LIVIVO - Search results -

Search results

Result 1 - 10 of total 79

Search options

Article ; Online: Genetic variation in the interleukin-28B gene is not associated with fibrosis progression in patients with chronic hepatitis C and known date of infection.

Marabita, Francesco / Aghemo, Alessio / De Nicola, Stella / Rumi, Maria G / Cheroni, Cristina / Scavelli, Rossana / Crimi, Marco / Soffredini, Roberta / Abrignani, Sergio / De Francesco, Raffaele / Colombo, Massimo

Hepatology (Baltimore, Md.)

2011 Volume 54, Issue 4, Page(s) 1127–1134

Abstract: ... and treatment-induced viral clearance in hepatitis C virus (HCV) infection. Nevertheless, it is ...

Abstract	Unlabelled: Polymorphisms in the interleukin-28B (IL28B) region are associated with spontaneous and treatment-induced viral clearance in hepatitis C virus (HCV) infection. Nevertheless, it is unknown whether genetic variation at the IL28B locus influences the natural history of chronic HCV infection. Thus, we asked whether an association between IL28B polymorphisms and liver fibrosis progression existed. We studied 247 consecutive patients with chronic HCV, an accurate estimate of the date of infection, and a liver biopsy performed before any treatment. No patient had a history of alcohol abuse or coinfection with other viruses. We assessed the role of rs8099917 and rs12979860 polymorphisms and the effect of host and environmental factors on fibrosis progression. Blood transfusion (75%) was the main modality of infection. Median age at infection was 21 years, and median interval between infection and liver biopsy was 25 years. One hundred twenty-nine patients (52%) were infected by HCV-1, 74 (30%) by HCV-2, 34 (14%) by HCV-3, and 10 (4%) by HCV-4. Bridging fibrosis/cirrhosis (Ishak ≥ 4) was detected in 24% of patients. Age at infection had a marked effect on fibrosis progression by both a linear model and Cox proportional-hazard regression (P < 2E-16). A 12.1% increase in the hazard of advanced fibrosis was estimated for each additional year at infection, suggesting that this was the major explanatory variable in this cohort. Male gender (P < 0.05), HCV genotype 3 (P < 0.001) and steatosis (P < 0.05) were also associated with faster fibrosis progression. Conversely, the two IL28B polymorphisms had no impact on fibrosis progression. Conclusion: In HCV patients with a known date of infection, IL28B genotype was not associated with fibrosis progression rate or with the risk of developing advanced liver fibrosis.
MeSH term(s)	Adult ; Age Distribution ; Age of Onset ; Cohort Studies ; Disease Progression ; Female ; Follow-Up Studies ; Genetic Variation ; Genotype ; Hepatitis C, Chronic/epidemiology ; Hepatitis C, Chronic/genetics ; Hepatitis C, Chronic/pathology ; Humans ; Interferons ; Interleukins/genetics ; Linear Models ; Liver Cirrhosis/epidemiology ; Liver Cirrhosis/genetics ; Liver Cirrhosis/pathology ; Liver Cirrhosis/virology ; Male ; Middle Aged ; Proportional Hazards Models ; Severity of Illness Index ; Sex Distribution ; Young Adult
Chemical Substances	interferon-lambda, human ; Interleukins ; Interferons (9008-11-1)
Language	English
Publishing date	2011-08-19
Publishing country	United States
Document type	Comparative Study ; Journal Article
ZDB-ID	604603-4
ISSN	1527-3350 ; 0270-9139
ISSN (online)	1527-3350
ISSN	0270-9139
DOI	10.1002/hep.24503
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 1660: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾

Article ; Online: A strange case of Transthyretin Cardiac Amyloidosis in the Elderly: a diagnostic challenge.

