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Article: The immediate impact of mandatory helmet law on maxillo-facial trauma: A comparative study in a major trauma center, Uttar Pradesh.

Pandey, Arun / Chaturvedi, Thakur P / Sharma, Naresh K / Singh, Akhilesh K / Kumar, Janani A / Mishra, Nitesh

National journal of maxillofacial surgery

2024 Volume 15, Issue 1, Page(s) 116–120

Abstract: Aim: To analyze the effect of the mandatory helmet rule in helmet usage among motorcycle riders and on facial trauma and to determine the significance of difference in the possibility of facial trauma between the helmeted and non-helmeted motorcycle ... ...

Abstract	Aim: To analyze the effect of the mandatory helmet rule in helmet usage among motorcycle riders and on facial trauma and to determine the significance of difference in the possibility of facial trauma between the helmeted and non-helmeted motorcycle riders. Setting and design: A retrospective comparative study conducted in a major trauma center at Uttar Pradesh. Material and method: Data for the present study was obtained from records of the Emergency Department of Trauma Center, for a period of two months before and after the implementation of The Motor Vehicles Act in UP. The study included patients with a history of non-fatal motorcycle accidents who sustained facial injuries regardless of the presence of injuries to other areas of the body during the study period. Information regarding helmet usage during the accident was also recorded. The results were compared between the pre-law period and post-law period. Statistical analysis used: Sample t-test was applied to find the level of significance. Results: Out of 219 injured patients, 152 (69.40%) subjects were not wearing helmets, whereas only 67 (30.59%) subjects were wearing helmets. It was observed that around 68.18% of people stated wearing helmets after law implementation with a statistical significance (P value < 0.05). Conclusion: Our study shows that the mandatory helmet rule with elevated penalty rates has significantly increased the usage of helmet among the motorcycle riders, and it also proves that the possibility of facial trauma is significantly higher in non-helmeted riders when compared to helmeted riders.
Language	English
Publishing date	2024-03-19
Publishing country	India
Document type	Journal Article
ZDB-ID	2653583-X
ISSN	2229-3418 ; 0975-5950
ISSN (online)	2229-3418
ISSN	0975-5950
DOI	10.4103/njms.njms_313_21
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Autoreconstruction of the tongue in case of extensive verrucous carcinoma.

Singh, Akhilesh Kumar / Mishra, Nitesh / Pandey, Arun / Kumar, Janani Anand

National journal of maxillofacial surgery

2022 Volume 13, Issue 2, Page(s) 307–310

Abstract: Tongue reconstruction can be simple to complex depending on the size of the defect. Reconstruction of medium-to-large size defect is technically demanding to achieve better esthetic and functional outcome. There are various options in the reconstruction ... ...

Abstract	Tongue reconstruction can be simple to complex depending on the size of the defect. Reconstruction of medium-to-large size defect is technically demanding to achieve better esthetic and functional outcome. There are various options in the reconstruction of tongue defect when it comes to the type of flap. Any type of flap has its own advantages and disadvantages. Local flaps seem to be the best option, as it avoids secondary donor site morbidity and has similar tissue characteristics as native tissue, therefore provides better esthetic and functional results. This case report illustrates a case of tongue reconstruction that was performed with the help of tongue base island flap after wide local excision of verrucous carcinoma, which provided us with excellent results.
Language	English
Publishing date	2022-07-15
Publishing country	India
Document type	Case Reports
ZDB-ID	2653583-X
ISSN	2229-3418 ; 0975-5950
ISSN (online)	2229-3418
ISSN	0975-5950
DOI	10.4103/njms.NJMS_244_20
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Article ; Online: Anatomical and Histological Characteristics of Prematurely Erupted Teeth in Newborns.

Lokade, Amolkumar / Rahul, Morankar / Mishra, Deepika / Jot, Kiran / Shrivastava, Nikhil / Tewari, Nitesh / Bansal, Kalpana / Mathur, Vijay P

Journal of dentistry for children (Chicago, Ill.)

