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  1. Article ; Online: Letter to the Editor on "A randomized trial on the effectiveness and safety of 5 water-based personal lubricants".

    Brown, Sarah E / Brotman, Rebecca M

    The journal of sexual medicine

    2023  Volume 20, Issue 10, Page(s) 1257

    MeSH term(s) Humans ; Lubricants ; Water
    Chemical Substances Lubricants ; Water (059QF0KO0R)
    Language English
    Publishing date 2023-08-07
    Publishing country Netherlands
    Document type Randomized Controlled Trial ; Research Support, N.I.H., Extramural ; Letter ; Comment
    ZDB-ID 2251959-2
    ISSN 1743-6109 ; 1743-6095
    ISSN (online) 1743-6109
    ISSN 1743-6095
    DOI 10.1093/jsxmed/qdad077
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    Zs.A 6417: Show issues Location:
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  2. Article ; Online: Photochemical Reduction of Quinolines with γ-Terpinene.

    Adak, Souvik / Braley, Sarah E / Brown, M Kevin

    Organic letters

    2024  Volume 26, Issue 1, Page(s) 401–405

    Abstract: The saturation of aromatic scaffolds is valuable for the synthesis of complex rings. Herein, we demonstrate a process for photochemical dearomative reduction of quinolines. The process involves capture of a quinoline excited state with γ-terpinene. ... ...

    Abstract The saturation of aromatic scaffolds is valuable for the synthesis of complex rings. Herein, we demonstrate a process for photochemical dearomative reduction of quinolines. The process involves capture of a quinoline excited state with γ-terpinene. Importantly, the reaction is chemoselective as other easily reduced functionalities such as halogens or alkenes do not undergo reduction. The mechanism of the reaction has also been investigated. Finally, the generality of the approach towards other substrates is demonstrated.
    Language English
    Publishing date 2024-01-03
    Publishing country United States
    Document type Journal Article
    ISSN 1523-7052
    ISSN (online) 1523-7052
    DOI 10.1021/acs.orglett.3c04096
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  3. Article ; Online: Quantitative Assay of Fentanyl and Analogs Using LC-MS/MS.

    Brown, Hannah M / Riley, Sarah B

    Methods in molecular biology (Clifton, N.J.)

    2023  Volume 2737, Page(s) 283–295

    Abstract: Drug overdoses and drug-involved deaths continue to increase in the United States, with most drug overdose deaths involving opioids. Among drug overdose deaths, opioids, particularly fentanyl and its analogs, remain the most prevalent substances involved. ...

    Abstract Drug overdoses and drug-involved deaths continue to increase in the United States, with most drug overdose deaths involving opioids. Among drug overdose deaths, opioids, particularly fentanyl and its analogs, remain the most prevalent substances involved. Despite the increase in the recreational use of fentanyl analogs and their role in drug overdoses, fentanyl and its analogs are not commonly included in clinical drug testing panels due to the need for specialized testing platforms. To address this, a rapid, robust, and accurate LC-MS/MS method for the quantitation of fentanyl and fentanyl analogs was developed. Identification and quantitation of each analyte was made using multiple reaction monitoring (MRM) with two transitions, along with the corresponding deuterated internal standard for each analyte for accurate measurement.
    MeSH term(s) Humans ; United States ; Fentanyl ; Chromatography, Liquid ; Tandem Mass Spectrometry ; Analgesics, Opioid ; Drug Overdose/diagnosis
    Chemical Substances Fentanyl (UF599785JZ) ; Analgesics, Opioid
    Language English
    Publishing date 2023-12-01
    Publishing country United States
    Document type Journal Article
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-3541-4_26
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  4. Article ; Online: Why did I eat that? Understanding the 'why' of compulsive behaviour towards food.

    Brown, Robyn M / Ch'ng, Sarah S / Davis, Caroline C

    Progress in neuro-psychopharmacology & biological psychiatry

    2023  Volume 127, Page(s) 110803

    MeSH term(s) Compulsive Behavior ; Anger ; Food
    Language English
    Publishing date 2023-05-26
    Publishing country England
    Document type Editorial
    ZDB-ID 781181-0
    ISSN 1878-4216 ; 0278-5846
    ISSN (online) 1878-4216
    ISSN 0278-5846
    DOI 10.1016/j.pnpbp.2023.110803
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    Zs.A 1342: Show issues Location:
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  5. Article ; Online: Implementation of preductal and postductal oxygen saturation screening in babies born in a district general hospital.

