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Article ; Online: A diversidade custodial das cartas do vice-rei 2º marquês do Lavradio e o manuscrito inédito da Biblioteca Brasiliana Guita e José Mindlin

Acervo, Vol 27, Iss

2014 Volume 2

Abstract: ... chave: cultura escrita; correspondência; marquês do Lavradio (2º); Biblioteca Brasiliana Guita e José ... marquis of Lavradio (2nd); Biblioteca Brasiliana Guita e José Mindlin. Resumen En 1768 el segundo marqués ... de Lavradio (2º); Biblioteca Brasiliana Guita e José Mindlin. ...

Abstract	Resumo Em 1768 o 2º marquês do Lavradio chegou à Bahia para governá-la e logo foi transferido para o Rio de Janeiro, nomeado vice-rei, permanecendo no Brasil até 1779. Durante sua administração escreveu centenas de cartas, públicas e particulares. Assim, o objetivo deste texto é analisar a diversidade custodial desta correspondência, em diálogo com a história social da cultura escrita. Palavras-chave: cultura escrita; correspondência; marquês do Lavradio (2º); Biblioteca Brasiliana Guita e José Mindlin. Abstract In 1768 the 2nd Marquis of Lavradio arrived in Bahia to govern it and soon was transferred to Rio de Janeiro, as viceroy, remaining in Brazil until 1779. During his administration he wrote hundreds of public and private letters. This paper aims to analyze the custodial diversity of this correspondence, in light of the social history of written culture. Keywords: written culture; correspondence; marquis of Lavradio (2nd); Biblioteca Brasiliana Guita e José Mindlin. Resumen En 1768 el segundo marqués del Lavradio llegó a Bahía para gobernarla y pronto se trasladó a Río de Janeiro, virrey designado, permaneciendo en Brasil hasta 1779. Durante su administración, escribió cientos de cartas, públicas y privadas. Así, el objetivo de este trabajo es analizar la diversidad custodial de esta correspondencia, en diálogo con la historia social de la cultura escrita. Palabras claves: cultura escrita; correspondencia; marqués de Lavradio (2º); Biblioteca Brasiliana Guita e José Mindlin.
Keywords	Diplomatics. Archives. Seals ; CD1-6471 ; Bibliography. Library science. Information resources ; Z
Language	English
Publishing date	2014-09-01T00:00:00Z
Publisher	Arquivo Nacional
Document type	Article ; Online
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Article ; Online: epidWaves

Cunha, Americo / Batista, Fernando da Conceição / Gianfelice, Paulo Roberto de Lima / Oyarzabal, Ricardo Sovek / Grzybowski, Jose Mario Vicensi / Macau, Elbert E N

Software impacts

2022 Volume 14, Page(s) 100391

Abstract: The COVID-19 pandemic has given rise to a great demand for computational models capable of describing and inferring the evolution of an epidemic outbreak in the short term. In this sense, we ... ...

Abstract	The COVID-19 pandemic has given rise to a great demand for computational models capable of describing and inferring the evolution of an epidemic outbreak in the short term. In this sense, we introduce
Language	English
Publishing date	2022-07-26
Publishing country	Netherlands
Document type	Journal Article
ISSN	2665-9638
ISSN (online)	2665-9638
DOI	10.1016/j.simpa.2022.100391
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Article ; Online: Immunogenicity of an inactivated vaccine for intravaginal application against bovine alphaherpesvirus type 5 (BoHV-5).

Peter, Cristina Mendes / da Silva Barcelos, Lariane / Ferreira, Marcos Roberto Alves / Waller, Stefanie Bressan / Frühauf, Matheus Iuri / Botton, Nadálin Yandra / Conceição, Fabricio Rochedo / de Lima, Marcelo / de Oliveira Hübner, Silvia / Barichello, José Mario / Fischer, Geferson

Molecular immunology

2023 Volume 155, Page(s) 69–78

Abstract: The present study was carried out to evaluate the intravaginal vaccine potential against bovine alphaherpesvirus type 5 (BoHV-5). Sixty three cows were divided into seven groups (n: 9) and inoculated intravaginally (VA) or intramuscularly (IM) with ... ...

