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Book: Lao dong wei sheng yu zhi ye bing xue

Liu, Shijie

(Zhong guo yi xue bai ke quan shu)

1988

Title translation	Labor hygiene and occupational diseases.
Author's details	zhu bian Liu Shijie
Series title	Zhong guo yi xue bai ke quan shu
MeSH term(s)	Occupational Diseases ; Occupational Medicine
Language	Chinese
Size	4, 232 p.
Edition	Di 1 ban.
Publisher	Shanghai ke hsëh ji shu chu ban she
Publishing place	Shanghai
Document type	Book
ISBN	9787532309320 ; 7532309320
Database	Catalogue of the US National Library of Medicine (NLM)

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Article ; Online: Multiscale structure changes and mechanism of polyphenol-amylose complexes modulated by polyphenolic structures.

Wei, Xianling / Xie, Huan / Hu, Ziqing / Zeng, Xiaofang / Dong, Hao / Liu, Xiaoyan / Bai, Weidong

International journal of biological macromolecules

2024 Volume 262, Issue Pt 2, Page(s) 130086

Abstract: This study was designed to investigate the effect of polyphenolic structure on the interaction strength and process between polyphenols (gallic acid (GA), epigallocatechin gallate (EGCG) and tannic acid (TA)) and amylose (AM). The results of Fourier ... ...

Abstract	This study was designed to investigate the effect of polyphenolic structure on the interaction strength and process between polyphenols (gallic acid (GA), epigallocatechin gallate (EGCG) and tannic acid (TA)) and amylose (AM). The results of Fourier transform infrared spectroscopy, isothermal titration calorimetry, X-ray photoelectron spectroscopy and molecular dynamic simulation (MD) suggested that the interactions between the three polyphenols and AM were noncovalent, spontaneous, low-energy and driven by enthalpy, which would be enhanced with increasing amounts of pyrogallol groups in the polyphenols. The results of turbidity, particle size and appearance of the complex solution showed that the interaction process between polyphenols and AM could be divided into three steps and would be advanced by increasing the number of pyrogallol groups in the polyphenols. At the same time, MD was intuitively employed to exhibit the interaction process between amylose and polyphenols, and it revealed that the interaction induced the aggregation of amylose and that the agglomeration degree of amylose increased with increasing number of pyrogallol groups at polyphenols. Last, the SEM and TGA results showed that TA/AM complexes had the tightest structure and the highest thermal stability (TA/AM˃EGCG/AM˃GA/AM), which could be attributed to TA having five pyrogallol groups.
MeSH term(s)	Amylose ; Pyrogallol/chemistry ; Polyphenols/chemistry ; Gallic Acid/chemistry
Chemical Substances	Tannic Acid ; Amylose (9005-82-7) ; Pyrogallol (01Y4A2QXY0) ; Polyphenols ; Gallic Acid (632XD903SP)
Language	English
Publishing date	2024-02-14
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2024.130086
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Article ; Online: An IoT-based low-cost architecture for smart libraries using SDN.

Xu, Hui / Liu, Wei-Dong / Li, Lu / Zhou, Qi

Scientific reports

2024 Volume 14, Issue 1, Page(s) 7022

Abstract: In the evolving landscape of smart libraries, this research pioneers an IoT-based low-cost architecture utilizing Software-Defined Networking (SDN). The increasing demand for more efficient and economical solutions in library management, particularly in ... ...

Abstract	In the evolving landscape of smart libraries, this research pioneers an IoT-based low-cost architecture utilizing Software-Defined Networking (SDN). The increasing demand for more efficient and economical solutions in library management, particularly in the realm of RFID-based processes such as authentication, property circulation, and book loans, underscores the significance of this study. Leveraging the collaborative potential of IoT and SDN technologies, our proposed system introduces a fresh perspective to tackle these challenges and advance intelligent library management. In response to the evolving landscape of smart libraries, our research presents an Internet of Things (IoT)-based low-cost architecture utilizing SDN. The exploration of this architectural paradigm arises from a recognized gap in the existing literature, pointing towards the necessity for more efficient and cost-effective solutions in managing library processes. Our proposed algorithm integrates IoT and SDN technologies to intelligently oversee various library activities, specifically targeting RFID-based processes such as authentication, property circulation management, and book loan management. The system's architecture, encompasses components like the data center, SDN controllers, RFID tags, tag readers, and other network sensors. By leveraging the synergy between RFID and SDN, our innovative approach reduces the need for constant operator supervision in libraries. The scalability and software-oriented nature of the architecture cater to extensive library environments. Our study includes a two-phase investigation, combining practical implementation in a small-scale library with a simulation environment using MATLAB 2021. This research not only fills a crucial gap in current knowledge but also lays the foundation for future advancements in the integration of IoT and SDN technologies for intelligent library management.
Language	English
Publishing date	2024-03-25
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-57484-2
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Article ; Online: YTHDC1 promotes the malignant progression of gastric cancer by promoting ROD1 translocation to the nucleus.

