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  1. Article ; Online: Visible light-induced photocatalytic and antibacterial adhesion properties of superhydrophilic TiO

    Zhou, Mingzhu / Zhang, Xingran / Quan, Yuanxia / Tian, Yu / Chen, Jie / Li, Li

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 7940

    Abstract: Bacterial infections triggered by patient or healthcare worker contact with surfaces are a major cause of medically acquired infections. By controlling the kinetics of tetrabutyl titanate hydrolysis and condensation during the sol-gel process, it is ... ...

    Abstract Bacterial infections triggered by patient or healthcare worker contact with surfaces are a major cause of medically acquired infections. By controlling the kinetics of tetrabutyl titanate hydrolysis and condensation during the sol-gel process, it is possible to regulate the content of Ti
    MeSH term(s) Humans ; Titanium/pharmacology ; Titanium/chemistry ; Catalysis ; Surface Properties ; Light ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry ; Nanoparticles/chemistry
    Chemical Substances Titanium (D1JT611TNE) ; Anti-Bacterial Agents
    Language English
    Publishing date 2024-04-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-58660-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Sacculatane Diterpenoids from the Liverwort

    Han, Jingjing / Sun, Yan / Zhou, Jinchuan / Li, Yi / Jin, Xueyang / Zhu, Mingzhu / Xu, Zejun / Zhang, Jiaozhen / Lou, Hongxiang

    Journal of natural products

    2024  

    Abstract: Seven new terpenoids, including six sacculatane diterpenoids plagiochilarins A-F ( ...

    Abstract Seven new terpenoids, including six sacculatane diterpenoids plagiochilarins A-F (
    Language English
    Publishing date 2024-02-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 304325-3
    ISSN 1520-6025 ; 0163-3864
    ISSN (online) 1520-6025
    ISSN 0163-3864
    DOI 10.1021/acs.jnatprod.4c00071
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Collateral-Pricking and Bloodletting Cupping Combined with Electroacupuncture for Postherpetic Neuralgia: A Meta-Analysis.

    Yang, Yueyuan / Xu, Wenting / Li, Mingzhu / Zhou, Yi / Qian, Yu

    Alternative therapies in health and medicine

    2024  

    Abstract: Background: Acupuncture therapy has demonstrated significant efficacy in the treatment of postherpetic neuralgia, effectively alleviating pain intensity and enhancing patients' quality of life. However, the effectiveness of collateral-pricking and ... ...

    Abstract Background: Acupuncture therapy has demonstrated significant efficacy in the treatment of postherpetic neuralgia, effectively alleviating pain intensity and enhancing patients' quality of life. However, the effectiveness of collateral-pricking and bloodletting cupping combined with electroacupuncture in the treatment of postherpetic neuralgia remains a subject of controversy. We aimed to assess the efficacy and safety of collateral-pricking and bloodletting cupping combined with electroacupuncture for postherpetic neuralgia.
    Methods: We identified relevant randomized controlled trials by conducting a comprehensive search in multiple databases: China National Knowledge Infrastructure, China Biomedical Literature, Wanfang Data, PubMed, Cochrane Central Register of Controlled Trials, Embase, and Web of Science. The outcome included efficacy rate, visual analog scale (VAS)scores and pittsburgh sleep quality index (PSQI) scores. We meticulously assessed the risk of bias in the included trials and performed a meta-analysis.
    Results: We analyzed 9 randomized controlled trials involving 639 patients. Collateral-pricking and bloodletting cupping combined with electroacupuncture achieved a significantly higher efficacy rate (risk ratio, 1.22 [95% CI, 1.13-1.31]; P < .001), reduced theVAS scores (standardized mean difference, -1.52 [95% CI, -2.26 to -0.79]; P < .001), and improved the PSQI scores (standardized mean difference, -2.31 [95% CI, -3.97 to -0.64]; P = .007) compared with the control groups. The subgroup analysis revealed that the combined treatment of collateral-pricking and bloodletting cupping and electroacupuncture had a significantly higher total effective rate compared with the carbamazepine, electroacupuncture, and pregabalin groups (P < .05). The total efficacy rate of the collateral-pricking and bloodletting cupping combined with electroacupuncture group was superior to that of the control group, irrespective of whether 2 or 3 courses were administered (P < .05).
    Conclusion: Existing evidence suggests that the combination of collateral-pricking and bloodletting cupping and electroacupuncture demonstrates efficacy in pain relief, improvement of sleep quality, and enhanced therapeutic outcomes for patients with postherpetic neuralgia. However, further validation through large-scale multicenter randomized controlled trials is warranted due to the limited quantity and quality of the included literature in this study.
    Language English
    Publishing date 2024-03-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1225073-9
    ISSN 1078-6791
    ISSN 1078-6791
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Exosomal circ_0000722 derived from periodontal ligament stem cells undergoing osteogenic differentiation promotes osteoclastogenesis.