    Reid, Emma S / Leiter, Sarah M / Silverwood, Holly / Cunnington, Amy / Ranson, Karen / Brown, Jacqueline / Noone, Martina

    Archives of disease in childhood. Education and practice edition

    2024  

    Language English
    Publishing date 2024-02-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2148818-6
    ISSN 1743-0593 ; 1743-0585
    ISSN (online) 1743-0593
    ISSN 1743-0585
    DOI 10.1136/archdischild-2023-325304
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  6. Article ; Online: Items Outperform Adjectives in a Computational Model of Binary Semantic Classification.

    Diachek, Evgeniia / Brown-Schmidt, Sarah / Polyn, Sean M

    Cognitive science

    2023  Volume 47, Issue 9, Page(s) e13336

    Abstract: Semantic memory encompasses one's knowledge about the world. Distributional semantic models, which construct vector spaces with embedded words, are a proposed framework for understanding the representational structure of human semantic knowledge. Unlike ... ...

    Abstract Semantic memory encompasses one's knowledge about the world. Distributional semantic models, which construct vector spaces with embedded words, are a proposed framework for understanding the representational structure of human semantic knowledge. Unlike some classic semantic models, distributional semantic models lack a mechanism for specifying the properties of concepts, which raises questions regarding their utility for a general theory of semantic knowledge. Here, we develop a computational model of a binary semantic classification task, in which participants judged target words for the referent's size or animacy. We created a family of models, evaluating multiple distributional semantic models, and mechanisms for performing the classification. The most successful model constructed two composite representations for each extreme of the decision axis (e.g., one averaging together representations of characteristically big things and another of characteristically small things). Next, the target item was compared to each composite representation, allowing the model to classify more than 1,500 words with human-range performance and to predict response times. We propose that when making a decision on a binary semantic classification task, humans use task prompts to retrieve instances representative of the extremes on that semantic dimension and compare the probe to those instances. This proposal is consistent with the principles of the instance theory of semantic memory.
    MeSH term(s) Humans ; Semantics ; Knowledge ; Memory ; Reaction Time ; Computer Simulation
    Language English
    Publishing date 2023-09-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2002940-8
    ISSN 1551-6709 ; 0364-0213
    ISSN (online) 1551-6709
    ISSN 0364-0213
    DOI 10.1111/cogs.13336
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  7. Article ; Online: Hospital Facility Prices Declined As A Result Of Oregon's Hospital Payment Cap.

    Murray, Roslyn C / Brown, Zach Y / Miller, Sarah / Norton, Edward C / Ryan, Andrew M

    Health affairs (Project Hope)

    2024  Volume 43, Issue 3, Page(s) 424–432

    Abstract: Hospital prices for commercially insured people are high and vary widely, prompting states to seek ways to control hospital price growth. In October 2019, the Oregon state employee health insurance plan instituted a cap on hospital payments. Using 2014- ... ...

    Abstract Hospital prices for commercially insured people are high and vary widely, prompting states to seek ways to control hospital price growth. In October 2019, the Oregon state employee health insurance plan instituted a cap on hospital payments. Using 2014-21 data from the Oregon All Payer All Claims Reporting Program database, we performed a difference-in-differences analysis to test the impact of the cap on hospital facility prices for Oregon's state employee plan enrollees. We found that the cap was not associated with a significant reduction in inpatient facility prices across the post period (-$901.9 per admission) but was associated with a significant reduction in the second year after implementation (-$2,774.20). The cap was associated with a significant reduction in outpatient facility prices over the course of the first twenty-seven months of the policy (-$130.50 per procedure). We estimated $107.5 million (or 4 percent of total plan spending) in savings to the state employee plan during the first two years. The hospital payment cap successfully reduced hospital prices for enrollees in that plan.
    MeSH term(s) Humans ; Oregon ; Hospitals ; Hospitalization ; Databases, Factual ; Income
    Language English
    Publishing date 2024-03-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632712-6
    ISSN 1544-5208 ; 0278-2715
    ISSN (online) 1544-5208
    ISSN 0278-2715
    DOI 10.1377/hlthaff.2023.01021
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    Zs.A 2118: Show issues Location:
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  8. Article ; Online: Commentary.

    Brown, Sarah M

    Clinical chemistry

    2016  Volume 62, Issue 12, Page(s) 1569

    Language English
    Publishing date 2016-11-28
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 80102-1
    ISSN 1530-8561 ; 0009-9147
    ISSN (online) 1530-8561
    ISSN 0009-9147
    DOI 10.1373/clinchem.2016.263574
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    Ud II Zs.171: Show issues Location:
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  9. Article ; Online: Antarctic Evacuation: A Retrospective Epidemiological Study of Medical Evacuations on US Military Aircraft in Antarctica.

    Brown, Samuel P / Mongold, Sarah M / Powell, Thomas L / Goss, Sarah E / Schauer, Steven G

    Medical journal (Fort Sam Houston, Tex.)

