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Article ; Online: Retention of Virus Versus Surrogate, by Ultrafiltration in Seawater: Case Study of Norovirus Versus Tulane.

Monnot, M / Ollivier, J / Taligrot, H / Garry, P / Cordier, C / Stravakakis, C / Le Guyader, F S / Moulin, P

2024 Volume 16, Issue 1, Page(s) 14–24

Abstract: In the field of chemical engineering and water treatment, the study of viruses, included surrogates, is well documented. Often, surrogates are used to study viruses and their behavior because they can be produced in larger quantities in safer conditions ... ...

Abstract	In the field of chemical engineering and water treatment, the study of viruses, included surrogates, is well documented. Often, surrogates are used to study viruses and their behavior because they can be produced in larger quantities in safer conditions and are easier to handle. In fact, surrogates allow studying microorganisms which are non-infectious to humans but share some properties similar to pathogenic viruses: structure, composition, morphology, and size. Human noroviruses, recognized as the leading cause of epidemics and sporadic cases of gastroenteritis across all age groups, may be mimicked by the Tulane virus. The objectives of this work were to study (i) the ultrafiltration of Tulane virus and norovirus to validate that Tulane virus can be used as a surrogate for norovirus in water treatment process and (ii) the retention of norovirus and the surrogate as a function of water quality to better understand the use of the latter pathogenic viruses. Ultrafiltration tests showed significant logarithmic reduction values (LRV) in viral RNA: around 2.5 for global LRV (i.e., based on the initial and permeate average concentrations) and between 2 and 6 for average LRV (i.e., retention rate considering the increase of viral concentration in the retentate), both for norovirus and the surrogate Tulane virus. Higher reduction rates (from 2 to 6 log genome copies) are obtained for higher initial concentrations (from 10
MeSH term(s)	Humans ; Norovirus/genetics ; Ultrafiltration ; Gastroenteritis ; RNA, Viral/genetics ; Seawater ; Virus Inactivation
Chemical Substances	RNA, Viral
Language	English
Publishing date	2024-01-06
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2487173-4
ISSN	1867-0342 ; 1867-0334
ISSN (online)	1867-0342
ISSN	1867-0334
DOI	10.1007/s12560-023-09574-z
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Article ; Online: Diethylnitrosamine-Induced Liver Tumorigenesis in Mice Under High-Hat High-Sucrose Diet: Stepwise High-Resolution Ultrasound Imaging and Histopathological Correlations.

Cordier, Pierre / Sangouard, Flora / Fang, Jing / Kabore, Christelle / Desdouets, Chantal / Celton-Morizur, Séverine

Methods in molecular biology (Clifton, N.J.)

2024 Volume 2769, Page(s) 27–55

Abstract: The hepatotoxic N-nitroso compound diethylnitrosamine (DEN) administered intraperitoneally (i.p.) induces liver neoplasms in rodents that reproducibly recapitulate some aspects of human hepatocarcinogenesis. In particular, DEN drives the stepwise ... ...

Abstract	The hepatotoxic N-nitroso compound diethylnitrosamine (DEN) administered intraperitoneally (i.p.) induces liver neoplasms in rodents that reproducibly recapitulate some aspects of human hepatocarcinogenesis. In particular, DEN drives the stepwise formation of pre-neoplastic and neoplastic (benign or malignant) hepatocellular lesions reminiscent of the initiation-promotion-progression sequence typical of chemical carcinogenesis. In humans, the development of hepatocellular carcinoma (HCC) is also a multi-step process triggered by continuous hepatocellular injury, chronic inflammation, and compensatory hyperplasia that fuel the emergence of dysplastic liver lesions followed by the formation of early HCC. The DEN-induced liver tumorigenesis model represents a versatile preclinical tool that enables the study of many tumor development modifiers (genetic background, gene knockout or overexpression, diets, pollutants, or drugs) with a thorough follow-up of the multistage process on live animals by means of high-resolution imaging. Here, we provide a comprehensive protocol for the induction of hepatocellular neoplasms in wild-type C57BL/6J male mice following i.p. DEN injection (25 mg/kg) at 14 days of age and 36 weeks feeding of a high-fat high-sucrose (HFHS) diet. We emphasize the use of ultrasound liver imaging to follow tumor development and provide histopathological correlations. We also discuss the extrinsic and intrinsic factors known to modify the course of liver tumorigenesis in this model.
MeSH term(s)	Humans ; Male ; Mice ; Animals ; Infant ; Carcinoma, Hepatocellular/pathology ; Liver Neoplasms/chemically induced ; Liver Neoplasms/diagnostic imaging ; Diethylnitrosamine/toxicity ; Mice, Inbred C57BL ; Carcinogenesis/pathology ; Diet, High-Fat/adverse effects ; Liver/diagnostic imaging ; Liver/pathology ; Ultrasonography
Chemical Substances	Diethylnitrosamine (3IQ78TTX1A)
Language	English
Publishing date	2024-02-05
Publishing country	United States
Document type	Journal Article
ISSN	1940-6029
ISSN (online)	1940-6029
DOI	10.1007/978-1-0716-3694-7_3
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Article ; Online: MRI Assessment of Tendon Graft After Lateral Ankle Ligament Reconstruction: Does Ligamentization Exist?