Simeone, B / Zuchi, C / Mengoni, A / Carluccio, E / Biagioli, P / Lauciello, R / Sasso, G / Scavelli, F / Rocco, E / Ambrosio, G

La Clinica terapeutica

2023 Volume 174, Issue 3, Page(s) 235–239

Abstract: Abstract: Transthyretin (TTR)-related cardiac amyloidosis is a progressive infiltrative cardiomyopathy that mimics hypertensive, hypertrophic heart disease and may go undiagnosed. We here report the case of a 83-year-old woman, which has rapresented an ... ...

Abstract	Abstract: Transthyretin (TTR)-related cardiac amyloidosis is a progressive infiltrative cardiomyopathy that mimics hypertensive, hypertrophic heart disease and may go undiagnosed. We here report the case of a 83-year-old woman, which has rapresented an unique case of transthyretin-related cardiac amyloidosis, as a patient with an initial diagnosis of hypertensive heart disease later develops an infiltrative cardiomyopathy due to amyloid deposits.
MeSH term(s)	Aged, 80 and over ; Female ; Humans ; Amyloidosis/complications ; Amyloidosis/diagnosis ; Cardiomyopathies/diagnosis ; Cardiomyopathies/etiology ; Heart Diseases ; Hypertension ; Prealbumin
Chemical Substances	Prealbumin
Language	English
Publishing date	2023-10-27
Publishing country	Italy
Document type	Case Reports ; Journal Article
ZDB-ID	123320-8
ISSN	1972-6007 ; 0009-9074
ISSN (online)	1972-6007
ISSN	0009-9074
DOI	10.7417/CT.2023.2526
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 98: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Autoimmune thyroiditis and celiac disease do not worsen endothelial function in subjects with type 1 diabetes: an observational study.

Parise, Martina / Cutruzzolà, Antonio / Scavelli, Faustina Barbara / Carallo, Claudio / Gnasso, Agostino / Irace, Concetta

Diabetology & metabolic syndrome

2022 Volume 14, Issue 1, Page(s) 103

Abstract: Background: Type 1 diabetes (T1D) is frequently associated with autoimmune thyroiditis (AT) and coeliac disease (CD). Whether the coexistence of multiple autoimmune diseases increases cardiovascular risk is uncertain. We evaluated the effects of AT and ... ...

Abstract	Background: Type 1 diabetes (T1D) is frequently associated with autoimmune thyroiditis (AT) and coeliac disease (CD). Whether the coexistence of multiple autoimmune diseases increases cardiovascular risk is uncertain. We evaluated the effects of AT and CD on arterial wall thickening and endothelial function in patients with T1D. Methods: This observational study analyzed data from T1D patients regularly followed by the Diabetes Care Centre. Clinical and biochemical characteristics and micro and macrovascular complications were collected from the electronic medical records. All subjects performed Echo-Doppler to evaluate Intima-Media Thickness (IMT) of the common carotid artery (CCA) and endothelial function by the flow-mediated dilation (FMD) technique. The statistical analyses were performed by SPSS for Macintosh. Comparison between means was performed using the t-test for unpaired data and the Mann-Whitney U test. The ANalysis Of VAriance and the Tukey posthoc test were applied to compare patients with and without other autoimmune diseases, and control subjects. The p-value for statistical significance was set at p < 0.05. Results: A total of 110 patients were enrolled. Among these, 69 had T1D and 41 T1D and AT and or CD, of whom 33 AT, 7 CD, and 1 both AT and CD. The mean age was 35 years, mean HbA1c was 7.6%, and mean diabetes duration 18 years. The IMT of the CCA was not significantly different between T1D patients with and without concomitant autoimmune diseases (with AT and CD: right CCA 603 ± 186 µ, left 635 ± 175 µ; without AT and CD: right CCA 611 ± 176 µ, left CCA 631 ± 200 µ). FMD was also comparable between T1D groups, with AT and CD 7.9 ± 4.2%; without AT and CD 8.8 ± 4.4%. Conclusion: Patients with T1D and concomitant AT and or CD show no worse morphological or functional vascular damage, evaluated by CCA IMT and brachial artery flow-mediated dilation, than patients with T1D alone.
Language	English
Publishing date	2022-07-23
Publishing country	England
Document type	Journal Article
ZDB-ID	2518786-7
ISSN	1758-5996
ISSN	1758-5996
DOI	10.1186/s13098-022-00877-y
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Time in Range Does Not Associate With Carotid Artery Wall Thickness and Endothelial Function in Type 1 Diabetes.