Abstract	The present study was carried out to evaluate the intravaginal vaccine potential against bovine alphaherpesvirus type 5 (BoHV-5). Sixty three cows were divided into seven groups (n: 9) and inoculated intravaginally (VA) or intramuscularly (IM) with inactivated BoHV-5, associated with the recombinant B subunit of the heat-labile enterotoxin of E. coli (rLTB), 2-hydroxyethylcellulose (Drug Delivery System A - DDS-A) or Poloxamer 407 (Drug Delivery System B - DDS-B) as follows: G1 (DDS-A + BoHV-5 + rLTB), G2 (DDS-A + BoHV-5), G3 (DDS-B + BoHV-5 + rLTB), G4 (DDS-B + BoHV-5), G5 (BoHV-5 + rLTB), G6 (Negative control) e G7 (Positive control). The local and systemic humoral responses were measured by indirect ELISA (IgA and IgG) and serum neutralization tests, and the cellular response was measured by a quantitative direct ELISA (IL-2 and IFN-Gamma). The results showed the group inoculated by the IM route, G5, demonstrated the highest levels of IgG in the vaginal mucosa among the experimental groups (p < 0.05). In the groups tested with polymers (G1 and G3) in the vaginal mucosa, even higher levels of IgG were seen in comparison to the positive control (G7; p < 0.01). Higher levels of IgA were also noted in relation to the other groups (p < 0.05) on days 30, 60 and 90 post-inoculations. The groups G1 and G3 also provided higher titers of neutralizing antibodies (Log2) in relation to other treatments (p < 0.01) 90 days after inoculation. In the nasal mucosa, there was an increase in the levels of IgA and IgG with the use of vaccines from groups G1 and G3, in relation to the positive control, G7 (p < 0.05) at 60 and 90 days after the first inoculation. Moreover, neutralizing antibodies titers were detected at 60 and 90 days by serum neutralization. The inclusion of the evaluated polymers resulted in a superior response (p < 0.05) of immunoglobulins and IL-2 and IFN-Gamma in relation to the treatment using only rLTB (G5). This data demonstrates the capabilities of a vaccine with an intravaginal application in cattle to stimulate a local and systemic immune response.
MeSH term(s)	Animals ; Female ; Cattle ; Escherichia coli ; Vaccines, Inactivated ; Interleukin-2 ; Antibodies, Neutralizing ; Immunoglobulin G ; Immunoglobulin A ; Polymers ; Antibodies, Viral ; Viral Vaccines
Chemical Substances	Vaccines, Inactivated ; Interleukin-2 ; Antibodies, Neutralizing ; Immunoglobulin G ; Immunoglobulin A ; Polymers ; Antibodies, Viral ; Viral Vaccines
Language	English
Publishing date	2023-01-31
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	424427-8
ISSN	1872-9142 ; 0161-5890
ISSN (online)	1872-9142
ISSN	0161-5890
DOI	10.1016/j.molimm.2023.01.007
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Article ; Online: The Acute Effects of a Swimming Session on the Shoulder Rotators Strength and Balance of Age Group Swimmers.

Batalha, Nuno / Parraca, Jose A / Marinho, Daniel A / Conceição, Ana / Louro, Hugo / Silva, António J / Costa, Mário J

International journal of environmental research and public health

2021 Volume 18, Issue 15

Abstract: The purpose of this study was to analyze the acute effects of a standardized water training session on the shoulder rotators strength and balance in age group swimmers, in order to understand whether a muscle-strengthening workout immediately after the ... ...

Abstract	The purpose of this study was to analyze the acute effects of a standardized water training session on the shoulder rotators strength and balance in age group swimmers, in order to understand whether a muscle-strengthening workout immediately after the water training is appropriate. A repeated measures design was implemented with two measurements performed before and after a standardized swim session. 127 participants were assembled in male (
MeSH term(s)	Adolescent ; Female ; Humans ; Male ; Muscle Strength ; Range of Motion, Articular ; Shoulder ; Shoulder Joint ; Swimming ; Torque
Language	English
Publishing date	2021-07-30
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph18158109
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Article ; Online: Pesquisa clínica no paciente pediátrico.