    2023  , Issue Per 23-1/2/3, Page(s) 41–46

    Abstract: Background: The international community has shown increasing interest in the Arctic and Antarctic due to the value polar regions have in terms of environmental research, natural resources, and national defense. The US Government maintains several ... ...

    Abstract Background: The international community has shown increasing interest in the Arctic and Antarctic due to the value polar regions have in terms of environmental research, natural resources, and national defense. The US Government maintains several permanent research and military facilities in polar regions. Medical evacuation (MEDEVAC) from these facilities can be limited for prolonged periods of time due to their extreme climates. Published data regarding MEDEVACs from these facilities is extremely limited.
    Methods: Evacuations on military aircraft registered in the Transportation Command Regulation and Command and Control Evacuation System (TRAC2ES) database in a previously de-identified dataset were queried for events from McMurdo, Antarctica. The data was analyzed to determine the number of evacuations, reasons for evacuation, and additional demographic data.
    Results: There were 31 evacuations from McMurdo Station and Scott Amundsen South Pole Station for 29 unique patients recorded in the available TRAC2ES dataset. Reasons for evacuation included traumatic brain/head injury, behavioral health concerns, extremity injuries, pregnancy, and various other medical/surgical concerns.
    Conclusions: MEDEVAC was typically required for advanced diagnostic/treatment modalities or if a patient could no longer fulfill his/her duties. Most evacuations were not directly related to environmental exposure. Given the climate in polar regions can preclude timely evacuation for large periods of time, the need for evacuation must be anticipated and mitigated whenever possible. Better data is needed to guide staffing and mission planning in this remote location.
    MeSH term(s) Humans ; Male ; Female ; Antarctic Regions ; Military Personnel ; Retrospective Studies ; Aircraft ; Transportation of Patients ; Brain Injuries, Traumatic
    Language English
    Publishing date 2023-01-06
    Publishing country United States
    Document type Journal Article
    ISSN 2694-3611
    ISSN (online) 2694-3611
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  10. Article ; Online: Exploring the use of experimental small area estimates to examine the relationship between individual-level and area-level community belonging and self-rated health.

    Mah, Sarah M / Brown, Mark / Colley, Rachel C / Rosella, Laura C / Schellenberg, Grant / Sanmartin, Claudia

    Health reports

    2024  Volume 35, Issue 3, Page(s) 3–17

    Abstract: Background: Small area estimation refers to statistical modelling procedures that leverage information or "borrow strength" from other sources or variables. This is done to enhance the reliability of estimates of characteristics or outcomes for areas ... ...

    Abstract Background: Small area estimation refers to statistical modelling procedures that leverage information or "borrow strength" from other sources or variables. This is done to enhance the reliability of estimates of characteristics or outcomes for areas that do not contain sufficient sample sizes to provide disaggregated estimates of adequate precision and reliability. There is growing interest in secondary research applications for small area estimates (SAEs). However, it is crucial to assess the analytic value of these estimates when used as proxies for individual-level characteristics or as distinct measures that offer insights at the area level. This study assessed novel area-level community belonging measures derived using small area estimation and examined associations with individual-level measures of community belonging and self-rated health.
    Data and methods: SAEs of community belonging within census tracts produced from the 2016-2019 cycles of the Canadian Community Health Survey (CCHS) were merged with respondent data from the 2020 CCHS. Multinomial logistic regression models were run between area-level SAEs, individual-level sense of community belonging, and self-rated health on the study sample of people aged 18 years and older.
    Results: Area-level community belonging was associated with individual-level community belonging, even after adjusting for individual-level sociodemographic characteristics, despite limited agreement between individual- and area-level measures. Living in a neighbourhood with low community belonging was associated with higher odds of reporting being in fair or poor health, versus being in very good or excellent health (odds ratio: 1.53; 95% confidence interval: 1.22, 1.91), even after adjusting for other factors such as individual-level sense of community belonging, which was also associated with self-rated health.
    Interpretation: Area-level and individual-level sense of community belonging were independently associated with self-rated health. The novel SAEs of community belonging can be used as distinct measures of neighbourhood-level community belonging and should be understood as complementary to, rather than proxies for, individual-level measures of community belonging.
    MeSH term(s) Humans ; Socioeconomic Factors ; Health Status ; Reproducibility of Results ; Canada ; Health Surveys ; Residence Characteristics
    Language English
    Publishing date 2024-03-25
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 1057245-4
    ISSN 1209-1367 ; 0840-6529
    ISSN (online) 1209-1367
    ISSN 0840-6529
    DOI 10.25318/82-003-x202400300001-eng
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    Zs.A 3470: Show issues Location:
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