Cutruzzolà, Antonio / Parise, Martina / Scavelli, Faustina B / Barone, Milena / Gnasso, Agostino / Irace, Concetta

Journal of diabetes science and technology

2021 Volume 16, Issue 4, Page(s) 904–911

Abstract: Background: Patients with Type 1 diabetes (T1D) have an increased risk of developing atherosclerosis and complications as myocardial infarction and peripheral artery disease. The thickening of the carotid wall and the brachial artery dysfunction are ... ...

Abstract	Background: Patients with Type 1 diabetes (T1D) have an increased risk of developing atherosclerosis and complications as myocardial infarction and peripheral artery disease. The thickening of the carotid wall and the brachial artery dysfunction are early and preclinical manifestations of atherosclerosis. The standard marker of care for assessment of glycemic control, glycated hemoglobin, does not associate with early atherosclerosis. We have hypothesized that the emerging metric of glycemic control, as the time spent in the target range (TIR), might be associated with carotid thickening and endothelial dysfunction. According to the hypothesis, we have designed the present research with the aim to evaluate the association between TIR collected in the short and long term and the measures of arterial morphology and function in patients with T1D. Methods: In our study, 70 patients and 35 healthy controls underwent ultrasound vascular study to measure carotid artery intima-media thickness (IMT) and brachial artery endothelial function by the flow-mediated dilation (FMD) technique. TIR was collected by a continuous glucose monitoring system for 2 weeks, 3 months, and 6 months before the vascular study. Results: Patients with T1D showed a significantly higher carotid IMT (mean±SE, 644±19 vs. 568±29 µ; Conclusions: Young patients with T1D have early vascular abnormalities. The percent of TIR does not correlate with preclinical atherosclerosis. This finding underlines the complexity of the interplay between diabetes and atherosclerosis.
MeSH term(s)	Atherosclerosis/etiology ; Blood Glucose ; Blood Glucose Self-Monitoring/adverse effects ; Carotid Arteries/diagnostic imaging ; Carotid Intima-Media Thickness ; Diabetes Mellitus, Type 1/complications ; Endothelium, Vascular/diagnostic imaging ; Humans ; Ultrasonography/adverse effects ; Vasodilation
Chemical Substances	Blood Glucose
Language	English
Publishing date	2021-02-22
Publishing country	United States
Document type	Journal Article
ISSN	1932-2968
ISSN (online)	1932-2968
DOI	10.1177/1932296821993178
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- Full text online
- Order with fees

Article: Percutaneous Coronary Revascularization after Out-of-Hospital Cardiac Arrest: A Review of the Literature and a Case Series.

Scavelli, Francesca / Cartella, Iside / Montalto, Claudio / Oreglia, Jacopo Andrea / Villanova, Luca / Garatti, Laura / Colombo, Claudia / Sacco, Alice / Morici, Nuccia

Journal of clinical medicine

2022 Volume 11, Issue 5

Abstract: Out-of-hospital cardiac arrest (OHCA) is still associated with high mortality and severe complications, despite major treatment advances in this field. Ischemic heart disease is a common cause of OHCA, and current guidelines clearly recommend performing ... ...

Abstract	Out-of-hospital cardiac arrest (OHCA) is still associated with high mortality and severe complications, despite major treatment advances in this field. Ischemic heart disease is a common cause of OHCA, and current guidelines clearly recommend performing immediate coronary angiography (CAG) in patients whose post-resuscitation electrocardiogram shows ST-segment elevation (STE). Contrarily, the optimal approach and the advantage of early revascularization in cases of no STE is less clear, and decisions are often based on the individual experience of the center. Numerous studies have been conducted on this topic and have provided contradictory evidence; however, more recently, results from several randomized clinical trials have suggested that performing early CAG has no impact on overall survival in patients without STE.
Language	English
Publishing date	2022-03-03
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm11051395
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: The effect of antithrombotic treatment on mortality in patients with acute infection: A meta-analysis of randomized clinical trials.

