastuzumab and pertuzumab. No unexpected safety events were observed. R0 resection was achieved in all patients undergoing surgery, with pathologic complete response in 13 patients (34%). Three-year progression-free and overall survival (OS) were 57% and 71%, respectively (median follow-up, 32.1 months). Compared with the propensity score-matched cohort, a significantly longer OS was observed with HER2 blockade (hazard ratio, 0.58; 95% CI, 0.34 to 0.97). Results of pharmacokinetic analysis and activity on [
    Conclusion: Addition of trastuzumab and pertuzumab to nCRT in patients with HER2-positive EAC is feasible and demonstrates potentially promising activity compared with historical controls. HER2 3+ overexpression and Grb7 positivity are potentially predictive for survival and treatment response, respectively.
    MeSH term(s) Adenocarcinoma/metabolism ; Adenocarcinoma/surgery ; Adenocarcinoma/therapy ; Adult ; Aged ; Antibodies, Monoclonal, Humanized/administration & dosage ; Antibodies, Monoclonal, Humanized/adverse effects ; Antibodies, Monoclonal, Humanized/pharmacokinetics ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Antineoplastic Combined Chemotherapy Protocols/pharmacokinetics ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Biomarkers, Tumor/metabolism ; Carboplatin/administration & dosage ; Carboplatin/adverse effects ; Cardiotoxicity/etiology ; Chemoradiotherapy, Adjuvant ; Esophageal Neoplasms/metabolism ; Esophageal Neoplasms/surgery ; Esophageal Neoplasms/therapy ; Esophagectomy ; Feasibility Studies ; Female ; Humans ; Male ; Medication Adherence ; Middle Aged ; Neoadjuvant Therapy ; Paclitaxel/administration & dosage ; Paclitaxel/adverse effects ; Receptor, ErbB-2/metabolism ; Survival Analysis ; Trastuzumab/administration & dosage ; Trastuzumab/adverse effects ; Trastuzumab/pharmacokinetics
    Chemical Substances Antibodies, Monoclonal, Humanized ; Biomarkers, Tumor ; Carboplatin (BG3F62OND5) ; ERBB2 protein, human (EC 2.7.10.1) ; Receptor, ErbB-2 (EC 2.7.10.1) ; pertuzumab (K16AIQ8CTM) ; Trastuzumab (P188ANX8CK) ; Paclitaxel (P88XT4IS4D)
    Language English
    Publishing date 2019-12-06
    Publishing country United States
    Document type Clinical Trial, Phase II ; Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 604914-x
    ISSN 1527-7755 ; 0732-183X
    ISSN (online) 1527-7755
    ISSN 0732-183X
    DOI 10.1200/JCO.19.01814
    Database MEDical Literature Analysis and Retrieval System OnLINE

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