Dong, Danhong / Wei, Jiangpeng / Wang, Weidong / Zhou, Haikun / Hong, Liu / Ji, Gang / Yang, Xisheng

Cell biology and toxicology

2024 Volume 40, Issue 1, Page(s) 19

Abstract: RNA-binding proteins (RBPs) make vital impacts on tumor progression and are important potential targets for tumor treatment. Previous studies have shown that RBP regulator of differentiation 1 (ROD1), enriched in the nucleus, is abnormally expressed and ... ...

Abstract	RNA-binding proteins (RBPs) make vital impacts on tumor progression and are important potential targets for tumor treatment. Previous studies have shown that RBP regulator of differentiation 1 (ROD1), enriched in the nucleus, is abnormally expressed and functions as a splicing factor in tumors; however, the mechanism underlying its involvement in gastric cancer (GC) is unknown. In this study, ROD1 is found to stimulate GC cell proliferation and metastasis and is related to poor patient prognosis. In vitro experiments showed that ROD1 influences GC proliferation and metastasis through modulating the imbalance of the level of the oncogenic gene OIP5 and the tumor suppressor gene GPD1L. Further studies showed that the N6-methyladenosine (m6A) "reader" protein YTHDC1 can interact with ROD1 and regulate the balance of the expression of the downstream molecules OIP5/GPD1L by promoting the nuclear enrichment of ROD1. Therefore, YTHDC1 stimulates GC development and progression through modulating nuclear enrichment of the splicing factor ROD1.
MeSH term(s)	Humans ; Cell Differentiation ; Nerve Tissue Proteins ; RNA Splicing Factors ; Stomach Neoplasms
Chemical Substances	Nerve Tissue Proteins ; RNA Splicing Factors ; YTHDC1 protein, human ; PTBP3 protein, human
Language	English
Publishing date	2024-04-04
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	48824-0
ISSN	1573-6822 ; 0742-2091
ISSN (online)	1573-6822
ISSN	0742-2091
DOI	10.1007/s10565-024-09859-4
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Article: [Building of a Clinical Prediction Model for Hemodynamic Depression after Carotid Artery Stenting].

Fan, Wei-Dong / Liu, Kun / Qiao, Tong

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae

2023 Volume 45, Issue 1, Page(s) 22–27

Abstract: Objective To analyze the risk factors and build a clinical prediction model for hemodynamic depression (HD) after carotid artery stenting (CAS). Methods A total of 116 patients who received CAS in the Department of Vascular Surgery,Drum Tower Clinical ... ...

Abstract	Objective To analyze the risk factors and build a clinical prediction model for hemodynamic depression (HD) after carotid artery stenting (CAS). Methods A total of 116 patients who received CAS in the Department of Vascular Surgery,Drum Tower Clinical College of Nanjing Medical University and the Department of Vascular Surgery,the Affiliated Suqian First People's Hospital of Nanjing Medical University from January 1,2016 to January 1,2022 were included in this study.The patients were assigned into a HD group and a non-HD group.The clinical baseline data and vascular disease characteristics of each group were collected,and multivariate Logistic regression was employed to identify the independent predictors of HD after CAS and build a clinical prediction model.The receiver operating characteristic (ROC) curve was drawn,and the area under the ROC curve (AUC) was calculated to evaluate the predictive performance of the model. Results The HD group had lower proportions of diabetes (
MeSH term(s)	Humans ; Carotid Stenosis ; Depression ; Models, Statistical ; Prognosis ; Stents ; Hemodynamics ; Plaque, Amyloid
Language	Chinese
Publishing date	2023-02-16
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	604853-5
ISSN	1000-503X
ISSN	1000-503X
DOI	10.3881/j.issn.1000-503X.15059
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Article ; Online: Epileptic Seizure Detection with an End-to-End Temporal Convolutional Network and Bidirectional Long Short-Term Memory Model.

Dong, Xingchen / Wen, Yiming / Ji, Dezan / Yuan, Shasha / Liu, Zhen / Shang, Wei / Zhou, Weidong

International journal of neural systems

2024 Volume 34, Issue 3, Page(s) 2450012

Abstract: Automatic seizure detection plays a key role in assisting clinicians for rapid diagnosis and treatment of epilepsy. In view of the parallelism of temporal convolutional network (TCN) and the capability of bidirectional long short-term memory (BiLSTM) in ... ...

Abstract	Automatic seizure detection plays a key role in assisting clinicians for rapid diagnosis and treatment of epilepsy. In view of the parallelism of temporal convolutional network (TCN) and the capability of bidirectional long short-term memory (BiLSTM) in mining the long-range dependency of multi-channel time-series, we propose an automatic seizure detection method with a novel end-to-end TCN-BiLSTM model in this work. First, raw EEG is filtered with a 0.5-45 Hz band-pass filter, and the filtered data are input into the proposed TCN-BiLSTM network for feature extraction and classification. Post-processing process including moving average filtering, thresholding and collar technique is then employed to further improve the detection performance. The method was evaluated on two EEG database. On the CHB-MIT scalp EEG database, our method achieved a segment-based sensitivity of 94.31%, specificity of 97.13%, and accuracy of 97.09%. Meanwhile, an event-based sensitivity of 96.48% and an average false detection rate (FDR) of 0.38/h were obtained. On the SH-SDU database we collected, the segment-based sensitivity of 94.99%, specificity of 93.25%, and accuracy of 93.27% were achieved. In addition, an event-based sensitivity of 99.35% and a false detection rate of 0.54/h were yielded. The total detection time consumed for 1[Formula: see text]h EEG data was 5.65[Formula: see text]s. These results demonstrate the superiority and promising potential of the proposed method in real-time monitoring of epileptic seizures.
MeSH term(s)	Humans ; Memory, Short-Term ; Seizures/diagnosis ; Epilepsy/diagnosis ; Electroencephalography/methods ; Databases, Factual ; Algorithms ; Signal Processing, Computer-Assisted
Language	English
Publishing date	2024-01-17
Publishing country	Singapore
Document type	Journal Article
ISSN	1793-6462
ISSN (online)	1793-6462
DOI	10.1142/S0129065724500126
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Article ; Online: Roles of Nuclear Receptors in Esophageal Cancer.

Deng, Lihao / Liu, Jiaxuan / Chen, Wei-Dong / Wang, Yan-Dong

Current pharmaceutical biotechnology

2023 Volume 24, Issue 12, Page(s) 1489–1503

Abstract: Background: Esophageal cancer (EC), including esophageal squamous cell carcinoma (ESCC) and esophageal adenocarcinoma (EAC), is a highly prevalent malignancy that occurs predominantly in the Asian region and is related to ethnicity, genetics, diet, and ... ...

Abstract	Background: Esophageal cancer (EC), including esophageal squamous cell carcinoma (ESCC) and esophageal adenocarcinoma (EAC), is a highly prevalent malignancy that occurs predominantly in the Asian region and is related to ethnicity, genetics, diet, and lifestyle. The nuclear receptor (NR) superfamily consists of 48 members of the human body. It is a collection of a large class of transcription factors, including Peroxisome proliferator-activated receptors (PPARs), Farnesol X receptor (FXR), Vitamin D receptor (VDR), Retinoic acid receptor (RAR), Pregnane X receptor (PXR), Androgen receptor (AR) and so on. Several NRs have been detected as oncogenes or tumor suppressors in EC progression. Objectives: NRs are associated with the progression of many cancers, including EC. Some NRs, such as PPARs and FXR, play an important role in EC. Studying the molecular mechanism of NRs in EC is helpful for further understanding the development of EC. Preclinical research and development of small molecule compound drugs targeting NRs have provided new ideas for the potential targeted therapy of EC. Methods: This review summarizes the studies on NRs in EC in recent years, mainly including Results: NRs influence EC progress in a variety of ways. They mainly affect the proliferation, migration and drug resistance of EC cells by affecting key cancer cell signaling pathways. Activation or inhibition of NRs inhibits or promotes EC progression, depending on EC types and tumor stages. Preclinical studies mainly focus on the development of small molecule drugs for targeting NRs (such as PPARγ agonists, PPARδ inhibitors, and FXR agonists), and agonists or inhibitors of NRs will become a potential therapeutic regimen for EC. Conclusion: The studies on the roles of NRs in EC have provided a theoretical basis for us to further understand the pathogenesis of EC and develop potential therapeutic drugs targeting NRs for the treatment of different diseases.
MeSH term(s)	Animals ; Humans ; Esophageal Neoplasms/drug therapy ; Peroxisome Proliferator-Activated Receptors ; Esophageal Squamous Cell Carcinoma/drug therapy ; Transcription Factors ; Adenocarcinoma
Chemical Substances	Peroxisome Proliferator-Activated Receptors ; Transcription Factors
Language	English
Publishing date	2023-02-06
Publishing country	Netherlands
Document type	Review ; Journal Article
ZDB-ID	2132197-8
ISSN	1873-4316 ; 1389-2010
ISSN (online)	1873-4316
ISSN	1389-2010
DOI	10.2174/1389201024666230202155426
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Article: [Optimization of ethanol precipitation process of Nauclea officinalis extract based on concept of quality by design(QbD)].

Pei, Xiao-Ting / Liu, Ke / Peng, Lei / Yin, Deng-Ke / Zeng, Ji-Kai / Chen, Wei-Dong

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

2024 Volume 48, Issue 24, Page(s) 6653–6662

Abstract: The ethanol precipitation process of Nauclea officinalis extract was optimized based on the concept of quality by design(QbD). Single factor tests were carried out to determine the levels of test factors. The ethanol volume fraction, pre-ethanol ... ...

Abstract	The ethanol precipitation process of Nauclea officinalis extract was optimized based on the concept of quality by design(QbD). Single factor tests were carried out to determine the levels of test factors. The ethanol volume fraction, pre-ethanol precipitation drug concentration, and ethanol precipitation time were taken as critical process parameters(CPPs). With the comprehensive scores of strictosamide transfer rate and solid removal rate as the critical quality attributes(CQAs), Box-Behnken design was employed to establish the mathematical models and space design between CPPs and CQAs, and the obtained optimal operating space was validated. The optimal operating space included ethanol volume fraction of 65%-70%, pre-ethanol precipitation drug concentration of 22-27 mg·mL~(-1), and ethanol precipitation time of 12 h. Based on the concept of QbD, this study adopted the design space to optimize the ethanol precipitation process of N. officinalis extract, which provided a reliable theoretical basis for the quality control in the production process of N. officinalis preparations. Moroever, this study provided a reference value for guiding the research and industrial production of traditional Chinese medicines.
MeSH term(s)	Drugs, Chinese Herbal ; Ethanol ; Medicine, Chinese Traditional ; Quality Control ; Models, Theoretical
Chemical Substances	Drugs, Chinese Herbal ; Ethanol (3K9958V90M)
Language	Chinese
Publishing date	2024-01-09
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	1004649-5
ISSN	1001-5302 ; 0254-0029
ISSN	1001-5302 ; 0254-0029
DOI	10.19540/j.cnki.cjcmm.20231016.301
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Article ; Online: Study on the microstructure characteristics, compression, and thermal insulation properties of duck down

Yu, Wei-dong / Wang, Lifang / Liu, Hongling / Du, Zhaoqun / Yu, Weidong

Textile Research Journal. 2023 May, v. 93, no. 9-10 p.2382-2393

2023

Abstract: The compression and insulation properties of down are crucial and need to be further explored. This article describes the average number and length of barbs increasing from 67 to 100 and from 11.90 to 26.00 mm with a rise of single down mass, ... ...

Abstract	The compression and insulation properties of down are crucial and need to be further explored. This article describes the average number and length of barbs increasing from 67 to 100 and from 11.90 to 26.00 mm with a rise of single down mass, respectively. The mass of a single down is lognormal, and the average value and maximum probability value of individual down mass are 1.46 and 0.62 mg, respectively. There is no significant difference in α helix or β sheet contents through peak deconvolution of the Fourier transform infrared spectroscopy of the barbs and barbules. The compression recovery rates of single down are 58.29% and 58.94% in the x–x and y–y directions, respectively, due to the almost same structure in both directions. Further, the compression recovery rates of down with filling masses of 0.5, 1.0, and 1.5 g decreased by 6.79%, 5.00%, and 7.31% after five consecutive compression cycles, respectively. The thermal conductivity of the down assembly first decreases to 0.024 W · m⁻¹ · °C⁻¹ and then increased with the compressive deformation, because the relative density and contact points of down fibers are changing. The study into the morphology structure, compression, and thermal properties of down will inspire the design and development of future synthetic insulation materials.
Keywords	Fourier transform infrared spectroscopy ; deformation ; down (feathers) ; fabrics ; insulating materials ; microstructure ; probability ; research ; thermal conductivity ; Duck down ; microstructure structure ; compression performance
Language	English
Dates of publication	2023-05
Size	p. 2382-2393.
Publishing place	SAGE Publications
Document type	Article ; Online
ZDB-ID	2209596-2
ISSN	1746-7748 ; 0040-5175
ISSN (online)	1746-7748
ISSN	0040-5175
DOI	10.1177/00405175221137755
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Research advances in neuroimaging and genetic characteristics of the non-fluent/agrammatic variant of primary progressive aphasia.

Bai, Yi-Jing / Liu, Xiao-Wei / Le, Wei-Dong

Chinese medical journal

2021 Volume 134, Issue 6, Page(s) 665–667

MeSH term(s)	Aphasia, Primary Progressive/diagnostic imaging ; Aphasia, Primary Progressive/genetics ; Humans ; Neuroimaging ; Neuropsychological Tests
Language	English
Publishing date	2021-02-22
Publishing country	China
Document type	Journal Article
ZDB-ID	127089-8
ISSN	2542-5641 ; 0366-6999 ; 1002-0187
ISSN (online)	2542-5641
ISSN	0366-6999 ; 1002-0187
DOI	10.1097/CM9.0000000000001424
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