Gazzaniga, Gianluca / Tavecchia, Giovanni Amedeo / Bravi, Francesca / Scavelli, Francesca / Travi, Giovanna / Campo, Gianluca / Vandenbriele, Christophe / Tritschler, Tobias / Sterne, Jonathan A C / Murthy, Srinivas / Morici, Nuccia

International journal of cardiology

2023 Volume 383, Page(s) 75–81

Abstract: Background and aims: Acute infections cause relevant activation of innate immunity and inflammatory cascade. An excessive response against pathogens has been proved to trigger the pathophysiological process of thrombo-inflammation. Nevertheless, an ... ...

Abstract	Background and aims: Acute infections cause relevant activation of innate immunity and inflammatory cascade. An excessive response against pathogens has been proved to trigger the pathophysiological process of thrombo-inflammation. Nevertheless, an association between the use of antithrombotic agents and the outcome of critically ill patients with infectious diseases is lacking. The aim of this meta-analysis is to determine the impact of antithrombotic treatment on survival of patients with acute infective disease. Methods: MEDLINE, Embase, Cinahl, Web of Science and Cochrane Central Register of Controlled Trials (CENTRAL) databases were systematically searched from inception to March 2021. We included randomized controlled trials (RCTs) that evaluated any antithrombotic agent in patients with infectious diseases other than COVID-19. Two authors independently performed study selection, data extraction and risk of bias evaluation. The primary outcome was all-cause mortality. Summary estimates for mortality were calculated using the inverse-variance random-effects method. Results: A total of 16,588 patients participating in 18 RCTs were included, of whom 2141 died. Four trials evaluated therapeutic-dose anticoagulation, 1 trial prophylactic-dose anticoagulation, 4 trials aspirin, and 9 trials other antithrombotic agents. Overall, the use of antithrombotic agents was not associated with all-cause mortality (relative risk 0.96; 95% confidence interval, 0.90-1.03). Conclusions: The use of antithrombotics is not associated with all-cause mortality in patients with infectious disease other than COVID-19. Complex pathophysiological interplays between inflammatory and thrombotic pathways may explain these results and need further investigation. Registration: PROSPERO, CRD42021241182.
MeSH term(s)	Humans ; Anticoagulants/adverse effects ; Aspirin ; COVID-19 ; Fibrinolytic Agents/therapeutic use ; Randomized Controlled Trials as Topic
Chemical Substances	Anticoagulants ; Aspirin (R16CO5Y76E) ; Fibrinolytic Agents
Language	English
Publishing date	2023-05-04
Publishing country	Netherlands
Document type	Journal Article ; Meta-Analysis
ZDB-ID	779519-1
ISSN	1874-1754 ; 0167-5273
ISSN (online)	1874-1754
ISSN	0167-5273
DOI	10.1016/j.ijcard.2023.04.057
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1673: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Long-term efficacy and safety of a third-line treatment with eribulin plus trastuzumab in a young breast cancer patient.

Scavelli, Claudio / Gallù, Federica

Future oncology (London, England)

2014 Volume 10, Issue 14, Page(s) 2127–2132

Abstract: Eribulin mesylate is approved for the treatment of metastatic breast cancer (MBC) patients after progression with anthracyclines and taxanes. Eribulin appears especially promising when combined with trastuzumab, according to the results of a recent Phase ...