Conceição, Mário José da

Revista brasileira de anestesiologia

2009 Volume 57, Issue 3, Page(s) 233–236

Title translation	Clinical research on pediatric patients..
Language	Portuguese
Publishing date	2009-02-03
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	604154-1
ISSN	1806-907X ; 0034-7094
ISSN (online)	1806-907X
ISSN	0034-7094
DOI	10.1590/s0034-70942007000300001
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Article: Critical reading of the statistical data in scientific studies.

da Conceição, Mário José

Revista brasileira de anestesiologia

2009 Volume 58, Issue 3, Page(s) 260–266

Abstract: Background and objectives: Statistics are a valuable tool that validates the conclusions of scientific works. The objective of this review was to present some concepts related to statistic calculations that are fundamental for the critical reading and ... ...

Abstract	Background and objectives: Statistics are a valuable tool that validates the conclusions of scientific works. The objective of this review was to present some concepts related to statistic calculations that are fundamental for the critical reading and analysis of medical literature. Contents: In general, authors present the results of their studies as charts, boxes, and tables with quantitative data, along with descriptive statistics (means, standard deviations, medians), and almost always mention the statistic tests used. After reviewing several studies, it was difficult to find the value attributed to the statistical test. Thus, it is up to the reader to evaluate the adequacy of the information, and to search for evidence that contradict possible mistakes that could threaten the validity of their conclusion. Conclusions: Examining the design of the studies one observes that, in many of them, excessive importance is given to statistical calculations as definitive factors, irrefutable evidence of arguable, or equivocal, conclusions.
MeSH term(s)	Data Interpretation, Statistical ; Humans
Language	Portuguese
Publishing date	2009-04-15
Publishing country	Brazil
Document type	Journal Article ; Review
ZDB-ID	604154-1
ISSN	1806-907X ; 0034-7094
ISSN (online)	1806-907X
ISSN	0034-7094
DOI	10.1590/s0034-70942008000300009
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Article ; Online: Transfusão sangüínea em crianças e os métodos para evitá-la: uma reavaliação.

Conceição, Mário José da

Revista brasileira de anestesiologia

2009 Volume 54, Issue 2, Page(s) 276–282

Abstract: Background and objectives: Several approaches and techniques are used in adult patients to decrease or prevent both blood loss and homologous blood transfusion during surgical procedures where massive blood losses are expected. While these blood-sparing ...

Title translation	Blood transfusion in pediatric patients and strategies to decrease it: a reevaluation..
Abstract	Background and objectives: Several approaches and techniques are used in adult patients to decrease or prevent both blood loss and homologous blood transfusion during surgical procedures where massive blood losses are expected. While these blood-sparing strategies are widely used in adults, they are mostly neglected in children. Perhaps in pediatric patients, these blood-sparing techniques may not be as effective as in adults and technical limitations, as the small size of patients could limit its advantages. In the following review, blood-sparing techniques established for adults are described and their applicability in pediatric patients discussed. Contents: Blood-sparing strategies developed for adult patients aiming at decreasing or even preventing homologous blood transfusion when massive blood losses are expected, are presented through a bibliographic review. Since all known methods were developed for adult patients, an action line was drawn for the reevaluation of these methods, techniques and drugs to be used in pediatric patients. Conclusions: It has become once more clear that solutions for adult patients may not be as effective for pediatric patients. Intraoperative blood-sparing techniques and consequent decrease in the need for homologous blood are effective for adult patients but are by far more invasive, complicated, and some of them ineffective in pediatric patients, especially those under two years of age.
Language	Portuguese
Publishing date	2009-04-01
Publishing country	Brazil
Document type	English Abstract ; Journal Article
ZDB-ID	604154-1
ISSN	1806-907X ; 0034-7094
ISSN (online)	1806-907X
ISSN	0034-7094
DOI	10.1590/s0034-70942004000200015
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Article ; Online: The starting dates of COVID-19 multiple waves.

de Lima Gianfelice, Paulo Roberto / Sovek Oyarzabal, Ricardo / Cunha, Americo / Vicensi Grzybowski, Jose Mario / da Conceição Batista, Fernando / E N Macau, Elbert

Chaos (Woodbury, N.Y.)

2022 Volume 32, Issue 3, Page(s) 31101

Abstract: The severe acute respiratory syndrome of coronavirus 2 spread globally very quickly, causing great concern at the international level due to the severity of the associated respiratory disease, the so-called COVID-19. Considering Rio de Janeiro city ( ... ...