2023 Volume 90, Issue 3, Page(s) 147–151

Abstract: Purpose: ...

Abstract	Purpose:
MeSH term(s)	Infant, Newborn ; Humans ; Dentin ; Tooth Cervix ; Dental Enamel ; Dental Cementum ; Tooth Eruption
Language	English
Publishing date	2023-12-22
Publishing country	United States
Document type	Journal Article
ZDB-ID	390120-8
ISSN	1935-5068 ; 1551-8949 ; 0022-0353
ISSN (online)	1935-5068
ISSN	1551-8949 ; 0022-0353
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Article: Mediative fuzzy logic mathematical model: A contradictory management prediction in COVID-19 pandemic.

Sharma, M K / Dhiman, Nitesh / Vandana / Mishra, Vishnu Narayan

Applied soft computing

2021 Volume 105, Page(s) 107285

Abstract: This paper presents a model based on mediative fuzzy logic in this COVID-19 pandemic. COVID-19 (novel coronavirus respiratory disease) has become a pandemic now and the whole world has been affected by this disease. Different methodologies and many ... ...

Abstract	This paper presents a model based on mediative fuzzy logic in this COVID-19 pandemic. COVID-19 (novel coronavirus respiratory disease) has become a pandemic now and the whole world has been affected by this disease. Different methodologies and many prediction techniques based on various models have been developed so far. In the present article, we have developed a mediative fuzzy correlation technique based on the parameters for COVID-19 patients from different parts of India. The proposed mediative fuzzy correlation technique provides the relation between the increments of COVID-19 positive patients in terms of the passage of increment with respect to time. The peaks of infected cases in connection with the other condition are estimated from the available data. The mediative fuzzy logic mathematical model can be utilized to find a good fit or a contradictory model for any pandemic model. The proposed approach to the prediction in COVID-19 based on mediative fuzzy logic has produced promising results for the continuous contradictory prediction in India.
Language	English
Publishing date	2021-03-09
Publishing country	United States
Document type	Journal Article
ISSN	1568-4946
ISSN	1568-4946
DOI	10.1016/j.asoc.2021.107285
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Article: Post-symptomatic detection of COVID-2019 grade based mediative fuzzy projection.

Sharma, Mukesh Kumar / Dhiman, Nitesh / Mishra, Vishnu Narayan / Mishra, Lakshmi Narayan / Dhaka, Arvind / Koundal, Deepika

Computers & electrical engineering : an international journal

2022 Volume 101, Page(s) 108028

Abstract: The concept of fuzzy set, intuitionistic set, and mediative fuzzy set as a generalization of a crisp set have been introduced in many real-life applications. The concept of crisp relation between elements of sets can be extended to fuzzy relations. ... ...

Abstract	The concept of fuzzy set, intuitionistic set, and mediative fuzzy set as a generalization of a crisp set have been introduced in many real-life applications. The concept of crisp relation between elements of sets can be extended to fuzzy relations. Extended relations will be considered as relations on fuzzy sets. In this work, we developed the concept of mediative fuzzy relation and meditative fuzzy projection in the context of fuzzy relation and fuzzy projection. We extended the basic operations of fuzzy projection into intuitionistic fuzzy projection and then in the mediative fuzzy projection. We have shown the credibility and impact of mediative index factor involves in the mediative fuzzy projection in context of prediction work in relation to the proposed model. Further, we applied the mediative fuzzy projection in the medical diagnosis in post-COVID-19 patients. The obtained results have also been discussed with their geometrical representation.
Language	English
Publishing date	2022-04-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	1501325-X
ISSN	1879-0755 ; 0045-7906
ISSN (online)	1879-0755
ISSN	0045-7906
DOI	10.1016/j.compeleceng.2022.108028
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Article: Management of Maxillary Sagittal Fracture by using Pre-activated Rapid Maxillary Expansion (RME).