Abstract	Eribulin mesylate is approved for the treatment of metastatic breast cancer (MBC) patients after progression with anthracyclines and taxanes. Eribulin appears especially promising when combined with trastuzumab, according to the results of a recent Phase II trial in first-line setting. Here we report the case of a young, pretreated, HER2(-) MBC patient, who achieved a long-term clinical benefit with eribulin alone and in combination with trastuzumab after re-biopsy on liver metastases showed HER2 amplification. Although it is unique for its evolving clinical/biomolecular picture, this case adds anecdotal evidence to the efficacy and tolerability of this combination. However, Phase III trials are warranted to confirm its potential in first and subsequent lines of MBC treatment.
MeSH term(s)	Adult ; Antibodies, Monoclonal, Humanized/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Breast Neoplasms/diagnosis ; Breast Neoplasms/drug therapy ; Female ; Furans/administration & dosage ; Humans ; Ketones/administration & dosage ; Liver Neoplasms/diagnosis ; Liver Neoplasms/secondary ; Lung Neoplasms/diagnosis ; Lung Neoplasms/secondary ; Retreatment ; Tomography, X-Ray Computed ; Trastuzumab ; Treatment Outcome
Chemical Substances	Antibodies, Monoclonal, Humanized ; Furans ; Ketones ; eribulin (LR24G6354G) ; Trastuzumab (P188ANX8CK)
Language	English
Publishing date	2014-11
Publishing country	England
Document type	Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2184533-5
ISSN	1744-8301 ; 1479-6694
ISSN (online)	1744-8301
ISSN	1479-6694
DOI	10.2217/fon.14.134
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

Order via subito

Details ▾
- Full text online
- Order with fees

Article ; Online: Effect of a quality-improvement intervention on end-of-life care in cardiac intensive care unit.

Sacco, Alice / Tavecchia, Giovanni / Ditali, Valentina / Garatti, Laura / Villanova, Luca / Colombo, Claudia / Viola, Giovanna / Scavelli, Francesca / Varrenti, Marisa / Milani, Martina / Morici, Nuccia / Tavazzi, Guido / Lissoni, Barbara / Forni, Lorena / Gorni, Giovanna / Saporetti, Giorgia / Oliva, Fabrizio

European journal of clinical investigation

2023 Volume 53, Issue 7, Page(s) e13982

MeSH term(s)	Humans ; Terminal Care ; Intensive Care Units ; Quality Improvement
Language	English
Publishing date	2023-03-20
Publishing country	England
Document type	Letter
ZDB-ID	186196-7
ISSN	1365-2362 ; 0014-2972 ; 0960-135X
ISSN (online)	1365-2362
ISSN	0014-2972 ; 0960-135X
DOI	10.1111/eci.13982
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 677: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Risk factors and outcome in dogs with recurrent massive hepatocellular carcinoma: A Veterinary Society of Surgical Oncology case-control study.

Lapsley, Janis M / Wavreille, Vincent / Barry, Sabrina / Dornbusch, Josephine A / Chen, Carolyn / Leeper, Haley / Bertran, Judith / Scavelli, Diane / Liptak, Julius M / Wood, Chris / Shamir, Shelly / Rosenbaum, Claire / Montinaro, Vincenzo / Wustefeld-Janssens, Brandan / Sterman, Allyson / Chik, Colin / Singh, Ameet / Collins, Josh / Selmic, Laura E

Veterinary and comparative oncology

2022 Volume 20, Issue 3, Page(s) 697–709

Abstract: Local recurrence after surgical excision of canine massive hepatocellular carcinoma (HCC) has been poorly studied in veterinary medicine with scant information published regarding risk factors for and outcome following recurrence. The aim of this case- ... ...