    Xie, Liangkun / Ren, Xuefeng / Yang, Zijie / Zhou, Ting / Zhang, Mingzhu / An, Wei / Guan, Zheng

    International immunopharmacology

    2024  Volume 128, Page(s) 111520

    Abstract: Periodontal ligament stem cells (PDLSCs), which are considered promising stem cells for regeneration of periodontal bony tissue, can also manipulate alveolar bone remodeling by exosomes. In this study, we investigated interactions between PDLSCs under ... ...

    Abstract Periodontal ligament stem cells (PDLSCs), which are considered promising stem cells for regeneration of periodontal bony tissue, can also manipulate alveolar bone remodeling by exosomes. In this study, we investigated interactions between PDLSCs under osteogenic differentiation and osteoclast precursors. The results showed that conditioned medium from PDLSCs under 5d osteogenic induction promoted osteoclastogenesis of RAW264.7 cells. The exosomes extracted from those conditioned media showed similar effects on osteoclastogenesis. Furthermore, exosomes from PDLSCs under 5d of osteogenic induction showed significantly high expression of circ_0000722, compared with exosomes from PDLSCs before osteogenic induction. Downregulation of circ_0000722 significantly attenuated the effect of PDLSC-derived exosomes on the osteoclastogenesis of RAW264.7 cells. Our findings suggested that exosomal circ_0000722 derived from periodontal ligament stem cells undergoing osteogenic differentiation might promote osteoclastogenesis by upregulating TRAF6 expression and activating downstream NF-κB and AKT signaling pathways.
    MeSH term(s) Osteogenesis ; Periodontal Ligament ; Cells, Cultured ; Stem Cells ; Cell Differentiation
    Language English
    Publishing date 2024-01-09
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2043785-7
    ISSN 1878-1705 ; 1567-5769
    ISSN (online) 1878-1705
    ISSN 1567-5769
    DOI 10.1016/j.intimp.2024.111520
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  5. Article ; Online: A closed-loop process for spent washing solution from multi-metal contaminated soil: EDTA reclamation and recycling.

    Ding, Lei / Yuan, Mingzhu / Li, Shuang / Zhou, Jianmin / Wu, Siyu / Zhao, Jianfeng / Cui, Changzheng

    Chemosphere

    2024  Volume 352, Page(s) 141461

    Abstract: The proper disposal of spent soil washing solution is a great challenge to ethylenediamine tetraacetate (EDTA)-base soil washing technologies, particularly when the solution contains multi-metals. In this paper, we proposed an environmentally friendly ... ...

    Abstract The proper disposal of spent soil washing solution is a great challenge to ethylenediamine tetraacetate (EDTA)-base soil washing technologies, particularly when the solution contains multi-metals. In this paper, we proposed an environmentally friendly disposal of multi-metal spent washing solution, in which the multi-metals were concentrated as hazardous precipitates for further safe disposal, and EDTA was reclaimed and recycled to further wash contaminated soil together with the cleansed process water. The results showed that Cr
    MeSH term(s) Edetic Acid ; Soil ; Soil Pollutants/analysis ; Metals, Heavy/analysis ; Chelating Agents ; Water ; Environmental Restoration and Remediation
    Chemical Substances Edetic Acid (9G34HU7RV0) ; Soil ; Soil Pollutants ; Metals, Heavy ; Chelating Agents ; Water (059QF0KO0R)
    Language English
    Publishing date 2024-02-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2024.141461
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Effects of Smartphone-Based Remote Interventions on Dietary Intake, Physical Activity, Weight Control, and Related Health Benefits Among the Older Population With Overweight and Obesity in China: Randomized Controlled Trial.