Tiwari, Preeti / Mishra, Nitesh / Rashid, Mohammed / Hirani, Mehul Shashikant

Journal of maxillofacial and oral surgery

2021 Volume 21, Issue 3, Page(s) 759–764

Abstract: Introduction: Different techniques of the management of sagittal maxillary fractures have been described with different advantages and disadvantages. We herein present our experience and results of managing these cases by reversing pre-activated ... ...

Abstract	Introduction: Different techniques of the management of sagittal maxillary fractures have been described with different advantages and disadvantages. We herein present our experience and results of managing these cases by reversing pre-activated maxillary expanders and evaluation of its efficacy. Patient and methods: A prospective study was conducted from April 2016 to February 2020 including all the patients managed for sagittal palatal fractures using the modified technique. The patients were evaluated for healing, occlusion and complications. Results: A total of five patients with sagittal palatal fracture were managed. The mean Glasgow Coma (GCS) score and injury severity score (ISS) of patients were 11.6 ± 2.4 and 15.2 ± 4.3, respectively. Both had a significant strong negative correlation with a correlation coefficient of - 0.889 ( Conclusion: This method could produce enough transversal force to reduce fractured fragments and then serve as an external fixator to maintain stability for bony healing.
Language	English
Publishing date	2021-03-23
Publishing country	India
Document type	Journal Article
ZDB-ID	2502352-4
ISSN	0974-942X ; 0972-8279
ISSN (online)	0974-942X
ISSN	0972-8279
DOI	10.1007/s12663-021-01516-1
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Article: Effects of curcumin on oral cancer at molecular level: A systematic review.

Singh, Akhilesh Kumar / Sharma, Naresh Kumar / Mishra, Nitesh / Mahajan, Arjun / Krishnan, Aswathi / Rajpoot, Ravina / Kumar, Janani Anand / Pandey, Arun

National journal of maxillofacial surgery

2023 Volume 14, Issue 1, Page(s) 9–15

Abstract: This systematic review mainly focuses on the effects of curcumin on oral cancer cells at the molecular level and summarizes the results of the studies. We searched and analyzed various databases such as Pub Med, ProQuest, Google Scholar, Science Direct, ... ...

Abstract	This systematic review mainly focuses on the effects of curcumin on oral cancer cells at the molecular level and summarizes the results of the studies. We searched and analyzed various databases such as Pub Med, ProQuest, Google Scholar, Science Direct, and Scopus. Searches were conducted from 2006 to 2021. This systematic review evaluated various effects of curcumin on oral cancer at the molecular level. All the studies related to the effects of curcumin on oral cancer, both in-vivo and in-vitro, were included. After abstract and text screening a total of 13 articles were finally selected for the study based on the inclusion and exclusion criteria. All most all the included studies reported that after treating the cell lines with curcumin there is a reduction in cell proliferation and cell growth, analyzed using MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide) assay. Curcumin also induces S phase cell cycle arrest and also prevents Tregs migration. The curcumin reverses the process of epithelial mesenchymal transition (EMT) back to mesenchymal epithelial transition (MET). From this review, it is concluded that curcumin inhibited proliferation, migration, invasion, and metastasis, and induced apoptosis via modulating multiple signaling pathways in oral cancer cell lines. But further clinical trials are needed for a detailed evaluation of the effects of curcumin on patients with oral cancer.
Language	English
Publishing date	2023-04-14
Publishing country	India
Document type	Journal Article ; Review
ZDB-ID	2653583-X
ISSN	2229-3418 ; 0975-5950
ISSN (online)	2229-3418
ISSN	0975-5950
DOI	10.4103/njms.njms_29_22
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Article: Investigating the Brain Activity Correlates of Humming Bee Sound during Bhramari Pranayama.