Cordier, Guillaume / Boudahmane, Sofiane / Ovigue, Jordan / Michels, Frederick / Araujo Nunes, Gustavo / Dallaudiere, Benjamin

The American journal of sports medicine

2024 Volume 52, Issue 3, Page(s) 721–729

Abstract: Background: No description exists in the literature about the normal evolution of tendon graft after a lateral ankle ligament (LAL) reconstruction.: Purpose: To assess the magnetic resonance imaging (MRI) characteristics and the evolution of the ... ...

Abstract	Background: No description exists in the literature about the normal evolution of tendon graft after a lateral ankle ligament (LAL) reconstruction. Purpose: To assess the magnetic resonance imaging (MRI) characteristics and the evolution of the tendon graft during different moments in the follow-up after an endoscopic reconstruction of the LAL. Study design: Cohort study; Level of evidence, 3. Methods: This prospective study included 37 consecutive patients who underwent an endoscopic reconstruction of the LAL with an autograft using the gracilis tendon to treat chronic ankle instability (CAI) resistant to nonoperative treatment (CAI group) and 16 patients without ankle instability (control group). All patients in the CAI group underwent a postoperative assessment at 6, 12, and 24 months using the Karlsson score and MRI examination. Only patients with good and excellent results were included in the study. Graft assessment consisted of qualitative measurements and quantitative evaluations of the reconstructed anterior talofibular ligament (RATFL) and reconstructed calcaneofibular ligament (RCFL), including signal-to-noise quotient (SNQ) and contrast-to-noise quotient (CNQ) measurements in proton density-fat suppressed (PD-FS) and T1-weighted sequences. The analysis of variance test was used to compare the SNQ and the CNQ at different time points for each sequence. Results: The MRI signal at 6 months was increased compared with that of the control group. Next, a significant signal decrease from 6 to 24 months was noted on PD-FS and T1-weighted images. SNQ measurements on PD-FS weighted images for both the RATFL and the RCFL demonstrated a significantly higher signal ( Conclusion: The present study demonstrated an evolution of the MRI characteristics, suggesting a process of graft maturation toward ligamentization. This is important for clinical practice, as it suggests an evolution in graft properties and supports the possibility of creating a viable ligament.
MeSH term(s)	Humans ; Lateral Ligament, Ankle/diagnostic imaging ; Lateral Ligament, Ankle/surgery ; Ankle ; Cohort Studies ; Prospective Studies ; Ligaments/diagnostic imaging ; Ligaments/surgery ; Joint Instability/diagnostic imaging ; Joint Instability/surgery ; Magnetic Resonance Imaging ; Protons ; Tendons/diagnostic imaging ; Tendons/surgery
Chemical Substances	Protons
Language	English
Publishing date	2024-02-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	197482-8
ISSN	1552-3365 ; 0363-5465
ISSN (online)	1552-3365
ISSN	0363-5465
DOI	10.1177/03635465231225487
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Article ; Online: Myxoid pleomorphic liposarcoma.

Fadaei, Sharareh / Cordier, Fleur / Ferdinande, Liesbeth / Van Dorpe, Jo / Creytens, David

Histology and histopathology

2024 , Page(s) 18724

Abstract: Myxoid pleomorphic liposarcoma (MPL) is an extremely rare adipocytic tumor, recently recognized as a distinct entity in the 5th edition of the World Health Organization (WHO) Classification of Soft Tissue and Bone Tumors. Predominantly found in the ... ...

Abstract	Myxoid pleomorphic liposarcoma (MPL) is an extremely rare adipocytic tumor, recently recognized as a distinct entity in the 5th edition of the World Health Organization (WHO) Classification of Soft Tissue and Bone Tumors. Predominantly found in the mediastinum of young women, MPLs exhibit a combination of histological features characteristic of myxoid liposarcoma and pleomorphic (lipo)sarcoma. Their unique molecular features distinguish MPLs from other liposarcomas. Unlike myxoid liposarcomas and well-differentiated/dedifferentiated liposarcomas, MPLs lack specific
Language	English
Publishing date	2024-02-26
Publishing country	Spain
Document type	Journal Article ; Review
ZDB-ID	83911-5
ISSN	1699-5848 ; 0213-3911
ISSN (online)	1699-5848
ISSN	0213-3911
DOI	10.14670/HH-18-724
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Article ; Online: PHOX2B: a diagnostic cornerstone in neurocristopathies and neuroblastomas.