    Zhang, Na / Zhou, Mingzhu / Li, Muxia / Ma, Guansheng

    Journal of medical Internet research

    2023  Volume 25, Page(s) e41926

    Abstract: Background: Traditional health management requires many human and material resources and cannot meet the growing needs. Remote medical technology provides an opportunity for health management; however, the research on it is insufficient.: Objective: ... ...

    Abstract Background: Traditional health management requires many human and material resources and cannot meet the growing needs. Remote medical technology provides an opportunity for health management; however, the research on it is insufficient.
    Objective: The objective of this study was to assess the effects of remote interventions on weight management.
    Methods: In this randomized controlled study, 750 participants were randomly assigned to a remote dietary and physical activity intervention group (group DPI), remote physical activity intervention group (group PI), or control group (group C). At baseline (time 1), day 45 (time 2), and day 90 (time 3), data were collected, including data on dietary intake, physical activity, indexes related to weight control, and health benefits.
    Results: A total of 85.6% (642/750) of participants completed the follow-up. Compared with group C, group DPI showed a significant decrease in energy intake (-581 vs -82 kcal; P<.05), protein intake (-17 vs -3 g; P<.05), fat intake (-8 vs 3 g; P<.05), and carbohydrate intake (-106.5 vs -4.7 g; P<.05) at time 3. Compared with time 1, groups DPI and PI showed a significant decrease in cereal and potato intake (P<.05). Compared with time 1, the physical activity levels related to transportation (group PI: 693 vs 597 metabolic equivalent [MET]-min/week, group C: 693 vs 594 MET-min/week; P<.05) and housework and gardening (group PI: 11 vs 0 MET-min/week, group C: 11 vs 4 MET-min/week; P<.05) in groups PI and C were improved at time 3. Compared with groups PI and C, group DPI showed a significant decrease in weight (-1.56 vs -0.86 kg and -1.56 vs -0.66 kg, respectively; P<.05) and BMI (-0.61 vs -0.33 kg/m
    Conclusions: Remote dietary and physical activity interventions can improve dietary intake among participants with overweight and obesity, are beneficial for weight control, and have potential health benefits.
    Trial registration: Chinese Clinical Trial Registry ChiCTR1900023355; https://www.chictr.org.cn/showproj.html?proj=38976.
    MeSH term(s) Humans ; Eating ; Exercise/physiology ; Obesity/therapy ; Overweight/therapy ; Smartphone ; Triglycerides
    Chemical Substances Triglycerides
    Language English
    Publishing date 2023-04-28
    Publishing country Canada
    Document type Randomized Controlled Trial ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2028830-X
    ISSN 1438-8871 ; 1438-8871
    ISSN (online) 1438-8871
    ISSN 1438-8871
    DOI 10.2196/41926
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  7. Article ; Online: Comparative study of the hydrogen bonding interactions between ester-functionalized/non-functionalized imidazolium-based ionic liquids and DMSO.

    Jiang, Yuxin / Xu, Xianzhen / Wang, Mingzhu / Zhou, Yu / Wang, Zonghua

    Physical chemistry chemical physics : PCCP

    2023  Volume 25, Issue 12, Page(s) 8789–8798

    Abstract: There have been some studies on the microscopic properties of ester-functionalized ionic liquids (ILs), but the microscopic properties of their mixtures with co-solvents have seldom been reported. In practical applications, ILs are usually used together ... ...

    Abstract There have been some studies on the microscopic properties of ester-functionalized ionic liquids (ILs), but the microscopic properties of their mixtures with co-solvents have seldom been reported. In practical applications, ILs are usually used together with co-solvents. Therefore, it is very important to study the microstructure of ester-functionalized ILs and co-solvents. In this work, the hydrogen bonding interactions between ester-functionalized IL 1-acetoxyethyl-3-methylimidazolium tetrafluoroborate (AOEMIMBF
    Language English
    Publishing date 2023-03-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/d2cp05048j
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  8. Article ; Online: Chromatin region binning of gene expression for improving embryo cell subtype identification.

    Liang, Pengfei / Li, Hanshuang / Long, Chunshen / Liu, Mingzhu / Zhou, Jian / Zuo, Yongchun

    Computers in biology and medicine

    2024  Volume 170, Page(s) 108049

    Abstract: Mammalian embryonic development is a complex process, characterized by intricate spatiotemporal dynamics and distinct chromatin preferences. However, the quick diversification in early embryogenesis leads to significant cellular diversity and the ... ...