Khajuria, Aayushi / Malan, Nitesh Singh / Bajpai, Rishabh / Kapoor, Dimpy / Mishra, Ashish / Harti, Shivkumar S / Kulkarni, Medha / Joshi, Deepak

Annals of Indian Academy of Neurology

2023 Volume 26, Issue 4, Page(s) 461–468

Abstract: Context: Previous research has shown the vast benefits associated with BhP. However, the dynamics of cortical activity in connection with Bhramari sound have not been investigated yet.: Aim: To investigate the cortical activity in connection with ... ...

Abstract	Context: Previous research has shown the vast benefits associated with BhP. However, the dynamics of cortical activity in connection with Bhramari sound have not been investigated yet. Aim: To investigate the cortical activity in connection with Bhramari sound. Settings and design: Humming sound was analyzed with a custom-made nasal device consisting of MAX4466 sensor time synchronized with the EEG setup. We anticipated that the modulation of cortical activity with the humming sound (either of long or short durations) leaves its effects after the Pranayama, which helps to understand the positive impacts of BhP. Methods and material: 30 participants were instructed to perform the BhP for a period of 90 seconds. We proposed to investigate the cortical correlates before, during, and after the BhP through EEG. A custom-made nasal device consisting of MAX4466 sensor time synchronized with the EEG setup was used for analyzing the humming sound. Statistical analysis used: A paired Results: Results show that the relative spectral power in theta band for short humming durations (less than or equal to 9 seconds) was similar on the frontal cortex during and after the Pranayama practice ( Conclusions: In conclusion, for the immediate positive effects of BhP, the humming duration should be kept less than or equal to 9 seconds. A wearable sound recording system can be developed in the future as a feedback system that provides biofeedback to the user so that a constant humming duration can be maintained.
Language	English
Publishing date	2023-09-11
Publishing country	India
Document type	Journal Article
ZDB-ID	2240174-X
ISSN	1998-3549 ; 0972-2327
ISSN (online)	1998-3549
ISSN	0972-2327
DOI	10.4103/aian.aian_418_23
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Article ; Online: Circadian desynchronization in pregnancy of Golden hamster following long time light exposure: Involvement of Akt/FoxO1 pathway.

Das, Megha / Mohanty, Soumya Ranjan / Minocha, Tarun / Mishra, Nitesh Kumar / Yadav, Sanjeev Kumar / Haldar, Chandana

Journal of photochemistry and photobiology. B, Biology

2022 Volume 234, Page(s) 112508

Abstract: Coordination between central and peripheral reproductive clocks in females is poorly understood. Long light is having a hazardous effect on reproductive health. Hence, explored the effect of long-time light exposure (LLD; 16L:8D) on the central and ... ...