Abstract	Local recurrence after surgical excision of canine massive hepatocellular carcinoma (HCC) has been poorly studied in veterinary medicine with scant information published regarding risk factors for and outcome following recurrence. The aim of this case-control study was to describe the time to recurrence, evaluate potential risk factors for recurrence, and report the outcome in dogs with massive HCC. Medical records for 75 dogs who developed recurrence and 113 dogs who did not develop recurrence were reviewed. Statistical analyses were performed to determine risk factors for recurrence as well as the median time to develop recurrence and overall survival time (OS). None of the risk factors evaluated were significant for the development of recurrence. The median time to develop recurrence was 367 days (range 32-2096 days). There was no significant difference in median OS for dogs who developed recurrence vs. those who did not (851 vs. 970 days). For dogs with recurrent HCC, treatment at recurrence trended toward prolonged OS but was not significantly different from dogs not undergoing treatment at recurrence. There was no significant difference in median OS for dogs with histologically complete vs. incomplete tumour excision (990 vs. 903 days). Although specific risk factors for recurrence were not identified, elevations in liver values were noted in patients with recurrent disease and could act as a noninvasive surveillance tool. Recurrence was noted earlier in dogs who had routine post-operative surveillance (228 vs. 367 days). Routine surveillance for recurrence is recommended especially in dogs where further intervention is possible and should extend beyond 1 year. Patients with massive HCC have a good long-term prognosis regardless of incomplete excision, pulmonary metastasis, or recurrent local disease.
MeSH term(s)	Animals ; Carcinoma, Hepatocellular/surgery ; Carcinoma, Hepatocellular/veterinary ; Case-Control Studies ; Dog Diseases/surgery ; Dogs ; Liver Neoplasms/surgery ; Liver Neoplasms/veterinary ; Neoplasm Recurrence, Local/surgery ; Neoplasm Recurrence, Local/veterinary ; Prognosis ; Retrospective Studies ; Risk Factors ; Societies, Veterinary ; Surgical Oncology ; Treatment Outcome
Language	English
Publishing date	2022-05-15
Publishing country	England
Document type	Journal Article
ZDB-ID	2129634-0
ISSN	1476-5829 ; 1476-5810
ISSN (online)	1476-5829
ISSN	1476-5810
DOI	10.1111/vco.12824
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

Order via subito

Details ▾
- Full text online
- Order with fees

Article ; Online: Body fat and blood rheology: Evaluation of the association between different adiposity indices and blood viscosity.

Tripolino, Cesare / Irace, Concetta / Carallo, Claudio / Scavelli, Faustina Barbara / Gnasso, Agostino

Clinical hemorheology and microcirculation

2017 Volume 65, Issue 3, Page(s) 241–248

Abstract: Background: In recent years, new measures of body adiposity have been introduced: lipid accumulation product (LAP), body adiposity index (BAI) and body shape index (ABSI). These indices have been demonstrated to better associate with cardiovascular ... ...

Abstract	Background: In recent years, new measures of body adiposity have been introduced: lipid accumulation product (LAP), body adiposity index (BAI) and body shape index (ABSI). These indices have been demonstrated to better associate with cardiovascular disease than other measures of adiposity. Objectives: The aim of the present study was to evaluate if LAP or BAI better associate with blood viscosity than other measures of adiposity (body mass index, BMI; waist circumference, WC; waist-to-hip ratio, W/HR; waist-to-height ratio, W/HtR). Methods: 344 subjects were recruited for the present investigation. Exclusion criteria were: diabetes, elevated triglycerides, smoking and drug use. Blood lipids and glucose were measured by routine methods. Blood and plasma viscosity were measured by a cone-plate viscometer. Adiposity measures were computed as previously described. Results: In simple correlation analyses, blood viscosity (BV) correlated with BMI, BAI, and LAP in males and with LAP in females. Correlations between plasma viscosity and adiposity indices were weak and not statistically significant. Other variables significantly related with BV were: gender, HDL- and LDL-Cholesterol, and triglycerides (p < 0.05). In multiple regression analysis only LAP was associated with BV. Conclusions: Our data suggest that LAP index is strongly associated to blood viscosity. This result, along with previous evidence, identifies LAP index as a potential cardiovascular risk marker.
MeSH term(s)	Adipose Tissue/metabolism ; Adiposity/physiology ; Blood Viscosity/physiology ; Cross-Sectional Studies ; Female ; Humans ; Male ; Middle Aged ; Obesity/complications ; Rheology ; Risk Factors
Language	English
Publishing date	2017
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1381750-4
ISSN	1875-8622 ; 1386-0291
ISSN (online)	1875-8622
ISSN	1386-0291
DOI	10.3233/CH-16172
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1623: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito