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  1. Article: Functional Dyspepsia, So-called.

    Page, R C M

    Buffalo medical and surgical journal

    2023  Volume 33, Issue 10, Page(s) 602–605

    Language English
    Publishing date 2023-01-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 426472-1
    ISSN 1040-3825
    ISSN 1040-3825
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    AMP -365/384-: Show issues

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  2. Article: Chinoidine and Capsicum in Intermittent Fever.

    Page, R C M

    The Southern medical record

    2022  Volume 12, Issue 11, Page(s) 408–411

    Language English
    Publishing date 2022-08-26
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: 1. Chronic Bronchitis. 2. Endocarditis.

    Page, R C M

    Atlanta medical and surgical journal (1884)

    2022  Volume 11, Issue 11, Page(s) 641–646

    Language English
    Publishing date 2022-07-11
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book ; Online ; E-Book: Toxicologic pathology

    Sahota, Pritam S. / Popp, James A. / Hardisty, Jerry F. / Gopinath, Chirukandath / Bouchard, Page R.

    nonclinical safety assessment

    2019  

    Author's details edited by Pritam S. Sahota, James A. Popp, Jerry F. Hardisty, Chirukandath Gopinath, Page R. Bouchard
    Keywords Drug Evaluation, Preclinical ; Risk Assessment ; Toxicity Tests
    Language English
    Size 1 Online-Ressource (xix, 1224 Seiten), Illustrationen
    Edition Second edition
    Publisher CRC Press, Taylor & Francis Group
    Publishing place Boca Raton
    Publishing country United States
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019972025
    ISBN 978-0-4299-9746-4 ; 9781498745307 ; 0-4299-9746-9 ; 149874530X
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Article ; Online: Prison-based democratic therapeutic communities, medication, and the power to exclude.

    Ross, Callum / Page, Ruairi

    Medicine, science, and the law

    2022  Volume 63, Issue 3, Page(s) 248–252

    Abstract: In 1962, the first custodial Democratic Therapeutic Community (DTC) was established in the English prison estate at HMP Grendon. Today, the Category B male prison estate in England and Wales has three DTCs and three 'TC+' units for prisoners with ... ...

    Abstract In 1962, the first custodial Democratic Therapeutic Community (DTC) was established in the English prison estate at HMP Grendon. Today, the Category B male prison estate in England and Wales has three DTCs and three 'TC+' units for prisoners with learning disabilities. There is one DTC in the female estate at HMP Send. The services fall under the remit of the Offender Personality Disorder Pathway, a jointly commissioned initiative that aims to provide a pathway of psychologically informed services for a highly complex and challenging group of prisoners who are likely to have a severe personality disorder. Several of these units make clear that prisoners prescribed psychotropic medicines are specifically excluded from entry and participation in the available therapy. This analysis paper explores whether an evidence-based rationale exists for this practice and examines the impact on those whose care pathways may comprise hospitals and prisons.
    MeSH term(s) Humans ; Male ; Female ; Prisons ; Therapeutic Community ; Prisoners ; Personality Disorders ; England
    Language English
    Publishing date 2022-10-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 301137-9
    ISSN 2042-1818 ; 0025-8024
    ISSN (online) 2042-1818
    ISSN 0025-8024
    DOI 10.1177/00258024221131451
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 206: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  6. Article ; Online: The Rtf1/Prf1-dependent histone modification axis counteracts multi-drug resistance in fission yeast.

    Chen, Jennifer J / Moy, Calvin / Pagé, Viviane / Monnin, Cian / El-Hajj, Ziad W / Avizonis, Daina Z / Reyes-Lamothe, Rodrigo / Tanny, Jason C

    Life science alliance

    2024  Volume 7, Issue 6

    Abstract: RNA polymerase II transcription elongation directs an intricate pattern of histone modifications. This pattern includes a regulatory cascade initiated by the elongation factor Rtf1, leading to monoubiquitylation of histone H2B, and subsequent methylation ...

    Abstract RNA polymerase II transcription elongation directs an intricate pattern of histone modifications. This pattern includes a regulatory cascade initiated by the elongation factor Rtf1, leading to monoubiquitylation of histone H2B, and subsequent methylation of histone H3 on lysine 4. Previous studies have defined the molecular basis for these regulatory relationships, but it remains unclear how they regulate gene expression. To address this question, we investigated a drug resistance phenotype that characterizes defects in this axis in the model eukaryote
    MeSH term(s) Schizosaccharomyces/genetics ; Schizosaccharomyces/metabolism ; RNA Polymerase II/genetics ; RNA Polymerase II/metabolism ; Histone Code ; Histones/genetics ; Histones/metabolism ; Drug Resistance, Multiple
    Chemical Substances RNA Polymerase II (EC 2.7.7.-) ; Histones
    Language English
    Publishing date 2024-03-21
    Publishing country United States
    Document type Journal Article
    ISSN 2575-1077
    ISSN (online) 2575-1077
    DOI 10.26508/lsa.202302494
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  7. Article ; Online: Access to MRI in Patients With Cardiac Implantable Electronic Devices is Variable and an Issue in Australia.

    Page, Nicholas / Chia, Karin / Brazier, David / Manisty, Charlotte / Kozor, Rebecca

    Heart, lung & circulation

    2024  Volume 33, Issue 3, Page(s) 362–367

    Abstract: Aims: This study aimed to characterise the level of access to magnetic resonance imaging (MRI) in Australian hospitals for patients with MR-conditional and non-MR-conditional cardiac implantable electronic devices (CIED), and to identify any barriers ... ...

    Abstract Aims: This study aimed to characterise the level of access to magnetic resonance imaging (MRI) in Australian hospitals for patients with MR-conditional and non-MR-conditional cardiac implantable electronic devices (CIED), and to identify any barriers impeding this access.
    Methods: All Australian Tertiary Referral Public Hospitals (n=38) were surveyed with a mixed qualitative and quantitative questionnaire. Provision of MRI to patients with MR-conditional and non-MR-conditional CIEDs; patient monitoring strategies during scan and personnel in attendance; barriers impeding MRI access.
    Results: Of the 35 (92%) hospitals that completed the survey, a majority (85.7%) scan MR-conditional CIEDs, while a minority (8.6%) scan non-MR-conditional CIEDs. MR-conditional device scanning is often limited to non-pacing dependent patients, excluding implantable cardioverter-defibrillators. In total, 21% of sites exclude thoracic MR scans for CIED patients. Although most centres scan on 1.5 Tesla (T) machines (59%), 10% scan at 3T and 31% scan at both strengths. Sites vary in patient monitoring strategies and personnel in attendance; 80% require staff with Advanced Cardiac Life Support to be present. Barriers to service expansion include an absence of national guidelines, formal training, and logistical device support.
    Conclusions: Most surveyed Australian hospitals offer MRI for patients with MR-conditional CIEDs, however many still have exclusions for particular patient groups or scan requests. Only three surveyed sites offer MRI for patients with non-MR-conditional CIEDs in Australia. A national effort is needed to address the identified barriers including the development of national guidelines, formal training, and logistical support.
    MeSH term(s) Humans ; Pacemaker, Artificial ; Australia/epidemiology ; Defibrillators, Implantable ; Magnetic Resonance Imaging/methods ; Heart
    Language English
    Publishing date 2024-02-07
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2020980-0
    ISSN 1444-2892 ; 1443-9506
    ISSN (online) 1444-2892
    ISSN 1443-9506
    DOI 10.1016/j.hlc.2023.11.020
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4988: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  8. Article: VEGF-A related SNPs: a cardiovascular context.

    Meza-Alvarado, J C / Page, R A / Mallard, B / Bromhead, C / Palmer, B R

    Frontiers in cardiovascular medicine

    2023  Volume 10, Page(s) 1190513

    Abstract: Cardiovascular diseases (CVDs) are the leading cause of death worldwide. Currently, cardiovascular disease risk algorithms play a role in primary prevention. However, this is complicated by a lack of powerfully predictive biomarkers that could be ... ...

    Abstract Cardiovascular diseases (CVDs) are the leading cause of death worldwide. Currently, cardiovascular disease risk algorithms play a role in primary prevention. However, this is complicated by a lack of powerfully predictive biomarkers that could be observed in individuals before the onset of overt symptoms. A key potential biomarker for heart disease is the vascular endothelial growth factor (VEGF-A), a molecule that plays a pivotal role in blood vessel formation. This molecule has a complex biological role in the cardiovascular system due to the processes it influences, and its production is impacted by various CVD risk factors. Research in different populations has shown single nucleotide polymorphisms (SNPs) may affect circulating VEGF-A plasma levels, with some variants associated with the development of CVDs, as well as CVD risk factors. This minireview aims to give an overview of the VEGF family, and of the SNPs reported to influence VEGF-A levels, cardiovascular disease, and other risk factors used in CVD risk assessments.
    Language English
    Publishing date 2023-05-23
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2023.1190513
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Occupational Adaptation of People Living With Fibromyalgia: A Systematic Review and Thematic Synthesis.

    Dépelteau, Andréa / Lagueux, Émilie / Pagé, Raphaël / Hudon, Catherine

    The American journal of occupational therapy : official publication of the American Occupational Therapy Association

    2021  Volume 75, Issue 4

    Abstract: Importance: Fibromyalgia (FM) is a chronic pain disorder that interferes with daily activities. Because occupational adaptation varies among people, there is a need to determine which factors can influence adaptation to FM in order to better intervene ... ...

    Abstract Importance: Fibromyalgia (FM) is a chronic pain disorder that interferes with daily activities. Because occupational adaptation varies among people, there is a need to determine which factors can influence adaptation to FM in order to better intervene with them.
    Objective: To understand the occupational adaptation process of people living with FM.
    Data sources: A systematic review of the literature was conducted in the AMED, CINAHL, MEDLINE, OTseeker, OTDBASE, and PsycINFO databases. Articles dated before September 2020 were searched using a strategy with the keywords fibromyalgia and occupation. Study Selection and Data Collection: This article follows the Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist. Qualitative articles were included if they documented occupational aspects of participants with FM. Two independent reviewers screened the articles and performed the quality assessment using the Critical Appraisal Skills Program checklist. A thematic synthesis was conducted.
    Findings: Of the 560 articles identified, 347 remained after duplicates were removed. After screening titles and abstracts, 303 articles were rejected, and 44 articles were read in their entirety. Twelve qualitative articles were included in the review. The synthesis highlights that support from relatives is a key to successfully adapting to FM. Identity is crucial to a fulfilled life, and occupational competence is greatly affected by the experience of FM. Occupational adaptation is an issue for some people, but maintaining routines and integrating management strategies would help them to achieve it.
    Conclusions and relevance: This review highlights the importance of considering the components of occupational adaptation while caring for people with FM. What This Article Adds: This systematic review identifies the factors influencing the occupational adaptation of people living with FM and emphasizes the importance of addressing those factors.
    MeSH term(s) Fibromyalgia ; Humans ; Occupations ; Reading
    Language English
    Publishing date 2021-11-15
    Publishing country United States
    Document type Journal Article ; Systematic Review
    ZDB-ID 219403-x
    ISSN 1943-7676 ; 0272-9490 ; 0161-326X
    ISSN (online) 1943-7676
    ISSN 0272-9490 ; 0161-326X
    DOI 10.5014/ajot.2021.047134
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 319: Show issues Location:
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  10. Article ; Online: Health services under pressure: a scoping review and development of a taxonomy of adaptive strategies.

    Page, Bethan / Irving, Dulcie / Amalberti, Rene / Vincent, Charles

    BMJ quality & safety

    2023  

    Abstract: Objective: The objective of this review was to develop a taxonomy of pressures experienced by health services and an accompanying taxonomy of strategies for adapting in response to these pressures. The taxonomies were developed from a review of ... ...

    Abstract Objective: The objective of this review was to develop a taxonomy of pressures experienced by health services and an accompanying taxonomy of strategies for adapting in response to these pressures. The taxonomies were developed from a review of observational studies directly assessing care delivered in a variety of clinical environments.
    Design: In the first phase, a scoping review of the relevant literature was conducted. In the second phase, pressures and strategies were systematically coded from the included papers, and categorised.
    Data sources: Electronic databases (MEDLINE, Embase, CINAHL, PsycInfo and Scopus) and reference lists from recent reviews of the resilient healthcare literature.
    Eligibility criteria: Studies were included from the resilient healthcare literature, which used descriptive methodologies to directly assess a clinical environment. The studies were required to contain strategies for managing under pressure.
    Results: 5402 potential articles were identified with 17 papers meeting the inclusion criteria. The principal source of pressure described in the studies was the demand for care exceeding capacity (ie, the resources available), which in turn led to difficult working conditions and problems with system functioning. Strategies for responding to pressures were categorised into anticipatory and on-the-day adaptations. Anticipatory strategies included strategies for increasing resources, controlling demand and plans for managing the workload (efficiency strategies, forward planning, monitoring and co-ordination strategies and staff support initiatives). On-the-day adaptations were categorised into: flexing the use of existing resources, prioritising demand and adapting ways of working (leadership, teamwork and communication strategies).
    Conclusions: The review has culminated in an empirically based taxonomy of pressures and an accompanying taxonomy of strategies for adapting in response to these pressures. The taxonomies could help clinicians and managers to optimise how they respond to pressures and may be used as the basis for training programmes and future research evaluating the impact of different strategies.
    Language English
    Publishing date 2023-11-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2592909-4
    ISSN 2044-5423 ; 2044-5415
    ISSN (online) 2044-5423
    ISSN 2044-5415
    DOI 10.1136/bmjqs-2023-016686
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3754: Show issues Location:
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