Abstract	Coordination between central and peripheral reproductive clocks in females is poorly understood. Long light is having a hazardous effect on reproductive health. Hence, explored the effect of long-time light exposure (LLD; 16L:8D) on the central and peripheral reproductive (ovary and uterus) clock genes (Bmal1, Clock, Per1, Per2, Cry1 and Cry2) and its downstream regulators (Aanat, Egf, Cx26, Cx43, ERα, pAktS-473, pAktT-308, pFoxO1T-24, 14-3-3, HoxA10, HoxA11 and Pibf) expression in non-pregnant and pregnant Golden hamster. Young adult Golden hamsters were exposed to LLD for 30 days and then were mated. We observed that LLD exposure increased the thickness of the endometrium and reduced myometrium thickness, resembling uterine adenomyosis. In non-pregnant females LLD altered the expressions of clock genes in suprachiasmatic nuclei (SCN), ovary and the uterus along with serum estradiol rhythm. LLD upregulated Egf and downregulated Aanat, Cx26, and Cx43 mRNA levels in uterus. LLD upregulated Akt/FoxO1 phosphorylation and 14-3-3 expressions in the uterus of nonpregnant females. LLD exposure to pregnant females lowered serum progesterone, Aanat, Pibf, Hoxa10, and Hoxa11 mRNA expressions on D4 (peri-implantation) and D8 (post-implantation) resulting in a low implantation rate on D8 (post-implantation). Hence it is evident that the frequent pregnancy anomalies noted under a long light schedule might be due to desynchronization in Aanat, Pibf, Hoxa10, and Hoxa11 as well as the central and peripheral clock genes (Bmal1, Clock, Per1, Per2, Cry1 and Cry2). LLD exposure desynchronized the central and peripheral reproductive clock affecting uterine physiology via Akt/FoxO1 pathway in Golden hamsters. Thus, LLD is a risk factor for female reproductive health and fertility.
MeSH term(s)	ARNTL Transcription Factors ; Animals ; Circadian Rhythm/physiology ; Connexin 43 ; Cricetinae ; Epidermal Growth Factor ; Female ; Mesocricetus ; Pregnancy ; Proto-Oncogene Proteins c-akt ; RNA, Messenger/metabolism
Chemical Substances	ARNTL Transcription Factors ; Connexin 43 ; RNA, Messenger ; Epidermal Growth Factor (62229-50-9) ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1)
Language	English
Publishing date	2022-07-01
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	623022-2
ISSN	1873-2682 ; 1011-1344
ISSN (online)	1873-2682
ISSN	1011-1344
DOI	10.1016/j.jphotobiol.2022.112508
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Article: Systematic Review of Intra Parotid Facial Nerve Schwannoma and a Case Report.

Singh, Akhilesh Kumar / Kumar, Janani Anand / Sharma, Naresh Kumar / Pandey, Arun / Mishra, Nitesh / Bera, Rathindranath

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

2022 Volume 74, Issue Suppl 3, Page(s) 6268–6284

Abstract: To evaluate the clinico-epidemiological aspects, pathological features, diagnostic methods, management protocol and functional outcome of the intra-parotid facial nerve schwannoma (IFNS) and to present a case report on intra parotid facial nerve ... ...

Abstract	To evaluate the clinico-epidemiological aspects, pathological features, diagnostic methods, management protocol and functional outcome of the intra-parotid facial nerve schwannoma (IFNS) and to present a case report on intra parotid facial nerve schwannoma. PubMed, ProQuest, Google scholar, Science direct and Scopus were screened for studies. Article selection and data extraction was done by one investigator and other investigator confirmed its accuracy. After abstract and text screening a total of 69 articles were finally selected for the study with the inclusion and exclusion criteria of the systematic review as per PRISMA guidelines. With addition of one case reported to our department. The mean age of diagnosis was 43 ± 16 years with a slight female predominance. The mean duration of the tumour was 29.5 months and the mean size of the tumour on initial diagnosis was 3.6 ± 1.67 cm. Pleomorphic adenoma was the primary diagnosis in 44 cases. Superficial parotidectomy was done in 64 cases followed by resection in 47 cases. Reconstructive treatment was carried out by an end-to-end anastomosis in 3 patients and by facial-hypoglossal anastomosis in 16 patients, GAN cable grafting in 5 patients, a greater auricular nerve graft was done in18 patients and end-to-side interposed sural nerve graft in 8 patients. The type D tumours are treated by extended resection of the facial nerve, which is difficult to reconstruct and also employs a nerve graft that does not often give acceptable recovery of facial function. Facial nerve schwannomas being a rare entity poses a dilemma in diagnosis and management. Managing the lesions is also difficult as intraoperative adherence to the nerve makes a tumour free margin difficult without sacrificing the nerve. At present there is no consensus regarding the management of various types of intra-parotid facial nerve shwannoma.
Language	English
Publishing date	2022-01-15
Publishing country	India
Document type	Journal Article
ZDB-ID	1471137-0
ISSN	0973-7707 ; 2231-3796 ; 0019-5421
ISSN (online)	0973-7707
ISSN	2231-3796 ; 0019-5421
DOI	10.1007/s12070-021-03013-w
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