Windels, Mei-Lan / Cordier, Fleur / Van Dorpe, Jo / Ferdinande, Liesbeth / Creytens, David

Journal of clinical pathology

2024

Abstract: Paired-like homeobox 2B ( ...

Abstract	Paired-like homeobox 2B (
Language	English
Publishing date	2024-03-08
Publishing country	England
Document type	Journal Article
ZDB-ID	80261-x
ISSN	1472-4146 ; 0021-9746
ISSN (online)	1472-4146
ISSN	0021-9746
DOI	10.1136/jcp-2023-209047
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Article ; Online: Maladies pulmonaires rares: de l'adoption des maladies orphelines à la structuration de la filière de soins.

Cottin, V / Cordier, J-F

Revue des maladies respiratoires

2014 Volume 31, Issue 10, Page(s) 889–892

Title translation	Rare pulmonary diseases: from the adoption of orphan diseases to structured healthcare networks.
MeSH term(s)	Community Networks/organization & administration ; France ; Health Planning Organizations/trends ; Humans ; International Cooperation ; Lung Diseases/classification ; Lung Diseases/epidemiology ; Lung Diseases/therapy ; Rare Diseases/classification ; Rare Diseases/epidemiology ; Rare Diseases/therapy ; Registries
Language	French
Publishing date	2014-12
Publishing country	France
Document type	Editorial ; Introductory Journal Article
ZDB-ID	605743-3
ISSN	1776-2588 ; 0301-0279 ; 0761-8425
ISSN (online)	1776-2588
ISSN	0301-0279 ; 0761-8425
DOI	10.1016/j.rmr.2014.10.725
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Zs.A 1945: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 94: Show issues

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Article: Amyloses et dépôts immunoglobuliniques non amyloïdes pulmonaires.

Cordier, J-F

Revue des maladies respiratoires

2008 Volume 25, Issue 6, Page(s) 743–765

Abstract: The amyloidoses are characterised histopathologically by the tissue deposition of fibrillar amyloid, specifically stained by Congo red and birefringent under polarised light. This characteristic is linked to a beta-folded structural configuration that is ...

Title translation	Pulmonary amyloidosis and non-amyloid immunoglobulin deposits.
Abstract	The amyloidoses are characterised histopathologically by the tissue deposition of fibrillar amyloid, specifically stained by Congo red and birefringent under polarised light. This characteristic is linked to a beta-folded structural configuration that is the common denominator of the amyloidoses which may have more than twenty distinct protein precursors. The most common is AL amyloidosis which is of immunoglobulin origin. It may be organ limited, or systemic (with predominant cardiac involvement). Limited bronchopulmonary amyloidosis, usually AL, may manifest itself as either tracheobronchial deposits or parenchymal nodules or masses. Diffuse interstitial pulmonary amyloidosis with clinical manifestations is rare and usually associated with systemic AL amyloidosis and deposits involving the alveolar-capillary gas exchange zone. Amyloidosis may also manifest itself as pulmonary hypertension, amyloid hilar and mediastinal adenopathy or pleural involvement. AL amyloidosis may be associated locally with pulmonary lymphoma. Occasionally, non-fibrillar, Congo red-negative, immunoglobulin deposits may occur, presenting as parenchymal pulmonary nodules or cysts. Exceptionally immunoglobulin deposits may show a cellular or extra-cellular crystalline structure.
MeSH term(s)	Amyloid ; Amyloidosis/diagnosis ; Amyloidosis/diagnostic imaging ; Amyloidosis/pathology ; Diagnosis, Differential ; Humans ; Immunoglobulin Light Chains/chemistry ; Immunoglobulin Light Chains/metabolism ; Immunoglobulin kappa-Chains/chemistry ; Immunoglobulin kappa-Chains/metabolism ; Lung/pathology ; Lung Diseases/diagnosis ; Lung Diseases/diagnostic imaging ; Lung Diseases/pathology ; Radiography, Thoracic ; Tomography, X-Ray Computed
Chemical Substances	Amyloid ; Immunoglobulin Light Chains ; Immunoglobulin kappa-Chains ; amyloid protein AL
Language	French
Publishing date	2008-08-27
Publishing country	France
Document type	Comparative Study ; Journal Article ; Review
ZDB-ID	605743-3
ISSN	0761-8425 ; 0301-0279
ISSN	0761-8425 ; 0301-0279
DOI	10.1016/s0761-8425(08)73803-8
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Zs.A 1945: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article: Cryptogenic organising pneumonia.

Cordier, J-F

The European respiratory journal

2006 Volume 28, Issue 2, Page(s) 422–446

Abstract: Organising pneumonia is defined histopathologically by intra-alveolar buds of granulation tissue, consisting of intermixed myofibroblasts and connective tissue. Although nonspecific, this histopathological pattern, together with characteristic clinical ... ...

