LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 58

Search options

  1. Article: Contexte, enjeux et perspectives de la nutrition à l’hôpital.

    Lenclud, Christophe / Noël, Anne / de Jonghe, Bernard

    Revue de l'infirmiere

    2021  Volume 70, Issue 274, Page(s) 16–18

    Abstract: Undernutrition is common in hospitals, and it worsens the vital and functional prognosis of patients. The earlier it is treated, the more effective it is. The prevention, detection, treatment and monitoring of undernutrition or the risk of undernutrition ...

    Title translation Context, issues and perspectives of nutrition in hospitals.
    Abstract Undernutrition is common in hospitals, and it worsens the vital and functional prognosis of patients. The earlier it is treated, the more effective it is. The prevention, detection, treatment and monitoring of undernutrition or the risk of undernutrition are a public health priority, which directly involves all carers. Management can be improved by their daily collaboration with a transversal nutrition unit.
    MeSH term(s) Hospitals ; Humans ; Malnutrition/prevention & control ; Nutritional Status
    Language French
    Publishing date 2021-07-17
    Publishing country France
    Document type Journal Article
    ZDB-ID 632538-5
    ISSN 1293-8505 ; 0397-7900
    ISSN 1293-8505 ; 0397-7900
    DOI 10.1016/j.revinf.2021.07.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 2782: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article: Nutrition et soins infirmiers.

    Vergon, Isabelle / Carlier, Lidwina / Demoulinger, Nathalie / Noël, Anne / Lenclud, Christophe / de Jonghe, Bernard

    Revue de l'infirmiere

    2021  Volume 70, Issue 274, Page(s) 25–27

    Abstract: Nutritional nursing care, whether prescribed or on its own role, is a fundamental aspect of the fight against undernutrition in hospital, which is a determinant of vital and functional prognosis. This care includes screening for undernutrition and its ... ...

    Title translation Nutrition and nursing.
    Abstract Nutritional nursing care, whether prescribed or on its own role, is a fundamental aspect of the fight against undernutrition in hospital, which is a determinant of vital and functional prognosis. This care includes screening for undernutrition and its risk factors, assessment of intake and feeding difficulties, enrichment of oral nutrition, enteral and parenteral nutrition. Given the complexity and importance of these tasks, a multi-professional approach involving a transverse nutrition unit is beneficial.
    MeSH term(s) Enteral Nutrition ; Humans ; Malnutrition/diagnosis ; Malnutrition/prevention & control ; Nutritional Status ; Nutritional Support ; Parenteral Nutrition
    Language French
    Publishing date 2021-07-16
    Publishing country France
    Document type Journal Article
    ZDB-ID 632538-5
    ISSN 1293-8505 ; 0397-7900
    ISSN 1293-8505 ; 0397-7900
    DOI 10.1016/j.revinf.2021.07.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 2782: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Deep sedation is not necessarily unjustified sedation.

    De Jonghe, Bernard / Outin, Hervé

    American journal of respiratory and critical care medicine

    2013  Volume 187, Issue 8, Page(s) 892–893

    MeSH term(s) Critical Illness/mortality ; Delirium/epidemiology ; Female ; Humans ; Hypnotics and Sedatives/administration & dosage ; Hypnotics and Sedatives/adverse effects ; Male ; Respiration, Artificial/methods
    Chemical Substances Hypnotics and Sedatives
    Language English
    Publishing date 2013-04-15
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.201210-1817LE
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uh II Zs.80: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Prognostication of neurologic outcome after cardiac arrest: standardization of neurological examination conditions is needed.

    De Jonghe, Bernard / Sharshar, Tarek / Outin, Hervé

    Intensive care medicine

    2013  Volume 40, Issue 2, Page(s) 294

    MeSH term(s) Body Temperature/physiology ; Cardiopulmonary Resuscitation ; Heart Arrest/therapy ; Humans ; Hypothermia, Induced/methods ; Outcome Assessment, Health Care/methods
    Language English
    Publishing date 2013-11-22
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-013-3157-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1089: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article: Permissive hypercapnia: does a high PaCO2 level require high sedative doses?

    De Jonghe, Bernard

    Critical care medicine

    2006  Volume 34, Issue 6, Page(s) 1833–1834

    MeSH term(s) Carbon Dioxide/blood ; Dose-Response Relationship, Drug ; Humans ; Hypercapnia/blood ; Hypercapnia/drug therapy ; Hypercapnia/etiology ; Hypnotics and Sedatives/administration & dosage ; Hypnotics and Sedatives/therapeutic use ; Midazolam/administration & dosage ; Midazolam/therapeutic use ; Partial Pressure ; Pulmonary Gas Exchange/physiology ; Respiration, Artificial/adverse effects
    Chemical Substances Hypnotics and Sedatives ; Carbon Dioxide (142M471B3J) ; Midazolam (R60L0SM5BC)
    Language English
    Publishing date 2006-06
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/01.CCM.0000219376.31203.01
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1261: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article: Critical illness neuromyopathy: from risk factors to prevention.

    De Jonghe, Bernard / Finfer, Simon

    American journal of respiratory and critical care medicine

    2007  Volume 175, Issue 5, Page(s) 424–425

    MeSH term(s) Critical Illness ; Global Health ; Humans ; Incidence ; Neuromuscular Diseases/complications ; Neuromuscular Diseases/epidemiology ; Neuromuscular Diseases/prevention & control ; Respiratory Care Units ; Respiratory Insufficiency/epidemiology ; Respiratory Insufficiency/etiology ; Respiratory Insufficiency/prevention & control ; Respiratory Muscles/physiopathology ; Risk Factors
    Language English
    Publishing date 2007-03-01
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 1073-449X ; 0003-0805
    ISSN (online) 1535-4970
    ISSN 1073-449X ; 0003-0805
    DOI 10.1164/rccm.200612-1762ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uh II Zs.80: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article: The ARCA Registry: A Collaborative Global Platform for Advancing Trial Readiness in Autosomal Recessive Cerebellar Ataxias.

    Traschütz, Andreas / Reich, Selina / Adarmes, Astrid D / Anheim, Mathieu / Ashrafi, Mahmoud Reza / Baets, Jonathan / Basak, A Nazli / Bertini, Enrico / Brais, Bernard / Gagnon, Cynthia / Gburek-Augustat, Janina / Hanagasi, Hasmet A / Heinzmann, Anna / Horvath, Rita / de Jonghe, Peter / Kamm, Christoph / Klivenyi, Peter / Klopstock, Thomas / Minnerop, Martina /
    Münchau, Alexander / Renaud, Mathilde / Roxburgh, Richard H / Santorelli, Filippo M / Schirinzi, Tommaso / Sival, Deborah A / Timmann, Dagmar / Vielhaber, Stefan / Wallner, Michael / van de Warrenburg, Bart P / Zanni, Ginevra / Zuchner, Stephan / Klockgether, Thomas / Schüle, Rebecca / Schöls, Ludger / Synofzik, Matthis

    Frontiers in neurology

    2021  Volume 12, Page(s) 677551

    Abstract: Autosomal recessive cerebellar ataxias (ARCAs) form an ultrarare yet expanding group of neurodegenerative multisystemic diseases affecting the cerebellum and other neurological or non-neurological systems. With the advent of targeted therapies for ARCAs, ...

    Abstract Autosomal recessive cerebellar ataxias (ARCAs) form an ultrarare yet expanding group of neurodegenerative multisystemic diseases affecting the cerebellum and other neurological or non-neurological systems. With the advent of targeted therapies for ARCAs, disease registries have become a precious source of real-world quantitative and qualitative data complementing knowledge from preclinical studies and clinical trials. Here, we review the
    Language English
    Publishing date 2021-06-25
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2021.677551
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Insulin and pentastarch for severe sepsis.

    Lacherade, Jean-Claude / Outin, Hervé / De Jonghe, Bernard

    The New England journal of medicine

    2008  Volume 358, Issue 19, Page(s) 2071–2; author reply 2074–5

    MeSH term(s) Blood Glucose/metabolism ; Critical Illness ; Humans ; Hypoglycemic Agents/administration & dosage ; Insulin/administration & dosage ; Sepsis/drug therapy ; Treatment Failure
    Chemical Substances Blood Glucose ; Hypoglycemic Agents ; Insulin
    Language English
    Publishing date 2008-05-08
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc080223
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.34: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: PFN2 and GAMT as common molecular determinants of axonal Charcot-Marie-Tooth disease.

    Juneja, Manisha / Azmi, Abdelkrim / Baets, Jonathan / Roos, Andreas / Jennings, Matthew J / Saveri, Paola / Pisciotta, Chiara / Bernard-Marissal, Nathalie / Schneider, Bernard L / Verfaillie, Catherine / Chrast, Roman / Seeman, Pavel / Hahn, Angelika F / de Jonghe, Peter / Maudsley, Stuart / Horvath, Rita / Pareyson, Davide / Timmerman, Vincent

    Journal of neurology, neurosurgery, and psychiatry

    2018  Volume 89, Issue 8, Page(s) 870–878

    Abstract: Background: Charcot-Marie-Tooth type 2 (CMT2) neuropathy is characterised by a vast clinical and genetic heterogeneity complicating its diagnosis and therapeutic intervention. Identification of molecular signatures that are common to multiple CMT2 ... ...

    Abstract Background: Charcot-Marie-Tooth type 2 (CMT2) neuropathy is characterised by a vast clinical and genetic heterogeneity complicating its diagnosis and therapeutic intervention. Identification of molecular signatures that are common to multiple CMT2 subtypes can aid in developing therapeutic strategies and measuring disease outcomes.
    Methods: A proteomics-based approach was performed on lymphoblasts from CMT2 patients genetically diagnosed with different gene mutations to identify differentially regulated proteins. The candidate proteins were validated through real-time quantitative PCR and western blotting on lymphoblast samples of patients and controls, motor neurons differentiated from patient-derived induced pluripotent stem cells (iPSCs) and sciatic nerves of CMT2 mouse models.
    Results: Proteomic profiling of patient lymphoblasts resulted in the identification of profilin 2 (PFN2) and guanidinoacetate methyltransferase (GAMT) as commonly downregulated proteins in different genotypes compared with healthy controls. This decrease was also observed at the transcriptional level on screening 43 CMT2 patients and 22 controls, respectively. A progressive decrease in PFN2 expression with age was observed in patients, while in healthy controls its expression increased with age. Reduced PFN2 expression was also observed in motor neurons differentiated from CMT2 patient-derived iPSCs and sciatic nerves of CMT2 mice when compared with controls. However, no change in GAMT levels was observed in motor neurons and CMT2 mouse-derived sciatic nerves.
    Conclusions: We unveil PFN2 and GAMT as molecular determinants of CMT2 with possible indications of the role of PFN2 in the pathogenesis and disease progression. This is the first study describing biomarkers that can boost the development of therapeutic strategies targeting a wider spectrum of CMT2 patients.
    MeSH term(s) Adult ; Aged ; Axons/pathology ; Charcot-Marie-Tooth Disease/genetics ; Charcot-Marie-Tooth Disease/pathology ; Female ; Genotype ; Guanidinoacetate N-Methyltransferase/genetics ; Humans ; Male ; Middle Aged ; Mutation ; Pedigree ; Phenotype ; Profilins/genetics ; Proteomics ; Young Adult
    Chemical Substances PFN2 protein, human ; Profilins ; GAMT protein, human (EC 2.1.1.2) ; Guanidinoacetate N-Methyltransferase (EC 2.1.1.2)
    Language English
    Publishing date 2018-02-15
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 3087-9
    ISSN 1468-330X ; 0022-3050
    ISSN (online) 1468-330X
    ISSN 0022-3050
    DOI 10.1136/jnnp-2017-317562
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ui II Zs.93: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Efficacy and safety of sedation with dexmedetomidine in critical care patients: a meta-analysis of randomized controlled trials.

    Constantin, Jean-Michel / Momon, Aurelien / Mantz, Jean / Payen, Jean-François / De Jonghe, Bernard / Perbet, Sebastien / Cayot, Sophie / Chanques, Gerald / Perreira, Bruno

    Anaesthesia, critical care & pain medicine

    2016  Volume 35, Issue 1, Page(s) 7–15

    Abstract: Introduction: Dexmedetomidine may help physicians target a low level of sedation. Unfortunately, the impact of dexmedetomidine on major endpoints remains unclear in intensive care unit (ICU).: Material and methods: To evaluate the association between ...

    Abstract Introduction: Dexmedetomidine may help physicians target a low level of sedation. Unfortunately, the impact of dexmedetomidine on major endpoints remains unclear in intensive care unit (ICU).
    Material and methods: To evaluate the association between dexmedetomidine use with efficacy and safety outcomes, two reviewers independently identified randomized controlled trials comparing dexmedetomidine with other sedative agents in non-post-cardiac surgery critically ill patients in the PubMed and Cochrane databases. Random effects models were considered if heterogeneity was detected using the DerSimonian and Laird estimation method. Statistical heterogeneity between results was assessed by examining forest plots, confidence intervals (CI) and by using the I(2) statistic. The risk of bias was assessed using the risk of bias tool.
    Results: This meta-analysis included 1994 patients from 16 randomized controlled trials. Comparators were lorazepam, midazolam and propofol. Dexmedetomidine was associated with a reduction in ICU length of stays (WMD=-0.304; 95% CI [-0.477, -0.132]; P=0.001), mechanical ventilation duration (WMD=-0.313, 95% CI [-0.523, -0.104]; P=0.003) and delirium incidence (RR=0.812, 95% CI [0.680, 0.968]; P=0.020). Dexmedetomidine is also associated with an increase in the incidence of bradycardia (RR=1.947, 95% CI [1.387, 2.733]; P=0.001) and hypotension (RR=1.264; 95% CI [1.013, 1.576]; P=0.038).
    Conclusions and relevance: In this first meta-analysis including only randomized controlled trials related to ICU patients, dexmedetomidine was associated with a 48h reduction in ICU length of stay, mechanical ventilation duration and delirium occurrence despite a significant heterogeneity among studies. Dexmedetomidine was also associated with an increase in bradycardia and hypotension.
    MeSH term(s) Critical Care/methods ; Dexmedetomidine/adverse effects ; Dexmedetomidine/therapeutic use ; Humans ; Hypnotics and Sedatives/adverse effects ; Hypnotics and Sedatives/therapeutic use ; Randomized Controlled Trials as Topic
    Chemical Substances Hypnotics and Sedatives ; Dexmedetomidine (67VB76HONO)
    Language English
    Publishing date 2016-02
    Publishing country France
    Document type Journal Article ; Meta-Analysis ; Research Support, Non-U.S. Gov't ; Review
    ISSN 2352-5568
    ISSN (online) 2352-5568
    DOI 10.1016/j.accpm.2015.06.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top