    Abstract Mammalian embryonic development is a complex process, characterized by intricate spatiotemporal dynamics and distinct chromatin preferences. However, the quick diversification in early embryogenesis leads to significant cellular diversity and the sparsity of scRNA-seq data, posing challenges in accurately determining cell fate decisions. In this study, we introduce a chromatin region binning method using scChrBin, designed to identify chromatin regions that elucidate the dynamics of embryonic development and lineage differentiation. This method transforms scRNA-seq data into a chromatin-based matrix, leveraging genomic annotations. Our results showed that the scChrBin method achieves high accuracy, with 98.0% and 89.2% on two single-cell embryonic datasets, demonstrating its effectiveness in analyzing complex developmental processes. We also systematically and comprehensively analysis of these key chromatin binning regions and their associated genes, focusing on their roles in lineage and stage development. The perspective of chromatin region binning method enables a comprehensive analysis of transcriptome data at the chromatin level, allowing us to unveil the dynamic expression of chromatin regions across temporal and spatial development. The tool is available as an application at https://github.com/liameihao/scChrBin.
    MeSH term(s) Animals ; Female ; Pregnancy ; Chromatin/genetics ; Embryonic Development/genetics ; Cell Differentiation/genetics ; Transcriptome ; Genome ; Gene Expression Profiling ; Sequence Analysis, RNA ; Mammals/genetics
    Chemical Substances Chromatin
    Language English
    Publishing date 2024-01-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 127557-4
    ISSN 1879-0534 ; 0010-4825
    ISSN (online) 1879-0534
    ISSN 0010-4825
    DOI 10.1016/j.compbiomed.2024.108049
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  9. Article ; Online: Recent advances in 3D bioprinted cartilage-mimicking constructs for applications in tissue engineering.

    Zhou, Jian / Li, Qi / Tian, Zhuang / Yao, Qi / Zhang, Mingzhu

    Materials today. Bio

    2023  Volume 23, Page(s) 100870

    Abstract: Human cartilage tissue can be categorized into three types: hyaline cartilage, elastic cartilage and fibrocartilage. Each type of cartilage tissue possesses unique properties and functions, which presents a significant challenge for the regeneration and ... ...

    Abstract Human cartilage tissue can be categorized into three types: hyaline cartilage, elastic cartilage and fibrocartilage. Each type of cartilage tissue possesses unique properties and functions, which presents a significant challenge for the regeneration and repair of damaged tissue. Bionics is a discipline in which humans study and imitate nature. A bionic strategy based on comprehensive knowledge of the anatomy and histology of human cartilage is expected to contribute to fundamental study of core elements of tissue repair. Moreover, as a novel tissue-engineered technology, 3D bioprinting has the distinctive advantage of the rapid and precise construction of targeted models. Thus, by selecting suitable materials, cells and cytokines, and by leveraging advanced printing technology and bionic concepts, it becomes possible to simultaneously realize multiple beneficial properties and achieve improved tissue repair. This article provides an overview of key elements involved in the combination of 3D bioprinting and bionic strategies, with a particular focus on recent advances in mimicking different types of cartilage tissue.
    Language English
    Publishing date 2023-11-17
    Publishing country England
    Document type Journal Article ; Review
    ISSN 2590-0064
    ISSN (online) 2590-0064
    DOI 10.1016/j.mtbio.2023.100870
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  10. Article: Preparation, Structural Characterization, and Stability of Low-Molecular-Weight Collagen Peptides-Calcium Chelate Derived from Tuna Bones.

    Zhong, Yaqi / Zhou, Yufang / Ma, Mingzhu / Zhao, Yadong / Xiang, Xingwei / Shu, Conghan / Zheng, Bin

    Foods (Basel, Switzerland)

    2023  Volume 12, Issue 18

    Abstract: This study was conducted to prepare calcium chelate of low-molecular-weight tuna bone collagen peptides ( ... ...

    Abstract This study was conducted to prepare calcium chelate of low-molecular-weight tuna bone collagen peptides (TBCP
    Language English
    Publishing date 2023-09-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods12183403
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