Abstract	Organising pneumonia is defined histopathologically by intra-alveolar buds of granulation tissue, consisting of intermixed myofibroblasts and connective tissue. Although nonspecific, this histopathological pattern, together with characteristic clinical and imaging features, defines cryptogenic organising pneumonia when no cause or peculiar underlying context is found. Rapid clinical and imaging improvement is obtained with corticosteroid treatment, but relapses are common after stopping treatment.
MeSH term(s)	Cryptogenic Organizing Pneumonia/history ; Cryptogenic Organizing Pneumonia/metabolism ; Cryptogenic Organizing Pneumonia/pathology ; Cryptogenic Organizing Pneumonia/therapy ; Fibroblasts/metabolism ; Fibroblasts/pathology ; History, 20th Century ; History, 21st Century ; Humans ; Myoblasts/metabolism ; Myoblasts/pathology ; Pulmonary Alveoli/metabolism ; Pulmonary Alveoli/pathology ; Rare Diseases/history ; Rare Diseases/metabolism ; Rare Diseases/pathology
Keywords	covid19
Language	English
Publishing date	2006-08
Publishing country	England
Document type	Historical Article ; Journal Article ; Review
ZDB-ID	639359-7
ISSN	1399-3003 ; 0903-1936
ISSN (online)	1399-3003
ISSN	0903-1936
DOI	10.1183/09031936.06.00013505
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Zs.A 2322: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 292: Show issues

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Article ; Online: Spinal Syrinx Due to Lipiodol-Induced Arachnoiditis.

Paquet, Jan / Cordier, Fleur / Vandersteene, Jelle

World neurosurgery

2021 Volume 149, Page(s) 64–66

Abstract: We present a case of a progressive symptomatic intramedullary cyst, diagnosed decades after Lipiodol injection. Lipiodol was originally administered intrathecally for the radiologic diagnosis of spinal masses. A link between the lesion and the history of ...

Abstract	We present a case of a progressive symptomatic intramedullary cyst, diagnosed decades after Lipiodol injection. Lipiodol was originally administered intrathecally for the radiologic diagnosis of spinal masses. A link between the lesion and the history of Lipiodol injection was never suspected. Surgical exploration revealed a membrane above the lesion, separating the intradural space in a cranial and caudal compartment. On the level of the cyst, we identified glassy pearls containing a fatty liquid, compatible with Lipiodol deposits. We hypothesize that the syrinx is secondary to the impact of cerebrospinal fluid pulsations on the reactive membrane and that this membrane originated from an arachnoiditis caused by Lipiodol deposits. Lipiodol was indeed abandoned after it was found to cause arachnoiditis and neurologic sequelae. Despite the cessation of its usage, the causal role of Lipiodol in arachnoiditis and spinal cyst formation should still be considered, as symptoms may arise many years after Lipiodol administration.
MeSH term(s)	Arachnoiditis/chemically induced ; Arachnoiditis/diagnostic imaging ; Arachnoiditis/surgery ; Contrast Media/administration & dosage ; Contrast Media/adverse effects ; Cysts/chemically induced ; Cysts/diagnostic imaging ; Cysts/surgery ; Ethiodized Oil/administration & dosage ; Ethiodized Oil/adverse effects ; Female ; Humans ; Injections, Spinal/adverse effects ; Middle Aged ; Syringomyelia/chemically induced ; Syringomyelia/diagnostic imaging ; Syringomyelia/surgery
Chemical Substances	Contrast Media ; Ethiodized Oil (8008-53-5)
Language	English
Publishing date	2021-02-16
Publishing country	United States
Document type	Case Reports
ZDB-ID	2534351-8
ISSN	1878-8769 ; 1878-8750
ISSN (online)	1878-8769
ISSN	1878-8750
DOI	10.1016/j.wneu.2021.02.022
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Article ; Online: A case of a lipoblastoma with EEF1A1::PLAG1 fusion and metaplastic ossification.

Deolet, Ellen / Cordier, Fleur / Ferdinande, Liesbeth / Loontiens, Siebe / Van der Meulen, Joni / Van Dorpe, Jo / Creytens, David

Genes, chromosomes & cancer

2024 Volume 63, Issue 2, Page(s) e23225

MeSH term(s)	Humans ; Lipoblastoma ; Osteogenesis ; Peptide Elongation Factor 1 ; DNA-Binding Proteins
Chemical Substances	EEF1A1 protein, human ; Peptide Elongation Factor 1 ; PLAG1 protein, human ; DNA-Binding Proteins
Language	English
Publishing date	2024-03-12
Publishing country	United States
Document type	Letter
ZDB-ID	1018988-9
ISSN	1098-2264 ; 1045-2257
ISSN (online)	1098-2264
ISSN	1045-2257
DOI	10.1002/gcc.23225
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