Abstract	The severe acute respiratory syndrome of coronavirus 2 spread globally very quickly, causing great concern at the international level due to the severity of the associated respiratory disease, the so-called COVID-19. Considering Rio de Janeiro city (Brazil) as an example, the first diagnosis of this disease occurred in March 2020, but the exact moment when the local spread of the virus started is uncertain as the Brazilian epidemiological surveillance system was not widely prepared to detect suspected cases of COVID-19 at that time. Improvements in this surveillance system occurred over the pandemic, but due to the complex nature of the disease transmission process, specifying the exact moment of emergence of new community contagion outbreaks is a complicated task. This work aims to propose a general methodology to determine possible start dates for the multiple community outbreaks of COVID-19, using for this purpose a parametric statistical approach that combines surveillance data, nonlinear regression, and information criteria to obtain a statistical model capable of describing the multiple waves of contagion observed. The dynamics of COVID-19 in the city of Rio de Janeiro is taken as a case study, and the results suggest that the original strain of the virus was already circulating in Rio de Janeiro city as early as late February 2020, probably being massively disseminated in the population during the carnival festivities.
MeSH term(s)	Brazil/epidemiology ; COVID-19/epidemiology ; Disease Outbreaks ; Humans
Language	English
Publishing date	2022-04-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	1472677-4
ISSN	1089-7682 ; 1054-1500
ISSN (online)	1089-7682
ISSN	1054-1500
DOI	10.1063/5.0079904
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Article ; Online: T cell-specific P2RX7 favors lung parenchymal CD4

Santiago-Carvalho, Igor / Almeida-Santos, Gislane / Macedo, Bruna Gois / Barbosa-Bomfim, Caio Cesar / Almeida, Fabricio Moreira / Pinheiro Cione, Marcos Vinícios / Vardam-Kaur, Trupti / Masuda, Mia / Van Dijk, Sarah / Melo, Bruno Marcel / Silva do Nascimento, Rogério / da Conceição Souza, Rebeka / Peixoto-Rangel, Alba Lucínia / Coutinho-Silva, Robson / Hirata, Mario Hiroyuki / Alves-Filho, José Carlos / Álvarez, José Maria / Lassounskaia, Elena / Borges da Silva, Henrique /

D'Império-Lima, Maria Regina

Cell reports

2023 Volume 42, Issue 11, Page(s) 113448

Abstract: ... ...

Abstract	CD4
MeSH term(s)	Animals ; Humans ; Mice ; CD4-Positive T-Lymphocytes ; Influenza, Human/metabolism ; Lung/pathology ; Receptors, Chemokine/metabolism ; Tuberculosis/pathology
Chemical Substances	Receptors, Chemokine ; P2rx7 protein, mouse
Language	English
Publishing date	2023-11-15
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	2649101-1
ISSN	2211-1247 ; 2211-1247
ISSN (online)	2211-1247
ISSN	2211-1247
DOI	10.1016/j.celrep.2023.113448
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Article: Critical reading of the statistical data in scientific studies.

Conceição, Mário José da

Revista brasileira de cirurgia cardiovascular : orgao oficial da Sociedade Brasileira de Cirurgia Cardiovascular

2008 Volume 23, Issue 3, Page(s) 396–399

Abstract: Objectives: Statistics are a valuable tool that validates the conclusions of scientific works. The objective of this review was to present some concepts related to statistic calculations that are fundamental for the critical reading and analysis of ... ...

Abstract	Objectives: Statistics are a valuable tool that validates the conclusions of scientific works. The objective of this review was to present some concepts related to statistic calculations that are fundamental for the critical reading and analysis of medical literature. Contents: In general, authors present the results of their studies as charts, boxes, and tables with quantitative data, along with descriptive statistics (means, standard deviations, medians), and almost always mention the statistic tests used. After reviewing several studies, it was difficult to find the value attributed to the statistical test. Thus, it is up to the reader to evaluate the adequacy of the information, and to search for evidence that contradict possible mistakes that could threaten the validity of their conclusion. Conclusions: Examining the design of the studies one observes that, in many of them, excessive importance is given to statistical calculations as definitive factors, irrefutable evidence of arguable, or equivocal, conclusions.
MeSH term(s)	Biomedical Research ; Data Interpretation, Statistical ; Humans ; Reading ; Research Design/standards
Language	Portuguese
Publishing date	2008-12-10
Publishing country	Brazil
Document type	Journal Article
DOI	10.1590/s0102-76382008000300018
Database	MEDical Literature Analysis and Retrieval System OnLINE

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